iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cin-025482

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

EAAA01000285

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCING00000007969.4	ENSCINT00000016316.3	ENSCINP00000016316.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.90e-86	290.3	129	532

Active Site

Position(s)	Description	Evidence
500	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp............................ 65
            ++ lev+++gE g++l G+t+ef++l+s+elq+++l+l++ ++n+++  q  + + ++ +                            
   Q: 129  TRSLLEVQYEGEVGTGL-GPTLEFYTLVSHELQRSNLSLWRSDDNSNSVDQSHNIEQTSAKkmlkklseiveeeqfnspvametsfvhs 216
           567899***********.**********************999985555444444444444578889********************** PP
   S: 66   ...................ehlklFeflGrllgkalqdgrlldlplsksfyklllgk..klsledleevdpelykslkeikena..... 128
                              +  + F+flGr+ +ka++dgrl+d+pls  +yk  l++   +++ dle+vdp +  + +++k++      
   Q: 217  pvglyplpigrtsklgpiaKACSKFRFLGRFFAKAVMDGRLVDVPLSMICYKWFLSQehTITWLDLEQVDPGMSLTFNKLKRLLhqrlt 305
           ********************************************************9556999*********99998888888744455 PP
   S: 129  ....es...dieelgldltfsvseei............lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfn 198
               +s   + +  ++++                    l+   + eL+ +G++++  ++N+++Y +l++ ++l eg+++q++a+r+Gf+
   Q: 306  ieqqQSdemEEKINAVTM-------DgcrledlgldflLPGFPNIELMKSGAKTSLSINNLDKYLNLIAYWTLSEGVRQQLDAMRDGFQ 387
           543311322222222233.......13334445888889************************************************** PP
   S: 199  eviplellslFteeelellicGe..eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkpr 285
           +v+pl+ +++F +eel++l cG   + ++  +l++ ++ ++gy++ds++++++++vl++ ++ e++afLqFvTgs+ lP+gG+++l+p 
   Q: 388  SVFPLQAIDYFFPEELDQLFCGAryQPWSERELADSCRTDHGYNHDSETVKTLFRVLSQYDAAEQRAFLQFVTGSPHLPVGGLRSLHPP 476
           **********************9788899999********************************************************* PP
   S: 286  lfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           l+++rk      +sd+ lPs++TC+nyLkLPeYs++++++e+L+ A +e+ k+F l
   Q: 477  LTIVRKtceenMTSDSYLPSVMTCVNYLKLPEYSNESVMRERLQKAAQEGqKSFLL 532
           *********988899***********************************999976 PP

Organism

Ciona intestinalis

Protein Sequence
(Fasta)

PLLPISDFVN TKLSAKCSRQ LQDPLMIMTG ELPSWLSEIA HACPFVLPFD IRQLLFRVVS 60
FDRDRAMQHL LDSGLLSDVN TASSSAGTGS LSQDSNNRFM PKIEKKKCSV KRENLLQQAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATTCGGCTT GACACGATAT TGGCACACAC TCTACACACC CAGTATTCTA TCAACCGATC 60
GACCGTTGCT CCCAATATCG GACTTCGTCA ACACAAAACT ATCAGCTAAA TGTAGCCGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000060	Aegilops tauschii	38.04	1.00e-97	350.00
IUUC-Aml-001502	Ailuropoda melanoleuca	51.21	3.00e-160	558.00
IUUC-Atr-002821	Amborella trichopoda	37.00	3.00e-97	349.00
IUUC-Apl-003531	Anas platyrhynchos	48.88	3.00e-146	512.00
IUUC-Aly-005962	Arabidopsis lyrata	38.62	1.00e-99	357.00
IUUC-Ath-006636	Arabidopsis thaliana	38.98	9.00e-103	367.00
IUUC-Ago-007875	Ashbya gossypii	32.70	9.00e-71	261.00
IUUC-Acl-008242	Aspergillus clavatus	37.38	4.00e-99	355.00
IUUC-Afl-008736	Aspergillus flavus	37.38	6.00e-98	352.00
IUUC-Afu-008812	Aspergillus fumigatus	37.24	7.00e-100	358.00
IUUC-Ani-009407	Aspergillus nidulans	35.82	3.00e-93	336.00
IUUC-Ang-009763	Aspergillus niger	35.20	4.00e-87	315.00
IUUC-Aor-009941	Aspergillus oryzae	37.20	4.00e-98	352.00
IUUC-Ate-010459	Aspergillus terreus	33.26	1.00e-74	274.00
IUUC-Ame-011761	Astyanax mexicanus	50.84	2.00e-160	559.00
IUUC-Bgr-012265	Blumeria graminis	37.45	3.00e-94	339.00
IUUC-Bta-013070	Bos taurus	51.21	3.00e-160	558.00
IUUC-Bci-013890	Botrytis cinerea	36.13	1.00e-94	340.00
IUUC-Bdi-014046	Brachypodium distachyon	36.76	5.00e-96	345.00
IUUC-Bol-015942	Brassica oleracea	38.90	4.00e-99	355.00
IUUC-Bra-016849	Brassica rapa	38.90	7.00e-99	354.00
IUUC-Cja-019046	Callithrix jacchus	51.21	5.00e-160	558.00
IUUC-Cfa-020521	Canis familiaris	51.21	5.00e-160	558.00
IUUC-Cpo-021639	Cavia porcellus	51.21	7.00e-160	557.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	35.78	2.00e-86	311.00
IUUC-Csa-023231	Chlorocebus sabaeus	51.21	3.00e-160	558.00
IUUC-Cho-024380	Choloepus hoffmanni	51.40	5.00e-127	448.00
IUUC-Csv-026121	Ciona savignyi	83.67	0.00e+00	913.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	38.36	3.00e-104	372.00
IUUC-Cne-026857	Cryptococcus neoformans	35.59	4.00e-83	302.00
IUUC-Cme-027226	Cyanidioschyzon merolae	34.73	3.00e-72	266.00
IUUC-Dre-028174	Danio rerio	50.47	2.00e-159	556.00
IUUC-Dor-030939	Dipodomys ordii	45.81	2.00e-133	469.00
IUUC-Dse-031444	Dothistroma septosporum	35.96	1.00e-94	340.00
IUUC-Dme-032162	Drosophila melanogaster	51.22	2.00e-91	330.00
IUUC-Ete-032345	Echinops telfairi	43.39	1.00e-122	434.00
IUUC-Eca-033229	Equus caballus	51.21	5.00e-160	558.00
IUUC-Eeu-035205	Erinaceus europaeus	50.65	2.00e-156	545.00
IUUC-Fca-036444	Felis catus	51.21	3.00e-160	558.00
IUUC-Fal-037131	Ficedula albicollis	51.40	2.00e-161	562.00
IUUC-Fox-038035	Fusarium oxysporum	38.06	4.00e-104	370.00
IUUC-Fso-038320	Fusarium solani	37.85	3.00e-103	369.00
IUUC-Gmo-039497	Gadus morhua	51.03	2.00e-158	552.00
IUUC-Ggr-040057	Gaeumannomyces graminis	37.78	6.00e-101	362.00
IUUC-Gga-041021	Gallus gallus	51.21	6.00e-161	561.00
IUUC-Gac-042474	Gasterosteus aculeatus	50.65	2.00e-159	556.00
IUUC-Gma-043060	Glycine max	37.23	9.00e-97	347.00
IUUC-Ggo-044855	Gorilla gorilla	51.21	4.00e-160	558.00
IUUC-Hsa-046147	Homo sapiens	51.21	5.00e-160	558.00
IUUC-Hvu-047811	Hordeum vulgare	36.89	1.00e-98	353.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	51.02	2.00e-159	555.00
IUUC-Kpa-049098	Komagataella pastoris	34.08	5.00e-79	288.00
IUUC-Lch-049818	Latimeria chalumnae	50.37	2.00e-152	533.00
IUUC-Lpe-051017	Leersia perrieri	37.11	2.00e-95	343.00
IUUC-Loc-051777	Lepisosteus oculatus	51.40	4.00e-163	568.00
IUUC-Lma-052990	Leptosphaeria maculans	36.38	2.00e-100	359.00
IUUC-Laf-053727	Loxodonta africana	51.40	4.00e-160	558.00
IUUC-Mcc-055799	Macaca mulatta	51.21	4.00e-160	558.00
IUUC-Meu-056065	Macropus eugenii	48.31	3.00e-132	465.00
IUUC-Mor-057054	Magnaporthe oryzae	37.94	8.00e-103	368.00
IUUC-Mpo-057417	Magnaporthe poae	37.76	2.00e-101	363.00
IUUC-Mtr-057849	Medicago truncatula	37.04	9.00e-98	351.00
IUUC-Mla-058870	Melampsora laricipopulina	35.85	6.00e-94	338.00
IUUC-Mga-059580	Meleagris gallopavo	45.51	6.00e-75	275.00
IUUC-Mvi-060507	Microbotryum violaceum	34.64	1.00e-94	341.00
IUUC-Mmr-060816	Microcebus murinus	51.02	2.00e-158	553.00
IUUC-Mdo-062866	Monodelphis domestica	48.63	4.00e-133	468.00
IUUC-Mmu-063906	Mus musculus	51.02	5.00e-159	555.00
IUUC-Mac-064675	Musa acuminata	36.08	6.00e-95	340.00
IUUC-Mpu-066199	Mustela putorius furo	51.21	3.00e-160	559.00
IUUC-Mlu-067110	Myotis lucifugus	51.21	2.00e-158	552.00
IUUC-Nfi-068482	Neosartorya fischeri	37.62	3.00e-100	359.00
IUUC-Ncr-068906	Neurospora crassa	37.41	7.00e-101	361.00
IUUC-Nle-069410	Nomascus leucogenys	51.21	4.00e-160	558.00
IUUC-Opr-070401	Ochotona princeps	46.24	4.00e-69	256.00
IUUC-Ont-072100	Oreochromis niloticus	50.09	2.00e-157	550.00
IUUC-Oan-073121	Ornithorhynchus anatinus	51.21	1.00e-159	556.00
IUUC-Ocu-074623	Oryctolagus cuniculus	51.02	5.00e-160	558.00
IUUC-Oba-075380	Oryza barthii	36.72	1.00e-95	343.00
IUUC-Obr-076915	Oryza brachyantha	37.66	3.00e-97	349.00
IUUC-Ogl-077055	Oryza glaberrima	37.29	4.00e-96	345.00
IUUC-Ogu-078892	Oryza glumaepatula	36.72	2.00e-95	343.00
IUUC-Oin-079256	Oryza indica	36.89	4.00e-94	338.00
IUUC-Olo-080343	Oryza longistaminata	37.00	2.00e-94	340.00
IUUC-Ome-081422	Oryza meridionalis	37.00	3.00e-94	339.00
IUUC-Oni-083047	Oryza nivara	36.72	7.00e-97	347.00
IUUC-Opu-083641	Oryza punctata	36.53	2.00e-93	336.00
IUUC-Oru-084439	Oryza rufipogon	36.72	1.00e-95	343.00
IUUC-Osa-085972	Oryza sativa	37.29	4.00e-96	344.00
IUUC-Ola-087173	Oryzias latipes	49.91	6.00e-158	551.00
IUUC-Olu-087871	Ostreococcus lucimarinus	33.70	4.00e-83	300.00
IUUC-Oga-087908	Otolemur garnettii	51.21	6.00e-160	557.00
IUUC-Oar-090277	Ovis aries	51.21	2.00e-160	559.00
IUUC-Ptr-091543	Pan troglodytes	51.21	6.00e-160	557.00
IUUC-Pan-092243	Papio anubis	51.21	3.00e-160	558.00
IUUC-Psi-093150	Pelodiscus sinensis	51.02	2.00e-160	559.00
IUUC-Pno-094891	Phaeosphaeria nodorum	37.22	2.00e-101	363.00
IUUC-Ppa-095264	Physcomitrella patens	33.76	6.00e-93	334.00
IUUC-Pfo-096267	Poecilia formosa	50.28	1.00e-158	553.00
IUUC-Pab-098072	Pongo abelii	51.21	3.00e-160	558.00
IUUC-Pop-099190	Populus trichocarpa	37.80	4.00e-100	358.00
IUUC-Pca-100311	Procavia capensis	51.40	4.00e-160	558.00
IUUC-Ppe-101284	Prunus persica	38.05	2.00e-96	347.00
IUUC-Pva-102215	Pteropus vampyrus	46.55	2.00e-136	480.00
IUUC-Pgr-103694	Puccinia graminis	34.91	2.00e-91	330.00
IUUC-Ptt-103916	Puccinia triticina	34.02	8.00e-85	308.00
IUUC-Pte-104346	Pyrenophora teres	37.85	2.00e-102	366.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	38.22	4.00e-103	369.00
IUUC-Rno-105315	Rattus norvegicus	51.02	2.00e-159	556.00
IUUC-Sce-106273	Saccharomyces cerevisiae	32.65	1.00e-70	260.00
IUUC-Sha-106835	Sarcophilus harrisii	50.84	2.00e-158	553.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	35.97	4.00e-91	328.00
IUUC-Spo-108081	Schizosaccharomyces pombe	36.86	9.00e-90	324.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	36.45	4.00e-97	348.00
IUUC-Smo-109590	Selaginella moellendorffii	37.82	2.00e-100	360.00
IUUC-Sit-110717	Setaria italica	37.98	1.00e-96	347.00
IUUC-Sly-111557	Solanum lycopersicum	37.98	2.00e-100	360.00
IUUC-Stu-112896	Solanum tuberosum	37.43	2.00e-90	325.00
IUUC-Sar-113224	Sorex araneus	51.26	2.00e-116	413.00
IUUC-Sbi-114313	Sorghum bicolor	38.03	4.00e-98	352.00
IUUC-Sre-114993	Sporisorium reilianum	35.12	2.00e-85	310.00
IUUC-Ssc-115535	Sus scrofa	47.49	8.00e-135	474.00
IUUC-Tru-118669	Takifugu rubripes	49.72	1.00e-156	546.00
IUUC-Tsy-119373	Tarsius syrichta	44.35	2.00e-112	400.00
IUUC-Tni-120049	Tetraodon nigroviridis	43.38	2.00e-119	421.00
IUUC-Tca-121779	Theobroma cacao	36.59	3.00e-95	342.00
IUUC-Tre-122195	Trichoderma reesei	37.41	4.00e-98	352.00
IUUC-Tvi-122650	Trichoderma virens	36.81	1.00e-97	350.00
IUUC-Tae-123099	Triticum aestivum	37.98	1.00e-97	350.00
IUUC-Tur-126295	Triticum urartu	36.95	2.00e-96	346.00
IUUC-Tme-126964	Tuber melanosporum	36.23	8.00e-98	351.00
IUUC-Tbe-128149	Tupaia belangeri	48.40	1.00e-103	370.00
IUUC-Ttr-128165	Tursiops truncatus	51.21	3.00e-160	558.00
IUUC-Uma-129365	Ustilago maydis	34.72	2.00e-81	296.00
IUUC-Vda-129725	Verticillium dahliae	37.22	5.00e-102	365.00
IUUC-Vpa-130678	Vicugna pacos	51.21	3.00e-160	558.00
IUUC-Vvi-131147	Vitis vinifera	37.48	1.00e-99	357.00
IUUC-Xtr-132636	Xenopus tropicalis	51.39	3.00e-159	555.00
IUUC-Xma-133458	Xiphophorus maculatus	50.28	1.00e-158	553.00
IUUC-Yli-134481	Yarrowia lipolytica	33.90	2.00e-85	310.00
IUUC-Zma-135782	Zea mays	37.06	4.00e-96	345.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence