iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068554

Ensembl Protein ID

CADNFIAP00007597

UniProt Accession

A1DFM0; A1DFM0_NEOFI

Genbank Protein ID

EAW18177.1

Protein Name

HECT domain protein

Genbank Nucleotide ID

DS027696

Gene Name

NFIA_081210

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00007764	CADNFIAT00007764	CADNFIAP00007597

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.20e-70	234.9	951	1336

Active Site

Position(s)	Description	Evidence
1305	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 14   vgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllgkk 104
           +gEegld+gGv++ef+  l+++  +p++g+f+++++ + +++ +p s     e l  Fe+lG l+ +a+++g  l+++++ +fy++llg k
   Q: 951  EGEEGLDHGGVQQEFFRVLMAQALDPSYGMFTMDARTRISWF-QPCSL----EPLYKFELLGLLMSLAIYNGLTLPVNFPVAFYRKLLGLK 1036
           47*****************************99999888877.66665....679***********************************9 PP
   S: 105  lsl.edleevdpelykslkeikenaes................................................................ 130
           ++  e++ +  pel+k l+ +++ ++                                                                 
   Q: 1037 VKHlEHIRDGWPELAKGLELLLSWQDGdvgdvfmrtyeftfeafgavetvdmekvdrdavwplrardrgksselatnwselsqhadpadls 1127
           9877******************99844566666667777777788888888888999999999999999999999**************** PP
   S: 131  ...dieelgldltfsvseei...lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeele 215
              ++ + ++d+  + s++        +++   p  e   VtneN+ ++vk+++ +   ++i+ q+eaf +Gf++ ++   ls+Ft+e ++
   Q: 1128 ppcSMAADHADFLECGSSHRstsERLDHCVPTPPVEEASLVTNENRAQFVKDYIFWLTDKSIRPQFEAFARGFYTCLDRAALSIFTPEAFK 1218
           ***66666777766633332222333334445888999***************************************************** PP
   S: 216  llicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCf 305
           +++ G +eid+e+l+++++y+gg+ + +++i+ Fw+++++fs+e+++++L+FvT s+r+P++G+a+++   fvi++    d+rlP+s TCf
   Q: 1219 TVVEGIQEIDLEELERHARYEGGFGPHHRVIRDFWSIVKGFSEEKKAQLLEFVTASDRVPVNGIASIM---FVIQRnGVGDARLPTSLTCF 1306
           ********************************************************************...9998857788********** PP
   S: 306  nyLkLPeYsskeilkekLlyAieetkgFel 335
            +L LPeYssk++l+ekL  A e+++gF++
   Q: 1307 GRLLLPEYSSKSVLEEKLNKALENARGFGV 1336
           ****************************86 PP

Organism

Neosartorya fischeri

Protein Sequence
(Fasta)

MTRLRGASVS SYDAGVDRSQ FHRSKLPSNA PDIIVQNTVD VSDPAQVLLW YREERRRQFN 60
LLVRKYKNQL LHGCQDPACR TPTCASYRRR VSEGPYRRYT ELSARTLACY LASLDNPESG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTAGGC TCCGCGGAGC TTCAGTGAGC TCGTACGATG CTGGTGTCGA CCGGTCTCAG 60
TTCCATCGGT CAAAGCTTCC TTCAAACGCG CCAGATATCA TCGTTCAGAA CACCGTCGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR032353--AZUL
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF16558--AZUL
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

nfi:NFIA_081210

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008265	Aspergillus clavatus	72.74	0.00e+00	1774.00
IUUC-Afl-008437	Aspergillus flavus	64.91	0.00e+00	1429.00
IUUC-Afu-008852	Aspergillus fumigatus	95.06	0.00e+00	2487.00
IUUC-Ani-009330	Aspergillus nidulans	64.54	0.00e+00	1318.00
IUUC-Ang-009616	Aspergillus niger	65.39	0.00e+00	1680.00
IUUC-Aor-010162	Aspergillus oryzae	64.99	0.00e+00	1646.00
IUUC-Ate-010475	Aspergillus terreus	63.68	0.00e+00	1563.00
IUUC-Bgr-012015	Blumeria graminis	32.32	5.00e-169	587.00
IUUC-Bci-013608	Botrytis cinerea	37.89	2.00e-150	525.00
IUUC-Cgl-026488	Colletotrichum gloeosporioides	32.50	3.00e-154	538.00
IUUC-Dse-031435	Dothistroma septosporum	29.58	1.00e-77	283.00
IUUC-Fox-037915	Fusarium oxysporum	38.67	2.00e-134	471.00
IUUC-Fso-038357	Fusarium solani	40.38	2.00e-128	451.00
IUUC-Ggr-039765	Gaeumannomyces graminis	34.68	4.00e-156	544.00
IUUC-Lma-053245	Leptosphaeria maculans	32.56	2.00e-110	392.00
IUUC-Mor-057108	Magnaporthe oryzae	45.07	6.00e-133	467.00
IUUC-Ncr-068759	Neurospora crassa	32.13	2.00e-143	502.00
IUUC-Pno-094886	Phaeosphaeria nodorum	37.06	1.00e-141	496.00
IUUC-Pte-104055	Pyrenophora teres	33.33	3.00e-79	288.00
IUUC-Pyt-104647	Pyrenophora triticirepentis	33.49	1.00e-87	316.00
IUUC-Ssl-108420	Sclerotinia sclerotiorum	38.54	1.00e-152	532.00
IUUC-Tre-121985	Trichoderma reesei	39.43	2.00e-139	488.00
IUUC-Tvi-122335	Trichoderma virens	36.29	2.00e-135	475.00
IUUC-Tme-127119	Tuber melanosporum	34.45	1.00e-98	353.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence