iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011874

Ensembl Protein ID

ENSAMXP00000010344.1

UniProt Accession

W5KRY2; W5KRY2_ASTMX

Genbank Protein ID

ENSAMXP00000010344

Protein Name

Nitric oxide synthase-interacting protein

Genbank Nucleotide ID

APWO01092292

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000010075.1	ENSAMXT00000010344.1	ENSAMXP00000010344.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.10e-12	45.5	40	95

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl.......asggktcPvtrqpl 50
           + ++ +C +sl++ rdPvv+++G  y+r++I +++       a+++k   + +q l
   Q: 40   IKDFDCCCLSLQPCRDPVVTEDGFLYEREAILEYIlhqkldiAKKMKAYEKQKQAL 95
           567789*****************************443333333333555555555 PP

Organism

Astyanax mexicanus

Functional Description
(View)

Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity.

Protein Sequence
(Fasta)

MTRHGKNCTA GAVYTYHEKR KDTAASGYGT QSVRLGKDAI KDFDCCCLSL QPCRDPVVTE 60
DGFLYEREAI LEYILHQKLD IAKKMKAYEK QKQALKSEGQ LESCSEEREK VEKFKKREGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTTCAAGCC GGTGGGTCAC TTCCTATTCC GGCCAGCTTG GCTCAAGGTA AACAAACTGC 60
ACGGTTGATA TTTTATAAGT ACTTTATTTT TATACCTCTG ATGTAAAAAC AGTCTAAATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome

Interpro

IPR016818--Nitric_oxide_synth-interacting
IPR031790--Znf-NOSIP
IPR013083--Znf_RING/FYVE/PHD

Pfam

PF15906--zf-NOSIP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0050999--P:regulation of nitric-oxide synthase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000769	Aegilops tauschii	48.84	7.00e-16	78.60
IUUC-Aml-002069	Ailuropoda melanoleuca	62.74	9.00e-111	392.00
IUUC-Atr-002661	Amborella trichopoda	30.17	4.00e-24	105.00
IUUC-Aca-004630	Anolis carolinensis	65.26	7.00e-113	399.00
IUUC-Aly-006316	Arabidopsis lyrata	29.22	3.00e-26	112.00
IUUC-Ath-007000	Arabidopsis thaliana	28.57	2.00e-25	109.00
IUUC-Acl-008175	Aspergillus clavatus	30.00	8.00e-05	41.60
IUUC-Afl-008440	Aspergillus flavus	26.01	4.00e-09	55.80
IUUC-Afu-009012	Aspergillus fumigatus	26.45	2.00e-04	40.40
IUUC-Ang-009556	Aspergillus niger	33.75	1.00e-05	43.90
IUUC-Aor-009892	Aspergillus oryzae	29.66	2.00e-05	43.50
IUUC-Ate-010473	Aspergillus terreus	29.36	2.00e-04	41.20
IUUC-Bta-012956	Bos taurus	63.31	7.00e-114	403.00
IUUC-Bci-013897	Botrytis cinerea	38.75	1.00e-08	54.30
IUUC-Bdi-014968	Brachypodium distachyon	30.74	2.00e-29	122.00
IUUC-Bol-015578	Brassica oleracea	29.43	8.00e-30	124.00
IUUC-Bra-017234	Brassica rapa	29.43	8.00e-30	124.00
IUUC-Cel-018637	Caenorhabditis elegans	43.67	1.00e-54	206.00
IUUC-Cja-019632	Callithrix jacchus	65.26	5.00e-115	407.00
IUUC-Cfa-020192	Canis familiaris	63.14	1.00e-112	399.00
IUUC-Cpo-021939	Cavia porcellus	64.94	3.00e-116	410.00
IUUC-Cre-023005	Chlamydomonas reinhardtii	32.31	4.00e-34	138.00
IUUC-Csa-023802	Chlorocebus sabaeus	63.46	3.00e-113	401.00
IUUC-Cho-024637	Choloepus hoffmanni	48.52	2.00e-36	145.00
IUUC-Cin-025180	Ciona intestinalis	51.94	4.00e-83	301.00
IUUC-Csv-026206	Ciona savignyi	56.74	6.00e-43	166.00
IUUC-Cgl-026696	Colletotrichum gloeosporioides	34.78	9.00e-10	57.80
IUUC-Cne-026827	Cryptococcus neoformans	38.82	1.00e-07	50.80
IUUC-Dre-028092	Danio rerio	82.79	8.00e-135	473.00
IUUC-Dno-029501	Dasypus novemcinctus	59.37	7.00e-99	353.00
IUUC-Dor-030542	Dipodomys ordii	65.26	2.00e-114	404.00
IUUC-Dme-031734	Drosophila melanogaster	47.73	5.00e-77	280.00
IUUC-Eca-033577	Equus caballus	63.69	1.00e-114	405.00
IUUC-Fca-035761	Felis catus	64.61	2.00e-114	404.00
IUUC-Fso-038208	Fusarium solani	27.45	4.00e-05	42.40
IUUC-Gmo-038523	Gadus morhua	70.83	2.00e-68	251.00
IUUC-Ggr-040087	Gaeumannomyces graminis	35.90	2.00e-07	50.10
IUUC-Gac-042621	Gasterosteus aculeatus	76.10	7.00e-123	433.00
IUUC-Gma-042698	Glycine max	30.36	2.00e-27	115.00
IUUC-Ggo-045357	Gorilla gorilla	63.78	2.00e-113	402.00
IUUC-Hsa-046195	Homo sapiens	63.78	2.00e-113	402.00
IUUC-Hvu-047174	Hordeum vulgare	30.42	1.00e-29	123.00
IUUC-Itr-048487	Ictidomys tridecemlineatus	64.94	5.00e-114	403.00
IUUC-Lch-050569	Latimeria chalumnae	64.13	4.00e-102	363.00
IUUC-Lpe-050992	Leersia perrieri	33.33	7.00e-18	85.10
IUUC-Loc-052522	Lepisosteus oculatus	76.55	2.00e-119	422.00
IUUC-Lma-053254	Leptosphaeria maculans	34.48	6.00e-07	48.50
IUUC-Laf-053397	Loxodonta africana	63.06	1.00e-112	399.00
IUUC-Mcc-054681	Macaca mulatta	63.78	5.00e-114	404.00
IUUC-Meu-056723	Macropus eugenii	64.94	7.00e-114	403.00
IUUC-Mor-056961	Magnaporthe oryzae	33.98	1.00e-08	54.30
IUUC-Mtr-058063	Medicago truncatula	29.90	2.00e-29	122.00
IUUC-Mla-059004	Melampsora laricipopulina	28.39	3.00e-18	85.50
IUUC-Mvi-060460	Microbotryum violaceum	26.91	1.00e-18	87.00
IUUC-Mmr-060847	Microcebus murinus	63.69	2.00e-114	404.00
IUUC-Mdo-062480	Monodelphis domestica	63.23	3.00e-112	397.00
IUUC-Mmu-063809	Mus musculus	63.96	3.00e-113	400.00
IUUC-Mac-064870	Musa acuminata	31.02	4.00e-31	128.00
IUUC-Mpu-066322	Mustela putorius furo	63.78	5.00e-114	404.00
IUUC-Mlu-067556	Myotis lucifugus	65.58	1.00e-114	405.00
IUUC-Nfi-068440	Neosartorya fischeri	26.45	2.00e-04	40.40
IUUC-Ncr-068898	Neurospora crassa	34.62	3.00e-06	46.20
IUUC-Nle-070049	Nomascus leucogenys	63.78	1.00e-113	402.00
IUUC-Opr-070972	Ochotona princeps	65.58	7.00e-115	406.00
IUUC-Ont-071682	Oreochromis niloticus	79.41	8.00e-130	456.00
IUUC-Oan-073296	Ornithorhynchus anatinus	89.83	1.00e-29	121.00
IUUC-Ocu-074218	Oryctolagus cuniculus	60.26	5.00e-100	357.00
IUUC-Oba-075284	Oryza barthii	30.13	3.00e-28	118.00
IUUC-Obr-076651	Oryza brachyantha	30.74	7.00e-31	127.00
IUUC-Ogl-077899	Oryza glaberrima	30.13	3.00e-28	118.00
IUUC-Ogu-078477	Oryza glumaepatula	30.45	2.00e-28	119.00
IUUC-Oin-080011	Oryza indica	30.13	3.00e-28	118.00
IUUC-Olo-080545	Oryza longistaminata	29.71	4.00e-22	99.00
IUUC-Ome-081543	Oryza meridionalis	30.13	3.00e-28	118.00
IUUC-Oni-082955	Oryza nivara	30.13	3.00e-28	118.00
IUUC-Opu-083565	Oryza punctata	30.74	2.00e-28	119.00
IUUC-Oru-084474	Oryza rufipogon	30.13	3.00e-28	118.00
IUUC-Osa-085913	Oryza sativa	30.13	3.00e-28	118.00
IUUC-Ola-086851	Oryzias latipes	76.28	1.00e-131	462.00
IUUC-Olu-087724	Ostreococcus lucimarinus	30.10	3.00e-10	59.30
IUUC-Oga-087970	Otolemur garnettii	65.05	1.00e-112	399.00
IUUC-Oar-089756	Ovis aries	62.01	8.00e-107	379.00
IUUC-Ptr-091485	Pan troglodytes	62.82	4.00e-110	390.00
IUUC-Pan-091832	Papio anubis	63.78	9.00e-114	402.00
IUUC-Pma-094551	Petromyzon marinus	61.69	3.00e-98	351.00
IUUC-Ppa-095255	Physcomitrella patens	29.70	2.00e-27	115.00
IUUC-Pfo-096373	Poecilia formosa	78.57	1.00e-132	465.00
IUUC-Pab-098247	Pongo abelii	63.78	2.00e-113	402.00
IUUC-Pop-099186	Populus trichocarpa	30.74	3.00e-30	125.00
IUUC-Pca-100677	Procavia capensis	57.99	2.00e-87	315.00
IUUC-Ppe-101403	Prunus persica	45.35	6.00e-15	74.70
IUUC-Pva-103000	Pteropus vampyrus	63.69	6.00e-115	406.00
IUUC-Pgr-103663	Puccinia graminis	28.17	3.00e-24	105.00
IUUC-Ptt-103712	Puccinia triticina	38.46	3.00e-08	52.00
IUUC-Pte-104287	Pyrenophora teres	31.25	3.00e-06	45.80
IUUC-Pyt-104579	Pyrenophora triticirepentis	31.25	3.00e-06	46.20
IUUC-Rno-106069	Rattus norvegicus	64.29	1.00e-113	402.00
IUUC-Sha-106553	Sarcophilus harrisii	62.99	6.00e-113	400.00
IUUC-Smo-108874	Selaginella moellendorffii	32.89	1.00e-34	140.00
IUUC-Sit-110307	Setaria italica	31.07	1.00e-27	116.00
IUUC-Sly-111094	Solanum lycopersicum	30.87	4.00e-31	128.00
IUUC-Stu-112363	Solanum tuberosum	30.87	3.00e-31	128.00
IUUC-Sar-113480	Sorex araneus	63.96	5.00e-111	394.00
IUUC-Sbi-113939	Sorghum bicolor	31.39	6.00e-29	121.00
IUUC-Ssc-115644	Sus scrofa	63.78	6.00e-114	403.00
IUUC-Tru-118781	Takifugu rubripes	75.90	6.00e-129	453.00
IUUC-Tni-119672	Tetraodon nigroviridis	74.71	3.00e-35	139.00
IUUC-Tca-121795	Theobroma cacao	30.54	9.00e-31	127.00
IUUC-Tre-122037	Trichoderma reesei	32.47	2.00e-06	46.60
IUUC-Tvi-122524	Trichoderma virens	25.35	1.00e-10	60.50
IUUC-Tae-125162	Triticum aestivum	29.89	2.00e-23	102.00
IUUC-Tur-126387	Triticum urartu	30.26	4.00e-23	102.00
IUUC-Tme-127111	Tuber melanosporum	36.90	2.00e-07	50.10
IUUC-Ttr-128227	Tursiops truncatus	63.96	7.00e-113	400.00
IUUC-Vda-129924	Verticillium dahliae	23.94	1.00e-11	64.30
IUUC-Vpa-130802	Vicugna pacos	71.91	4.00e-34	138.00
IUUC-Vvi-131105	Vitis vinifera	30.03	2.00e-28	119.00
IUUC-Xtr-132830	Xenopus tropicalis	62.38	5.00e-110	390.00
IUUC-Xma-133618	Xiphophorus maculatus	77.60	1.00e-126	445.00
IUUC-Zma-135389	Zea mays	30.74	1.00e-27	116.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence