iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-006841

UUCD1 version

UUC-ArT-01023

Ensembl Protein ID

AT4G27470.1

UniProt Accession

Q8GUK7; Q9SZS2; RMA3_ARATH

Genbank Protein ID

AAY57610.1; CAB43879.1; CAB81397.1; AEE85346.1; AAO00789.1; AAP13393.1

Protein Name

E3 ubiquitin-protein ligase RMA3; Protein RING membrane-anchor 3; RING-type E3 ubiquitin transferase RMA3

Genbank Nucleotide ID

DQ059124; AL078467; AL161571; CP002687; BT002429; BT006285

Gene Name

RMA3; At4g27470; F27G19.70

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT4G27470	AT4G27470.1	AT4G27470.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	16339806

Classification

Family	E-value	Score	Start	End
E3 activity/RING/U-box	3.30e-06	28.0	41	103
E3 activity/RING/RING	1.90e-07	32.3	44	92

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 5    eflCpIslelMrdPvvlpsGitydrssIekwl.........asggk...tcPvtrqplteedlvPn 58
            f C I l+  +dPvv+ +G+ +   +I kwl         +   +    cPv+++ +t ++lvP 
   Q: 41   CFDCNICLDTAHDPVVTLCGHLFCWPCIYKWLhvqlssvsvD---QhqnNCPVCKSNITITSLVPL 103
           599*****************************7776665543...04569**************96 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw....pglknssskefrCPlCr 46
           C iCl+   d p+v+ CgH+f+  C++kw      + ++ + + +CP+C+
   Q: 44   CNICLDTAHD-PVVTLCGHLFCWPCIYKWlhvqLSSVSVDQHQNNCPVCK 92
           99********.9999**************9976555555667778****7 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

E3 ubiquitin-protein ligase.

Protein Sequence
(Fasta)

MEGNFFIRSD AQRAHDNGFI AKQKPNLTTA PTAGQANESG CFDCNICLDT AHDPVVTLCG 60
HLFCWPCIYK WLHVQLSSVS VDQHQNNCPV CKSNITITSL VPLYGRGMSS PSSTFGSKKQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACAAAAA ACTGCCCCCA CCGTCGTTGT CTAAAAATAT ATTATATTAA AATAATTGGC 60
AAAGACGAAG ACGAAGCACC CTCATCTCCG TCGTTTGTCT TTAAAACCTT TTGCCATTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00097--zf-C3HC4

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0044390--F:ubiquitin-like protein conjugating enzyme binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0071712--P:ER-associated misfolded protein catabolic process
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ath:AT4G27470

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000767	Aegilops tauschii	50.42	2.00e-27	115.00
IUUC-Aly-006090	Arabidopsis lyrata	95.63	3.00e-132	463.00
IUUC-Bdi-014665	Brachypodium distachyon	54.46	5.00e-26	110.00
IUUC-Bol-015969	Brassica oleracea	82.33	1.00e-107	381.00
IUUC-Bra-017099	Brassica rapa	81.55	1.00e-106	378.00
IUUC-Gma-044283	Glycine max	45.49	5.00e-42	163.00
IUUC-Hvu-047276	Hordeum vulgare	37.31	8.00e-28	116.00
IUUC-Lpe-051528	Leersia perrieri	38.64	1.00e-25	110.00
IUUC-Mac-065357	Musa acuminata	51.35	2.00e-26	111.00
IUUC-Obr-076866	Oryza brachyantha	38.73	2.00e-25	108.00
IUUC-Olo-081070	Oryza longistaminata	37.57	2.00e-24	105.00
IUUC-Pop-099944	Populus trichocarpa	48.18	1.00e-54	205.00
IUUC-Sit-110015	Setaria italica	51.55	7.00e-26	110.00
IUUC-Sly-111102	Solanum lycopersicum	38.74	8.00e-38	149.00
IUUC-Stu-112640	Solanum tuberosum	40.66	1.00e-42	165.00
IUUC-Tca-121161	Theobroma cacao	47.37	4.00e-53	200.00
IUUC-Tae-124608	Triticum aestivum	50.42	1.00e-27	115.00
IUUC-Tur-126644	Triticum urartu	49.58	2.00e-26	113.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence