iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oga-088342

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03070137

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015177.2	ENSOGAT00000015185.2	ENSOGAP00000013594.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.20e-111	372.0	702	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d+  l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 702  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFTTTSGDE-RLYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 786
           7899********************************************8877655.569*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di +lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 787  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDSEFYKNLTSIKRY-DGDIADLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 870
           ********************777777999********************.6788887777766..6999****************** PP
   S: 166  tne.NkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFw 250
           tne N+ +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlk++t y gg++ ++++i+w+w
   Q: 871  TNEsNRISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSTPELQRLISGDnAEIDLEDLKRHTVYYGGFHGSHRVIIWLW 957
           *865*****************************************************9***************************** PP
   S: 251  evl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPe 312
           ++l ++f+ eer++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+
   Q: 958  DILaSDFTPEERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPN 1044
           ***99*************************************************************8888***************** PP
   S: 313  YsskeilkekLlyAieetkgFels 336
           Ys+k++l+ekL+yAi++++gFels
   Q: 1045 YSKKSVLREKLRYAISMNTGFELS 1068
           *********************985 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQRERE RAAVEIQAHV RSFLSRTRLR RDIRREIDEF 60
LKEDSGSSKR SALSIFKIAR KLLFLFKIKE DNERFEKLCR SILSSMDAEN EPKVWYVSLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTACCG TATCTCAAAC ATCGAGAGCG TGGTTCATTG ATAGAGCCCG TCAGGCCCGA 60
GAAGAAAGGC TCGTGCAAAG AGAGCGGGAG CGGGCAGCCG TTGAGATTCA GGCTCACGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.18	3.00e-104	373.00
IUUC-Aml-002107	Ailuropoda melanoleuca	95.98	0.00e+00	2055.00
IUUC-Atr-003017	Amborella trichopoda	37.88	3.00e-108	386.00
IUUC-Apl-003328	Anas platyrhynchos	89.73	0.00e+00	1847.00
IUUC-Aly-005794	Arabidopsis lyrata	39.04	2.00e-108	387.00
IUUC-Ath-007269	Arabidopsis thaliana	39.04	2.00e-110	394.00
IUUC-Bta-013547	Bos taurus	95.51	0.00e+00	2088.00
IUUC-Bdi-014502	Brachypodium distachyon	38.72	8.00e-108	385.00
IUUC-Bol-015093	Brassica oleracea	39.93	7.00e-112	399.00
IUUC-Bra-016722	Brassica rapa	39.93	1.00e-112	401.00
IUUC-Cel-018447	Caenorhabditis elegans	39.50	0.00e+00	684.00
IUUC-Cja-019855	Callithrix jacchus	95.70	0.00e+00	2057.00
IUUC-Cfa-020066	Canis familiaris	95.56	0.00e+00	2031.00
IUUC-Cpo-021504	Cavia porcellus	94.57	0.00e+00	2051.00
IUUC-Csa-023579	Chlorocebus sabaeus	95.79	0.00e+00	2055.00
IUUC-Cho-024430	Choloepus hoffmanni	85.06	0.00e+00	1537.00
IUUC-Cin-025750	Ciona intestinalis	47.12	0.00e+00	963.00
IUUC-Csv-026016	Ciona savignyi	47.48	0.00e+00	1008.00
IUUC-Dre-028271	Danio rerio	80.67	0.00e+00	1734.00
IUUC-Dno-029054	Dasypus novemcinctus	95.51	0.00e+00	2051.00
IUUC-Dor-030938	Dipodomys ordii	87.00	0.00e+00	1829.00
IUUC-Dme-031602	Drosophila melanogaster	47.55	0.00e+00	956.00
IUUC-Ete-033041	Echinops telfairi	75.88	0.00e+00	1335.00
IUUC-Eca-034411	Equus caballus	95.98	0.00e+00	2046.00
IUUC-Eeu-035201	Erinaceus europaeus	84.30	0.00e+00	799.00
IUUC-Fca-036594	Felis catus	94.57	0.00e+00	2029.00
IUUC-Fal-037317	Ficedula albicollis	84.50	0.00e+00	1842.00
IUUC-Gmo-039412	Gadus morhua	77.11	0.00e+00	1705.00
IUUC-Gga-040149	Gallus gallus	87.96	0.00e+00	1870.00
IUUC-Gac-042088	Gasterosteus aculeatus	79.29	0.00e+00	1780.00
IUUC-Gma-043839	Glycine max	39.36	2.00e-110	394.00
IUUC-Ggo-045279	Gorilla gorilla	95.60	0.00e+00	2049.00
IUUC-Hsa-045660	Homo sapiens	95.32	0.00e+00	2043.00
IUUC-Hvu-047102	Hordeum vulgare	39.01	1.00e-103	371.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	94.14	0.00e+00	1037.00
IUUC-Lch-050664	Latimeria chalumnae	81.90	0.00e+00	1803.00
IUUC-Lpe-050755	Leersia perrieri	36.62	2.00e-96	347.00
IUUC-Loc-052791	Lepisosteus oculatus	82.14	0.00e+00	1758.00
IUUC-Laf-053902	Loxodonta africana	95.32	0.00e+00	2048.00
IUUC-Mcc-054730	Macaca mulatta	95.70	0.00e+00	2055.00
IUUC-Meu-056527	Macropus eugenii	79.31	0.00e+00	1654.00
IUUC-Mtr-057671	Medicago truncatula	39.72	7.00e-111	395.00
IUUC-Mga-059260	Meleagris gallopavo	87.79	0.00e+00	1868.00
IUUC-Mmr-060804	Microcebus murinus	95.51	0.00e+00	2013.00
IUUC-Mdo-062575	Monodelphis domestica	83.49	0.00e+00	1758.00
IUUC-Mmu-063636	Mus musculus	91.60	0.00e+00	1911.00
IUUC-Mac-064989	Musa acuminata	39.12	2.00e-105	377.00
IUUC-Mpu-066677	Mustela putorius furo	95.63	0.00e+00	1921.00
IUUC-Mlu-067952	Myotis lucifugus	94.86	0.00e+00	1976.00
IUUC-Nle-069153	Nomascus leucogenys	95.51	0.00e+00	2045.00
IUUC-Opr-070554	Ochotona princeps	94.39	0.00e+00	1877.00
IUUC-Ont-071372	Oreochromis niloticus	80.75	0.00e+00	1766.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.21	0.00e+00	744.00
IUUC-Ocu-074183	Oryctolagus cuniculus	94.49	0.00e+00	2014.00
IUUC-Oba-075213	Oryza barthii	38.41	1.00e-104	374.00
IUUC-Obr-076320	Oryza brachyantha	39.01	2.00e-107	384.00
IUUC-Ogl-077093	Oryza glaberrima	38.58	2.00e-107	383.00
IUUC-Ogu-078947	Oryza glumaepatula	35.80	3.00e-107	383.00
IUUC-Oin-080058	Oryza indica	38.68	5.00e-107	382.00
IUUC-Olo-080742	Oryza longistaminata	38.41	6.00e-106	379.00
IUUC-Ome-081741	Oryza meridionalis	37.89	1.00e-99	358.00
IUUC-Oni-082385	Oryza nivara	35.80	2.00e-107	383.00
IUUC-Opu-083529	Oryza punctata	38.58	6.00e-107	382.00
IUUC-Oru-085128	Oryza rufipogon	36.93	1.00e-93	337.00
IUUC-Osa-085557	Oryza sativa	38.68	1.00e-106	380.00
IUUC-Ola-087337	Oryzias latipes	79.91	0.00e+00	1704.00
IUUC-Oar-090234	Ovis aries	95.18	0.00e+00	2061.00
IUUC-Ptr-091661	Pan troglodytes	95.60	0.00e+00	2049.00
IUUC-Pan-092728	Papio anubis	95.88	0.00e+00	2062.00
IUUC-Psi-093251	Pelodiscus sinensis	86.11	0.00e+00	1715.00
IUUC-Pma-094195	Petromyzon marinus	69.40	0.00e+00	1428.00
IUUC-Ppa-095544	Physcomitrella patens	37.97	7.00e-110	392.00
IUUC-Pfo-097472	Poecilia formosa	80.19	0.00e+00	1771.00
IUUC-Pab-098570	Pongo abelii	95.51	0.00e+00	2048.00
IUUC-Pca-100110	Procavia capensis	83.26	0.00e+00	1733.00
IUUC-Ppe-101281	Prunus persica	38.58	8.00e-106	378.00
IUUC-Pva-102887	Pteropus vampyrus	90.56	0.00e+00	1904.00
IUUC-Rno-106028	Rattus norvegicus	88.06	0.00e+00	1809.00
IUUC-Sha-107331	Sarcophilus harrisii	84.53	0.00e+00	1789.00
IUUC-Smo-109488	Selaginella moellendorffii	36.72	2.00e-104	373.00
IUUC-Sit-109811	Setaria italica	35.70	1.00e-109	391.00
IUUC-Sly-111013	Solanum lycopersicum	38.96	6.00e-102	365.00
IUUC-Sar-113287	Sorex araneus	85.48	0.00e+00	708.00
IUUC-Sbi-114433	Sorghum bicolor	35.61	3.00e-109	390.00
IUUC-Ssc-116103	Sus scrofa	95.98	0.00e+00	2046.00
IUUC-Tgu-117275	Taeniopygia guttata	87.77	0.00e+00	1855.00
IUUC-Tru-118681	Takifugu rubripes	79.63	0.00e+00	1788.00
IUUC-Tsy-118985	Tarsius syrichta	91.21	0.00e+00	1013.00
IUUC-Tni-120850	Tetraodon nigroviridis	90.50	0.00e+00	769.00
IUUC-Tca-121770	Theobroma cacao	38.94	1.00e-110	394.00
IUUC-Tae-125466	Triticum aestivum	36.29	4.00e-105	376.00
IUUC-Tur-126086	Triticum urartu	39.18	1.00e-103	371.00
IUUC-Tbe-127461	Tupaia belangeri	90.74	0.00e+00	1882.00
IUUC-Ttr-129269	Tursiops truncatus	95.14	0.00e+00	2027.00
IUUC-Vpa-130523	Vicugna pacos	75.40	3.00e-124	439.00
IUUC-Vvi-131524	Vitis vinifera	38.79	3.00e-108	386.00
IUUC-Xtr-132146	Xenopus tropicalis	83.60	0.00e+00	1819.00
IUUC-Xma-133526	Xiphophorus maculatus	79.91	0.00e+00	1767.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence