iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073738

UUCD1 version

UUC-OrA-00300

Ensembl Protein ID

ENSOANP00000011835.1

UniProt Accession

F6XTW2; F6XTW2_ORNAN

Protein Name

Uncharacterized protein

Gene Name

RNF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000007432.2	ENSOANT00000011837.2	ENSOANP00000011835.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.80e-54	183.9	210	423

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e +++ eC+h++C++Clk+y+e++i++gqv++++cp+++c++ +++ ++ke lv eel++ry++lll+++++ +a++ +
   Q: 210  CHICFCEKLGRESMYFSECRHVYCRACLKDYFEIQIRDGQVHCLNCPEPKCSSVATPGQVKE-LVAEELFARYDRLLLQSSLDLMADVVY 298
           **************************************************************.699************************ PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+pdC+++v++e+     ++  c++c+ +fC+ Ck ++H  + Ck ++ekl + ++e+                        ee+eske
   Q: 299  CPRPDCQTPVMQEPG---CTMGiCSSCNYAFCTLCKMTYHGVSPCKVTAEKLIDLRNEYleadeankrfleqrygkrviqkalEEMESKE 385
           *************95...33337*********************************999******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C + iek +gCn+mtC+ C+ +fCw+C
   Q: 386  WLEKNSKSCPCCGTHIEKLDGCNKMTCTGCMRYFCWIC 423
           ************************************** PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MSSEDREAQE DELLALASIY DEDEFKKAES TQGGETRICL ELPQNFKIFV SGNSTEGPQN 60
GGFEYTICFL PPLVLNFEFP PDYPSTSPPA FTLSGKWLSR AQLTALCKHL DNLWEENRGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGTTAAAT GTCGTCAGAA GACCGAGAAG CCCAGGAGGA TGAATTGCTG GCCTTGGCGA 60
GTATTTATGA TGAAGACGAA TTTAAAAAGG CAGAGTCTAC CCAAGGTGGA GAAACCAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0007165--P:signal transduction

KEGG

oaa:100078857

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	30.48	2.00e-57	216.00
IUUC-Aml-001458	Ailuropoda melanoleuca	82.98	0.00e+00	776.00
IUUC-Atr-002560	Amborella trichopoda	29.38	4.00e-51	195.00
IUUC-Apl-003680	Anas platyrhynchos	83.16	0.00e+00	818.00
IUUC-Aca-005000	Anolis carolinensis	72.84	0.00e+00	691.00
IUUC-Aly-006288	Arabidopsis lyrata	29.73	1.00e-57	217.00
IUUC-Ath-006719	Arabidopsis thaliana	29.91	2.00e-57	216.00
IUUC-Acl-008213	Aspergillus clavatus	24.04	3.00e-33	135.00
IUUC-Afl-008433	Aspergillus flavus	24.77	1.00e-33	137.00
IUUC-Afu-008772	Aspergillus fumigatus	24.38	2.00e-35	142.00
IUUC-Ani-009249	Aspergillus nidulans	25.41	2.00e-33	136.00
IUUC-Ang-009757	Aspergillus niger	28.33	8.00e-40	157.00
IUUC-Aor-009963	Aspergillus oryzae	24.61	6.00e-33	135.00
IUUC-Ate-010460	Aspergillus terreus	24.31	6.00e-34	138.00
IUUC-Ame-011312	Astyanax mexicanus	59.51	2.00e-154	538.00
IUUC-Bgr-012052	Blumeria graminis	22.71	1.00e-31	130.00
IUUC-Bta-013529	Bos taurus	82.49	0.00e+00	782.00
IUUC-Bci-013729	Botrytis cinerea	24.11	3.00e-31	129.00
IUUC-Bdi-014940	Brachypodium distachyon	32.52	1.00e-54	207.00
IUUC-Bra-016998	Brassica rapa	29.05	5.00e-55	208.00
IUUC-Cel-018547	Caenorhabditis elegans	32.97	2.00e-63	235.00
IUUC-Cja-019791	Callithrix jacchus	81.22	0.00e+00	769.00
IUUC-Cfa-020403	Canis familiaris	82.70	0.00e+00	781.00
IUUC-Cpo-022229	Cavia porcellus	79.83	0.00e+00	745.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	33.02	1.00e-28	118.00
IUUC-Csa-024115	Chlorocebus sabaeus	82.07	0.00e+00	772.00
IUUC-Cho-024911	Choloepus hoffmanni	82.91	0.00e+00	780.00
IUUC-Cin-025578	Ciona intestinalis	41.47	4.00e-101	360.00
IUUC-Csv-026355	Ciona savignyi	40.73	1.00e-87	315.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	19.89	3.00e-27	116.00
IUUC-Cne-026782	Cryptococcus neoformans	23.41	4.00e-33	135.00
IUUC-Dre-027380	Danio rerio	59.17	3.00e-163	567.00
IUUC-Dno-029640	Dasypus novemcinctus	82.29	0.00e+00	782.00
IUUC-Dor-030681	Dipodomys ordii	82.49	0.00e+00	780.00
IUUC-Dse-031208	Dothistroma septosporum	24.19	3.00e-35	142.00
IUUC-Ete-033122	Echinops telfairi	55.92	1.00e-136	479.00
IUUC-Eca-033755	Equus caballus	81.62	0.00e+00	750.00
IUUC-Eeu-035034	Erinaceus europaeus	89.08	2.00e-62	233.00
IUUC-Fca-036461	Felis catus	83.12	0.00e+00	785.00
IUUC-Fal-037516	Ficedula albicollis	82.95	0.00e+00	821.00
IUUC-Fso-038307	Fusarium solani	21.91	3.00e-27	116.00
IUUC-Gmo-039563	Gadus morhua	58.50	3.00e-158	550.00
IUUC-Ggr-039920	Gaeumannomyces graminis	21.28	4.00e-24	106.00
IUUC-Gga-040331	Gallus gallus	83.80	0.00e+00	818.00
IUUC-Gac-042164	Gasterosteus aculeatus	58.82	3.00e-168	584.00
IUUC-Gma-044080	Glycine max	30.97	2.00e-61	229.00
IUUC-Ggo-045257	Gorilla gorilla	82.28	0.00e+00	775.00
IUUC-Hsa-046887	Homo sapiens	82.61	0.00e+00	751.00
IUUC-Hvu-047317	Hordeum vulgare	29.07	3.00e-48	186.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	82.07	0.00e+00	778.00
IUUC-Lch-050155	Latimeria chalumnae	65.79	5.00e-175	606.00
IUUC-Lpe-051669	Leersia perrieri	27.47	1.00e-39	157.00
IUUC-Loc-051779	Lepisosteus oculatus	61.56	4.00e-163	566.00
IUUC-Lma-052969	Leptosphaeria maculans	24.72	1.00e-32	133.00
IUUC-Laf-053488	Loxodonta africana	80.84	0.00e+00	781.00
IUUC-Mcc-054701	Macaca mulatta	82.17	0.00e+00	749.00
IUUC-Meu-056577	Macropus eugenii	77.09	4.00e-118	417.00
IUUC-Mor-057157	Magnaporthe oryzae	21.74	1.00e-28	120.00
IUUC-Mpo-057518	Magnaporthe poae	21.51	6.00e-28	118.00
IUUC-Mtr-058125	Medicago truncatula	29.69	2.00e-52	199.00
IUUC-Mga-059906	Meleagris gallopavo	83.58	0.00e+00	815.00
IUUC-Mvi-060374	Microbotryum violaceum	32.00	6.00e-33	134.00
IUUC-Mmr-061786	Microcebus murinus	82.91	0.00e+00	778.00
IUUC-Mdo-062453	Monodelphis domestica	88.38	0.00e+00	820.00
IUUC-Mmu-063521	Mus musculus	78.76	0.00e+00	721.00
IUUC-Mac-065119	Musa acuminata	27.94	8.00e-42	164.00
IUUC-Mpu-066274	Mustela putorius furo	83.54	0.00e+00	785.00
IUUC-Mlu-067202	Myotis lucifugus	79.57	0.00e+00	717.00
IUUC-Nfi-068564	Neosartorya fischeri	24.16	4.00e-34	139.00
IUUC-Ncr-068823	Neurospora crassa	23.92	4.00e-34	139.00
IUUC-Nle-068987	Nomascus leucogenys	82.65	0.00e+00	753.00
IUUC-Opr-070453	Ochotona princeps	80.59	0.00e+00	764.00
IUUC-Ont-072611	Oreochromis niloticus	58.61	1.00e-168	585.00
IUUC-Ocu-074396	Oryctolagus cuniculus	81.86	0.00e+00	772.00
IUUC-Oba-075472	Oryza barthii	31.31	2.00e-49	190.00
IUUC-Obr-076277	Oryza brachyantha	31.03	3.00e-52	199.00
IUUC-Ogl-077046	Oryza glaberrima	30.98	4.00e-48	185.00
IUUC-Ogu-078634	Oryza glumaepatula	31.31	9.00e-50	191.00
IUUC-Oin-080080	Oryza indica	29.32	3.00e-50	192.00
IUUC-Olo-080828	Oryza longistaminata	29.05	3.00e-47	183.00
IUUC-Ome-081387	Oryza meridionalis	27.78	3.00e-52	198.00
IUUC-Oni-082934	Oryza nivara	31.31	9.00e-50	191.00
IUUC-Opu-083719	Oryza punctata	29.06	7.00e-47	181.00
IUUC-Oru-084518	Oryza rufipogon	31.31	9.00e-50	191.00
IUUC-Ola-087312	Oryzias latipes	59.50	1.00e-165	575.00
IUUC-Olu-087661	Ostreococcus lucimarinus	29.48	7.00e-54	204.00
IUUC-Oga-089129	Otolemur garnettii	83.30	0.00e+00	781.00
IUUC-Oar-089839	Ovis aries	82.28	0.00e+00	781.00
IUUC-Ptr-091626	Pan troglodytes	82.61	0.00e+00	752.00
IUUC-Pan-092798	Papio anubis	82.17	0.00e+00	749.00
IUUC-Psi-093253	Pelodiscus sinensis	82.03	0.00e+00	796.00
IUUC-Pma-094512	Petromyzon marinus	55.91	2.00e-155	541.00
IUUC-Pno-094937	Phaeosphaeria nodorum	22.65	6.00e-32	131.00
IUUC-Ppa-095211	Physcomitrella patens	30.67	7.00e-60	224.00
IUUC-Pfo-097049	Poecilia formosa	54.53	5.00e-150	523.00
IUUC-Pab-097911	Pongo abelii	82.61	0.00e+00	752.00
IUUC-Pop-099841	Populus trichocarpa	30.84	5.00e-55	208.00
IUUC-Pca-100814	Procavia capensis	64.69	5.00e-163	566.00
IUUC-Ppe-101972	Prunus persica	30.14	4.00e-53	201.00
IUUC-Pva-103038	Pteropus vampyrus	81.43	0.00e+00	765.00
IUUC-Pgr-103277	Puccinia graminis	29.31	4.00e-42	165.00
IUUC-Ptt-103855	Puccinia triticina	26.63	2.00e-38	152.00
IUUC-Pte-104113	Pyrenophora teres	23.82	3.00e-29	122.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	23.67	8.00e-31	127.00
IUUC-Rno-106003	Rattus norvegicus	78.79	0.00e+00	731.00
IUUC-Sce-106287	Saccharomyces cerevisiae	28.19	1.00e-23	103.00
IUUC-Sha-106652	Sarcophilus harrisii	89.15	0.00e+00	833.00
IUUC-Spo-108167	Schizosaccharomyces pombe	30.30	1.00e-57	216.00
IUUC-Ssl-108396	Sclerotinia sclerotiorum	24.89	4.00e-09	56.20
IUUC-Smo-109393	Selaginella moellendorffii	31.29	3.00e-54	205.00
IUUC-Sit-110529	Setaria italica	31.32	6.00e-50	191.00
IUUC-Sly-111829	Solanum lycopersicum	30.16	3.00e-56	212.00
IUUC-Stu-112811	Solanum tuberosum	30.16	1.00e-56	213.00
IUUC-Sar-113259	Sorex araneus	76.62	5.00e-113	400.00
IUUC-Sbi-114591	Sorghum bicolor	31.61	2.00e-41	163.00
IUUC-Sre-115227	Sporisorium reilianum	25.10	1.00e-41	164.00
IUUC-Ssc-115293	Sus scrofa	82.28	0.00e+00	777.00
IUUC-Tgu-117335	Taeniopygia guttata	83.90	0.00e+00	820.00
IUUC-Tru-118458	Takifugu rubripes	57.56	2.00e-164	571.00
IUUC-Tsy-119475	Tarsius syrichta	74.26	0.00e+00	667.00
IUUC-Tni-119827	Tetraodon nigroviridis	57.93	1.00e-162	565.00
IUUC-Tca-121023	Theobroma cacao	31.17	1.00e-56	213.00
IUUC-Tre-121965	Trichoderma reesei	22.22	9.00e-32	130.00
IUUC-Tvi-122564	Trichoderma virens	20.81	4.00e-28	119.00
IUUC-Tae-124793	Triticum aestivum	31.17	8.00e-46	177.00
IUUC-Tur-126258	Triticum urartu	29.44	5.00e-48	184.00
IUUC-Tbe-127227	Tupaia belangeri	69.90	8.00e-73	266.00
IUUC-Ttr-128984	Tursiops truncatus	62.00	3.00e-159	554.00
IUUC-Uma-129565	Ustilago maydis	24.19	4.00e-35	142.00
IUUC-Vpa-130301	Vicugna pacos	82.49	0.00e+00	780.00
IUUC-Vvi-131244	Vitis vinifera	31.14	7.00e-58	218.00
IUUC-Xtr-132880	Xenopus tropicalis	59.54	2.00e-165	575.00
IUUC-Xma-134055	Xiphophorus maculatus	60.04	2.00e-169	587.00
IUUC-Yli-134342	Yarrowia lipolytica	30.18	3.00e-50	191.00
IUUC-Zma-135021	Zea mays	30.56	5.00e-44	171.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence