iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052645

Ensembl Protein ID

ENSLOCP00000016641.1

UniProt Accession

W5N7N2; W5N7N2_LEPOC

Genbank Protein ID

ENSLOCP00000016641

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01024878

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000013489.1	ENSLOCT00000016671.1	ENSLOCP00000016641.1
ENSLOCG00000013489.1	ENSLOCT00000016674.1	ENSLOCP00000016644.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.90e-135	451.1	576	905

Active Site

Position(s)	Description	Evidence
875	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR001569-1, ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpl 92
            lk+rl++ef++E+gld+gGv+re+++l+ske++np++glf+ys++d++tlq+np+sgl+n++hl++F+f+Gr+ g+a+++g+lld+++
   Q: 576  FLKARLWIEFENEKGLDYGGVAREWFFLISKEMFNPYYGLFEYSATDNYTLQINPNSGLCNEDHLSYFKFIGRVAGMAVYHGKLLDAFF 664
           5899************************************************************************************* PP
   S: 93   sksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyr 181
            ++fyk++l+k+++l+d+e+vd+e+++slk+i+en   d ++  ldl+f+++ee++g+++ +eL++gG +i Vtn+Nk+eY++lv+++r
   Q: 665  IRPFYKMMLQKPITLQDMESVDSEYFNSLKWILEN---DPTD--LDLRFTIDEELFGQIQYYELCSGGTDIVVTNKNKKEYIHLVMQWR 748
           *********************************99...6666..79999999************************************* PP
   S: 182  lkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTg 270
           + +++++q+ af+eGf+e+ipl+l+++F+e+elell+cG  ++dv+d++++tkyk+gy +++p+iqwFw+++  +++e+r ++LqFvTg
   Q: 749  FVNRVQKQMSAFKEGFYELIPLDLIKIFDENELELLMCGLGDVDVNDWRENTKYKNGYCATQPVIQWFWKTVLLMDAEKRIRLLQFVTG 837
           ***************************************************************************************** PP
   S: 271  ssrlPlgGfaelk....prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFe 334
           +srlP++Gfael     p+lf+i++++++d+lP+++TCfn+L+LP+Y+s e+l+ekL +Aie+++gF+
   Q: 838  TSRLPMNGFAELYgsngPQLFTIEQWGTPDKLPRAHTCFNRLDLPPYESFEELREKLHLAIENAQGFD 905
           *******************************************************************8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

TMASVAEVRG LQTDEEDSRI LRVKVIAGIG LAKKDILGAS DPYTRVSLYD PVNGELTSVQ 60
TKTIKKTLHP KWNEEFFFRV HPRKHRLLFE VFDENRLTRD DFLGQVDVPL HQIPMENPNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAAAAGACC GAAACGGGAG CGAATGTGTT TGAGTTGCGA CGATGGCTTC GGTGGCAGAA 60
GTGCGTGGTC TTCAGACCGA CGAGGTAACG ATTACATTGT GATTTTTATG AACGCCTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom

PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2

Pfam

PF00168--C2
PF00632--HECT
PF00397--WW

SMART

SM00239--C2
SM00119--HECTc
SM00456--WW

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001201	Ailuropoda melanoleuca	74.08	0.00e+00	1214.00
IUUC-Apl-003886	Anas platyrhynchos	68.81	0.00e+00	1296.00
IUUC-Ame-011138	Astyanax mexicanus	90.42	0.00e+00	891.00
IUUC-Bta-012453	Bos taurus	72.28	0.00e+00	1157.00
IUUC-Bci-013785	Botrytis cinerea	46.87	1.00e-153	536.00
IUUC-Cel-018564	Caenorhabditis elegans	53.25	3.00e-178	618.00
IUUC-Cfa-020258	Canis familiaris	74.82	0.00e+00	1172.00
IUUC-Cpo-021648	Cavia porcellus	73.04	0.00e+00	1328.00
IUUC-Csa-023334	Chlorocebus sabaeus	74.97	0.00e+00	1337.00
IUUC-Cin-025157	Ciona intestinalis	56.82	0.00e+00	995.00
IUUC-Csv-026098	Ciona savignyi	68.02	0.00e+00	633.00
IUUC-Cgl-026642	Colletotrichum gloeosporioides	47.52	3.00e-155	542.00
IUUC-Dre-027924	Danio rerio	76.04	0.00e+00	1179.00
IUUC-Dse-031241	Dothistroma septosporum	47.16	1.00e-156	546.00
IUUC-Dme-032166	Drosophila melanogaster	68.81	0.00e+00	715.00
IUUC-Ete-032409	Echinops telfairi	68.60	0.00e+00	947.00
IUUC-Eca-033441	Equus caballus	74.86	0.00e+00	1293.00
IUUC-Fca-036384	Felis catus	74.51	0.00e+00	1190.00
IUUC-Fal-037547	Ficedula albicollis	74.67	0.00e+00	1336.00
IUUC-Fox-037774	Fusarium oxysporum	48.32	2.00e-156	546.00
IUUC-Fso-038393	Fusarium solani	46.64	4.00e-153	535.00
IUUC-Gmo-039679	Gadus morhua	77.29	0.00e+00	1404.00
IUUC-Ggr-040107	Gaeumannomyces graminis	47.87	5.00e-155	541.00
IUUC-Gga-040524	Gallus gallus	74.48	0.00e+00	1337.00
IUUC-Gac-042607	Gasterosteus aculeatus	74.03	0.00e+00	1368.00
IUUC-Hsa-046479	Homo sapiens	74.57	0.00e+00	1213.00
IUUC-Itr-048383	Ictidomys tridecemlineatus	67.23	0.00e+00	963.00
IUUC-Kpa-049273	Komagataella pastoris	49.32	2.00e-161	562.00
IUUC-Lch-050445	Latimeria chalumnae	77.93	0.00e+00	1293.00
IUUC-Mcc-055585	Macaca mulatta	74.32	0.00e+00	1196.00
IUUC-Meu-056897	Macropus eugenii	86.41	6.00e-156	545.00
IUUC-Mor-057097	Magnaporthe oryzae	47.63	1.00e-154	540.00
IUUC-Mpo-057442	Magnaporthe poae	51.10	8.00e-145	508.00
IUUC-Mga-059362	Meleagris gallopavo	69.98	0.00e+00	1303.00
IUUC-Mmr-061061	Microcebus murinus	74.17	0.00e+00	1212.00
IUUC-Mpu-066567	Mustela putorius furo	74.81	0.00e+00	1358.00
IUUC-Mlu-068148	Myotis lucifugus	72.92	0.00e+00	1178.00
IUUC-Ncr-068918	Neurospora crassa	48.63	5.00e-158	551.00
IUUC-Nle-069225	Nomascus leucogenys	74.82	0.00e+00	1220.00
IUUC-Ont-071664	Oreochromis niloticus	72.94	0.00e+00	1329.00
IUUC-Oan-073019	Ornithorhynchus anatinus	76.25	0.00e+00	1296.00
IUUC-Ocu-074409	Oryctolagus cuniculus	74.32	0.00e+00	1215.00
IUUC-Oga-088241	Otolemur garnettii	67.28	0.00e+00	1041.00
IUUC-Oar-089797	Ovis aries	73.84	0.00e+00	1268.00
IUUC-Psi-093618	Pelodiscus sinensis	73.96	0.00e+00	1190.00
IUUC-Pno-095118	Phaeosphaeria nodorum	48.72	3.00e-159	555.00
IUUC-Pfo-097145	Poecilia formosa	73.40	0.00e+00	1311.00
IUUC-Pab-098394	Pongo abelii	75.00	0.00e+00	1329.00
IUUC-Pca-100568	Procavia capensis	66.17	0.00e+00	965.00
IUUC-Pgr-103620	Puccinia graminis	53.29	5.00e-146	511.00
IUUC-Pte-104016	Pyrenophora teres	48.82	3.00e-159	555.00
IUUC-Pyt-104550	Pyrenophora triticirepentis	48.82	3.00e-159	555.00
IUUC-Rno-106095	Rattus norvegicus	67.18	0.00e+00	1194.00
IUUC-Sha-107370	Sarcophilus harrisii	69.04	0.00e+00	1163.00
IUUC-Sja-107786	Schizosaccharomyces japonicus	51.07	1.00e-153	536.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	47.12	3.00e-155	542.00
IUUC-Tgu-117474	Taeniopygia guttata	75.14	0.00e+00	1356.00
IUUC-Tru-117675	Takifugu rubripes	72.23	0.00e+00	1319.00
IUUC-Tni-119993	Tetraodon nigroviridis	70.63	0.00e+00	1284.00
IUUC-Tre-122203	Trichoderma reesei	46.04	6.00e-154	538.00
IUUC-Tvi-122595	Trichoderma virens	46.54	3.00e-155	542.00
IUUC-Tbe-127408	Tupaia belangeri	68.48	0.00e+00	917.00
IUUC-Ttr-128437	Tursiops truncatus	65.68	0.00e+00	916.00
IUUC-Uma-129332	Ustilago maydis	52.99	2.00e-141	496.00
IUUC-Vda-129753	Verticillium dahliae	47.28	4.00e-153	535.00
IUUC-Vpa-130503	Vicugna pacos	64.42	0.00e+00	1029.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence