iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066418

Ensembl Protein ID

ENSMPUP00000015850.1

UniProt Accession

M3YWZ0; M3YWZ0_MUSPF

Genbank Protein ID

ENSMPUP00000015850

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01027891

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000015955.1	ENSMPUT00000016091.1	ENSMPUP00000015850.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.70e-27	93.0	226	299

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 226  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 299
           69********************************************************************9986 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MKGKEEKEGG ARLGAGGGSP EKSPSAQELK EQGNRLFVGR KYPEAAACYG RAITRNPLVA 60
VYYTNRALCY LKMQQHEQAL ADCRRALELD GQSVKAHFFL GQCQLEMESY DEAIANLQRA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGGGCA AGGAGGAGAA GGAGGGTGGC GCGCGGTTGG GCGCCGGCGG CGGAAGCCCC 60
GAAAAGAGCC CGAGCGCGCA GGAGCTCAAG GAGCAGGGCA ACCGGCTCTT CGTGGGTCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	36.51	8.00e-39	153.00
IUUC-Aml-001350	Ailuropoda melanoleuca	100.00	1.00e-149	521.00
IUUC-Atr-003168	Amborella trichopoda	35.85	3.00e-31	128.00
IUUC-Apl-003736	Anas platyrhynchos	88.84	3.00e-133	467.00
IUUC-Aca-004751	Anolis carolinensis	86.62	5.00e-144	503.00
IUUC-Aly-006292	Arabidopsis lyrata	34.77	1.00e-44	172.00
IUUC-Ath-007012	Arabidopsis thaliana	34.41	6.00e-43	167.00
IUUC-Acl-008025	Aspergillus clavatus	31.91	1.00e-36	146.00
IUUC-Afl-008721	Aspergillus flavus	31.82	7.00e-34	137.00
IUUC-Afu-008853	Aspergillus fumigatus	33.45	3.00e-36	145.00
IUUC-Ani-009349	Aspergillus nidulans	32.19	5.00e-35	141.00
IUUC-Ang-009674	Aspergillus niger	33.33	7.00e-33	134.00
IUUC-Aor-010014	Aspergillus oryzae	30.27	2.00e-28	119.00
IUUC-Ate-010467	Aspergillus terreus	28.28	3.00e-27	115.00
IUUC-Ame-011215	Astyanax mexicanus	61.51	1.00e-94	339.00
IUUC-Bgr-011971	Blumeria graminis	30.50	3.00e-25	108.00
IUUC-Bta-013025	Bos taurus	99.00	2.00e-178	617.00
IUUC-Bci-013945	Botrytis cinerea	39.51	7.00e-15	74.30
IUUC-Bdi-014483	Brachypodium distachyon	38.77	3.00e-45	175.00
IUUC-Bol-015676	Brassica oleracea	35.34	2.00e-46	179.00
IUUC-Bra-017897	Brassica rapa	32.06	1.00e-29	123.00
IUUC-Cel-018323	Caenorhabditis elegans	40.79	6.00e-55	207.00
IUUC-Cja-019657	Callithrix jacchus	96.49	5.00e-167	579.00
IUUC-Cfa-020470	Canis familiaris	99.57	4.00e-137	479.00
IUUC-Cpo-022033	Cavia porcellus	97.36	1.00e-171	594.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	28.28	6.00e-29	120.00
IUUC-Csa-023038	Chlorocebus sabaeus	97.54	2.00e-160	557.00
IUUC-Cin-025381	Ciona intestinalis	53.02	9.00e-88	316.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	32.62	1.00e-39	156.00
IUUC-Dre-027610	Danio rerio	80.35	2.00e-138	484.00
IUUC-Dno-030087	Dasypus novemcinctus	96.70	2.00e-170	591.00
IUUC-Dor-031029	Dipodomys ordii	91.23	2.00e-150	524.00
IUUC-Dse-031275	Dothistroma septosporum	32.31	3.00e-28	118.00
IUUC-Dme-031856	Drosophila melanogaster	57.71	2.00e-94	338.00
IUUC-Ete-033087	Echinops telfairi	94.85	2.00e-141	494.00
IUUC-Eca-033512	Equus caballus	98.80	2.00e-148	517.00
IUUC-Eeu-034763	Erinaceus europaeus	94.02	4.00e-100	356.00
IUUC-Fca-036460	Felis catus	99.63	8.00e-163	565.00
IUUC-Fal-037441	Ficedula albicollis	89.16	2.00e-151	528.00
IUUC-Fox-038028	Fusarium oxysporum	31.06	5.00e-39	154.00
IUUC-Fso-038323	Fusarium solani	32.62	2.00e-29	122.00
IUUC-Gmo-038511	Gadus morhua	78.60	5.00e-133	466.00
IUUC-Ggr-039964	Gaeumannomyces graminis	33.68	3.00e-28	118.00
IUUC-Gga-040854	Gallus gallus	89.16	9.00e-151	525.00
IUUC-Gac-042175	Gasterosteus aculeatus	77.89	1.00e-129	455.00
IUUC-Gma-044046	Glycine max	36.23	4.00e-43	167.00
IUUC-Ggo-044512	Gorilla gorilla	97.54	2.00e-160	557.00
IUUC-Hsa-046872	Homo sapiens	97.54	2.00e-160	557.00
IUUC-Hvu-047661	Hordeum vulgare	35.29	4.00e-39	154.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	97.19	2.00e-167	581.00
IUUC-Lch-049988	Latimeria chalumnae	80.07	7.00e-134	469.00
IUUC-Lpe-050693	Leersia perrieri	35.14	3.00e-43	168.00
IUUC-Loc-052195	Lepisosteus oculatus	79.61	1.00e-117	415.00
IUUC-Lma-053207	Leptosphaeria maculans	30.29	7.00e-29	122.00
IUUC-Laf-054584	Loxodonta africana	96.70	1.00e-170	592.00
IUUC-Mcc-054689	Macaca mulatta	97.54	2.00e-160	557.00
IUUC-Meu-055998	Macropus eugenii	90.40	2.00e-85	308.00
IUUC-Mor-057116	Magnaporthe oryzae	33.68	3.00e-40	158.00
IUUC-Mtr-057684	Medicago truncatula	33.58	1.00e-38	152.00
IUUC-Mga-059332	Meleagris gallopavo	89.24	6.00e-133	466.00
IUUC-Mmr-061377	Microcebus murinus	97.54	4.00e-160	556.00
IUUC-Mdo-061963	Monodelphis domestica	92.31	5.00e-149	519.00
IUUC-Mmu-063146	Mus musculus	97.04	4.00e-161	560.00
IUUC-Mac-064932	Musa acuminata	33.98	6.00e-28	116.00
IUUC-Mlu-067066	Myotis lucifugus	99.01	0.00e+00	625.00
IUUC-Nfi-068601	Neosartorya fischeri	33.45	4.00e-36	144.00
IUUC-Ncr-068761	Neurospora crassa	41.67	4.00e-17	82.00
IUUC-Nle-069374	Nomascus leucogenys	97.54	2.00e-160	557.00
IUUC-Opr-070765	Ochotona princeps	91.26	1.00e-101	361.00
IUUC-Ont-071996	Oreochromis niloticus	81.75	3.00e-132	464.00
IUUC-Oba-075967	Oryza barthii	36.10	2.00e-44	172.00
IUUC-Obr-076440	Oryza brachyantha	34.98	1.00e-31	132.00
IUUC-Ogl-077495	Oryza glaberrima	36.10	2.00e-44	172.00
IUUC-Ogu-078247	Oryza glumaepatula	36.76	1.00e-40	159.00
IUUC-Oin-079376	Oryza indica	36.10	2.00e-44	172.00
IUUC-Olo-081083	Oryza longistaminata	31.52	2.00e-31	129.00
IUUC-Ome-081935	Oryza meridionalis	29.17	4.00e-21	97.40
IUUC-Oni-082535	Oryza nivara	36.76	1.00e-40	159.00
IUUC-Opu-083794	Oryza punctata	35.15	7.00e-44	171.00
IUUC-Oru-085153	Oryza rufipogon	36.10	4.00e-44	171.00
IUUC-Osa-085936	Oryza sativa	35.51	1.00e-16	79.70
IUUC-Ola-087081	Oryzias latipes	79.30	1.00e-135	475.00
IUUC-Olu-087790	Ostreococcus lucimarinus	31.54	1.00e-31	129.00
IUUC-Oga-088331	Otolemur garnettii	97.36	1.00e-164	571.00
IUUC-Oar-089987	Ovis aries	96.09	5.00e-144	503.00
IUUC-Ptr-090855	Pan troglodytes	97.54	2.00e-160	557.00
IUUC-Pan-092801	Papio anubis	91.93	2.00e-158	551.00
IUUC-Psi-093393	Pelodiscus sinensis	88.05	2.00e-132	464.00
IUUC-Pma-094680	Petromyzon marinus	68.57	2.00e-112	398.00
IUUC-Pno-094913	Phaeosphaeria nodorum	33.79	2.00e-35	142.00
IUUC-Ppa-095976	Physcomitrella patens	33.86	1.00e-43	169.00
IUUC-Pfo-096850	Poecilia formosa	79.65	9.00e-129	452.00
IUUC-Pab-097963	Pongo abelii	97.54	2.00e-160	557.00
IUUC-Pop-098805	Populus trichocarpa	43.88	5.00e-25	107.00
IUUC-Pca-100788	Procavia capensis	97.69	5.00e-173	599.00
IUUC-Ppe-101221	Prunus persica	35.25	2.00e-44	172.00
IUUC-Pva-103076	Pteropus vampyrus	98.35	7.00e-179	619.00
IUUC-Pte-104237	Pyrenophora teres	31.47	2.00e-33	135.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	31.47	1.00e-33	136.00
IUUC-Rno-105204	Rattus norvegicus	97.04	2.00e-161	561.00
IUUC-Sha-106579	Sarcophilus harrisii	86.72	2.00e-128	451.00
IUUC-Smo-109525	Selaginella moellendorffii	36.13	3.00e-42	164.00
IUUC-Sit-110072	Setaria italica	36.10	3.00e-41	162.00
IUUC-Sly-111473	Solanum lycopersicum	37.37	2.00e-45	175.00
IUUC-Stu-112353	Solanum tuberosum	36.43	2.00e-43	168.00
IUUC-Sbi-114250	Sorghum bicolor	37.32	5.00e-45	174.00
IUUC-Ssc-115416	Sus scrofa	99.01	2.00e-180	624.00
IUUC-Tgu-117272	Taeniopygia guttata	94.44	3.00e-57	212.00
IUUC-Tru-117777	Takifugu rubripes	80.35	1.00e-130	459.00
IUUC-Tni-120572	Tetraodon nigroviridis	81.40	1.00e-131	462.00
IUUC-Tca-121149	Theobroma cacao	38.63	8.00e-50	190.00
IUUC-Tre-122230	Trichoderma reesei	31.88	3.00e-31	128.00
IUUC-Tvi-122678	Trichoderma virens	35.25	4.00e-42	164.00
IUUC-Tae-122986	Triticum aestivum	35.16	3.00e-42	165.00
IUUC-Tur-126009	Triticum urartu	35.20	5.00e-38	150.00
IUUC-Tme-126948	Tuber melanosporum	35.94	2.00e-41	162.00
IUUC-Ttr-129031	Tursiops truncatus	96.37	2.00e-171	594.00
IUUC-Vda-130023	Verticillium dahliae	32.97	5.00e-40	157.00
IUUC-Vvi-131091	Vitis vinifera	40.80	5.00e-25	106.00
IUUC-Xtr-132871	Xenopus tropicalis	83.93	7.00e-131	459.00
IUUC-Xma-134220	Xiphophorus maculatus	80.00	3.00e-129	454.00
IUUC-Yli-134462	Yarrowia lipolytica	28.98	9.00e-29	120.00
IUUC-Zma-135007	Zea mays	37.32	4.00e-44	171.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence