iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000023327.3	ENSXETT00000063988.1	ENSXETP00000058726.1
ENSXETG00000023327.3	ENSXETT00000050396.2	ENSXETP00000050396.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.10e-09	37.9	291	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC+e++ +g + lpC+H+fh++Cl  w       +++++CP+Cr
   Q: 291  CIICREEMVTGAKRLPCNHIFHTSCLRSW------FQRQQTCPTCR 330
           ********99999****************......**********8 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

KMRTAVMTGA SLALTAAVVA HAYFLKNQFY PTVVYLTKSS PSMAVLYIQA FVLVFLLGKF 60
MGKVFFGQLR AAEMEHLLER SWYAVTETCL AFTVFRDDFS PRFVALFTLL LFLKCFHWLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGGCAAG AGAGAAGTGG GTAAGTGGAT AGCTGTCATC ACCATGGCTT GGTAACTGGG 60
GGTAAGGCAC TCTCGGTGGG GTGAATTAGT AAGGGTACAA GGAGGAGAGT TTGTGAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR032832--E3_lig_synoviolin/Hrd1
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0044322--C:endoplasmic reticulum quality control compartment
GO:0000836--C:Hrd1p ubiquitin ligase complex
GO:0016021--C:integral component of membrane
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0051082--F:unfolded protein binding
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	37.50	5.00e-48	184.00
IUUC-Aml-001539	Ailuropoda melanoleuca	94.05	0.00e+00	652.00
IUUC-Atr-002892	Amborella trichopoda	44.31	5.00e-78	285.00
IUUC-Apl-004003	Anas platyrhynchos	91.53	3.00e-63	232.00
IUUC-Aca-004799	Anolis carolinensis	94.36	0.00e+00	632.00
IUUC-Aly-006352	Arabidopsis lyrata	42.81	8.00e-73	267.00
IUUC-Ath-006773	Arabidopsis thaliana	42.81	2.00e-72	266.00
IUUC-Ago-007894	Ashbya gossypii	26.27	1.00e-16	81.30
IUUC-Acl-008041	Aspergillus clavatus	31.62	4.00e-57	216.00
IUUC-Afl-008427	Aspergillus flavus	31.56	1.00e-50	194.00
IUUC-Afu-009023	Aspergillus fumigatus	31.27	1.00e-56	214.00
IUUC-Ani-009133	Aspergillus nidulans	32.17	6.00e-60	225.00
IUUC-Ang-009612	Aspergillus niger	35.65	2.00e-56	213.00
IUUC-Aor-010045	Aspergillus oryzae	31.85	5.00e-59	222.00
IUUC-Ate-010533	Aspergillus terreus	32.77	2.00e-58	220.00
IUUC-Ame-011083	Astyanax mexicanus	91.48	1.00e-174	605.00
IUUC-Bgr-012122	Blumeria graminis	27.92	1.00e-46	181.00
IUUC-Bta-013375	Bos taurus	93.99	0.00e+00	648.00
IUUC-Bci-013675	Botrytis cinerea	37.25	3.00e-24	107.00
IUUC-Bdi-015070	Brachypodium distachyon	42.51	2.00e-67	249.00
IUUC-Bol-015674	Brassica oleracea	43.03	1.00e-72	266.00
IUUC-Bra-017516	Brassica rapa	41.04	3.00e-69	255.00
IUUC-Cel-018422	Caenorhabditis elegans	57.31	8.00e-118	417.00
IUUC-Cja-019779	Callithrix jacchus	91.39	7.00e-178	617.00
IUUC-Cfa-020189	Canis familiaris	93.99	0.00e+00	648.00
IUUC-Cpo-022209	Cavia porcellus	93.75	0.00e+00	648.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	39.56	1.00e-62	233.00
IUUC-Csa-023571	Chlorocebus sabaeus	93.99	0.00e+00	647.00
IUUC-Cho-024889	Choloepus hoffmanni	84.48	3.00e-169	588.00
IUUC-Csv-026160	Ciona savignyi	61.21	7.00e-125	440.00
IUUC-Cne-027002	Cryptococcus neoformans	39.18	7.00e-72	265.00
IUUC-Cme-027285	Cyanidioschyzon merolae	35.98	7.00e-49	188.00
IUUC-Dre-027999	Danio rerio	91.48	3.00e-176	611.00
IUUC-Dno-029250	Dasypus novemcinctus	93.75	0.00e+00	651.00
IUUC-Dor-030718	Dipodomys ordii	89.29	3.00e-177	614.00
IUUC-Dse-031498	Dothistroma septosporum	34.76	2.00e-28	120.00
IUUC-Dme-031969	Drosophila melanogaster	64.85	2.00e-137	482.00
IUUC-Eca-033258	Equus caballus	94.05	0.00e+00	652.00
IUUC-Fca-035980	Felis catus	93.71	0.00e+00	647.00
IUUC-Fal-037554	Ficedula albicollis	67.13	8.00e-97	347.00
IUUC-Fox-037902	Fusarium oxysporum	30.85	5.00e-54	205.00
IUUC-Fso-038418	Fusarium solani	31.17	6.00e-50	192.00
IUUC-Gmo-039288	Gadus morhua	88.99	8.00e-174	603.00
IUUC-Ggr-040076	Gaeumannomyces graminis	38.03	1.00e-26	115.00
IUUC-Gga-040347	Gallus gallus	93.48	1.00e-74	271.00
IUUC-Gac-042347	Gasterosteus aculeatus	90.85	8.00e-175	606.00
IUUC-Gma-043917	Glycine max	43.64	1.00e-74	273.00
IUUC-Ggo-044858	Gorilla gorilla	94.03	0.00e+00	650.00
IUUC-Hsa-046412	Homo sapiens	94.05	0.00e+00	652.00
IUUC-Hvu-047279	Hordeum vulgare	42.73	3.00e-65	242.00
IUUC-Itr-048924	Ictidomys tridecemlineatus	93.99	0.00e+00	647.00
IUUC-Kpa-049117	Komagataella pastoris	29.55	3.00e-29	122.00
IUUC-Lch-049533	Latimeria chalumnae	54.50	7.00e-57	214.00
IUUC-Lpe-051229	Leersia perrieri	32.17	1.00e-30	127.00
IUUC-Loc-052843	Lepisosteus oculatus	90.23	6.00e-114	402.00
IUUC-Lma-052997	Leptosphaeria maculans	32.55	1.00e-58	221.00
IUUC-Laf-053482	Loxodonta africana	93.99	0.00e+00	645.00
IUUC-Mcc-055075	Macaca mulatta	94.05	0.00e+00	653.00
IUUC-Meu-056683	Macropus eugenii	93.92	2.00e-147	515.00
IUUC-Mor-057082	Magnaporthe oryzae	31.59	1.00e-54	208.00
IUUC-Mpo-057573	Magnaporthe poae	31.51	3.00e-49	189.00
IUUC-Mtr-058601	Medicago truncatula	43.71	2.00e-78	286.00
IUUC-Mla-059168	Melampsora laricipopulina	38.89	6.00e-75	275.00
IUUC-Mga-059510	Meleagris gallopavo	97.59	9.00e-46	176.00
IUUC-Mvi-060515	Microbotryum violaceum	40.17	4.00e-65	242.00
IUUC-Mmr-060922	Microcebus murinus	94.03	0.00e+00	649.00
IUUC-Mdo-062491	Monodelphis domestica	93.43	0.00e+00	645.00
IUUC-Mmu-063770	Mus musculus	94.01	0.00e+00	647.00
IUUC-Mac-064789	Musa acuminata	42.81	1.00e-77	283.00
IUUC-Mpu-066107	Mustela putorius furo	94.10	0.00e+00	657.00
IUUC-Mlu-067918	Myotis lucifugus	92.60	3.00e-171	595.00
IUUC-Nfi-068389	Neosartorya fischeri	31.01	9.00e-56	211.00
IUUC-Ncr-068742	Neurospora crassa	33.33	2.00e-51	197.00
IUUC-Nle-069139	Nomascus leucogenys	94.05	0.00e+00	652.00
IUUC-Opr-070898	Ochotona princeps	91.04	5.00e-113	401.00
IUUC-Ont-071991	Oreochromis niloticus	88.15	4.00e-177	614.00
IUUC-Ocu-074065	Oryctolagus cuniculus	93.73	0.00e+00	647.00
IUUC-Oba-075221	Oryza barthii	41.32	1.00e-64	239.00
IUUC-Obr-076914	Oryza brachyantha	42.57	2.00e-61	229.00
IUUC-Ogu-078124	Oryza glumaepatula	41.32	2.00e-64	239.00
IUUC-Oin-080013	Oryza indica	39.34	1.00e-60	226.00
IUUC-Olo-080247	Oryza longistaminata	40.19	4.00e-58	218.00
IUUC-Ome-081769	Oryza meridionalis	41.62	3.00e-67	249.00
IUUC-Oni-082946	Oryza nivara	41.32	2.00e-64	239.00
IUUC-Opu-083268	Oryza punctata	35.43	4.00e-48	186.00
IUUC-Oru-085114	Oryza rufipogon	41.32	2.00e-64	239.00
IUUC-Osa-085829	Oryza sativa	41.92	4.00e-67	248.00
IUUC-Ola-087449	Oryzias latipes	90.79	5.00e-174	604.00
IUUC-Olu-087894	Ostreococcus lucimarinus	42.34	2.00e-71	262.00
IUUC-Oga-089036	Otolemur garnettii	93.99	0.00e+00	646.00
IUUC-Oar-089715	Ovis aries	94.05	0.00e+00	652.00
IUUC-Ptr-091000	Pan troglodytes	93.99	0.00e+00	646.00
IUUC-Pan-092187	Papio anubis	94.05	0.00e+00	651.00
IUUC-Psi-093377	Pelodiscus sinensis	95.25	2.00e-178	618.00
IUUC-Pma-094759	Petromyzon marinus	90.14	3.00e-77	281.00
IUUC-Pno-094883	Phaeosphaeria nodorum	32.09	2.00e-56	213.00
IUUC-Ppa-095684	Physcomitrella patens	44.41	1.00e-71	263.00
IUUC-Pfo-096861	Poecilia formosa	88.10	2.00e-178	619.00
IUUC-Pab-098030	Pongo abelii	94.05	0.00e+00	651.00
IUUC-Pop-099245	Populus trichocarpa	43.03	5.00e-79	288.00
IUUC-Pca-100191	Procavia capensis	90.56	7.00e-179	620.00
IUUC-Ppe-101829	Prunus persica	43.33	4.00e-78	285.00
IUUC-Pva-102689	Pteropus vampyrus	94.05	0.00e+00	653.00
IUUC-Pgr-103286	Puccinia graminis	37.20	1.00e-70	261.00
IUUC-Ptt-103919	Puccinia triticina	36.60	2.00e-69	256.00
IUUC-Pte-104372	Pyrenophora teres	32.66	1.00e-61	231.00
IUUC-Pyt-104456	Pyrenophora triticirepentis	32.41	2.00e-59	223.00
IUUC-Rno-105723	Rattus norvegicus	93.99	0.00e+00	646.00
IUUC-Sce-106348	Saccharomyces cerevisiae	25.88	3.00e-21	96.30
IUUC-Sha-107300	Sarcophilus harrisii	93.26	1.00e-149	523.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	27.52	2.00e-36	146.00
IUUC-Spo-108308	Schizosaccharomyces pombe	29.55	1.00e-37	151.00
IUUC-Ssl-108558	Sclerotinia sclerotiorum	37.25	2.00e-24	107.00
IUUC-Smo-109123	Selaginella moellendorffii	46.37	8.00e-73	267.00
IUUC-Sit-110276	Setaria italica	42.51	4.00e-69	255.00
IUUC-Sly-111819	Solanum lycopersicum	43.56	1.00e-69	257.00
IUUC-Stu-112048	Solanum tuberosum	41.92	8.00e-75	274.00
IUUC-Sbi-114027	Sorghum bicolor	41.32	3.00e-75	275.00
IUUC-Sre-115212	Sporisorium reilianum	36.18	5.00e-62	232.00
IUUC-Ssc-116323	Sus scrofa	93.99	0.00e+00	648.00
IUUC-Tgu-117156	Taeniopygia guttata	89.61	2.00e-38	149.00
IUUC-Tru-118045	Takifugu rubripes	88.02	6.00e-177	613.00
IUUC-Tsy-118823	Tarsius syrichta	82.02	7.00e-151	526.00
IUUC-Tni-120106	Tetraodon nigroviridis	88.54	1.00e-127	449.00
IUUC-Tca-121462	Theobroma cacao	44.91	9.00e-78	284.00
IUUC-Tre-122204	Trichoderma reesei	38.73	3.00e-27	117.00
IUUC-Tvi-122550	Trichoderma virens	30.42	3.00e-52	200.00
IUUC-Tae-125239	Triticum aestivum	43.69	4.00e-68	251.00
IUUC-Tur-126538	Triticum urartu	37.69	3.00e-46	179.00
IUUC-Tme-127197	Tuber melanosporum	40.17	8.00e-69	255.00
IUUC-Tbe-127385	Tupaia belangeri	85.67	2.00e-169	589.00
IUUC-Ttr-128795	Tursiops truncatus	94.03	0.00e+00	650.00
IUUC-Uma-129401	Ustilago maydis	34.75	4.00e-52	199.00
IUUC-Vda-129968	Verticillium dahliae	36.36	2.00e-23	104.00
IUUC-Vvi-130944	Vitis vinifera	45.51	3.00e-76	278.00
IUUC-Xma-133488	Xiphophorus maculatus	88.69	4.00e-179	621.00
IUUC-Yli-134552	Yarrowia lipolytica	26.01	1.00e-34	140.00
IUUC-Zma-135530	Zea mays	43.46	1.00e-65	244.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence