iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-057945

Ensembl Protein ID

AES71867

UniProt Accession

G7JA39; G7JA39_MEDTR

Genbank Protein ID

AES71867.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CM001219

Gene Name

MTR_3g083600

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_3g083600	AES71867	AES71867

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-82	279.2	232	1069

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflaf 98
           G+ NlgNtC++NS++Q L+++++lr+++l+     +++       g+l++sl+klf+e    ++ k+ ++pr+++ ++++++++f+gy+q+D++E+l++
   Q: 232  GMVNLGNTCFFNSIMQNLLAMNKLRDNFLR-----VDAF-----VGPLISSLKKLFTETNpeSGFKNIINPRSFFGCVCSKSPQFRGYQQHDSHELLRC 320
           9*****************************.....5443.....589************999999********************************** PP
   S: 99   lldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke............ 185
           lld+l++e           + +    ++++ + +++ +++k+l++ lF+gq++s++ c+ec+++s+ +epfldlslpvp k+    +            
   Q: 321  LLDGLSTEE----------LAG----RKQNGSLKRDGTSSKTLVDALFGGQISSTVCCNECGHSSTVYEPFLDLSLPVPTKKPPPRKaqpaprtrktkp 405
           ******998..........222....22334567899******************************************9996644499********** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 406  ppkkgaksrvkvnrdvdplpvqnipsqsscldqsvtsgagelvissgvstvlgseeisseakvnrdddplptqnvpsqssshesscpdqsvtsvagelv 504
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 505  assgvstvlgseeisseankedlspsnlvtvvesqqiqgfdsvatktsdssdafawldfveaetneedlsppnlvtvgesqqmqgldsvanktsdssdd 603
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 604  fpwldyveaettideyasisqkedalevqdsenkderltafpeqgscetsgpvcflkedqnqrpdfsssneredevplqvqnsevlllpykeesssagd 702
           *************************************************************************************************** PP
   S: 186  ........................................................................slqdcLesftkeeelegenkyycekck 212
                                                                                   s+++cL++f k+e l +en+++ce+c 
   Q: 703  itgidggdsssvlgggpeesefdafgglfnepevvagpaprpsssgdveagiiirnisesdpdevddtdspvSVESCLAHFIKPELLSDENAWHCENCS 801
           *************************************************************************************************** PP
   S: 213  ................................................................................................... 212
                                                                                                              
   Q: 802  kilqrqkkkakeqektlsdgnasgshdeswhaskacsfkvsstgnediendkniessvshvqhgtelengqkdelrncelqssslhqpnneescdnsav 900
           ***********************************************************************************9999999999999999 PP
   S: 213  ....................................kkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkek 275
                                                +++a+k++ + + P+vL++hLkRfs + + ++ +k+n +v+f +++dl+p++  ++ ++ e+
   Q: 901  dssitgnvqqdapmlnnddndseecsgketglesirVNRDATKRVLIYRAPPVLTIHLKRFSQDAR-GRLSKLNGHVNFRETMDLRPYMDPRCINE-EE 997
           9999999999999999999988888888888887777777*********************77665.8899********************99998.5* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvkn............ekgk...WllfdDskVtevkeeevleetgstaYvlfYkr 337
           +kY+L++vv HsG++++GHYvayv+             +  +   W++ +D +V++v+ +evl+   ++aY+lfY+r
   Q: 998  YKYQLVGVVEHSGTMRGGHYVAYVRGgqrnrekvdnkeN--EsstWYHASDAYVRQVSLDEVLR---CEAYILFYER 1069
           **************************8888888876541..1567*******************...********98 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MAKKIKKRGR SSVKEKAVII DSSPKIVTES CNPPTTESVG EEVSVAKETN PCPHLVKGIQ 60
LDILSGKVES SAPIRCEGCR EGAADRRGGK GKGKHGKKKG GADSKSDSKS IWVCLECGQY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGATTGGAT CGGGCAGTGT GACCCGACTG GACTGGTAAC ACAAACCAAC CTTGCACGTC 60
TCTCTCTCCA CCCGAGAGAG GGAGAGAGCT CATCCACCAC CATCCGCCGC ATCTTTCAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mtr:MTR_3g083600

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	39.32	9.00e-57	214.00
IUUC-Aml-001931	Ailuropoda melanoleuca	31.25	3.00e-33	136.00
IUUC-Atr-003015	Amborella trichopoda	42.56	1.00e-78	288.00
IUUC-Apl-004145	Anas platyrhynchos	29.44	8.00e-36	145.00
IUUC-Aca-004314	Anolis carolinensis	28.57	3.00e-31	130.00
IUUC-Aly-005494	Arabidopsis lyrata	56.68	5.00e-101	362.00
IUUC-Ath-007211	Arabidopsis thaliana	55.31	9.00e-101	361.00
IUUC-Ame-011659	Astyanax mexicanus	35.16	1.00e-27	118.00
IUUC-Bta-013362	Bos taurus	31.16	4.00e-32	132.00
IUUC-Bdi-014624	Brachypodium distachyon	37.27	8.00e-53	201.00
IUUC-Bol-015853	Brassica oleracea	51.46	6.00e-90	325.00
IUUC-Bra-017226	Brassica rapa	52.49	3.00e-102	365.00
IUUC-Cja-019144	Callithrix jacchus	30.96	2.00e-32	133.00
IUUC-Cfa-020051	Canis familiaris	31.27	1.00e-32	134.00
IUUC-Cpo-021886	Cavia porcellus	30.36	2.00e-35	144.00
IUUC-Csa-023910	Chlorocebus sabaeus	31.79	2.00e-34	140.00
IUUC-Cho-024315	Choloepus hoffmanni	42.98	3.00e-19	89.70
IUUC-Cin-025775	Ciona intestinalis	37.86	9.00e-20	88.60
IUUC-Csv-026075	Ciona savignyi	37.24	4.00e-21	95.50
IUUC-Cme-027348	Cyanidioschyzon merolae	36.30	8.00e-20	91.70
IUUC-Dre-028388	Danio rerio	28.29	1.00e-33	137.00
IUUC-Dno-029409	Dasypus novemcinctus	30.33	2.00e-32	134.00
IUUC-Dor-030443	Dipodomys ordii	42.76	2.00e-27	117.00
IUUC-Dse-031252	Dothistroma septosporum	28.91	2.00e-12	67.00
IUUC-Dme-031870	Drosophila melanogaster	29.61	1.00e-15	78.60
IUUC-Ete-032807	Echinops telfairi	44.30	1.00e-28	120.00
IUUC-Eca-033479	Equus caballus	31.52	1.00e-32	134.00
IUUC-Eeu-034835	Erinaceus europaeus	43.42	2.00e-27	117.00
IUUC-Fca-036320	Felis catus	30.95	2.00e-32	133.00
IUUC-Fal-037199	Ficedula albicollis	32.86	3.00e-37	149.00
IUUC-Gmo-039480	Gadus morhua	28.26	5.00e-33	135.00
IUUC-Gga-040527	Gallus gallus	29.17	7.00e-33	135.00
IUUC-Gac-042343	Gasterosteus aculeatus	28.99	1.00e-34	140.00
IUUC-Gma-044402	Glycine max	65.66	0.00e+00	1267.00
IUUC-Ggo-045402	Gorilla gorilla	31.58	4.00e-34	139.00
IUUC-Hsa-046430	Homo sapiens	31.27	8.00e-34	138.00
IUUC-Hvu-047146	Hordeum vulgare	38.60	2.00e-52	201.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	30.24	3.00e-32	133.00
IUUC-Lch-050536	Latimeria chalumnae	29.05	3.00e-34	139.00
IUUC-Lpe-050703	Leersia perrieri	40.15	6.00e-53	202.00
IUUC-Loc-051814	Lepisosteus oculatus	28.43	4.00e-34	139.00
IUUC-Laf-053732	Loxodonta africana	29.12	1.00e-34	141.00
IUUC-Mcc-055491	Macaca mulatta	31.58	1.00e-34	140.00
IUUC-Meu-055967	Macropus eugenii	26.02	5.00e-26	112.00
IUUC-Mga-059551	Meleagris gallopavo	28.53	8.00e-34	138.00
IUUC-Mvi-060391	Microbotryum violaceum	32.04	3.00e-14	73.90
IUUC-Mmr-061747	Microcebus murinus	30.93	1.00e-31	130.00
IUUC-Mdo-062220	Monodelphis domestica	27.84	3.00e-33	136.00
IUUC-Mmu-063582	Mus musculus	28.87	5.00e-33	135.00
IUUC-Mac-064941	Musa acuminata	41.96	1.00e-72	266.00
IUUC-Mpu-066339	Mustela putorius furo	31.02	1.00e-32	134.00
IUUC-Mlu-067511	Myotis lucifugus	29.62	1.00e-33	137.00
IUUC-Nle-069828	Nomascus leucogenys	30.96	9.00e-33	134.00
IUUC-Opr-070969	Ochotona princeps	37.37	3.00e-27	116.00
IUUC-Ont-071786	Oreochromis niloticus	31.23	1.00e-32	134.00
IUUC-Oan-073656	Ornithorhynchus anatinus	31.48	1.00e-34	141.00
IUUC-Ocu-074323	Oryctolagus cuniculus	31.17	6.00e-33	135.00
IUUC-Oba-075094	Oryza barthii	39.34	6.00e-54	205.00
IUUC-Obr-076743	Oryza brachyantha	39.43	5.00e-51	196.00
IUUC-Ogl-077739	Oryza glaberrima	39.34	4.00e-54	206.00
IUUC-Ogu-078851	Oryza glumaepatula	39.42	7.00e-54	205.00
IUUC-Oin-079402	Oryza indica	39.42	6.00e-54	205.00
IUUC-Olo-080431	Oryza longistaminata	39.42	6.00e-54	205.00
IUUC-Ome-081580	Oryza meridionalis	39.78	1.00e-53	204.00
IUUC-Oni-082644	Oryza nivara	39.42	6.00e-54	205.00
IUUC-Opu-083452	Oryza punctata	39.34	5.00e-54	206.00
IUUC-Oru-084546	Oryza rufipogon	39.42	7.00e-54	205.00
IUUC-Osa-085858	Oryza sativa	39.42	7.00e-54	205.00
IUUC-Ola-086795	Oryzias latipes	30.56	1.00e-31	131.00
IUUC-Oga-088713	Otolemur garnettii	31.44	3.00e-32	133.00
IUUC-Oar-089971	Ovis aries	30.82	1.00e-32	134.00
IUUC-Ptr-091358	Pan troglodytes	31.58	3.00e-34	139.00
IUUC-Pan-092023	Papio anubis	31.58	2.00e-34	140.00
IUUC-Psi-093256	Pelodiscus sinensis	31.71	5.00e-33	135.00
IUUC-Ppa-095622	Physcomitrella patens	33.41	5.00e-48	186.00
IUUC-Pfo-097202	Poecilia formosa	29.79	5.00e-33	135.00
IUUC-Pab-098539	Pongo abelii	31.17	9.00e-34	138.00
IUUC-Pop-099588	Populus trichocarpa	44.66	0.00e+00	714.00
IUUC-Pca-101069	Procavia capensis	43.42	2.00e-27	117.00
IUUC-Ppe-101794	Prunus persica	66.77	3.00e-125	442.00
IUUC-Pva-103092	Pteropus vampyrus	43.42	1.00e-27	117.00
IUUC-Rno-105237	Rattus norvegicus	28.22	6.00e-33	135.00
IUUC-Sha-107022	Sarcophilus harrisii	29.28	4.00e-33	135.00
IUUC-Sja-107712	Schizosaccharomyces japonicus	33.56	6.00e-17	82.40
IUUC-Spo-108149	Schizosaccharomyces pombe	38.10	6.00e-22	99.00
IUUC-Smo-108723	Selaginella moellendorffii	52.05	2.00e-42	165.00
IUUC-Sit-110283	Setaria italica	40.91	6.00e-53	202.00
IUUC-Sly-111487	Solanum lycopersicum	53.83	1.00e-117	417.00
IUUC-Stu-112820	Solanum tuberosum	43.66	0.00e+00	664.00
IUUC-Sar-113530	Sorex araneus	31.21	3.00e-34	139.00
IUUC-Sbi-113785	Sorghum bicolor	36.51	1.00e-46	181.00
IUUC-Ssc-116091	Sus scrofa	30.21	1.00e-31	131.00
IUUC-Tgu-117478	Taeniopygia guttata	31.23	4.00e-36	145.00
IUUC-Tru-118640	Takifugu rubripes	27.78	9.00e-36	144.00
IUUC-Tsy-118869	Tarsius syrichta	30.67	9.00e-31	128.00
IUUC-Tni-120015	Tetraodon nigroviridis	27.80	5.00e-32	132.00
IUUC-Tca-121701	Theobroma cacao	48.07	0.00e+00	830.00
IUUC-Tae-125351	Triticum aestivum	38.97	5.00e-50	192.00
IUUC-Tur-126788	Triticum urartu	38.24	4.00e-49	189.00
IUUC-Tbe-128041	Tupaia belangeri	35.58	1.00e-26	114.00
IUUC-Ttr-128271	Tursiops truncatus	30.84	5.00e-32	132.00
IUUC-Vpa-130674	Vicugna pacos	31.21	2.00e-31	130.00
IUUC-Vvi-131230	Vitis vinifera	72.88	2.00e-24	102.00
IUUC-Xtr-131869	Xenopus tropicalis	27.60	1.00e-33	137.00
IUUC-Xma-134195	Xiphophorus maculatus	30.59	6.00e-33	135.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence