iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098435

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01068137

Gene Name

ATXN3L

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000020129.1	ENSPPYT00000023474.1	ENSPPYP00000022516.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/Josephin	3.30e-74	248.6	1	180
UBD/Alpha-Helix/UIM	9.40e-06	25.2	243	257

Active Site

Position(s)	Description	Evidence
14	N/A	{ECO:0000256\|PROSITE-ProRule:PRU00331}
119		{ECO:0000256\|PROSITE-ProRule:PRU00331}
134		{ECO:0000256\|PROSITE-ProRule:PRU00331}

Domain Profile

DUB/Josephin

   S: 11   pesiyhekqrrelCalhalnnvlqdelfsreeldeiakrldeeerl.................qPskslldtGnydvnvisaalkvlGl 82
           +++i+hekq+++lCa+h+lnn+lq+e+fs++el++ia++ldeeer+                 qPs++++dtG+++++vis+alk++Gl
   Q: 1    MDFIFHEKQEGFLCAQHCLNNLLQGEYFSPVELASIAHQLDEEERMrmaeggvtseeylaflqQPSENMDDTGFFSIQVISNALKFWGL 89
           799************************************************************************************** PP
   S: 83   eavwfdkrrelqklaldnv..lgfilnlpsslslgllklplkkqhWvtvrkvgkayynldsklkaPeligdetelrkflakllqqkyse 169
           e+++f++ +e+qkl++d++  ++fi+n+              kqhW+t+rk+gk+++nl+s+l++Pel++d t+l++fla+l+qq+ys 
   Q: 90   EIIHFNN-PEYQKLGIDPIneRSFICNY--------------KQHWFTIRKFGKHWFNLNSLLAGPELVSD-TCLANFLARLQQQAYS- 161
           *******.********************..............*****************************.****************. PP
   S: 170  lllvvkeevedkesdqrldv 189
            ++vvk++++d+e+dq+l++
   Q: 162  -VFVVKGDLPDCEADQLLQI 180
           .****************996 PP

UBD/Alpha-Helix/UIM

   S: 2    EdeeLqlAlalSlqE 16
           Ede+L++A++lS+q 
   Q: 243  EDEDLRRAIELSMQG 257
           9************97 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDFIFHEKQE GFLCAQHCLN NLLQGEYFSP VELASIAHQL DEEERMRMAE GGVTSEEYLA 60
FLQQPSENMD DTGFFSIQVI SNALKFWGLE IIHFNNPEYQ KLGIDPINER SFICNYKQHW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTTCA TCTTTCATGA GAAACAGGAA GGTTTCTTGT GTGCTCAGCA CTGTCTGAAC 60
AATCTATTGC AAGGAGAATA TTTTAGCCCT GTGGAATTAG CCTCAATTGC ACATCAGCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR009068--S15_NS1_RNA-bd
IPR003903--UIM_dom

PROSITE

PS50957--JOSEPHIN
PS50330--UIM

Pfam

PF02099--Josephin
PF02809--UIM

SMART

SM01246--Josephin
SM00726--UIM

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Atr-002735	Amborella trichopoda	52.08	1.00e-06	44.30
IUUC-Aly-005625	Arabidopsis lyrata	43.45	3.00e-37	148.00
IUUC-Ath-007088	Arabidopsis thaliana	43.20	2.00e-37	148.00
IUUC-Ame-010715	Astyanax mexicanus	63.77	4.00e-96	344.00
IUUC-Bdi-015000	Brachypodium distachyon	40.00	2.00e-31	129.00
IUUC-Bol-015894	Brassica oleracea	43.45	9.00e-38	151.00
IUUC-Bra-018020	Brassica rapa	43.71	6.00e-38	151.00
IUUC-Cel-018121	Caenorhabditis elegans	32.76	5.00e-40	157.00
IUUC-Cja-019310	Callithrix jacchus	69.86	9.00e-136	476.00
IUUC-Csa-023257	Chlorocebus sabaeus	90.14	0.00e+00	642.00
IUUC-Cme-027158	Cyanidioschyzon merolae	31.87	6.00e-16	77.00
IUUC-Gmo-039718	Gadus morhua	62.50	1.00e-90	326.00
IUUC-Gac-041671	Gasterosteus aculeatus	63.04	1.00e-85	309.00
IUUC-Gma-042801	Glycine max	39.29	3.00e-33	135.00
IUUC-Hsa-047013	Homo sapiens	96.06	0.00e+00	685.00
IUUC-Hvu-047492	Hordeum vulgare	41.18	8.00e-31	127.00
IUUC-Lpe-050819	Leersia perrieri	33.71	2.00e-32	132.00
IUUC-Loc-051816	Lepisosteus oculatus	59.93	3.00e-103	368.00
IUUC-Mcc-054793	Macaca mulatta	85.00	4.00e-161	560.00
IUUC-Mtr-058233	Medicago truncatula	33.58	2.00e-34	139.00
IUUC-Mla-059013	Melampsora laricipopulina	33.83	8.00e-28	117.00
IUUC-Nle-069430	Nomascus leucogenys	92.68	7.00e-179	619.00
IUUC-Oba-075288	Oryza barthii	33.33	4.00e-34	138.00
IUUC-Obr-076050	Oryza brachyantha	41.28	1.00e-29	124.00
IUUC-Ogl-077174	Oryza glaberrima	33.33	4.00e-34	138.00
IUUC-Ogu-078006	Oryza glumaepatula	33.33	4.00e-34	138.00
IUUC-Oin-079278	Oryza indica	32.12	1.00e-31	130.00
IUUC-Olo-080941	Oryza longistaminata	33.33	4.00e-34	138.00
IUUC-Ome-081172	Oryza meridionalis	32.95	3.00e-33	135.00
IUUC-Oni-082239	Oryza nivara	33.33	4.00e-34	138.00
IUUC-Opu-083939	Oryza punctata	33.58	3.00e-34	138.00
IUUC-Oru-084393	Oryza rufipogon	33.33	4.00e-34	138.00
IUUC-Osa-086080	Oryza sativa	33.33	4.00e-34	138.00
IUUC-Ptr-090897	Pan troglodytes	91.27	2.00e-178	617.00
IUUC-Pan-092742	Papio anubis	90.70	0.00e+00	646.00
IUUC-Psi-093313	Pelodiscus sinensis	72.62	2.00e-106	378.00
IUUC-Pma-094374	Petromyzon marinus	50.19	3.00e-71	261.00
IUUC-Ppa-095601	Physcomitrella patens	40.74	1.00e-41	163.00
IUUC-Pfo-097327	Poecilia formosa	59.03	3.00e-91	328.00
IUUC-Pca-101022	Procavia capensis	86.61	2.00e-57	215.00
IUUC-Ppe-101545	Prunus persica	41.42	4.00e-35	141.00
IUUC-Pyt-104473	Pyrenophora triticirepentis	47.06	1.20e-01	31.60
IUUC-Sit-110477	Setaria italica	41.86	3.00e-33	135.00
IUUC-Sbi-114751	Sorghum bicolor	40.80	3.00e-31	128.00
IUUC-Tru-118059	Takifugu rubripes	65.64	2.00e-88	318.00
IUUC-Tsy-119448	Tarsius syrichta	67.33	6.00e-73	267.00
IUUC-Tni-120681	Tetraodon nigroviridis	82.81	1.00e-54	204.00
IUUC-Tca-121442	Theobroma cacao	34.07	9.00e-37	146.00
IUUC-Tae-123969	Triticum aestivum	30.45	1.00e-28	120.00
IUUC-Uma-129359	Ustilago maydis	39.68	8.00e-35	141.00
IUUC-Vda-129976	Verticillium dahliae	45.71	5.80e-01	30.40
IUUC-Vvi-131227	Vitis vinifera	42.86	5.00e-34	137.00
IUUC-Xma-133144	Xiphophorus maculatus	59.52	4.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence