iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000007700.5	ENSGALT00000012477.5	ENSGALP00000012463.4
ENSGALG00000007700.5	ENSGALT00000051098.1	ENSGALP00000057528.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.50e-13	48.4	511	560

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 511  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 560
           79***********************..9*********..7************97 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MTVLLLVVLQ MWKATAGHSI AVSQDDGADD WETDPDFVND VSEKEQRWGA KTVKGSGHQE 60
HINIHQLREN VFQEHQTIKE KELETGPKAS HGYGGKFGVE QDRMDKSAVG HEYQSKLSKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTGCAAAAC AGCTATTGCT ATGTCCTAAG TTTGTGCACA GGGTGTGGAA TTAGCAGCAG 60
TCCTCAGGAA GGGACGTGGA GTGGGATTGC TGCCTGAACA GAAGTCCTCA GTGCAGAGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	83.12	0.00e+00	876.00
IUUC-Apl-003745	Anas platyrhynchos	96.23	0.00e+00	907.00
IUUC-Aca-004438	Anolis carolinensis	85.11	0.00e+00	940.00
IUUC-Bgr-012041	Blumeria graminis	57.89	6.00e-16	79.30
IUUC-Bta-013563	Bos taurus	82.67	0.00e+00	831.00
IUUC-Bci-013690	Botrytis cinerea	58.82	5.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	80.72	0.00e+00	863.00
IUUC-Cpo-022303	Cavia porcellus	83.21	0.00e+00	927.00
IUUC-Csa-023431	Chlorocebus sabaeus	84.66	0.00e+00	860.00
IUUC-Cin-025677	Ciona intestinalis	61.33	3.00e-120	425.00
IUUC-Csv-026140	Ciona savignyi	66.00	1.00e-110	392.00
IUUC-Dre-028012	Danio rerio	73.46	2.00e-151	528.00
IUUC-Dno-029332	Dasypus novemcinctus	77.08	0.00e+00	724.00
IUUC-Dse-031182	Dothistroma septosporum	37.38	1.00e-11	65.50
IUUC-Eca-033801	Equus caballus	83.87	0.00e+00	865.00
IUUC-Fca-035633	Felis catus	82.44	0.00e+00	713.00
IUUC-Fal-036775	Ficedula albicollis	92.78	0.00e+00	881.00
IUUC-Fox-037778	Fusarium oxysporum	59.65	1.00e-14	75.10
IUUC-Gmo-038507	Gadus morhua	56.96	2.00e-20	93.60
IUUC-Gac-042253	Gasterosteus aculeatus	56.40	7.00e-118	417.00
IUUC-Hsa-046818	Homo sapiens	85.02	0.00e+00	863.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	81.56	0.00e+00	806.00
IUUC-Lch-050199	Latimeria chalumnae	73.83	2.00e-153	535.00
IUUC-Loc-052855	Lepisosteus oculatus	76.40	3.00e-156	544.00
IUUC-Laf-053866	Loxodonta africana	84.68	0.00e+00	917.00
IUUC-Mcc-055515	Macaca mulatta	84.48	0.00e+00	858.00
IUUC-Mpo-057325	Magnaporthe poae	50.98	2.00e-10	58.20
IUUC-Mga-059791	Meleagris gallopavo	96.09	0.00e+00	954.00
IUUC-Mmr-061147	Microcebus murinus	85.20	0.00e+00	817.00
IUUC-Mdo-062660	Monodelphis domestica	61.39	5.00e-176	611.00
IUUC-Mmu-064023	Mus musculus	83.75	0.00e+00	846.00
IUUC-Mpu-065867	Mustela putorius furo	72.88	0.00e+00	740.00
IUUC-Mlu-067704	Myotis lucifugus	77.30	0.00e+00	733.00
IUUC-Ont-071873	Oreochromis niloticus	80.60	5.00e-173	600.00
IUUC-Oan-073528	Ornithorhynchus anatinus	86.03	3.00e-170	590.00
IUUC-Oga-088028	Otolemur garnettii	84.12	0.00e+00	851.00
IUUC-Oar-090203	Ovis aries	82.73	0.00e+00	767.00
IUUC-Pan-092594	Papio anubis	80.14	0.00e+00	805.00
IUUC-Psi-093389	Pelodiscus sinensis	89.81	0.00e+00	901.00
IUUC-Pma-094161	Petromyzon marinus	47.67	4.00e-88	318.00
IUUC-Pfo-096269	Poecilia formosa	61.81	1.00e-112	399.00
IUUC-Pab-097913	Pongo abelii	77.98	0.00e+00	758.00
IUUC-Rno-105489	Rattus norvegicus	83.21	0.00e+00	827.00
IUUC-Sha-107308	Sarcophilus harrisii	71.81	0.00e+00	684.00
IUUC-Tgu-117049	Taeniopygia guttata	84.63	0.00e+00	786.00
IUUC-Tru-118718	Takifugu rubripes	77.03	1.00e-161	562.00
IUUC-Tni-120535	Tetraodon nigroviridis	70.24	7.00e-150	523.00
IUUC-Tre-122167	Trichoderma reesei	59.18	1.00e-11	65.10
IUUC-Tvi-122614	Trichoderma virens	59.18	9.00e-12	65.50
IUUC-Tme-127196	Tuber melanosporum	59.65	6.00e-15	76.30
IUUC-Xtr-131797	Xenopus tropicalis	67.31	0.00e+00	662.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence