iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ont-071783

Ensembl Protein ID

ENSONIP00000014311.1

UniProt Accession

I3JZL6; I3JZL6_ORENI

Genbank Protein ID

ENSONIP00000014311

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AERX01030171

Gene Name

fynb; fyn

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000011372.1	ENSONIT00000014322.1	ENSONIP00000014311.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.20e-15	56.2	88	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +lydyea ++d+L++kkG+  ++i  ++++++W+ + + ++g +G +P+n+v+ ++
   Q: 88   FVALYDYEARTEDDLSFKKGERFQII--NSTEGDWWDARSLTTGGSGYIPSNYVAPVD 143
           789***********************..8999**********************9987 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

IMGCVQCKDK EATKLTDDRD NSTSQGAGYR YGADPTPQHY PNFGVTAIPN YNNFHAPVGQ 60
GMTVFGGVST SSHTGTLRTR GGTGVTLFVA LYDYEARTED DLSFKKGERF QIINSTEGDW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAATGGGCT GTGTGCAATG CAAGGATAAG GAGGCAACCA AACTCACAGA TGACCGAGAC 60
AACAGCACCT CCCAGGGAGC GGGCTACCGC TATGGAGCCG ACCCCACGCC ACAGCACTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0060027--P:convergent extension involved in gastrulation
GO:0031101--P:fin regeneration
GO:0045859--P:regulation of protein kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005712	Arabidopsis lyrata	32.76	2.00e-20	95.10
IUUC-Bol-016049	Brassica oleracea	32.03	3.00e-18	87.40
IUUC-Dno-030043	Dasypus novemcinctus	77.03	0.00e+00	900.00
IUUC-Eeu-034582	Erinaceus europaeus	89.91	0.00e+00	634.00
IUUC-Lch-049825	Latimeria chalumnae	91.43	0.00e+00	1005.00
IUUC-Loc-052531	Lepisosteus oculatus	93.67	0.00e+00	1061.00
IUUC-Mga-060067	Meleagris gallopavo	92.02	0.00e+00	1019.00
IUUC-Psi-093602	Pelodiscus sinensis	92.36	0.00e+00	1024.00
IUUC-Pfo-097519	Poecilia formosa	96.69	0.00e+00	1096.00
IUUC-Sar-113016	Sorex araneus	81.19	0.00e+00	879.00
IUUC-Tru-117596	Takifugu rubripes	93.36	0.00e+00	1061.00
IUUC-Xtr-132293	Xenopus tropicalis	86.22	0.00e+00	948.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence