iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003411

Ensembl Protein ID

ENSAPLP00000004922.1

UniProt Accession

U3ICF0; U3ICF0_ANAPL

Genbank Protein ID

ENSAPLP00000004922

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01114892

Gene Name

USP12

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000005359.1	ENSAPLT00000005546.1	ENSAPLP00000004922.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.40e-98	329.1	39	367

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +Gl N+gNtCY+NSvLQ+L++++++r+ +l  +k++      + +k++ll++l++lf+++   k+k +++ p+++++ l+ke+e f++y
   Q: 39   FGLVNFGNTCYCNSVLQALYFCRPFRDKVLA-YKSQ------PRKKENLLTCLADLFHSIAtqKKKVGVIPPKKFITRLRKENELFDNY 120
           6******************************.4444......456789************976777779******************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpv 176
           +qqDa+Efl++ll+++ + l    ++++++e+++ +    ++ +e++    +++++++Fqg+l+++++cl+c+++ss++e+fldls++v
   Q: 121  MQQDAHEFLNYLLNTIADIL----QEERKQEKQNGRLPNGNIDNENNSPPDPTWVHEIFQGTLTNETRCLTCETISSKDEDFLDLSVDV 205
           ********************....4466666666666777777888888899************************************* PP
   S: 177  pgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfc 265
           ++++     s+++cL+ f+++e+l++e kyyce+c++kqea k++k+kklP +L lhLkRf++  + ++ +k++ +v fpleL l  f+
   Q: 206  EQNT-----SITHCLRGFSNTETLCSEYKYYCEECRSKQEAHKRMKVKKLPMILALHLKRFKYMDQLHRYTKLSYRVVFPLELRL--FN 287
           ****.....9**********************************************************************66665..77 PP
   S: 266  tspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetg.........staYvlfYkr 337
           ts +   + ++ Y+L+avvvH G +++ GHY+a+vk+ ++ WllfdD+ V++++ + ++e+ g         +++Y+lfY++
   Q: 288  TSGDA-TNPDRMYDLVAVVVHCGsGPNRGHYIAIVKS-HDFWLLFDDDIVEKIDAQAIEEFYGltsdisknsESGYILFYQS 367
           77444.4469***************************.555*******************999*****************97 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

LSSSLLIRGT ASMCAVGANA SALEKEIGPE QFPVNEHYFG LVNFGNTCYC NSVLQALYFC 60
RPFRDKVLAY KSQPRKKENL LTCLADLFHS IATQKKKVGV IPPKKFITRL RKENELFDNY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTCTTCCT CTCTCCTGAT TAGAGGAACT GCTTCAGTAT ATGTAAATTC AGTAAAATCT 60
GAGCCTTACA ATCTGAGATC TGAAGATGCA GGTTTGATAT AGAAAGGTCT ACAGCTGCGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001964	Ailuropoda melanoleuca	95.68	0.00e+00	737.00
IUUC-Aca-005212	Anolis carolinensis	95.36	0.00e+00	732.00
IUUC-Ago-007871	Ashbya gossypii	38.70	2.00e-49	189.00
IUUC-Acl-008239	Aspergillus clavatus	48.67	3.00e-77	282.00
IUUC-Afu-008816	Aspergillus fumigatus	49.16	3.00e-77	283.00
IUUC-Ani-009137	Aspergillus nidulans	48.48	3.00e-76	279.00
IUUC-Ang-009703	Aspergillus niger	48.82	1.00e-79	290.00
IUUC-Aor-009901	Aspergillus oryzae	49.16	3.00e-79	289.00
IUUC-Ate-010431	Aspergillus terreus	49.50	5.00e-78	285.00
IUUC-Ame-011015	Astyanax mexicanus	91.97	0.00e+00	706.00
IUUC-Bgr-012071	Blumeria graminis	44.74	6.00e-75	275.00
IUUC-Bta-012981	Bos taurus	96.44	0.00e+00	744.00
IUUC-Bci-013837	Botrytis cinerea	41.56	6.00e-73	268.00
IUUC-Bol-015138	Brassica oleracea	59.51	4.00e-123	434.00
IUUC-Cja-018831	Callithrix jacchus	96.45	0.00e+00	740.00
IUUC-Cfa-020534	Canis familiaris	96.17	0.00e+00	739.00
IUUC-Cpo-021703	Cavia porcellus	98.87	0.00e+00	731.00
IUUC-Cho-024902	Choloepus hoffmanni	82.20	2.00e-169	587.00
IUUC-Cgl-026611	Colletotrichum gloeosporioides	43.37	1.00e-74	273.00
IUUC-Dre-027845	Danio rerio	91.97	0.00e+00	708.00
IUUC-Dno-029460	Dasypus novemcinctus	98.87	0.00e+00	732.00
IUUC-Dor-030972	Dipodomys ordii	98.82	5.00e-151	526.00
IUUC-Dse-031470	Dothistroma septosporum	48.54	3.00e-77	282.00
IUUC-Ete-033125	Echinops telfairi	78.23	3.00e-131	460.00
IUUC-Eca-033439	Equus caballus	98.87	0.00e+00	731.00
IUUC-Fca-035524	Felis catus	98.87	0.00e+00	734.00
IUUC-Fal-036833	Ficedula albicollis	98.31	0.00e+00	739.00
IUUC-Gmo-038763	Gadus morhua	91.16	0.00e+00	702.00
IUUC-Gga-041151	Gallus gallus	97.53	0.00e+00	752.00
IUUC-Gac-041967	Gasterosteus aculeatus	91.71	0.00e+00	706.00
IUUC-Hsa-045700	Homo sapiens	96.45	0.00e+00	740.00
IUUC-Hvu-047692	Hordeum vulgare	58.22	9.00e-123	432.00
IUUC-Itr-049082	Ictidomys tridecemlineatus	98.59	0.00e+00	731.00
IUUC-Lch-050435	Latimeria chalumnae	96.91	0.00e+00	707.00
IUUC-Loc-051968	Lepisosteus oculatus	93.44	0.00e+00	726.00
IUUC-Lma-053300	Leptosphaeria maculans	46.73	3.00e-78	285.00
IUUC-Laf-053887	Loxodonta africana	96.45	0.00e+00	740.00
IUUC-Mcc-055701	Macaca mulatta	98.06	0.00e+00	740.00
IUUC-Mor-057072	Magnaporthe oryzae	43.97	4.00e-75	275.00
IUUC-Mpo-057424	Magnaporthe poae	43.69	8.00e-75	274.00
IUUC-Mga-059195	Meleagris gallopavo	99.72	0.00e+00	753.00
IUUC-Mmr-060751	Microcebus murinus	96.45	0.00e+00	740.00
IUUC-Mdo-062735	Monodelphis domestica	95.86	0.00e+00	723.00
IUUC-Mmu-063263	Mus musculus	97.22	0.00e+00	735.00
IUUC-Mlu-068128	Myotis lucifugus	98.87	0.00e+00	731.00
IUUC-Nfi-068611	Neosartorya fischeri	49.16	2.00e-77	283.00
IUUC-Ncr-068699	Neurospora crassa	43.97	5.00e-75	275.00
IUUC-Nle-069767	Nomascus leucogenys	98.59	0.00e+00	731.00
IUUC-Ont-072658	Oreochromis niloticus	91.99	0.00e+00	707.00
IUUC-Oan-073372	Ornithorhynchus anatinus	98.02	0.00e+00	728.00
IUUC-Ocu-074322	Oryctolagus cuniculus	97.50	0.00e+00	732.00
IUUC-Ola-087418	Oryzias latipes	91.99	0.00e+00	708.00
IUUC-Oga-088298	Otolemur garnettii	98.87	0.00e+00	731.00
IUUC-Oar-090269	Ovis aries	97.78	0.00e+00	740.00
IUUC-Ptr-090467	Pan troglodytes	96.45	0.00e+00	740.00
IUUC-Pan-092437	Papio anubis	96.16	0.00e+00	731.00
IUUC-Psi-092993	Pelodiscus sinensis	98.59	0.00e+00	730.00
IUUC-Pno-095044	Phaeosphaeria nodorum	47.85	7.00e-78	285.00
IUUC-Pfo-097052	Poecilia formosa	91.99	0.00e+00	707.00
IUUC-Pab-097797	Pongo abelii	96.45	0.00e+00	740.00
IUUC-Pca-100835	Procavia capensis	90.18	1.00e-174	604.00
IUUC-Pgr-103306	Puccinia graminis	52.98	4.00e-95	343.00
IUUC-Pyt-104709	Pyrenophora triticirepentis	48.04	2.00e-78	286.00
IUUC-Rno-106060	Rattus norvegicus	98.02	0.00e+00	725.00
IUUC-Sce-106196	Saccharomyces cerevisiae	38.59	9.00e-56	211.00
IUUC-Sha-107087	Sarcophilus harrisii	96.45	0.00e+00	740.00
IUUC-Sja-107684	Schizosaccharomyces japonicus	45.73	1.00e-67	250.00
IUUC-Spo-108095	Schizosaccharomyces pombe	47.24	3.00e-76	278.00
IUUC-Sar-113216	Sorex araneus	98.31	0.00e+00	722.00
IUUC-Sre-115197	Sporisorium reilianum	50.18	6.00e-81	295.00
IUUC-Ssc-116321	Sus scrofa	96.94	0.00e+00	729.00
IUUC-Tgu-117482	Taeniopygia guttata	97.75	0.00e+00	711.00
IUUC-Tru-118613	Takifugu rubripes	91.71	0.00e+00	706.00
IUUC-Tsy-119520	Tarsius syrichta	88.24	8.00e-130	455.00
IUUC-Tni-120293	Tetraodon nigroviridis	91.71	0.00e+00	706.00
IUUC-Tre-122226	Trichoderma reesei	45.03	3.00e-75	275.00
IUUC-Tvi-122330	Trichoderma virens	45.03	6.00e-75	275.00
IUUC-Tbe-127783	Tupaia belangeri	97.74	0.00e+00	712.00
IUUC-Ttr-129083	Tursiops truncatus	96.17	0.00e+00	739.00
IUUC-Vda-129736	Verticillium dahliae	38.76	5.00e-58	218.00
IUUC-Vpa-130391	Vicugna pacos	94.33	0.00e+00	693.00
IUUC-Xtr-132464	Xenopus tropicalis	98.59	0.00e+00	705.00
IUUC-Xma-133475	Xiphophorus maculatus	91.99	0.00e+00	707.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence