iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089353

Ensembl Protein ID

ENSOARP00000012858.1

UniProt Accession

W5PQY0; W5PQY0_SHEEP

Genbank Protein ID

ENSOARP00000012858

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01074873

Gene Name

LRSAM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000011992.1	ENSOART00000013045.1	ENSOARP00000012858.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.01	0.00e+00	1006.00	IUUC-Hsa-046865

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ovis aries

Protein Sequence
(Fasta)

MPLFFRKRKP SEEARKRLEY QMCLAKEAGA DDILDISKCE LSEIPFGAFA TCKVLQKKVL 60
IVHTNLLTSL LPKSCSLLSL TTIKVLDLHD NQLTALPDDI GQLTALQVLN VERNQLTCLP 120

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Nucleotide Sequence
(Fasta)

ATGCCACTCT TCTTCCGGAA GCGGAAACCC AGCGAGGAGG CTCGGAAACG CCTGGAGTAC 60
CAGATGTGTC TGGTGAGGGA AATGGGTTTC CTCCAAGTCT ATGCCCATCT CCACCTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0433--Leucine-rich repeat
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR025875--Leu-rich_rpt_4
IPR003591--Leu-rich_rpt_typical-subtyp
IPR001841--Znf_RING

PROSITE

PS51450--LRR
PS50089--ZF_RING_2

Pfam

PF12799--LRR_4
PF13855--LRR_8

SMART

SM00369--LRR_TYP

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045806--P:negative regulation of endocytosis
GO:2000786--P:positive regulation of autophagosome assembly
GO:1904417--P:positive regulation of xenophagy
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0070086--P:ubiquitin-dependent endocytosis
GO:0046755--P:viral budding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001663	Ailuropoda melanoleuca	82.18	0.00e+00	970.00
IUUC-Atr-002698	Amborella trichopoda	45.28	3.00e-09	56.20
IUUC-Apl-004029	Anas platyrhynchos	68.84	9.00e-165	573.00
IUUC-Aca-004487	Anolis carolinensis	61.29	0.00e+00	688.00
IUUC-Aly-005571	Arabidopsis lyrata	33.58	6.00e-14	73.20
IUUC-Ath-006853	Arabidopsis thaliana	33.76	7.00e-17	81.30
IUUC-Ate-010322	Aspergillus terreus	37.50	4.00e-09	57.80
IUUC-Ame-011792	Astyanax mexicanus	51.84	0.00e+00	671.00
IUUC-Bta-012937	Bos taurus	90.78	0.00e+00	1130.00
IUUC-Bdi-014104	Brachypodium distachyon	38.74	1.00e-08	54.30
IUUC-Bol-016339	Brassica oleracea	30.82	7.00e-15	74.70
IUUC-Bra-016795	Brassica rapa	30.82	1.00e-14	73.90
IUUC-Cja-019359	Callithrix jacchus	83.02	0.00e+00	941.00
IUUC-Cfa-020908	Canis familiaris	82.38	0.00e+00	984.00
IUUC-Cpo-021744	Cavia porcellus	77.05	0.00e+00	929.00
IUUC-Csa-023784	Chlorocebus sabaeus	85.42	0.00e+00	1004.00
IUUC-Cin-025241	Ciona intestinalis	35.09	5.00e-98	352.00
IUUC-Dre-027424	Danio rerio	53.14	0.00e+00	667.00
IUUC-Dno-028857	Dasypus novemcinctus	83.86	0.00e+00	967.00
IUUC-Dor-030397	Dipodomys ordii	78.53	2.00e-98	353.00
IUUC-Ete-032958	Echinops telfairi	56.66	1.00e-118	420.00
IUUC-Eca-033505	Equus caballus	85.14	0.00e+00	1020.00
IUUC-Eeu-035089	Erinaceus europaeus	74.96	0.00e+00	789.00
IUUC-Fca-036318	Felis catus	81.69	0.00e+00	988.00
IUUC-Fal-037299	Ficedula albicollis	67.63	0.00e+00	755.00
IUUC-Gmo-038494	Gadus morhua	55.88	0.00e+00	628.00
IUUC-Gga-041180	Gallus gallus	68.58	0.00e+00	833.00
IUUC-Gac-041975	Gasterosteus aculeatus	52.00	2.00e-170	592.00
IUUC-Gma-043846	Glycine max	36.90	5.00e-11	62.00
IUUC-Ggo-045293	Gorilla gorilla	80.88	0.00e+00	925.00
IUUC-Hsa-046865	Homo sapiens	85.01	0.00e+00	1000.00
IUUC-Hvu-047769	Hordeum vulgare	38.38	6.00e-13	68.60
IUUC-Itr-048290	Ictidomys tridecemlineatus	81.23	0.00e+00	966.00
IUUC-Lch-049955	Latimeria chalumnae	50.47	6.00e-164	570.00
IUUC-Loc-052396	Lepisosteus oculatus	54.58	1.00e-129	457.00
IUUC-Laf-054274	Loxodonta africana	85.79	0.00e+00	962.00
IUUC-Mcc-055328	Macaca mulatta	85.56	0.00e+00	1007.00
IUUC-Meu-056407	Macropus eugenii	74.77	4.00e-81	295.00
IUUC-Mtr-057683	Medicago truncatula	29.41	1.00e-13	70.90
IUUC-Mga-059898	Meleagris gallopavo	68.85	0.00e+00	847.00
IUUC-Mmr-061558	Microcebus murinus	82.92	0.00e+00	1001.00
IUUC-Mdo-062877	Monodelphis domestica	75.67	0.00e+00	918.00
IUUC-Mmu-063525	Mus musculus	81.67	0.00e+00	989.00
IUUC-Mac-064501	Musa acuminata	32.45	2.00e-13	69.70
IUUC-Mpu-066491	Mustela putorius furo	81.48	0.00e+00	959.00
IUUC-Mlu-068182	Myotis lucifugus	75.77	0.00e+00	888.00
IUUC-Nle-069349	Nomascus leucogenys	84.73	0.00e+00	982.00
IUUC-Opr-070326	Ochotona princeps	74.43	0.00e+00	795.00
IUUC-Ont-071685	Oreochromis niloticus	51.13	0.00e+00	661.00
IUUC-Oan-072957	Ornithorhynchus anatinus	78.28	0.00e+00	920.00
IUUC-Obr-076454	Oryza brachyantha	35.14	7.00e-15	74.70
IUUC-Ogl-077480	Oryza glaberrima	33.78	3.00e-13	69.30
IUUC-Oin-079319	Oryza indica	32.43	1.00e-12	67.80
IUUC-Olo-080705	Oryza longistaminata	43.40	5.00e-08	52.40
IUUC-Ome-081910	Oryza meridionalis	30.62	3.00e-11	63.50
IUUC-Oga-088129	Otolemur garnettii	84.30	0.00e+00	977.00
IUUC-Ptr-091511	Pan troglodytes	85.40	0.00e+00	1007.00
IUUC-Pan-092251	Papio anubis	85.28	0.00e+00	1002.00
IUUC-Psi-093778	Pelodiscus sinensis	61.16	0.00e+00	689.00
IUUC-Pma-094158	Petromyzon marinus	45.01	1.00e-121	430.00
IUUC-Ppa-095427	Physcomitrella patens	33.33	1.00e-14	74.30
IUUC-Pfo-096094	Poecilia formosa	52.03	0.00e+00	632.00
IUUC-Pab-098187	Pongo abelii	80.47	0.00e+00	912.00
IUUC-Pop-099197	Populus trichocarpa	31.25	7.00e-14	71.60
IUUC-Pca-100526	Procavia capensis	81.50	1.00e-126	447.00
IUUC-Ppe-101851	Prunus persica	38.10	3.00e-14	72.80
IUUC-Pva-102557	Pteropus vampyrus	80.36	0.00e+00	906.00
IUUC-Pgr-103622	Puccinia graminis	33.93	4.00e-12	67.80
IUUC-Pyt-104751	Pyrenophora triticirepentis	35.23	7.00e-12	66.20
IUUC-Rno-105540	Rattus norvegicus	80.05	0.00e+00	987.00
IUUC-Sha-107485	Sarcophilus harrisii	75.72	0.00e+00	899.00
IUUC-Sit-109922	Setaria italica	52.17	5.00e-12	65.10
IUUC-Sly-111052	Solanum lycopersicum	32.45	1.00e-15	77.40
IUUC-Stu-112067	Solanum tuberosum	29.59	9.00e-17	80.90
IUUC-Sar-113098	Sorex araneus	70.16	0.00e+00	750.00
IUUC-Sbi-114187	Sorghum bicolor	39.29	5.00e-10	58.50
IUUC-Ssc-116105	Sus scrofa	80.41	0.00e+00	946.00
IUUC-Tgu-116857	Taeniopygia guttata	68.63	3.00e-175	607.00
IUUC-Tru-117930	Takifugu rubripes	49.33	0.00e+00	628.00
IUUC-Tsy-119382	Tarsius syrichta	78.48	2.00e-92	332.00
IUUC-Tni-120714	Tetraodon nigroviridis	54.23	7.00e-158	550.00
IUUC-Tca-121678	Theobroma cacao	31.03	9.00e-15	74.30
IUUC-Tae-125723	Triticum aestivum	33.11	4.00e-13	68.90
IUUC-Tur-126470	Triticum urartu	50.00	1.00e-11	63.50
IUUC-Tbe-127528	Tupaia belangeri	92.59	1.00e-60	228.00
IUUC-Ttr-128282	Tursiops truncatus	87.28	0.00e+00	1014.00
IUUC-Vda-129866	Verticillium dahliae	37.14	4.00e-07	50.80
IUUC-Vpa-130740	Vicugna pacos	73.14	0.00e+00	686.00
IUUC-Vvi-131710	Vitis vinifera	52.17	2.00e-12	66.20
IUUC-Xtr-132037	Xenopus tropicalis	58.95	0.00e+00	661.00
IUUC-Xma-133788	Xiphophorus maculatus	46.19	4.00e-109	388.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence