iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cre-022673

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-protein ligase

Genbank Nucleotide ID

DS496141

Gene Name

UBC8; CHLREDRAFT_34875

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CHLREDRAFT_34875	EDP00167	EDP00167

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-75	254.6	906	1258

Active Site

Position(s)	Description	Evidence
1226	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfy 97
            lk+rl+v+f +     E+gld gG+++e l+ ++++  ++++glf+ ++++ +  +p+ +++   p  l l ef+G + gkal++g ll++p++++f 
   Q: 906  GLKARLQVTFINeagmtEAGLDFGGLQKELLERVVSAGLDANYGLFTSTPDGLAYPNPAAERI---PGGLALLEFMGLMFGKALYEGILLPVPFAHFFV 1001
           5899********8888888***************************99999999877777775...79******************************* PP
   S: 98   klllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreG 196
            +l g++  ++dl+++dpel+k+l  +k++ e d+++  l+l+fs++++ +g+  ++eL+pg  ++pVtn+ +  Y++l+++++l+ +     +af +G
   Q: 1002 ARLQGRQPLFDDLATLDPELHKNLLMVKRY-EGDVTD--LCLSFSAETDYFGTPVHHELLPGRGDEPVTNDSRLLYCHLLADWHLNGKLGPPAAAFARG 1097
           ******************************.667777..68899999999************************************************* PP
   S: 197  fneviplellslFteeelellicGe.ee.........idvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkpr 285
           + ++ip+ +l+lF+++e+++l++G  ++         +dv d+++ +ky ggy +ds +++ Fw+v+ e++  +++a+L+FvT++sr PlgGf++l+p 
   Q: 1098 LFNLIPQASLRLFNPREFNQLLSGAaADgpggagvaaLDVADMRRYAKYSGGYRHDSTTVKLFWRVVAELTPAQQAALLRFVTSCSRPPLGGFRYLQPP 1196
           **********************9874323444444449***********************************************************99 PP
   S: 286  lfvirk...........dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           l+  +             ++ drlPs++TC+n+LkLP+Y    +lk kLly i++++gFels
   Q: 1197 LTLHKVdcdaglfaaigGRDVDRLPSASTCYNMLKLPNYRRAATLKAKLLYSITSGAGFELS 1258
           66555599999*999955555**************************************985 PP

Organism

Chlamydomonas reinhardtii

Protein Sequence
(Fasta)

MVVGSRGGLR WLGLRAGDEL LEAVRAERAA RSGAKAKAKS AVVIQRAWRG HVARRQLRAA 60
LVSEWATSFG PLVTAPTAQI AAADVAGKLL PPFLFLLKPP PTPAAGSSAV GGPGKNAGSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGTGG GCTCACGTGG TGGGCTTCGG TGGCTTGGAC TCAGGGCTGG GTGGGTGTGC 60
GCAGCCGTGC CTGTTGCTGT CAGGGTTGTG TCAATGTGGC ACCCGTGCCT TGTCGCGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

cre:CHLREDRAFT_34875

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	46.92	8.00e-108	383.00
IUUC-Atr-003017	Amborella trichopoda	46.65	2.00e-110	392.00
IUUC-Aly-005794	Arabidopsis lyrata	47.88	4.00e-117	414.00
IUUC-Ath-007269	Arabidopsis thaliana	48.35	4.00e-121	427.00
IUUC-Bdi-014502	Brachypodium distachyon	47.87	7.00e-114	403.00
IUUC-Bol-015093	Brassica oleracea	48.11	2.00e-119	421.00
IUUC-Bra-016722	Brassica rapa	48.11	5.00e-120	424.00
IUUC-Cin-025750	Ciona intestinalis	37.53	1.00e-73	270.00
IUUC-Csv-026016	Ciona savignyi	36.24	3.00e-76	278.00
IUUC-Cne-026841	Cryptococcus neoformans	38.24	1.00e-72	266.00
IUUC-Dme-031602	Drosophila melanogaster	36.83	5.00e-78	284.00
IUUC-Ete-033041	Echinops telfairi	35.74	1.00e-49	190.00
IUUC-Fso-038088	Fusarium solani	34.86	3.00e-69	255.00
IUUC-Gac-042088	Gasterosteus aculeatus	35.21	4.00e-77	281.00
IUUC-Gma-042728	Glycine max	47.84	2.00e-112	399.00
IUUC-Hvu-047102	Hordeum vulgare	46.45	5.00e-107	380.00
IUUC-Lch-050664	Latimeria chalumnae	36.14	4.00e-77	281.00
IUUC-Lpe-050755	Leersia perrieri	47.14	2.00e-108	385.00
IUUC-Laf-053902	Loxodonta africana	36.57	6.00e-79	287.00
IUUC-Mtr-057671	Medicago truncatula	47.14	1.00e-112	399.00
IUUC-Mvi-060445	Microbotryum violaceum	37.94	9.00e-75	273.00
IUUC-Mac-064989	Musa acuminata	47.88	2.00e-110	392.00
IUUC-Opr-070554	Ochotona princeps	36.34	9.00e-78	283.00
IUUC-Oba-075213	Oryza barthii	47.16	2.00e-108	385.00
IUUC-Obr-076320	Oryza brachyantha	47.87	9.00e-112	396.00
IUUC-Ogl-077093	Oryza glaberrima	47.63	3.00e-111	394.00
IUUC-Ogu-078235	Oryza glumaepatula	45.27	2.00e-97	348.00
IUUC-Oin-080058	Oryza indica	47.63	4.00e-111	394.00
IUUC-Olo-080742	Oryza longistaminata	47.63	4.00e-111	394.00
IUUC-Ome-081741	Oryza meridionalis	48.02	5.00e-104	370.00
IUUC-Oni-082616	Oryza nivara	45.27	2.00e-97	348.00
IUUC-Opu-083529	Oryza punctata	47.87	2.00e-111	395.00
IUUC-Oru-085128	Oryza rufipogon	45.27	3.00e-97	348.00
IUUC-Osa-085557	Oryza sativa	47.63	1.00e-110	392.00
IUUC-Olu-087902	Ostreococcus lucimarinus	43.61	3.00e-100	356.00
IUUC-Ppa-095544	Physcomitrella patens	46.65	2.00e-112	399.00
IUUC-Pab-098570	Pongo abelii	36.57	1.00e-78	286.00
IUUC-Ppe-101281	Prunus persica	46.23	3.00e-112	398.00
IUUC-Pva-102887	Pteropus vampyrus	36.57	1.00e-78	286.00
IUUC-Pgr-103513	Puccinia graminis	37.38	7.00e-75	274.00
IUUC-Ptt-103967	Puccinia triticina	37.14	7.00e-69	253.00
IUUC-Rno-106028	Rattus norvegicus	34.90	1.00e-65	243.00
IUUC-Sha-107331	Sarcophilus harrisii	35.67	1.00e-78	286.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	35.38	1.00e-70	259.00
IUUC-Smo-109537	Selaginella moellendorffii	45.41	4.00e-107	381.00
IUUC-Sit-109811	Setaria italica	48.58	1.00e-112	399.00
IUUC-Sly-111013	Solanum lycopersicum	46.73	2.00e-104	372.00
IUUC-Sar-113687	Sorex araneus	39.36	2.00e-48	185.00
IUUC-Sbi-114433	Sorghum bicolor	47.63	1.00e-109	389.00
IUUC-Ssc-116103	Sus scrofa	36.57	3.00e-78	285.00
IUUC-Tca-121770	Theobroma cacao	47.17	9.00e-114	403.00
IUUC-Tae-124300	Triticum aestivum	52.98	1.00e-85	307.00
IUUC-Tur-126086	Triticum urartu	46.92	1.00e-107	383.00
IUUC-Vvi-131524	Vitis vinifera	48.35	6.00e-112	397.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence