iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091968

Ensembl Protein ID

ENSPANP00000004326.1

UniProt Accession

A0A096MWR8; A0A096MWR8_PAPAN

Genbank Protein ID

ENSPANP00000004326

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01010399

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000011242.1	ENSPANT00000020108.1	ENSPANP00000004326.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-120	401.2	289	933
ULD/UDP/UBQ/UBQ_Other	2.60e-10	40.1	147	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS++QcLsn+p+l+e++l+ k++e+ln +np ++ ge++ks+++l++++w++k ++v+pr+++++++++a++fsgy+
   Q: 289  CGLSNLGNTCFMNSAIQCLSNTPPLTEYFLNdKYQEELNFDNPLGMRGEIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQ 377
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ec+++s++++pf++l
   Q: 378  QQDCQELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHLKRNDSIIVDIFHGLFKSTLVCPECAKISVTFDPFCYL 464
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 465  TLPLPMKKERTLEvylvrmdpltkpmqykvvvpkignildlctalsalsgipadkmivtdiynhrfhrifamdenlssimerddiyvfe 553
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 554  ininrtedtehviipvclrekfrhssythhtgsslfgqpflmavprnntedklynllllrmcryvkisteteetegslhcckdqningn 642
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 643  gpngiheegspsemetdepddessqdqelpsenensqsedsvggdndsenglctedtckgqltghkkrlftfqfnnlgntdinyikddt 731
           ***************************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  +l+dc+e ft++e+l  e+ +yc++ck++q+a+k
   Q: 732  rhirfddrqlrldersflaldwdpdlkkryfdenaaedfekhesveykppkkpfvKLKDCIELFTTKEKLGAEDPWYCPNCKEHQQATK 820
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.W 306
           kl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fp++ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+a++kn++++ W
   Q: 821  KLDLWSLPPVLVVHLKRFSYSR--YMRDKLDTLVDFPINdLDMSEFLINPNAG---PCRYNLIAVSNHYGGMGGGHYTAFAKNKDDGkW 904
           ******************9977..6999*********************9988...8**************************65555* PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++fdDs+V++ +e+++++   + aYvlfY+r+
   Q: 905  YYFDDSSVSTASEDQIVS---KAAYVLFYQRQ 933
           ******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++i+k ++ip + + rL++k      ++L ++d t++d gl++g+++++++k+++
   Q: 147  VVTRRFSKADTIDTIEKEIRKIFNIPdEKETRLWNKymsntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 217
           77899*********************999*****998875544569*********************9986 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MAEGGAADLD TQRSDIATLL KTSLRKGDTW YLVDSRWFKQ WKKYVGFDSW DKYQMGDQNV 60
YPGPIDNSGL LKDGDAQSLK EHLIDELDYI LLPTEGWNKL VSWYTLMEGQ EPIARKVVEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGAAG GCGGAGCGGC GGATCTGGAC ACCCAGCGGT CTGACATCGC GACGCTGCTC 60
AAAACCTCGC TCCGGAAAGG GGACACCTGG TAAGAGAAAG GGGTTGAGAT GCCTGCGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR013792--RNA3'P_cycl/enolpyr_Trfase_a/b
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0030509--P:BMP signaling pathway
GO:0035616--P:histone H2B conserved C-terminal lysine deubiquitination
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0060389--P:pathway-restricted SMAD protein phosphorylation
GO:0007179--P:transforming growth factor beta receptor signaling pathway
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001852	Ailuropoda melanoleuca	98.98	0.00e+00	1896.00
IUUC-Apl-003249	Anas platyrhynchos	95.17	0.00e+00	1724.00
IUUC-Aca-004261	Anolis carolinensis	93.54	0.00e+00	1739.00
IUUC-Aly-005644	Arabidopsis lyrata	36.08	5.00e-139	488.00
IUUC-Ath-006782	Arabidopsis thaliana	35.77	1.00e-138	487.00
IUUC-Acl-008284	Aspergillus clavatus	35.27	2.00e-55	211.00
IUUC-Afl-008507	Aspergillus flavus	43.30	1.00e-53	205.00
IUUC-Ame-010757	Astyanax mexicanus	78.65	0.00e+00	1260.00
IUUC-Bgr-012277	Blumeria graminis	42.40	2.00e-63	238.00
IUUC-Bta-013128	Bos taurus	95.82	0.00e+00	1862.00
IUUC-Bci-013993	Botrytis cinerea	42.81	5.00e-64	240.00
IUUC-Bdi-014013	Brachypodium distachyon	35.97	9.00e-150	524.00
IUUC-Bol-015570	Brassica oleracea	37.33	3.00e-154	538.00
IUUC-Bra-017029	Brassica rapa	36.15	3.00e-139	489.00
IUUC-Cja-019222	Callithrix jacchus	99.59	0.00e+00	1905.00
IUUC-Cfa-020035	Canis familiaris	98.98	0.00e+00	1894.00
IUUC-Cpo-022071	Cavia porcellus	98.59	0.00e+00	1807.00
IUUC-Csa-023882	Chlorocebus sabaeus	100.00	0.00e+00	1910.00
IUUC-Cin-025292	Ciona intestinalis	44.59	0.00e+00	748.00
IUUC-Csv-026109	Ciona savignyi	47.29	1.00e-148	520.00
IUUC-Cme-027338	Cyanidioschyzon merolae	56.36	4.00e-68	252.00
IUUC-Dno-029025	Dasypus novemcinctus	93.14	0.00e+00	1778.00
IUUC-Dor-030956	Dipodomys ordii	90.20	0.00e+00	1631.00
IUUC-Dse-031432	Dothistroma septosporum	40.43	3.00e-58	221.00
IUUC-Eca-034340	Equus caballus	99.47	0.00e+00	1846.00
IUUC-Eeu-034488	Erinaceus europaeus	89.24	0.00e+00	1268.00
IUUC-Fca-035552	Felis catus	95.92	0.00e+00	1857.00
IUUC-Fal-036618	Ficedula albicollis	95.07	0.00e+00	1718.00
IUUC-Gmo-038866	Gadus morhua	62.48	0.00e+00	776.00
IUUC-Gga-041146	Gallus gallus	93.90	0.00e+00	1761.00
IUUC-Gac-041679	Gasterosteus aculeatus	77.58	0.00e+00	1464.00
IUUC-Gma-043037	Glycine max	34.90	3.00e-138	486.00
IUUC-Ggo-045002	Gorilla gorilla	99.79	0.00e+00	1843.00
IUUC-Hsa-046052	Homo sapiens	99.90	0.00e+00	1908.00
IUUC-Hvu-047108	Hordeum vulgare	40.24	6.00e-123	434.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	95.93	0.00e+00	1859.00
IUUC-Lch-050107	Latimeria chalumnae	86.67	0.00e+00	1735.00
IUUC-Loc-052105	Lepisosteus oculatus	83.70	0.00e+00	1511.00
IUUC-Lma-052981	Leptosphaeria maculans	36.72	7.00e-66	247.00
IUUC-Laf-053645	Loxodonta africana	98.68	0.00e+00	1892.00
IUUC-Mcc-055586	Macaca mulatta	99.90	0.00e+00	1908.00
IUUC-Meu-056764	Macropus eugenii	90.15	0.00e+00	1003.00
IUUC-Mga-060162	Meleagris gallopavo	94.20	0.00e+00	1766.00
IUUC-Mmr-061105	Microcebus murinus	99.39	0.00e+00	1902.00
IUUC-Mdo-062107	Monodelphis domestica	97.25	0.00e+00	1845.00
IUUC-Mmu-063662	Mus musculus	97.76	0.00e+00	1878.00
IUUC-Mac-065239	Musa acuminata	33.23	9.00e-133	468.00
IUUC-Mpu-065868	Mustela putorius furo	97.00	0.00e+00	1887.00
IUUC-Mlu-068000	Myotis lucifugus	92.12	0.00e+00	1680.00
IUUC-Nle-069874	Nomascus leucogenys	99.89	0.00e+00	1882.00
IUUC-Opr-071212	Ochotona princeps	93.60	0.00e+00	1783.00
IUUC-Ont-071834	Oreochromis niloticus	79.58	0.00e+00	1458.00
IUUC-Ocu-074573	Oryctolagus cuniculus	99.49	0.00e+00	1906.00
IUUC-Oba-075427	Oryza barthii	34.63	8.00e-133	468.00
IUUC-Obr-076416	Oryza brachyantha	39.75	7.00e-119	421.00
IUUC-Ogu-078422	Oryza glumaepatula	34.63	7.00e-133	468.00
IUUC-Olo-080315	Oryza longistaminata	36.08	4.00e-145	508.00
IUUC-Ome-081271	Oryza meridionalis	35.92	5.00e-148	518.00
IUUC-Oni-082834	Oryza nivara	34.74	2.00e-133	469.00
IUUC-Opu-083691	Oryza punctata	34.95	4.00e-145	508.00
IUUC-Oru-084820	Oryza rufipogon	34.63	8.00e-133	468.00
IUUC-Osa-086139	Oryza sativa	36.00	2.00e-147	516.00
IUUC-Ola-086553	Oryzias latipes	59.50	0.00e+00	1104.00
IUUC-Oga-089022	Otolemur garnettii	95.41	0.00e+00	1853.00
IUUC-Oar-089767	Ovis aries	98.78	0.00e+00	1894.00
IUUC-Ptr-091319	Pan troglodytes	96.94	0.00e+00	1877.00
IUUC-Psi-093849	Pelodiscus sinensis	93.60	0.00e+00	1714.00
IUUC-Pma-094533	Petromyzon marinus	60.27	0.00e+00	1120.00
IUUC-Pno-094890	Phaeosphaeria nodorum	36.39	3.00e-59	224.00
IUUC-Pfo-097110	Poecilia formosa	78.28	0.00e+00	1454.00
IUUC-Pab-098664	Pongo abelii	100.00	0.00e+00	1910.00
IUUC-Pop-099801	Populus trichocarpa	36.99	5.00e-150	525.00
IUUC-Pca-100359	Procavia capensis	80.92	0.00e+00	1337.00
IUUC-Ppe-101587	Prunus persica	36.98	1.00e-148	520.00
IUUC-Pva-102394	Pteropus vampyrus	97.35	0.00e+00	1855.00
IUUC-Pgr-103546	Puccinia graminis	29.52	1.00e-67	252.00
IUUC-Pte-104102	Pyrenophora teres	35.50	7.00e-57	217.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	39.43	2.00e-56	215.00
IUUC-Rno-105383	Rattus norvegicus	95.21	0.00e+00	1853.00
IUUC-Sce-106170	Saccharomyces cerevisiae	36.97	2.00e-60	228.00
IUUC-Sha-107393	Sarcophilus harrisii	97.36	0.00e+00	1848.00
IUUC-Ssl-108461	Sclerotinia sclerotiorum	30.56	1.00e-13	71.60
IUUC-Smo-109356	Selaginella moellendorffii	46.85	1.00e-79	290.00
IUUC-Sit-109948	Setaria italica	36.37	3.00e-140	492.00
IUUC-Sly-111726	Solanum lycopersicum	39.74	1.00e-92	334.00
IUUC-Stu-112671	Solanum tuberosum	35.95	3.00e-145	509.00
IUUC-Sar-113498	Sorex araneus	98.37	0.00e+00	1885.00
IUUC-Sbi-114874	Sorghum bicolor	36.21	2.00e-142	499.00
IUUC-Sre-115130	Sporisorium reilianum	43.87	2.00e-77	285.00
IUUC-Ssc-115285	Sus scrofa	99.29	0.00e+00	1898.00
IUUC-Tgu-116529	Taeniopygia guttata	94.61	0.00e+00	1776.00
IUUC-Tru-118298	Takifugu rubripes	78.72	0.00e+00	1465.00
IUUC-Tsy-119117	Tarsius syrichta	89.79	0.00e+00	1157.00
IUUC-Tni-120093	Tetraodon nigroviridis	75.57	0.00e+00	1401.00
IUUC-Tae-125295	Triticum aestivum	35.65	1.00e-146	513.00
IUUC-Tur-126149	Triticum urartu	39.50	5.00e-106	379.00
IUUC-Tme-127062	Tuber melanosporum	31.40	2.00e-77	284.00
IUUC-Tbe-127672	Tupaia belangeri	91.30	0.00e+00	1252.00
IUUC-Ttr-128441	Tursiops truncatus	94.63	0.00e+00	1159.00
IUUC-Vpa-130469	Vicugna pacos	99.05	0.00e+00	1829.00
IUUC-Vvi-131010	Vitis vinifera	38.03	9.00e-150	524.00
IUUC-Xtr-132729	Xenopus tropicalis	84.13	0.00e+00	1624.00
IUUC-Xma-133550	Xiphophorus maculatus	78.38	0.00e+00	1452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence