iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074844

Ensembl Protein ID

ENSOCUP00000011496.3

UniProt Accession

G1T589; G1T589_RABIT

Genbank Protein ID

ENSOCUP00000011496

Protein Name

Autophagy protein 5

Genbank Nucleotide ID

AAGW02029553

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000013358.3	ENSOCUT00000013357.3	ENSOCUP00000011496.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/Other	23.74	1.70e-02	33.90	IUUC-Sce-106216

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Oryctolagus cuniculus

Functional Description
(View)

Involved in autophagic vesicle formation.

Protein Sequence
(Fasta)

MTDDKDVLRD VWFGRIPTCF TLCQDEITER EAEPYYNFPE KDLLHCPSKD AIEAHFMSCM 60
KEADALKHKS QVINEMQKKD HKQLWMGLQN DRFDQFWAIN RKLMEYPAEE SGFRYIPFRI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTGGATGA CCTAGAGGAG AGGAAGAGGA AGGTTGCCAC CAAGCTCTCG GGAGGCAACG 60
TCTCATTTTA AAAACTCGGT TCTTGGGGTA CCGTTACTTT AACTTCCCAC ACACCAGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0001974--P:blood vessel remodeling
GO:0019725--P:cellular homeostasis
GO:0071500--P:cellular response to nitrosative stress
GO:0009267--P:cellular response to starvation
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000583	Aegilops tauschii	31.37	1.70e-01	31.60
IUUC-Aml-002403	Ailuropoda melanoleuca	94.25	2.00e-95	342.00
IUUC-Atr-002645	Amborella trichopoda	43.75	3.00e-03	35.80
IUUC-Apl-003611	Anas platyrhynchos	86.63	5.00e-90	323.00
IUUC-Aca-004411	Anolis carolinensis	88.00	7.00e-89	320.00
IUUC-Aly-005636	Arabidopsis lyrata	21.30	1.00e-08	53.90
IUUC-Ath-006959	Arabidopsis thaliana	22.17	5.00e-09	55.10
IUUC-Ago-007978	Ashbya gossypii	28.97	1.50e-01	30.00
IUUC-Acl-008328	Aspergillus clavatus	20.83	4.00e-06	45.10
IUUC-Afl-008638	Aspergillus flavus	20.53	1.00e-05	43.90
IUUC-Afu-009042	Aspergillus fumigatus	20.79	3.00e-05	42.70
IUUC-Aor-009889	Aspergillus oryzae	20.53	1.00e-05	43.90
IUUC-Ame-011644	Astyanax mexicanus	55.38	1.00e-16	77.40
IUUC-Bgr-012153	Blumeria graminis	29.87	3.00e-11	62.40
IUUC-Bta-012360	Bos taurus	91.07	2.00e-26	110.00
IUUC-Bci-013723	Botrytis cinerea	25.00	2.00e-08	52.80
IUUC-Bdi-014520	Brachypodium distachyon	18.37	1.00e-03	37.70
IUUC-Bol-016053	Brassica oleracea	21.21	3.00e-09	55.80
IUUC-Bra-017072	Brassica rapa	22.08	2.00e-09	56.20
IUUC-Cel-018529	Caenorhabditis elegans	35.20	7.00e-22	97.40
IUUC-Cja-019569	Callithrix jacchus	96.51	4.00e-98	350.00
IUUC-Cfa-020473	Canis familiaris	96.51	1.00e-97	349.00
IUUC-Cpo-021421	Cavia porcellus	93.60	6.00e-96	343.00
IUUC-Csa-024197	Chlorocebus sabaeus	95.93	2.00e-97	348.00
IUUC-Cho-024521	Choloepus hoffmanni	94.77	3.00e-96	344.00
IUUC-Cin-025119	Ciona intestinalis	43.71	1.00e-33	136.00
IUUC-Csv-026192	Ciona savignyi	43.37	5.00e-34	137.00
IUUC-Cgl-026686	Colletotrichum gloeosporioides	22.40	2.00e-08	52.80
IUUC-Dre-028466	Danio rerio	78.49	3.00e-79	288.00
IUUC-Dse-031228	Dothistroma septosporum	26.34	2.00e-13	69.70
IUUC-Dme-031703	Drosophila melanogaster	49.40	4.00e-42	164.00
IUUC-Ete-032482	Echinops telfairi	94.19	2.00e-95	341.00
IUUC-Eca-034036	Equus caballus	94.77	5.00e-97	347.00
IUUC-Eeu-035235	Erinaceus europaeus	91.07	3.00e-26	112.00
IUUC-Fca-036263	Felis catus	95.35	4.00e-97	347.00
IUUC-Fal-037064	Ficedula albicollis	87.21	1.00e-90	325.00
IUUC-Fox-037813	Fusarium oxysporum	27.11	5.00e-11	61.20
IUUC-Fso-038139	Fusarium solani	27.88	4.00e-12	65.10
IUUC-Gmo-039509	Gadus morhua	80.67	2.00e-56	211.00
IUUC-Ggr-040111	Gaeumannomyces graminis	25.93	7.00e-11	61.20
IUUC-Gga-040517	Gallus gallus	87.79	2.00e-90	325.00
IUUC-Gac-042270	Gasterosteus aculeatus	70.14	4.00e-60	224.00
IUUC-Gma-044400	Glycine max	25.71	2.00e-04	39.30
IUUC-Ggo-045048	Gorilla gorilla	95.93	6.00e-97	346.00
IUUC-Hsa-046744	Homo sapiens	96.51	2.00e-97	348.00
IUUC-Kpa-049174	Komagataella pastoris	27.56	6.00e-04	38.10
IUUC-Lch-049475	Latimeria chalumnae	86.05	2.00e-87	315.00
IUUC-Lpe-051283	Leersia perrieri	32.43	1.20e-01	32.30
IUUC-Loc-052446	Lepisosteus oculatus	80.81	4.00e-83	300.00
IUUC-Lma-053278	Leptosphaeria maculans	21.31	4.00e-09	55.10
IUUC-Laf-054020	Loxodonta africana	94.25	6.00e-96	343.00
IUUC-Mcc-055176	Macaca mulatta	96.51	2.00e-97	348.00
IUUC-Mor-057164	Magnaporthe oryzae	24.22	8.00e-10	57.80
IUUC-Mpo-057428	Magnaporthe poae	25.31	8.00e-11	60.50
IUUC-Mtr-058424	Medicago truncatula	22.86	1.00e-03	36.60
IUUC-Mla-058872	Melampsora laricipopulina	24.86	2.00e-10	60.50
IUUC-Mga-059859	Meleagris gallopavo	87.79	2.00e-90	325.00
IUUC-Mmr-061482	Microcebus murinus	96.51	1.00e-97	349.00
IUUC-Mdo-062371	Monodelphis domestica	91.86	1.00e-94	338.00
IUUC-Mmu-063139	Mus musculus	93.02	5.00e-96	343.00
IUUC-Mac-065332	Musa acuminata	26.25	1.00e-03	37.40
IUUC-Mpu-066783	Mustela putorius furo	95.93	2.00e-97	348.00
IUUC-Mlu-068165	Myotis lucifugus	93.68	1.00e-94	338.00
IUUC-Nfi-068578	Neosartorya fischeri	22.06	4.00e-06	45.40
IUUC-Ncr-068636	Neurospora crassa	23.67	9.00e-08	50.80
IUUC-Nle-069740	Nomascus leucogenys	95.93	3.00e-97	347.00
IUUC-Opr-070802	Ochotona princeps	94.64	7.00e-27	114.00
IUUC-Ont-072222	Oreochromis niloticus	74.42	3.00e-78	284.00
IUUC-Oan-072760	Ornithorhynchus anatinus	88.30	2.00e-47	181.00
IUUC-Oba-075834	Oryza barthii	34.38	1.40e-01	30.40
IUUC-Obr-076230	Oryza brachyantha	32.43	3.30e-02	32.30
IUUC-Ogl-077554	Oryza glaberrima	34.38	1.40e-01	30.40
IUUC-Ogu-078687	Oryza glumaepatula	34.38	1.60e-01	30.40
IUUC-Oin-079677	Oryza indica	34.38	1.50e-01	30.40
IUUC-Olo-081078	Oryza longistaminata	34.38	2.60e-01	30.40
IUUC-Oni-082050	Oryza nivara	34.38	1.40e-01	30.40
IUUC-Opu-083609	Oryza punctata	24.68	3.00e-04	39.30
IUUC-Oru-085057	Oryza rufipogon	34.38	1.40e-01	30.40
IUUC-Osa-085917	Oryza sativa	34.38	1.40e-01	30.40
IUUC-Ola-087032	Oryzias latipes	75.58	3.00e-78	284.00
IUUC-Olu-087877	Ostreococcus lucimarinus	27.06	1.00e-02	32.30
IUUC-Oga-088468	Otolemur garnettii	94.25	6.00e-96	343.00
IUUC-Oar-089751	Ovis aries	94.19	3.00e-96	344.00
IUUC-Ptr-091064	Pan troglodytes	96.51	2.00e-97	348.00
IUUC-Pan-092505	Papio anubis	94.83	1.00e-95	342.00
IUUC-Psi-093086	Pelodiscus sinensis	89.02	7.00e-92	330.00
IUUC-Pno-094825	Phaeosphaeria nodorum	24.20	4.00e-09	55.10
IUUC-Ppa-095419	Physcomitrella patens	36.96	5.00e-04	38.90
IUUC-Pfo-096224	Poecilia formosa	74.42	2.00e-77	281.00
IUUC-Pab-098501	Pongo abelii	95.93	3.00e-97	347.00
IUUC-Pop-099243	Populus trichocarpa	21.28	4.00e-07	48.90
IUUC-Ppe-101255	Prunus persica	20.47	2.00e-06	46.60
IUUC-Pva-102828	Pteropus vampyrus	94.19	7.00e-96	343.00
IUUC-Pgr-103672	Puccinia graminis	27.01	2.00e-10	60.10
IUUC-Ptt-104013	Puccinia triticina	23.62	5.00e-07	48.50
IUUC-Pyt-104615	Pyrenophora triticirepentis	23.76	2.00e-11	62.80
IUUC-Rno-106089	Rattus norvegicus	91.76	6.00e-94	336.00
IUUC-Sce-106216	Saccharomyces cerevisiae	23.74	9.00e-03	33.90
IUUC-Sha-106484	Sarcophilus harrisii	92.44	3.00e-95	341.00
IUUC-Sja-107699	Schizosaccharomyces japonicus	25.75	4.00e-12	64.70
IUUC-Spo-108177	Schizosaccharomyces pombe	26.67	4.00e-10	58.20
IUUC-Ssl-108475	Sclerotinia sclerotiorum	24.02	7.00e-08	50.80
IUUC-Smo-109473	Selaginella moellendorffii	20.55	2.00e-03	36.60
IUUC-Sit-110736	Setaria italica	24.47	1.00e-04	40.80
IUUC-Sly-111657	Solanum lycopersicum	37.04	3.00e-04	39.70
IUUC-Sar-113050	Sorex araneus	72.67	1.00e-68	252.00
IUUC-Sbi-114258	Sorghum bicolor	27.08	9.80e-02	31.20
IUUC-Sre-114902	Sporisorium reilianum	36.23	6.00e-06	45.40
IUUC-Ssc-116166	Sus scrofa	83.72	1.00e-85	309.00
IUUC-Tgu-116814	Taeniopygia guttata	86.05	2.00e-89	321.00
IUUC-Tru-118172	Takifugu rubripes	76.30	3.00e-77	281.00
IUUC-Tsy-119010	Tarsius syrichta	73.84	2.00e-69	255.00
IUUC-Tni-120397	Tetraodon nigroviridis	73.83	9.00e-45	172.00
IUUC-Tca-121283	Theobroma cacao	21.79	4.00e-07	48.90
IUUC-Tvi-122545	Trichoderma virens	22.89	1.00e-08	53.50
IUUC-Tur-126407	Triticum urartu	30.56	2.80e-01	29.30
IUUC-Tme-126913	Tuber melanosporum	27.78	3.00e-17	82.00
IUUC-Tbe-127738	Tupaia belangeri	88.95	4.00e-89	320.00
IUUC-Ttr-128528	Tursiops truncatus	95.35	1.00e-97	348.00
IUUC-Uma-129625	Ustilago maydis	32.81	1.00e-03	37.70
IUUC-Vda-129906	Verticillium dahliae	24.84	6.00e-09	54.30
IUUC-Vpa-130223	Vicugna pacos	92.44	2.00e-90	325.00
IUUC-Vvi-131617	Vitis vinifera	43.40	3.00e-04	39.70
IUUC-Xtr-132288	Xenopus tropicalis	82.56	2.00e-83	301.00
IUUC-Xma-134214	Xiphophorus maculatus	78.89	2.00e-41	161.00
IUUC-Yli-134377	Yarrowia lipolytica	24.85	1.00e-10	60.10
IUUC-Zma-135108	Zea mays	26.09	4.00e-02	32.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence