iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011064

Ensembl Protein ID

ENSAMXP00000015870.1

UniProt Accession

W5L7Q8; W5L7Q8_ASTMX

Genbank Protein ID

ENSAMXP00000015870

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01098988

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000015361.1	ENSAMXT00000015870.1	ENSAMXP00000015870.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.00e-115	386.8	321	984
ULD/UDP/UBQ/UBQ_Other	2.00e-10	40.7	166	238

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn p+l+e++le +++ ++n+enp ++ ge+++++++l++++w s++++v+pr+++++++++a++fsgy+
   Q: 321  CGLSNLGNTCFMNSALQCLSNSPPLTEYFLEdQYEAEINRENPLGMRGEIAEAYADLVKQMWLSRSSYVAPRTFKTQVGRFAPQFSGYQ 409
           7******************************99******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+  +++++   ++de     a+ ++  +n+s+i+d+F+g +ks+++c+ec +vs++++pf++l
   Q: 410  QQDSQELLAFLLDGLHEDLNRVKKKPYLALRDAE--GRPDEivakeAWTNHRLRNDSIIVDIFHGLFKSTLVCPECSKVSVTFDPFCYL 496
           ***************************9998887..6666667777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+++ +e                                                                            
   Q: 497  TLPLPMKKDRTMEvilvcadplsrptkyrvvvpkigtvadlcsalsklsgvpaenmvvadvynhrfhkiyrkeeglnhivdkdiifiye 585
           ********99999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 586  vleedsermnlpvyfrerhmkhsggssgtmlfgqpllvtvprhnlsqdtlyervlerigryvkrsqgtvvdsrasasatscnsshsvdc 674
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 675  gvsasnhsagvsscsspmsdgascsagstngssshsetcngpngvcdgeveamdhqdspdpessqsetvdgedegsepengpvasvgka 763
           ***************************************************************************************** PP
   S: 186  ..........................................................................slqdcLesftkeeel 200
                                                                                      l++c+e ft+ e+l
   Q: 764  srpklftfsmvntygtanisplpcegnilkltphstiaidweadskrlcyddqeaeayekhesmmqaqkkkttvALKECIELFTTMETL 852
           ***************************************************************************************** PP
   S: 201  egenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG 288
            +++ +yc++ckk+q+a+kk++l++lP++L++hLkRfs+++  + r k+++ v+fp++ L++s+f+++p+ +   ++ Y+L+av +H+G
   Q: 853  GEHDPWYCPTCKKHQRATKKFDLWSLPRILVVHLKRFSYNR--CWRDKLDTIVDFPIRdLNMSEFVCDPKAA---PYVYDLVAVSNHYG 936
           *************************************9966..6778*********************9976...9************* PP
   S: 289  slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++++GHY+ay+kn+ ++ W++fdDs+V++ +e+++++   + aYvlfY+rr
   Q: 937  GMGGGHYTAYAKNKADGkWYYFDDSSVSSASEDQIVT---KAAYVLFYQRR 984
           *************65445*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 11   s.eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
             + t++++++dt+ ++ ++++++++ip + + rL++k      + L ++d t++d gl++g+++++++k+++
   Q: 166  DnVVTRHFSKADTIDTIEKEMRSLFNIPsEKETRLWNKymsntYEQLnKPDSTVQDAGLFQGQVLVIERKNED 238
           3478999*********************777*****999987744457*******************999876 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

TMAEGGGPES GNASDPDAEP GPAQAAVPSI DSQKQTIGSS LKTTLRKGDE WFLIDSRWFK 60
QWKKYVGFDS WDMYNVGEHN LYPGPIDNSG LFSDQETQAL KDHLIDELDY VLVPTEAWNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGATGGCGG AGGGAGGCGG ACCCGAGTCG GGGAACGCTT CGGACCCTGA TGCGGAGCCC 60
GGGCCGGCTC AAGCGGCGGT ACCTTCTATC GACAGTCAAA AACAGACGAT AGGATCATCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034122--P:negative regulation of toll-like receptor signaling pathway
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004068	Anas platyrhynchos	61.46	0.00e+00	1092.00
IUUC-Aca-004459	Anolis carolinensis	64.01	0.00e+00	793.00
IUUC-Aly-006315	Arabidopsis lyrata	49.19	3.00e-79	290.00
IUUC-Ath-007343	Arabidopsis thaliana	38.63	3.00e-106	379.00
IUUC-Ago-007911	Ashbya gossypii	41.11	1.00e-65	245.00
IUUC-Ate-010323	Aspergillus terreus	37.23	4.00e-55	210.00
IUUC-Bgr-012277	Blumeria graminis	45.88	1.00e-63	239.00
IUUC-Bta-012929	Bos taurus	64.19	0.00e+00	1224.00
IUUC-Bci-013993	Botrytis cinerea	45.36	6.00e-66	246.00
IUUC-Bdi-015062	Brachypodium distachyon	41.21	9.00e-128	451.00
IUUC-Bol-015244	Brassica oleracea	36.23	6.00e-150	525.00
IUUC-Bra-016885	Brassica rapa	35.91	5.00e-147	515.00
IUUC-Cfa-020599	Canis familiaris	64.79	0.00e+00	1226.00
IUUC-Cpo-022144	Cavia porcellus	65.57	0.00e+00	1200.00
IUUC-Csa-023770	Chlorocebus sabaeus	65.84	0.00e+00	1143.00
IUUC-Cho-024595	Choloepus hoffmanni	60.15	0.00e+00	763.00
IUUC-Csv-026109	Ciona savignyi	46.46	1.00e-148	520.00
IUUC-Dre-027869	Danio rerio	85.00	0.00e+00	1623.00
IUUC-Dno-029316	Dasypus novemcinctus	64.82	0.00e+00	1231.00
IUUC-Ete-032970	Echinops telfairi	62.48	0.00e+00	756.00
IUUC-Fca-035373	Felis catus	68.05	0.00e+00	889.00
IUUC-Fox-037986	Fusarium oxysporum	39.32	4.00e-63	237.00
IUUC-Gmo-038866	Gadus morhua	84.45	0.00e+00	973.00
IUUC-Gga-040729	Gallus gallus	59.90	0.00e+00	1090.00
IUUC-Gac-042631	Gasterosteus aculeatus	89.03	0.00e+00	1095.00
IUUC-Lch-050533	Latimeria chalumnae	65.69	0.00e+00	1175.00
IUUC-Lpe-051185	Leersia perrieri	41.80	4.00e-127	449.00
IUUC-Loc-051800	Lepisosteus oculatus	78.16	0.00e+00	1530.00
IUUC-Mcc-055556	Macaca mulatta	62.13	0.00e+00	1141.00
IUUC-Mpo-057486	Magnaporthe poae	45.49	7.00e-62	233.00
IUUC-Mla-058848	Melampsora laricipopulina	42.34	5.00e-70	260.00
IUUC-Mga-059300	Meleagris gallopavo	60.47	0.00e+00	1064.00
IUUC-Mac-064956	Musa acuminata	39.08	3.00e-110	393.00
IUUC-Mpu-066920	Mustela putorius furo	65.16	0.00e+00	1226.00
IUUC-Mlu-068088	Myotis lucifugus	64.28	0.00e+00	1208.00
IUUC-Ncr-068879	Neurospora crassa	47.14	1.00e-61	232.00
IUUC-Nle-070010	Nomascus leucogenys	64.65	0.00e+00	1216.00
IUUC-Ont-072573	Oreochromis niloticus	81.50	0.00e+00	1550.00
IUUC-Oan-073363	Ornithorhynchus anatinus	63.04	0.00e+00	847.00
IUUC-Ocu-074242	Oryctolagus cuniculus	61.54	0.00e+00	1127.00
IUUC-Ola-086553	Oryzias latipes	78.25	0.00e+00	1480.00
IUUC-Oga-088562	Otolemur garnettii	60.60	0.00e+00	1095.00
IUUC-Oar-090439	Ovis aries	65.08	0.00e+00	1222.00
IUUC-Psi-093942	Pelodiscus sinensis	64.44	0.00e+00	860.00
IUUC-Pfo-097060	Poecilia formosa	80.80	0.00e+00	1511.00
IUUC-Pgr-103546	Puccinia graminis	27.93	2.00e-82	301.00
IUUC-Sly-111746	Solanum lycopersicum	37.09	3.00e-153	535.00
IUUC-Stu-112671	Solanum tuberosum	36.92	2.00e-150	526.00
IUUC-Sbi-114031	Sorghum bicolor	39.46	3.00e-122	432.00
IUUC-Ssc-115637	Sus scrofa	68.56	0.00e+00	881.00
IUUC-Tru-118634	Takifugu rubripes	84.90	0.00e+00	1009.00
IUUC-Tni-120107	Tetraodon nigroviridis	73.53	0.00e+00	993.00
IUUC-Tme-127062	Tuber melanosporum	29.83	5.00e-75	276.00
IUUC-Tbe-127669	Tupaia belangeri	50.08	1.00e-168	587.00
IUUC-Ttr-128778	Tursiops truncatus	63.67	0.00e+00	1193.00
IUUC-Uma-129498	Ustilago maydis	41.39	2.00e-71	264.00
IUUC-Vvi-131010	Vitis vinifera	37.38	8.00e-147	514.00
IUUC-Xtr-132305	Xenopus tropicalis	64.31	0.00e+00	1223.00
IUUC-Xma-133176	Xiphophorus maculatus	80.53	0.00e+00	1373.00
IUUC-Yli-134392	Yarrowia lipolytica	44.96	4.00e-64	240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence