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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063266
Ensembl Protein ID ENSMUSP00000102546.1
UniProt Accession Q80TZ3; B1B0B9; Q6P2K9; Q8C7L9; AUXI_MOUSE
Genbank Protein ID BAC65575.1; BAC33992.1; BAE28000.1; BAE28039.1; BAE37443.1; CAM16148.1; AAH60734.1; AAH64460.1
Protein Name Putative tyrosine-protein phosphatase auxilin; DnaJ homolog subfamily C member 6
Genbank Nucleotide ID AK122293; AK049935; AK147570; AK147637; AK163657; BX323551; BC060734; BC064460
Gene Name Dnajc6; Kiaa0473
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000028528.16 ENSMUST00000038207.11 ENSMUSP00000044251.5
ENSMUSG00000028528.16 ENSMUST00000106933.1 ENSMUSP00000102546.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitecircBasemiRTarBasemicroRNA
TRANSFACRepTarRAID2
Protein-protein Interaction
IIDHINTMentha
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UBA 39.13 1.00e-10 63.90 IUUC-Sce-106221
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons.
 Recruits HSPA8/HSC70 to clathrin-coated vesicles and promotes uncoating of clathrin-coated vesicles. Plays a role in clathrin-mediated endocytosis in neurons.
Protein Sequence
(Fasta)
MSLLGSYRKK TSSDGYESLQ LVDSHGDSSA RGAAAGTQRA TAGAVRSPAR QPPHRASTTD 60
SSGASSPDME PSYGGGLFDM VKGGAGRLFS NLKDNLKDTL KDTSSRVIQS VSSYTKGDLD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063266|UBD,UBA|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGCGCACCA ATGGGCGCGA CCGAGGCCGG AGGCACTAAG AGCCGGAGGC TGCTGTCGGT 60
GCTGCGGCGG TGGCGCGCGG ATCAGCGGCT GCGGAGGATG CGATCGGCTC TCCGGGGTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063266|UBD,UBA|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0597--Phosphoprotein
KW-0904--Protein phosphatase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0729--SH3-binding
Interpro

IPR000008--C2_dom
IPR001623--DnaJ_domain
IPR029021--Prot-tyrosine_phosphatase-like
IPR014020--Tensin_C2-dom
IPR029023--Tensin_phosphatase
PROSITE

PS51182--C2_TENSIN
PS50076--DNAJ_2
PS51181--PPASE_TENSIN
Pfam

PF10409--PTEN_C2
SMART

SM00271--DnaJ
SM01326--PTEN_C2
Gene Ontology

GO:0005622--C:intracellular
GO:0014069--C:postsynaptic density
GO:0045202--C:synapse
GO:0031982--C:vesicle
GO:0004725--F:protein tyrosine phosphatase activity
GO:0072318--P:clathrin coat disassembly
GO:2000369--P:regulation of clathrin-dependent endocytosis
GO:0016191--P:synaptic vesicle uncoating
KEGG mmu:72685
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001602 Ailuropoda melanoleuca 95.26 6.00e-101 359.00
IUUC-Atr-002789 Amborella trichopoda 46.75 7.00e-15 76.30
IUUC-Apl-003319 Anas platyrhynchos 73.97 0.00e+00 1213.00
IUUC-Aca-004679 Anolis carolinensis 71.70 0.00e+00 1200.00
IUUC-Aly-006371 Arabidopsis lyrata 41.12 3.00e-17 84.00
IUUC-Ath-007246 Arabidopsis thaliana 34.62 1.00e-18 88.20
IUUC-Ame-011836 Astyanax mexicanus 56.85 0.00e+00 856.00
IUUC-Bgr-012104 Blumeria graminis 31.30 1.00e-12 68.60
IUUC-Bta-012737 Bos taurus 93.18 0.00e+00 1533.00
IUUC-Bci-013716 Botrytis cinerea 37.38 5.00e-15 76.60
IUUC-Bol-016505 Brassica oleracea 33.97 1.00e-17 84.70
IUUC-Bra-017031 Brassica rapa 33.97 7.00e-18 85.50
IUUC-Cja-019196 Callithrix jacchus 91.96 0.00e+00 1584.00
IUUC-Cfa-020198 Canis familiaris 92.32 0.00e+00 1505.00
IUUC-Cpo-022425 Cavia porcellus 87.65 0.00e+00 1429.00
IUUC-Cre-022715 Chlamydomonas reinhardtii 43.33 7.00e-13 67.80
IUUC-Csa-023487 Chlorocebus sabaeus 93.41 0.00e+00 1511.00
IUUC-Cho-024924 Choloepus hoffmanni 85.78 0.00e+00 905.00
IUUC-Cin-025341 Ciona intestinalis 35.99 1.00e-159 556.00
IUUC-Csv-026368 Ciona savignyi 38.87 8.00e-58 218.00
IUUC-Cgl-026441 Colletotrichum gloeosporioides 36.67 1.00e-12 69.30
IUUC-Cme-027261 Cyanidioschyzon merolae 37.18 4.00e-09 57.00
IUUC-Dre-027719 Danio rerio 58.36 0.00e+00 883.00
IUUC-Dno-029249 Dasypus novemcinctus 86.21 0.00e+00 1467.00
IUUC-Dor-030705 Dipodomys ordii 93.93 0.00e+00 1503.00
IUUC-Dse-031381 Dothistroma septosporum 43.82 2.00e-14 75.10
IUUC-Ete-032360 Echinops telfairi 89.48 0.00e+00 889.00
IUUC-Eca-033503 Equus caballus 92.73 0.00e+00 1499.00
IUUC-Fox-038054 Fusarium oxysporum 37.50 2.00e-12 68.60
IUUC-Fso-038394 Fusarium solani 38.64 4.00e-13 70.50
IUUC-Gmo-038798 Gadus morhua 66.58 1.00e-176 613.00
IUUC-Ggr-040006 Gaeumannomyces graminis 37.23 4.00e-14 73.90
IUUC-Gga-040208 Gallus gallus 75.33 0.00e+00 1197.00
IUUC-Gac-041725 Gasterosteus aculeatus 62.53 5.00e-178 618.00
IUUC-Ggo-044959 Gorilla gorilla 93.94 0.00e+00 1515.00
IUUC-Hsa-046253 Homo sapiens 92.78 0.00e+00 1587.00
IUUC-Itr-048009 Ictidomys tridecemlineatus 86.48 0.00e+00 1417.00
IUUC-Lch-049852 Latimeria chalumnae 63.95 0.00e+00 1127.00
IUUC-Loc-052500 Lepisosteus oculatus 62.12 0.00e+00 1015.00
IUUC-Laf-053442 Loxodonta africana 88.11 0.00e+00 1412.00
IUUC-Mcc-055357 Macaca mulatta 93.81 0.00e+00 1508.00
IUUC-Meu-055902 Macropus eugenii 78.23 2.00e-175 609.00
IUUC-Mor-057010 Magnaporthe oryzae 37.89 1.00e-13 72.40
IUUC-Mpo-057447 Magnaporthe poae 38.30 2.00e-14 74.30
IUUC-Mtr-058569 Medicago truncatula 38.33 5.00e-17 83.20
IUUC-Mla-059090 Melampsora laricipopulina 39.13 1.00e-15 78.60
IUUC-Mga-059288 Meleagris gallopavo 73.36 0.00e+00 1192.00
IUUC-Mvi-060375 Microbotryum violaceum 45.35 8.00e-15 76.30
IUUC-Mmr-060617 Microcebus murinus 93.29 0.00e+00 1470.00
IUUC-Mdo-062466 Monodelphis domestica 72.85 0.00e+00 952.00
IUUC-Mac-065191 Musa acuminata 39.66 3.00e-18 87.40
IUUC-Mpu-066264 Mustela putorius furo 92.23 0.00e+00 1498.00
IUUC-Mlu-067016 Myotis lucifugus 93.05 0.00e+00 1557.00
IUUC-Ncr-068716 Neurospora crassa 40.00 1.00e-14 75.50
IUUC-Nle-069934 Nomascus leucogenys 92.68 0.00e+00 1587.00
IUUC-Ont-072687 Oreochromis niloticus 57.29 0.00e+00 875.00
IUUC-Ocu-074760 Oryctolagus cuniculus 87.14 0.00e+00 1362.00
IUUC-Olo-080973 Oryza longistaminata 46.51 2.00e-15 77.40
IUUC-Ola-086849 Oryzias latipes 57.34 0.00e+00 953.00
IUUC-Oga-088457 Otolemur garnettii 91.29 0.00e+00 1527.00
IUUC-Oar-089865 Ovis aries 91.61 0.00e+00 1471.00
IUUC-Ptr-091246 Pan troglodytes 92.58 0.00e+00 1583.00
IUUC-Pan-092688 Papio anubis 91.36 0.00e+00 1350.00
IUUC-Psi-093294 Pelodiscus sinensis 73.29 0.00e+00 1121.00
IUUC-Pma-094391 Petromyzon marinus 36.91 9.00e-112 397.00
IUUC-Ppa-095294 Physcomitrella patens 46.67 3.00e-16 81.30
IUUC-Pfo-096387 Poecilia formosa 54.41 0.00e+00 662.00
IUUC-Pab-097705 Pongo abelii 93.08 0.00e+00 1224.00
IUUC-Pop-098982 Populus trichocarpa 39.50 2.00e-18 87.40
IUUC-Pca-100190 Procavia capensis 86.60 0.00e+00 1177.00
IUUC-Ppe-101744 Prunus persica 39.50 8.00e-18 86.30
IUUC-Pva-102358 Pteropus vampyrus 90.29 0.00e+00 1526.00
IUUC-Rno-105923 Rattus norvegicus 92.65 0.00e+00 1607.00
IUUC-Sce-106221 Saccharomyces cerevisiae 39.13 3.00e-11 63.90
IUUC-Sha-106749 Sarcophilus harrisii 77.54 0.00e+00 1307.00
IUUC-Sja-107998 Schizosaccharomyces japonicus 41.28 3.00e-16 80.50
IUUC-Smo-108804 Selaginella moellendorffii 42.34 3.00e-16 81.30
IUUC-Sly-111651 Solanum lycopersicum 36.29 2.00e-17 85.10
IUUC-Sar-113634 Sorex araneus 87.06 0.00e+00 934.00
IUUC-Sre-115214 Sporisorium reilianum 39.08 2.00e-10 62.00
IUUC-Ssc-115636 Sus scrofa 92.78 0.00e+00 1531.00
IUUC-Tgu-116847 Taeniopygia guttata 73.11 0.00e+00 1145.00
IUUC-Tru-117730 Takifugu rubripes 56.45 0.00e+00 942.00
IUUC-Tsy-119269 Tarsius syrichta 83.90 0.00e+00 1027.00
IUUC-Tni-120061 Tetraodon nigroviridis 52.12 0.00e+00 676.00
IUUC-Tre-121980 Trichoderma reesei 32.23 1.00e-12 68.60
IUUC-Tvi-122538 Trichoderma virens 38.64 2.00e-13 71.60
IUUC-Tbe-128130 Tupaia belangeri 82.75 1.00e-176 613.00
IUUC-Vda-129786 Verticillium dahliae 31.71 3.00e-13 70.90
IUUC-Vpa-130526 Vicugna pacos 87.56 0.00e+00 1520.00
IUUC-Vvi-131028 Vitis vinifera 39.81 7.00e-16 79.00
IUUC-Xtr-132049 Xenopus tropicalis 65.67 0.00e+00 981.00
Created Date 25-Jun-2017

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