iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sit-110624

Ensembl Protein ID

Si001249m

UniProt Accession

K3XH78; K3XH78_SETIT

Genbank Protein ID

KQL03665.1

Protein Name

Presenilin

Genbank Nucleotide ID

CM003532

Gene Name

LOC101778272; SETIT_001249mg

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Si001249m.g	Si001249m	Si001249m

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	29.97	4.00e-30	129.00	IUUC-Cel-018553

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Setaria italica

Functional Description
(View)

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

Protein Sequence
(Fasta)

MDPAASPASA PAPAAEDPLS AASVLDTLGA EVLAVMSPVS ICMALVVLLI SLLSPPSSGP 60
AGASPPPVTA ATLVYLESPN DTPAQKFLGA LLDAAVFVAL VAVVTFVLVA LYYYRCTGFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCTCCCCT CTCCGTCTCC CCCTCCGCAG CATGGATCCC GCCGCCTCGC CGGCGTCGGC 60
GCCGGCGCCC GCTGCGGAGG ATCCCCTAAG CGCCGCCTCC GTGCTCGACA CCCTCGGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0256--Endoplasmic reticulum
KW-0333--Golgi apparatus
KW-0378--Hydrolase
KW-0472--Membrane
KW-0914--Notch signaling pathway
KW-0645--Protease
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001108--Peptidase_A22A
IPR006639--Preselin/SPP

Pfam

PF01080--Presenilin

PRINTS

PR01072--PRESENILIN

SMART

SM00730--PSN

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0005798--C:Golgi-associated vesicle
GO:0016021--C:integral component of membrane
GO:0004190--F:aspartic-type endopeptidase activity
GO:0007219--P:Notch signaling pathway
GO:0016485--P:protein processing

KEGG

sita:101778272

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000686	Aegilops tauschii	75.92	5.00e-124	437.00
IUUC-Aml-001648	Ailuropoda melanoleuca	34.17	2.00e-32	132.00
IUUC-Atr-003039	Amborella trichopoda	51.46	2.00e-103	368.00
IUUC-Apl-003727	Anas platyrhynchos	32.93	2.00e-28	119.00
IUUC-Aca-004582	Anolis carolinensis	32.42	7.00e-19	87.80
IUUC-Aly-005455	Arabidopsis lyrata	56.52	2.00e-56	212.00
IUUC-Ath-006730	Arabidopsis thaliana	55.65	5.00e-57	214.00
IUUC-Ame-011500	Astyanax mexicanus	32.91	1.00e-25	110.00
IUUC-Bta-013026	Bos taurus	31.86	1.00e-30	126.00
IUUC-Bdi-014196	Brachypodium distachyon	80.69	8.00e-149	519.00
IUUC-Bol-015841	Brassica oleracea	50.31	3.00e-92	331.00
IUUC-Bra-017580	Brassica rapa	59.07	3.00e-42	165.00
IUUC-Cel-018553	Caenorhabditis elegans	32.25	9.00e-38	150.00
IUUC-Cja-019994	Callithrix jacchus	32.88	6.00e-19	88.20
IUUC-Cfa-020074	Canis familiaris	31.78	1.00e-30	126.00
IUUC-Cpo-022237	Cavia porcellus	32.74	1.00e-29	123.00
IUUC-Cre-022747	Chlamydomonas reinhardtii	43.16	5.00e-40	158.00
IUUC-Csa-023537	Chlorocebus sabaeus	33.03	2.00e-19	89.70
IUUC-Cho-024735	Choloepus hoffmanni	42.42	2.00e-18	86.30
IUUC-Cin-025780	Ciona intestinalis	35.75	5.00e-21	94.70
IUUC-Csv-025967	Ciona savignyi	32.73	1.00e-20	93.60
IUUC-Dre-028526	Danio rerio	30.92	5.00e-32	131.00
IUUC-Dno-029758	Dasypus novemcinctus	32.58	1.00e-18	87.00
IUUC-Dor-030609	Dipodomys ordii	39.13	2.00e-18	86.30
IUUC-Dme-031929	Drosophila melanogaster	35.29	6.00e-25	108.00
IUUC-Ete-032487	Echinops telfairi	59.26	6.00e-12	64.70
IUUC-Eca-033391	Equus caballus	28.74	6.00e-17	80.90
IUUC-Eeu-035134	Erinaceus europaeus	34.45	1.00e-28	119.00
IUUC-Fca-036243	Felis catus	32.37	4.00e-30	125.00
IUUC-Fal-036600	Ficedula albicollis	31.40	5.00e-26	111.00
IUUC-Gmo-039665	Gadus morhua	34.12	8.00e-19	87.40
IUUC-Gga-040993	Gallus gallus	31.92	5.00e-30	124.00
IUUC-Gac-042511	Gasterosteus aculeatus	32.79	1.00e-20	93.60
IUUC-Gma-043822	Glycine max	62.77	7.00e-44	170.00
IUUC-Ggo-045338	Gorilla gorilla	35.75	3.00e-24	105.00
IUUC-Hsa-046822	Homo sapiens	33.03	2.00e-19	89.70
IUUC-Hvu-047141	Hordeum vulgare	76.86	9.00e-133	466.00
IUUC-Itr-048420	Ictidomys tridecemlineatus	34.22	1.00e-30	125.00
IUUC-Lch-049946	Latimeria chalumnae	34.32	3.00e-18	85.50
IUUC-Lpe-051132	Leersia perrieri	85.09	5.00e-153	533.00
IUUC-Loc-052427	Lepisosteus oculatus	32.96	9.00e-22	97.40
IUUC-Laf-053979	Loxodonta africana	44.09	1.00e-16	80.10
IUUC-Mcc-055682	Macaca mulatta	33.03	2.00e-19	89.70
IUUC-Meu-056004	Macropus eugenii	41.41	6.00e-18	84.70
IUUC-Mtr-058392	Medicago truncatula	52.58	2.00e-94	338.00
IUUC-Mga-059466	Meleagris gallopavo	31.47	5.00e-30	124.00
IUUC-Mmr-060890	Microcebus murinus	36.31	6.00e-25	107.00
IUUC-Mdo-062197	Monodelphis domestica	36.31	9.00e-26	110.00
IUUC-Mmu-063176	Mus musculus	32.13	5.00e-19	88.20
IUUC-Mac-064858	Musa acuminata	85.05	3.00e-46	178.00
IUUC-Mpu-065927	Mustela putorius furo	31.92	1.00e-30	127.00
IUUC-Mlu-067079	Myotis lucifugus	32.89	1.00e-34	140.00
IUUC-Nle-070180	Nomascus leucogenys	33.03	2.00e-19	89.70
IUUC-Opr-070344	Ochotona princeps	35.75	7.00e-23	101.00
IUUC-Ont-071846	Oreochromis niloticus	32.96	6.00e-18	84.70
IUUC-Oan-072783	Ornithorhynchus anatinus	41.41	1.00e-17	83.20
IUUC-Ocu-074527	Oryctolagus cuniculus	33.67	8.00e-31	127.00
IUUC-Oba-075256	Oryza barthii	81.32	2.00e-127	447.00
IUUC-Obr-076302	Oryza brachyantha	84.78	6.00e-148	516.00
IUUC-Ogl-077097	Oryza glaberrima	79.83	2.00e-143	501.00
IUUC-Ogu-078570	Oryza glumaepatula	82.24	2.00e-138	484.00
IUUC-Oin-079244	Oryza indica	79.40	8.00e-143	499.00
IUUC-Olo-080484	Oryza longistaminata	78.41	3.00e-103	367.00
IUUC-Ome-081814	Oryza meridionalis	82.01	3.00e-148	517.00
IUUC-Oni-082057	Oryza nivara	82.00	8.00e-138	482.00
IUUC-Opu-084176	Oryza punctata	81.27	3.00e-137	480.00
IUUC-Oru-084618	Oryza rufipogon	82.24	3.00e-138	484.00
IUUC-Osa-085602	Oryza sativa	82.13	2.00e-139	488.00
IUUC-Ola-086707	Oryzias latipes	33.15	1.00e-23	103.00
IUUC-Olu-087811	Ostreococcus lucimarinus	42.99	3.00e-36	145.00
IUUC-Oga-088560	Otolemur garnettii	35.75	2.00e-24	106.00
IUUC-Oar-090348	Ovis aries	31.11	3.00e-32	132.00
IUUC-Ptr-091060	Pan troglodytes	33.03	2.00e-19	89.70
IUUC-Pan-091742	Papio anubis	35.75	3.00e-24	105.00
IUUC-Psi-093505	Pelodiscus sinensis	32.13	6.00e-19	88.20
IUUC-Pma-094612	Petromyzon marinus	35.51	1.00e-20	94.00
IUUC-Ppa-095431	Physcomitrella patens	43.55	4.00e-85	307.00
IUUC-Pfo-097396	Poecilia formosa	30.77	4.00e-31	128.00
IUUC-Pab-098591	Pongo abelii	33.03	2.00e-19	89.70
IUUC-Pop-099661	Populus trichocarpa	44.35	1.00e-75	276.00
IUUC-Pca-101029	Procavia capensis	50.00	4.00e-12	65.50
IUUC-Ppe-101495	Prunus persica	55.32	9.00e-106	376.00
IUUC-Pva-102934	Pteropus vampyrus	34.08	3.00e-23	102.00
IUUC-Rno-105861	Rattus norvegicus	32.58	4.00e-19	88.60
IUUC-Sha-106876	Sarcophilus harrisii	35.75	3.00e-25	108.00
IUUC-Smo-109325	Selaginella moellendorffii	48.25	3.00e-38	152.00
IUUC-Sly-110865	Solanum lycopersicum	88.57	8.00e-33	131.00
IUUC-Stu-112433	Solanum tuberosum	51.91	2.00e-95	342.00
IUUC-Sar-113169	Sorex araneus	43.43	7.00e-19	87.80
IUUC-Sbi-114305	Sorghum bicolor	92.47	2.00e-175	607.00
IUUC-Ssc-115766	Sus scrofa	31.47	6.00e-30	124.00
IUUC-Tgu-116469	Taeniopygia guttata	31.08	4.00e-28	117.00
IUUC-Tru-117732	Takifugu rubripes	29.88	5.00e-29	121.00
IUUC-Tsy-119303	Tarsius syrichta	63.64	3.00e-05	42.70
IUUC-Tni-119852	Tetraodon nigroviridis	30.12	8.00e-27	114.00
IUUC-Tca-121865	Theobroma cacao	54.61	1.00e-99	356.00
IUUC-Tae-125925	Triticum aestivum	77.02	3.00e-131	461.00
IUUC-Tur-126237	Triticum urartu	75.13	2.00e-118	418.00
IUUC-Tbe-127632	Tupaia belangeri	35.75	2.00e-24	105.00
IUUC-Ttr-128793	Tursiops truncatus	34.45	1.00e-28	120.00
IUUC-Vpa-130625	Vicugna pacos	42.27	6.00e-18	84.70
IUUC-Vvi-131312	Vitis vinifera	64.78	1.00e-54	206.00
IUUC-Xtr-132756	Xenopus tropicalis	34.08	6.00e-24	104.00
IUUC-Xma-133377	Xiphophorus maculatus	32.96	1.00e-17	83.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence