iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pab-097881

Ensembl Protein ID

ENSPPYP00000003643.2

UniProt Accession

H2ND49; H2ND49_PONAB

Genbank Protein ID

ENSPPYP00000003643

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01138852

Gene Name

UBXN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000003153.2	ENSPPYT00000003772.2	ENSPPYP00000003643.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	5.10e-09	36.1	4	42
ULD/UDP/UFD/UBX	3.90e-20	72.3	209	290

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 4    edkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
             +le l+eMGF+r +a +aL+ + n  +eaA+++L+++
   Q: 4    LTALESLIEMGFPRGRAEKALALTgNQGIEAAMDWLMEH 42
           5689********************************987 PP

ULD/UDP/UFD/UBX

   S: 2    tteqatlqiRlpdGkrlvrkFpssttleqiyqfve....yllvessdpFeLvspfPrrtlkpeehmstlqeagLvpsgsllv 79
           +++q+++q+RlpdG  l+++F+++++l +++ +ve    ++ +  +dp +L+s+fPrr +++ ++++ lqe+gLvps++l+v
   Q: 209  EYDQCRIQVRLPDGTSLTQTFRAREQLAAVRLYVElhrgEEPGGGQDPVQLLSGFPRRAFSEADMERPLQELGLVPSAVLIV 290
           578*****************************************************************************98 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MAELTALESL IEMGFPRGRA EKALALTGNQ GIEAAMDWLM EHEDDPDVDE PLETPLGHIL 60
GREPTSSEQG GLEGSGSAAG EGKPVLSEEE RQEQTKRMLE LVAQKREREE REEREALERE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTTCCCCT CGGCTTTCTT CTCGTCTGTA TTCCCGGCTG CTATAGAGCC GGGTTAGAGA 60
GCGAGCGCCC GTCCGCGGGC GTCGAGGGCG GGTTGCCTCG CGCTGACCCT TCCCGCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015940--UBA
IPR009060--UBA-like
IPR029071--Ubiquitin-rel_dom
IPR001012--UBX_dom

PROSITE

PS50030--UBA
PS50033--UBX

Pfam

PF00627--UBA
PF00789--UBX

SMART

SM00165--UBA
SM00166--UBX

Gene Ontology

GO:0005829--C:cytosol
GO:0000502--C:proteasome complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:1904293--P:negative regulation of ERAD pathway
GO:0032435--P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:1903094--P:negative regulation of protein K48-linked deubiquitination
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000157--P:negative regulation of ubiquitin-specific protease activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002325	Ailuropoda melanoleuca	91.84	4.00e-113	400.00
IUUC-Aca-004329	Anolis carolinensis	72.12	5.00e-48	183.00
IUUC-Aly-005639	Arabidopsis lyrata	50.91	7.00e-12	65.10
IUUC-Ath-006887	Arabidopsis thaliana	41.67	4.00e-12	65.50
IUUC-Ago-007989	Ashbya gossypii	37.18	9.00e-07	47.40
IUUC-Ame-011399	Astyanax mexicanus	50.16	1.00e-59	222.00
IUUC-Bta-013151	Bos taurus	86.82	1.00e-116	412.00
IUUC-Bol-016537	Brassica oleracea	50.91	1.00e-11	64.30
IUUC-Bra-017906	Brassica rapa	59.09	2.00e-11	63.90
IUUC-Cel-018300	Caenorhabditis elegans	34.85	4.00e-13	68.60
IUUC-Cja-019084	Callithrix jacchus	97.89	1.00e-104	372.00
IUUC-Cfa-020997	Canis familiaris	88.73	2.00e-90	325.00
IUUC-Cpo-021736	Cavia porcellus	79.05	8.00e-82	296.00
IUUC-Cre-022686	Chlamydomonas reinhardtii	40.43	1.00e-07	52.00
IUUC-Csa-024040	Chlorocebus sabaeus	92.26	2.00e-103	368.00
IUUC-Cho-024543	Choloepus hoffmanni	85.64	1.00e-63	236.00
IUUC-Cin-025719	Ciona intestinalis	35.26	6.00e-35	140.00
IUUC-Csv-025854	Ciona savignyi	45.56	2.00e-19	89.70
IUUC-Cme-027235	Cyanidioschyzon merolae	47.73	4.00e-08	52.80
IUUC-Dre-027745	Danio rerio	51.66	1.00e-57	216.00
IUUC-Dno-029598	Dasypus novemcinctus	86.87	2.00e-104	371.00
IUUC-Dor-030917	Dipodomys ordii	80.92	1.00e-89	322.00
IUUC-Dme-032055	Drosophila melanogaster	43.64	2.00e-23	103.00
IUUC-Ete-032960	Echinops telfairi	67.02	1.00e-70	259.00
IUUC-Eca-034294	Equus caballus	87.21	4.00e-107	380.00
IUUC-Eeu-034906	Erinaceus europaeus	83.86	2.00e-97	348.00
IUUC-Fca-035653	Felis catus	84.51	4.00e-96	344.00
IUUC-Gmo-038755	Gadus morhua	45.48	2.00e-51	195.00
IUUC-Gac-042481	Gasterosteus aculeatus	53.87	2.00e-56	212.00
IUUC-Ggo-044821	Gorilla gorilla	91.20	2.00e-96	345.00
IUUC-Hsa-046797	Homo sapiens	91.58	9.00e-105	372.00
IUUC-Itr-048850	Ictidomys tridecemlineatus	88.55	1.00e-114	405.00
IUUC-Lch-049508	Latimeria chalumnae	67.37	7.00e-33	134.00
IUUC-Laf-053932	Loxodonta africana	87.88	3.00e-124	437.00
IUUC-Mcc-055300	Macaca mulatta	91.92	4.00e-103	367.00
IUUC-Mtr-058774	Medicago truncatula	50.00	8.00e-10	57.40
IUUC-Mvi-060245	Microbotryum violaceum	40.48	3.00e-12	65.90
IUUC-Mmr-060979	Microcebus murinus	93.94	2.00e-107	381.00
IUUC-Mdo-062299	Monodelphis domestica	79.58	7.00e-91	326.00
IUUC-Mmu-063212	Mus musculus	86.53	1.00e-109	389.00
IUUC-Mac-065072	Musa acuminata	60.53	1.00e-10	60.50
IUUC-Mpu-066540	Mustela putorius furo	91.92	3.00e-115	407.00
IUUC-Mlu-067589	Myotis lucifugus	84.18	1.00e-105	375.00
IUUC-Nle-069045	Nomascus leucogenys	97.23	3.00e-76	278.00
IUUC-Opr-070772	Ochotona princeps	80.20	2.00e-87	315.00
IUUC-Ont-072006	Oreochromis niloticus	48.41	9.00e-57	213.00
IUUC-Oan-073244	Ornithorhynchus anatinus	87.34	8.00e-36	143.00
IUUC-Ocu-074333	Oryctolagus cuniculus	88.22	4.00e-106	377.00
IUUC-Oba-075451	Oryza barthii	50.94	4.00e-11	62.40
IUUC-Obr-076923	Oryza brachyantha	55.10	2.00e-11	63.90
IUUC-Ogl-077259	Oryza glaberrima	38.36	4.00e-10	59.30
IUUC-Ogu-078589	Oryza glumaepatula	50.94	4.00e-11	62.40
IUUC-Oin-079151	Oryza indica	50.94	4.00e-11	62.40
IUUC-Ome-081253	Oryza meridionalis	50.94	4.00e-11	62.80
IUUC-Oni-082110	Oryza nivara	38.36	1.00e-10	60.50
IUUC-Opu-083336	Oryza punctata	50.94	4.00e-11	62.40
IUUC-Oru-085235	Oryza rufipogon	50.94	4.00e-11	62.40
IUUC-Osa-085611	Oryza sativa	50.94	4.00e-11	62.40
IUUC-Ola-086781	Oryzias latipes	52.75	3.00e-54	205.00
IUUC-Oga-088429	Otolemur garnettii	89.56	4.00e-105	374.00
IUUC-Oar-089885	Ovis aries	86.49	8.00e-117	412.00
IUUC-Ptr-091315	Pan troglodytes	90.85	3.00e-96	344.00
IUUC-Pan-092885	Papio anubis	92.26	2.00e-103	368.00
IUUC-Psi-093299	Pelodiscus sinensis	65.70	4.00e-61	227.00
IUUC-Pma-094221	Petromyzon marinus	64.37	2.00e-28	117.00
IUUC-Ppa-095484	Physcomitrella patens	51.11	2.00e-10	60.10
IUUC-Pfo-096188	Poecilia formosa	52.60	9.00e-54	203.00
IUUC-Pop-098863	Populus trichocarpa	52.94	1.00e-11	64.30
IUUC-Pca-100977	Procavia capensis	86.17	5.00e-98	350.00
IUUC-Ppe-101243	Prunus persica	47.06	8.00e-10	57.80
IUUC-Pva-102169	Pteropus vampyrus	94.37	5.00e-99	353.00
IUUC-Rno-105459	Rattus norvegicus	86.53	2.00e-109	388.00
IUUC-Sha-107526	Sarcophilus harrisii	82.15	4.00e-90	324.00
IUUC-Ssl-108389	Sclerotinia sclerotiorum	25.74	2.00e-05	43.50
IUUC-Sit-110434	Setaria italica	37.80	2.00e-09	56.60
IUUC-Sar-112945	Sorex araneus	83.98	4.00e-64	237.00
IUUC-Sbi-114159	Sorghum bicolor	33.33	2.00e-10	59.30
IUUC-Ssc-116114	Sus scrofa	87.88	3.00e-102	364.00
IUUC-Tru-117839	Takifugu rubripes	51.62	3.00e-52	198.00
IUUC-Tsy-118813	Tarsius syrichta	94.31	9.00e-56	210.00
IUUC-Tni-120504	Tetraodon nigroviridis	49.34	1.00e-52	199.00
IUUC-Tbe-128034	Tupaia belangeri	94.37	1.00e-105	375.00
IUUC-Ttr-128468	Tursiops truncatus	88.85	1.00e-103	369.00
IUUC-Uma-129569	Ustilago maydis	34.62	1.00e-05	43.50
IUUC-Vpa-130179	Vicugna pacos	80.09	4.00e-70	257.00
IUUC-Xtr-132119	Xenopus tropicalis	61.74	6.00e-68	250.00
IUUC-Xma-134067	Xiphophorus maculatus	51.95	7.00e-54	203.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence