iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007819

Ensembl Protein ID

AAS52978

UniProt Accession

Q756G9; GCN5_ASHGO

Genbank Protein ID

AAS52978.1

Protein Name

Histone acetyltransferase GCN5

Genbank Nucleotide ID

AE016818

Gene Name

GCN5; AER297C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_AER297C	AAS52978	AAS52978

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	48.31	7.00e-86	315.00	IUUC-Hsa-046970

Active Site

Position(s)	Description	Evidence
186	Proton donor/acceptor	{ECO:0000250\|UniProtKB:Q92830}

Organism

Ashbya gossypii

Functional Description
(View)

Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, with a lower preference histone H4 to form H4K8ac and H4K16ac, and contributes to H2A.Z acetylation. Acetylation of histones gives a specific tag for epigenetic transcription activation (By similarity).

Protein Sequence
(Fasta)

MSMPLKRRNK QSQGNEPKKI KVEEQEAEEK ISEDIPVTDL KEPEALADIQ STSGGDEVSE 60
GAQGDADPAE KSVGGLKEEV EDEEKGIVKF MFDGVEYKFR ERPSVIEEKE GKIEFRVVNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCATGC CGTTGAAAAG AAGGAACAAA CAAAGTCAGG GAAATGAACC AAAGAAAATA 60
AAAGTTGAAG AGCAGGAGGC AGAGGAAAAG ATTAGCGAAG ACATACCTGT TACAGATCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0010--Activator
KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR000182--GNAT_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51186--GNAT

Pfam

PF00583--Acetyltransf_1
PF00439--Bromodomain

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO

Gene Ontology

GO:0000124--C:SAGA complex
GO:0010484--F:H3 histone acetyltransferase activity
GO:0006338--P:chromatin remodeling
GO:0060358--P:negative regulation of leucine import
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0007131--P:reciprocal meiotic recombination
GO:0006351--P:transcription, DNA-templated

KEGG

ago:AGOS_AER297C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001599	Ailuropoda melanoleuca	48.67	1.00e-79	288.00
IUUC-Atr-003130	Amborella trichopoda	44.74	3.00e-92	330.00
IUUC-Apl-004026	Anas platyrhynchos	49.56	2.00e-86	311.00
IUUC-Aca-005148	Anolis carolinensis	47.42	2.00e-24	106.00
IUUC-Aly-006486	Arabidopsis lyrata	46.54	1.00e-82	298.00
IUUC-Ath-006763	Arabidopsis thaliana	46.13	8.00e-83	298.00
IUUC-Acl-008194	Aspergillus clavatus	66.86	1.00e-146	510.00
IUUC-Afl-008546	Aspergillus flavus	66.00	1.00e-145	506.00
IUUC-Afu-009124	Aspergillus fumigatus	67.43	7.00e-148	514.00
IUUC-Ani-009432	Aspergillus nidulans	65.06	1.00e-136	477.00
IUUC-Ang-009824	Aspergillus niger	66.67	5.00e-148	514.00
IUUC-Aor-010076	Aspergillus oryzae	64.82	7.00e-145	504.00
IUUC-Ate-010568	Aspergillus terreus	50.00	1.30e+00	25.00
IUUC-Ame-010924	Astyanax mexicanus	47.42	2.00e-24	107.00
IUUC-Bgr-012003	Blumeria graminis	63.94	3.00e-138	482.00
IUUC-Bta-012381	Bos taurus	47.65	2.00e-83	301.00
IUUC-Bci-013974	Botrytis cinerea	61.69	9.00e-138	481.00
IUUC-Bdi-015016	Brachypodium distachyon	48.20	3.00e-92	330.00
IUUC-Bol-015982	Brassica oleracea	38.03	8.00e-08	51.60
IUUC-Bra-017875	Brassica rapa	38.03	2.00e-07	50.40
IUUC-Cel-018633	Caenorhabditis elegans	38.68	3.00e-68	250.00
IUUC-Cja-019375	Callithrix jacchus	48.67	1.00e-79	288.00
IUUC-Cfa-020400	Canis familiaris	48.67	2.00e-79	288.00
IUUC-Cpo-021686	Cavia porcellus	48.53	5.00e-85	306.00
IUUC-Cre-023019	Chlamydomonas reinhardtii	40.54	1.00e-87	314.00
IUUC-Csa-024252	Chlorocebus sabaeus	48.82	2.00e-85	307.00
IUUC-Cho-024635	Choloepus hoffmanni	58.02	6.00e-37	146.00
IUUC-Cin-025450	Ciona intestinalis	41.67	1.00e-20	92.40
IUUC-Csv-026235	Ciona savignyi	34.62	2.00e-21	93.20
IUUC-Cgl-026660	Colletotrichum gloeosporioides	66.76	2.00e-144	502.00
IUUC-Cne-027050	Cryptococcus neoformans	49.62	8.00e-104	369.00
IUUC-Cme-027342	Cyanidioschyzon merolae	26.26	1.00e+00	27.70
IUUC-Dre-027468	Danio rerio	47.04	7.00e-82	296.00
IUUC-Dno-029306	Dasypus novemcinctus	48.67	4.00e-85	306.00
IUUC-Dor-030465	Dipodomys ordii	38.19	9.00e-43	166.00
IUUC-Dse-031386	Dothistroma septosporum	59.40	5.00e-129	451.00
IUUC-Dme-032140	Drosophila melanogaster	50.00	1.00e-25	111.00
IUUC-Ete-032789	Echinops telfairi	46.39	1.00e-23	105.00
IUUC-Eca-034212	Equus caballus	48.67	2.00e-79	288.00
IUUC-Eeu-034605	Erinaceus europaeus	56.49	9.00e-36	143.00
IUUC-Fca-035972	Felis catus	48.67	2.00e-85	307.00
IUUC-Fal-037223	Ficedula albicollis	48.97	3.00e-85	307.00
IUUC-Fox-037874	Fusarium oxysporum	65.42	7.00e-138	481.00
IUUC-Fso-038286	Fusarium solani	65.91	2.00e-140	489.00
IUUC-Gmo-039102	Gadus morhua	45.80	5.00e-79	286.00
IUUC-Ggr-039925	Gaeumannomyces graminis	53.72	2.00e-134	469.00
IUUC-Gga-041181	Gallus gallus	49.85	1.00e-87	315.00
IUUC-Gac-041887	Gasterosteus aculeatus	45.82	2.00e-78	285.00
IUUC-Gma-043540	Glycine max	48.07	2.00e-92	330.00
IUUC-Ggo-044607	Gorilla gorilla	48.82	2.00e-85	308.00
IUUC-Hsa-046970	Homo sapiens	48.82	1.00e-85	308.00
IUUC-Hvu-047105	Hordeum vulgare	56.68	1.00e-58	218.00
IUUC-Itr-048740	Ictidomys tridecemlineatus	47.42	4.00e-24	105.00
IUUC-Kpa-049146	Komagataella pastoris	65.32	1.00e-170	590.00
IUUC-Lch-049478	Latimeria chalumnae	48.97	8.00e-86	309.00
IUUC-Lpe-051678	Leersia perrieri	48.57	1.00e-82	298.00
IUUC-Loc-052255	Lepisosteus oculatus	46.61	3.00e-83	301.00
IUUC-Laf-054575	Loxodonta africana	48.67	3.00e-79	287.00
IUUC-Mcc-055161	Macaca mulatta	48.82	2.00e-85	308.00
IUUC-Meu-055990	Macropus eugenii	31.53	8.00e-14	70.90
IUUC-Mor-057026	Magnaporthe oryzae	59.60	2.00e-135	473.00
IUUC-Mpo-057590	Magnaporthe poae	60.17	6.00e-135	471.00
IUUC-Mtr-057835	Medicago truncatula	48.84	9.00e-88	315.00
IUUC-Mla-058950	Melampsora laricipopulina	59.39	4.00e-113	398.00
IUUC-Mga-060204	Meleagris gallopavo	46.39	1.00e-22	101.00
IUUC-Mvi-060295	Microbotryum violaceum	61.52	4.00e-128	449.00
IUUC-Mmr-060643	Microcebus murinus	46.90	3.00e-79	287.00
IUUC-Mdo-062732	Monodelphis domestica	48.97	7.00e-86	309.00
IUUC-Mmu-064125	Mus musculus	48.67	7.00e-79	286.00
IUUC-Mac-064798	Musa acuminata	40.26	6.00e-10	58.90
IUUC-Mpu-066371	Mustela putorius furo	48.82	2.00e-85	307.00
IUUC-Mlu-067447	Myotis lucifugus	47.79	1.00e-83	301.00
IUUC-Nfi-068373	Neosartorya fischeri	67.51	7.00e-151	524.00
IUUC-Ncr-068652	Neurospora crassa	66.76	5.00e-143	498.00
IUUC-Nle-069659	Nomascus leucogenys	48.82	2.00e-85	308.00
IUUC-Opr-070678	Ochotona princeps	30.34	3.00e-12	65.90
IUUC-Ont-071244	Oreochromis niloticus	46.94	5.00e-81	293.00
IUUC-Oan-072794	Ornithorhynchus anatinus	49.56	1.00e-86	311.00
IUUC-Ocu-074701	Oryctolagus cuniculus	48.67	2.00e-79	288.00
IUUC-Oba-075479	Oryza barthii	51.14	4.00e-71	259.00
IUUC-Obr-076214	Oryza brachyantha	33.78	8.00e-09	55.10
IUUC-Ogl-076970	Oryza glaberrima	48.04	3.00e-85	306.00
IUUC-Ogu-079017	Oryza glumaepatula	33.33	6.00e-09	55.10
IUUC-Oin-079610	Oryza indica	51.14	4.00e-71	259.00
IUUC-Olo-080777	Oryza longistaminata	33.33	6.00e-09	55.10
IUUC-Ome-081474	Oryza meridionalis	33.33	6.00e-09	55.10
IUUC-Oni-083016	Oryza nivara	48.21	2.00e-84	304.00
IUUC-Opu-083976	Oryza punctata	48.74	5.00e-86	309.00
IUUC-Oru-085067	Oryza rufipogon	33.33	6.00e-09	55.50
IUUC-Osa-085814	Oryza sativa	48.04	3.00e-85	306.00
IUUC-Ola-087071	Oryzias latipes	46.90	2.00e-80	291.00
IUUC-Olu-087711	Ostreococcus lucimarinus	43.30	3.00e-86	309.00
IUUC-Oga-089043	Otolemur garnettii	48.08	3.00e-79	287.00
IUUC-Oar-089893	Ovis aries	48.24	2.00e-84	305.00
IUUC-Ptr-090629	Pan troglodytes	48.82	2.00e-85	308.00
IUUC-Pan-092305	Papio anubis	48.54	4.00e-84	303.00
IUUC-Psi-093574	Pelodiscus sinensis	48.53	1.00e-83	301.00
IUUC-Pma-094160	Petromyzon marinus	46.31	5.00e-83	300.00
IUUC-Ppa-095410	Physcomitrella patens	44.11	5.00e-85	306.00
IUUC-Pfo-097043	Poecilia formosa	46.94	2.00e-81	295.00
IUUC-Pab-098748	Pongo abelii	48.82	2.00e-85	307.00
IUUC-Pop-099371	Populus trichocarpa	40.00	2.00e-07	50.80
IUUC-Pca-100223	Procavia capensis	47.35	8.00e-84	302.00
IUUC-Ppe-101832	Prunus persica	48.32	7.00e-94	335.00
IUUC-Pva-102122	Pteropus vampyrus	48.67	8.00e-80	289.00
IUUC-Pte-104228	Pyrenophora teres	56.82	6.00e-133	464.00
IUUC-Pyt-104702	Pyrenophora triticirepentis	56.82	3.00e-133	465.00
IUUC-Rno-105749	Rattus norvegicus	47.42	3.00e-24	106.00
IUUC-Sce-106432	Saccharomyces cerevisiae	79.21	0.00e+00	717.00
IUUC-Sha-107338	Sarcophilus harrisii	49.26	7.00e-86	309.00
IUUC-Spo-108273	Schizosaccharomyces pombe	64.27	5.00e-146	508.00
IUUC-Ssl-108545	Sclerotinia sclerotiorum	61.97	2.00e-133	466.00
IUUC-Smo-109385	Selaginella moellendorffii	44.72	2.00e-89	320.00
IUUC-Sit-110222	Setaria italica	49.16	4.00e-86	309.00
IUUC-Sly-111498	Solanum lycopersicum	49.61	4.00e-68	249.00
IUUC-Sar-113574	Sorex araneus	48.38	2.00e-78	284.00
IUUC-Sbi-114471	Sorghum bicolor	49.58	7.00e-89	318.00
IUUC-Sre-114915	Sporisorium reilianum	56.67	4.00e-138	483.00
IUUC-Ssc-116097	Sus scrofa	48.67	2.00e-79	288.00
IUUC-Tgu-116699	Taeniopygia guttata	49.26	2.00e-85	308.00
IUUC-Tru-118001	Takifugu rubripes	45.56	3.00e-79	287.00
IUUC-Tsy-118910	Tarsius syrichta	42.65	4.00e-68	250.00
IUUC-Tni-119684	Tetraodon nigroviridis	46.36	2.00e-79	288.00
IUUC-Tca-121066	Theobroma cacao	46.26	2.00e-90	324.00
IUUC-Tre-122112	Trichoderma reesei	65.62	3.00e-142	496.00
IUUC-Tvi-122355	Trichoderma virens	59.51	2.00e-142	496.00
IUUC-Tae-123931	Triticum aestivum	47.78	2.00e-83	301.00
IUUC-Tur-126587	Triticum urartu	47.17	1.00e-83	301.00
IUUC-Tme-126963	Tuber melanosporum	66.57	5.00e-149	518.00
IUUC-Tbe-127304	Tupaia belangeri	42.77	3.00e-68	251.00
IUUC-Ttr-128536	Tursiops truncatus	48.08	2.00e-78	284.00
IUUC-Uma-129538	Ustilago maydis	54.61	1.00e-137	481.00
IUUC-Vda-129860	Verticillium dahliae	65.44	3.00e-147	512.00
IUUC-Vpa-130239	Vicugna pacos	36.28	3.00e-48	184.00
IUUC-Vvi-130897	Vitis vinifera	43.91	1.00e-93	334.00
IUUC-Xtr-132300	Xenopus tropicalis	48.08	3.00e-84	304.00
IUUC-Xma-134105	Xiphophorus maculatus	46.61	9.00e-82	295.00
IUUC-Yli-134345	Yarrowia lipolytica	77.60	0.00e+00	625.00
IUUC-Zma-135384	Zea mays	49.44	2.00e-87	313.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence