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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063541
UUCD1 version UUC-MuM-00233
Ensembl Protein ID ENSMUSP00000122395.1
UniProt Accession Q91ZU0; G3UVX4; ASB7_MOUSE
Genbank Protein ID AAK97490.1; EDL07214.1
Protein Name Ankyrin repeat and SOCS box protein 7
Genbank Nucleotide ID AF398968; AC115761
Gene Name Asb7
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000030509.17 ENSMUST00000131320.7 ENSMUSP00000115921.1
ENSMUSG00000030509.17 ENSMUST00000124899.7 ENSMUSP00000122395.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
PhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box 7.70e-19 68.4 268 315
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box
   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyed 51
           l+ ++++pr+Lq+LCR++Ir+c+g q+lk++d+LP+ k++kdYL+++ 
   Q: 268  LQDVTRQPRTLQDLCRIKIRQCIGLQNLKLLDELPIAKVMKDYLKHKF 315
           677899****************************************95 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Sequence
(Fasta)
MLHHHCRRNP ELQEELQIQA AVAAGDVHTV RKMLEQGYSP NGRDANGWTL LHFSAARGKE 60
RCVRVFLEHG ADPTVKDLIG GFTALHYAAM HGRARIARLM LESEYRSDII NAKSNDGWTP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063541|E3,SOCS|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGCGGCAGCT GATTGGCTGT CGAAGGCTTG GTCCCATCCC AGTGACCCCA AAGTGCTGGA 60
AGGAGGGGGC GGGGGTGGCC CAGTGCAAAG TGCATCCCGA AAGCCCCCTG TCGGGACACC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063541|E3,SOCS|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR001496--SOCS_box
PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50225--SOCS
Pfam

PF12796--Ank_2
PF07525--SOCS_box
PRINTS

PR01415--ANKYRIN
SMART

SM00248--ANK
SM00253--SOCS
SM00969--SOCS_box
Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0016567--P:protein ubiquitination
KEGG mmu:117589
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000539 Aegilops tauschii 29.41 2.00e-17 83.20
IUUC-Aml-001863 Ailuropoda melanoleuca 98.14 0.00e+00 652.00
IUUC-Apl-003527 Anas platyrhynchos 98.75 0.00e+00 652.00
IUUC-Aca-004849 Anolis carolinensis 98.11 0.00e+00 653.00
IUUC-Ame-011273 Astyanax mexicanus 92.77 5.00e-180 623.00
IUUC-Bta-012762 Bos taurus 99.37 0.00e+00 658.00
IUUC-Bdi-014839 Brachypodium distachyon 29.46 1.00e-16 81.30
IUUC-Cja-019889 Callithrix jacchus 98.95 9.00e-170 588.00
IUUC-Cfa-021240 Canis familiaris 99.37 0.00e+00 658.00
IUUC-Cpo-021783 Cavia porcellus 99.37 0.00e+00 658.00
IUUC-Csa-023934 Chlorocebus sabaeus 99.37 0.00e+00 658.00
IUUC-Cho-024313 Choloepus hoffmanni 98.74 0.00e+00 653.00
IUUC-Dre-027494 Danio rerio 92.45 1.00e-179 622.00
IUUC-Dor-030507 Dipodomys ordii 99.37 0.00e+00 658.00
IUUC-Ete-032364 Echinops telfairi 98.43 0.00e+00 646.00
IUUC-Eca-033549 Equus caballus 99.06 0.00e+00 655.00
IUUC-Fca-035963 Felis catus 99.37 0.00e+00 658.00
IUUC-Fal-037425 Ficedula albicollis 98.74 0.00e+00 654.00
IUUC-Gmo-039083 Gadus morhua 88.99 2.00e-172 598.00
IUUC-Gga-040499 Gallus gallus 99.06 0.00e+00 656.00
IUUC-Gac-042002 Gasterosteus aculeatus 89.94 5.00e-174 603.00
IUUC-Gma-043361 Glycine max 26.74 5.00e-16 79.00
IUUC-Ggo-045128 Gorilla gorilla 99.37 0.00e+00 658.00
IUUC-Hsa-046854 Homo sapiens 99.37 0.00e+00 658.00
IUUC-Hvu-047098 Hordeum vulgare 28.81 2.00e-16 80.50
IUUC-Itr-048086 Ictidomys tridecemlineatus 99.30 3.00e-170 590.00
IUUC-Lch-050335 Latimeria chalumnae 96.23 0.00e+00 638.00
IUUC-Loc-051896 Lepisosteus oculatus 96.23 0.00e+00 644.00
IUUC-Laf-053453 Loxodonta africana 99.37 0.00e+00 658.00
IUUC-Mcc-054654 Macaca mulatta 99.37 0.00e+00 658.00
IUUC-Mtr-058135 Medicago truncatula 28.21 3.00e-18 86.70
IUUC-Mga-059478 Meleagris gallopavo 99.06 0.00e+00 656.00
IUUC-Mmr-060770 Microcebus murinus 99.37 0.00e+00 658.00
IUUC-Mdo-061889 Monodelphis domestica 99.06 0.00e+00 656.00
IUUC-Mpu-066042 Mustela putorius furo 99.37 0.00e+00 658.00
IUUC-Mlu-067745 Myotis lucifugus 97.17 0.00e+00 644.00
IUUC-Nle-069597 Nomascus leucogenys 99.37 0.00e+00 658.00
IUUC-Opr-071125 Ochotona princeps 98.74 0.00e+00 654.00
IUUC-Oan-072883 Ornithorhynchus anatinus 99.06 0.00e+00 655.00
IUUC-Ocu-074304 Oryctolagus cuniculus 99.06 0.00e+00 658.00
IUUC-Ola-087334 Oryzias latipes 87.97 2.00e-166 578.00
IUUC-Oga-088131 Otolemur garnettii 99.37 0.00e+00 658.00
IUUC-Oar-090403 Ovis aries 99.37 0.00e+00 658.00
IUUC-Ptr-091191 Pan troglodytes 99.37 0.00e+00 658.00
IUUC-Pan-092357 Papio anubis 99.37 0.00e+00 658.00
IUUC-Pma-094205 Petromyzon marinus 40.43 9.00e-49 186.00
IUUC-Ppa-095298 Physcomitrella patens 27.39 2.00e-13 70.90
IUUC-Pfo-097228 Poecilia formosa 89.94 2.00e-174 604.00
IUUC-Pab-098397 Pongo abelii 99.37 0.00e+00 658.00
IUUC-Pca-100512 Procavia capensis 77.73 1.00e-106 378.00
IUUC-Pva-102669 Pteropus vampyrus 98.11 0.00e+00 650.00
IUUC-Rno-105591 Rattus norvegicus 99.37 0.00e+00 657.00
IUUC-Sha-106755 Sarcophilus harrisii 99.06 0.00e+00 656.00
IUUC-Sit-110762 Setaria italica 28.99 3.00e-17 83.20
IUUC-Sbi-114785 Sorghum bicolor 28.99 2.00e-17 83.60
IUUC-Ssc-115855 Sus scrofa 99.37 0.00e+00 658.00
IUUC-Tgu-116574 Taeniopygia guttata 98.74 0.00e+00 654.00
IUUC-Tru-118561 Takifugu rubripes 89.94 7.00e-174 602.00
IUUC-Tsy-119067 Tarsius syrichta 86.48 1.00e-160 558.00
IUUC-Tni-120352 Tetraodon nigroviridis 89.94 1.00e-174 605.00
IUUC-Tae-123967 Triticum aestivum 28.57 2.00e-16 80.50
IUUC-Tme-127091 Tuber melanosporum 34.38 5.00e-05 40.80
IUUC-Ttr-129317 Tursiops truncatus 95.60 2.00e-174 604.00
IUUC-Vpa-130472 Vicugna pacos 99.37 0.00e+00 658.00
IUUC-Xtr-132653 Xenopus tropicalis 95.91 0.00e+00 639.00
IUUC-Xma-134170 Xiphophorus maculatus 89.62 3.00e-174 603.00
Created Date 25-Jun-2017

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