iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059543

UUCD1 version

UUC-MeG-00861

Ensembl Protein ID

ENSMGAP00000005931.1

UniProt Accession

G1N2P8; G1N2P8_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000005958.1	ENSMGAT00000006676.1	ENSMGAP00000005931.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.80e-71	239.7	5	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p++ + l e + +  +e+n++++++ l+ +l +l+++l     +++ + + + ll++l+ +  ++s++
   Q: 5    GLLNLGNTCFMNSLLQGLSSCPSFIRWLEEFTAQYKAEQNQPSEQQYLSLTLLHLLRALScqeVTEDDVLDASCLLEVLRIYRWQISTF 93
           9*****************************33333444556789999************888889999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E++++l ++le+e    ++ +++++++ ++ e++ e          + + ++++n+   ++ F+g+l+s+++c++c+++s +r
   Q: 94   EEQDAHELFHVLTSSLEDER--DRQPRVTHLFDVHSLEQQPEitqkqiscrtRGSLPPMSNHWKSQHPFHGRLTSNMVCKHCEHQSpVR 180
           *******************9..6688888888888777777777777777777788888999*************************** PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p     ++ +l++cL++f + e++++   + c++c+               +k++ +k+lkl klP++L++hL+R s+
   Q: 181  YDTFDSLSLSIPAAMWGHPMTLDHCLHHFISSESVKD---VVCDNCTkiqaegtlngqsienQKTTFVKQLKLGKLPQCLCIHLQRLSW 266
           ***********************************97...9******7777777777777777777*********************** PP
   S: 240  seeqksrekinkkvefpleLdls..pfcts.....peekqke............................................... 274
           s++ + + k +++v+f++ L ++  ++ +      +     +                                               
   Q: 267  SNQ-GTPLKRHEHVQFNEFLIMDiyKYHIPvhkstQ-----Ndlnqksseetkpgtrdgisvkpsdaeqtrgtksllmngacsssllms 349
           996.8889*********8755552266665444440.....244456666777888888888888888888999999999999999999 PP
   S: 275  ...............kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
                           + Y+L+avvvH+G ++sGH+v+y ++          +++Wl ++D++V++ + +evl+   s+aY+lfY+r
   Q: 350  sgtfpltafpecsppVYLYRLMAVVVHHGDMHSGHFVTYRRSppssksplsVSNQWLWISDDTVRKASLQEVLS---SSAYLLFYER 433
           9999999999999999**************************8887777776889*******************...********98 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

GLVPGLLNLG NTCFMNSLLQ GLSSCPSFIR WLEEFTAQYK AEQNQPSEQQ YLSLTLLHLL 60
RALSCQEVTE DDVLDASCLL EVLRIYRWQI STFEEQDAHE LFHVLTSSLE DERDRQPRVT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTGGTGC CTGGCCTGCT GAACCTCGGA AACACCTGTT TCATGAACTC CCTGCTGCAA 60
GGCCTGTCTT CGTGCCCCTC GTTCATCAGG TGGCTGGAGG AGTTCACAGC ACAGTACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	25.61	4.00e-15	75.50
IUUC-Aml-001733	Ailuropoda melanoleuca	75.22	0.00e+00	642.00
IUUC-Atr-002510	Amborella trichopoda	25.38	1.00e-21	97.80
IUUC-Apl-003645	Anas platyrhynchos	93.41	6.00e-147	512.00
IUUC-Aca-004583	Anolis carolinensis	70.15	5.00e-22	94.70
IUUC-Aly-005754	Arabidopsis lyrata	25.37	4.00e-25	108.00
IUUC-Ath-007622	Arabidopsis thaliana	28.29	3.00e-26	112.00
IUUC-Ame-010896	Astyanax mexicanus	62.16	4.00e-143	500.00
IUUC-Bta-012321	Bos taurus	74.51	0.00e+00	635.00
IUUC-Bci-013590	Botrytis cinerea	23.55	2.00e-12	67.40
IUUC-Bdi-014795	Brachypodium distachyon	25.33	9.00e-17	80.90
IUUC-Bol-015637	Brassica oleracea	26.95	2.00e-23	103.00
IUUC-Bra-016801	Brassica rapa	26.12	3.00e-23	102.00
IUUC-Cel-018308	Caenorhabditis elegans	29.81	7.00e-43	167.00
IUUC-Cja-018826	Callithrix jacchus	76.04	0.00e+00	667.00
IUUC-Cfa-021206	Canis familiaris	76.64	0.00e+00	650.00
IUUC-Cpo-021343	Cavia porcellus	76.60	0.00e+00	649.00
IUUC-Csa-023419	Chlorocebus sabaeus	76.16	0.00e+00	669.00
IUUC-Cho-024475	Choloepus hoffmanni	71.17	1.00e-100	359.00
IUUC-Cne-027061	Cryptococcus neoformans	28.75	2.00e-12	67.40
IUUC-Dre-027563	Danio rerio	59.13	3.00e-142	497.00
IUUC-Dno-029929	Dasypus novemcinctus	76.60	0.00e+00	662.00
IUUC-Dor-030166	Dipodomys ordii	64.46	9.00e-150	523.00
IUUC-Dme-031627	Drosophila melanogaster	36.24	4.00e-39	155.00
IUUC-Ete-032634	Echinops telfairi	69.69	5.00e-166	577.00
IUUC-Eca-033968	Equus caballus	75.94	0.00e+00	643.00
IUUC-Eeu-035279	Erinaceus europaeus	68.99	2.00e-43	169.00
IUUC-Fca-036525	Felis catus	76.38	0.00e+00	655.00
IUUC-Fal-036606	Ficedula albicollis	87.05	0.00e+00	631.00
IUUC-Gmo-038726	Gadus morhua	54.99	4.00e-134	471.00
IUUC-Gga-040718	Gallus gallus	97.51	0.00e+00	703.00
IUUC-Gac-042645	Gasterosteus aculeatus	58.28	5.00e-140	490.00
IUUC-Gma-042890	Glycine max	24.24	2.00e-22	100.00
IUUC-Ggo-045021	Gorilla gorilla	76.60	0.00e+00	671.00
IUUC-Hsa-045832	Homo sapiens	76.60	0.00e+00	671.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	75.94	0.00e+00	647.00
IUUC-Kpa-049268	Komagataella pastoris	21.53	6.00e-14	72.00
IUUC-Lch-050662	Latimeria chalumnae	71.20	3.00e-166	577.00
IUUC-Lpe-051078	Leersia perrieri	27.47	9.00e-29	121.00
IUUC-Loc-052611	Lepisosteus oculatus	67.63	3.00e-167	581.00
IUUC-Lma-053048	Leptosphaeria maculans	19.92	1.00e-11	65.10
IUUC-Laf-053752	Loxodonta africana	74.95	0.00e+00	634.00
IUUC-Mcc-054892	Macaca mulatta	76.60	0.00e+00	672.00
IUUC-Meu-056673	Macropus eugenii	70.79	3.00e-146	510.00
IUUC-Mor-057143	Magnaporthe oryzae	20.96	3.00e-10	60.10
IUUC-Mtr-057976	Medicago truncatula	26.91	3.00e-31	129.00
IUUC-Mla-058970	Melampsora laricipopulina	24.22	1.00e-20	94.40
IUUC-Mmr-061534	Microcebus murinus	75.82	0.00e+00	646.00
IUUC-Mdo-062140	Monodelphis domestica	64.24	8.00e-144	503.00
IUUC-Mmu-063673	Mus musculus	73.07	0.00e+00	626.00
IUUC-Mpu-066328	Mustela putorius furo	76.26	0.00e+00	650.00
IUUC-Mlu-067938	Myotis lucifugus	76.16	0.00e+00	649.00
IUUC-Nle-069426	Nomascus leucogenys	76.24	0.00e+00	646.00
IUUC-Opr-070796	Ochotona princeps	65.78	4.00e-85	308.00
IUUC-Ont-072248	Oreochromis niloticus	62.90	4.00e-145	507.00
IUUC-Oan-072916	Ornithorhynchus anatinus	75.06	0.00e+00	662.00
IUUC-Ocu-074459	Oryctolagus cuniculus	71.43	3.00e-153	533.00
IUUC-Oba-075765	Oryza barthii	27.58	5.00e-27	115.00
IUUC-Obr-076005	Oryza brachyantha	27.60	3.00e-26	112.00
IUUC-Ogl-077916	Oryza glaberrima	27.80	1.00e-29	124.00
IUUC-Ogu-078263	Oryza glumaepatula	27.98	7.00e-28	118.00
IUUC-Oin-080096	Oryza indica	28.01	5.00e-21	95.10
IUUC-Ome-081928	Oryza meridionalis	26.79	4.00e-27	115.00
IUUC-Oni-082424	Oryza nivara	27.98	7.00e-28	118.00
IUUC-Oru-085117	Oryza rufipogon	27.98	7.00e-28	118.00
IUUC-Ola-087429	Oryzias latipes	56.57	3.00e-135	474.00
IUUC-Oga-087981	Otolemur garnettii	76.16	0.00e+00	641.00
IUUC-Oar-089927	Ovis aries	74.95	0.00e+00	639.00
IUUC-Ptr-090878	Pan troglodytes	76.60	0.00e+00	671.00
IUUC-Pan-092698	Papio anubis	76.60	0.00e+00	672.00
IUUC-Psi-093451	Pelodiscus sinensis	83.44	0.00e+00	722.00
IUUC-Ppa-096015	Physcomitrella patens	21.95	5.00e-13	69.30
IUUC-Pfo-096096	Poecilia formosa	60.64	6.00e-139	486.00
IUUC-Pab-098676	Pongo abelii	75.33	0.00e+00	650.00
IUUC-Pca-100418	Procavia capensis	84.89	2.00e-107	382.00
IUUC-Ppe-101898	Prunus persica	25.35	3.00e-25	109.00
IUUC-Pva-103018	Pteropus vampyrus	73.36	0.00e+00	627.00
IUUC-Pgr-103686	Puccinia graminis	22.59	5.00e-13	69.30
IUUC-Pte-104330	Pyrenophora teres	21.65	2.00e-12	67.00
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.07	4.00e-13	69.70
IUUC-Rno-105708	Rattus norvegicus	73.29	0.00e+00	627.00
IUUC-Sha-106971	Sarcophilus harrisii	75.82	0.00e+00	659.00
IUUC-Ssl-108648	Sclerotinia sclerotiorum	21.80	3.00e-12	67.00
IUUC-Smo-109191	Selaginella moellendorffii	23.41	1.00e-13	70.50
IUUC-Sit-110442	Setaria italica	26.46	4.00e-25	108.00
IUUC-Sly-110928	Solanum lycopersicum	24.22	5.00e-17	82.00
IUUC-Stu-112223	Solanum tuberosum	24.43	4.00e-16	79.00
IUUC-Ssc-116397	Sus scrofa	75.72	0.00e+00	644.00
IUUC-Tgu-117446	Taeniopygia guttata	78.60	0.00e+00	679.00
IUUC-Tru-118268	Takifugu rubripes	58.11	5.00e-130	457.00
IUUC-Tsy-119484	Tarsius syrichta	70.94	9.00e-32	130.00
IUUC-Tni-119735	Tetraodon nigroviridis	55.33	3.00e-118	418.00
IUUC-Tca-121660	Theobroma cacao	26.31	9.00e-27	114.00
IUUC-Tae-125203	Triticum aestivum	28.51	2.00e-27	116.00
IUUC-Tur-126458	Triticum urartu	28.48	4.00e-17	82.40
IUUC-Tbe-127740	Tupaia belangeri	68.65	5.00e-164	570.00
IUUC-Ttr-129273	Tursiops truncatus	73.74	6.00e-180	623.00
IUUC-Vda-129789	Verticillium dahliae	21.74	2.00e-08	53.90
IUUC-Vvi-131177	Vitis vinifera	25.98	4.00e-29	122.00
IUUC-Xtr-132374	Xenopus tropicalis	68.41	2.00e-161	561.00
IUUC-Xma-133267	Xiphophorus maculatus	59.40	3.00e-142	498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence