iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132459

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 35

Genbank Nucleotide ID

AAMC01111621

Gene Name

klhl35

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000015058.3	ENSXETT00000032952.3	ENSXETP00000032952.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	8.70e-18	64.6	21	86
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	4.10e-06	26.1	89	118

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D++lv++g+ +++hk++L+++Ss+F+a+f ++l+es+  + vei+ ++  v+ +ll+++Y g+l +
   Q: 21   TDIVLVIDGRDYPCHKAILSSCSSYFRAMFGGHLKESQ-LDIVEIQNISSPVMDVLLEYMYGGSLLI 86
           79***********************************9.************************9866 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
           +N++gil ++dl+   +L+da+++f++++ 
   Q: 89   DNVVGILEASDLLHMNKLRDACVKFLENQL 118
           8*************************9985 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

SCHALDILQS LNIYRKTGVF TDIVLVIDGR DYPCHKAILS SCSSYFRAMF GGHLKESQLD 60
IVEIQNISSP VMDVLLEYMY GGSLLIEEDN VVGILEASDL LHMNKLRDAC VKFLENQLHP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCATGCCATG CACTGGATAT CCTGCAGAGT TTAAATATTT ACAGAAAAAC AGGGGTGTTC 60
ACGGATATCG TCCTTGTTAT CGACGGAAGG GATTACCCCT GCCATAAAGC GATCCTGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030601--KLHL35
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003919	Anas platyrhynchos	69.34	0.00e+00	802.00
IUUC-Aca-004292	Anolis carolinensis	60.58	0.00e+00	688.00
IUUC-Bta-012754	Bos taurus	51.80	1.00e-157	549.00
IUUC-Bol-016582	Brassica oleracea	30.00	8.00e-12	65.90
IUUC-Bra-017771	Brassica rapa	30.22	7.00e-12	65.90
IUUC-Cja-019390	Callithrix jacchus	50.99	4.00e-150	524.00
IUUC-Cfa-021181	Canis familiaris	51.44	1.00e-156	546.00
IUUC-Dno-028982	Dasypus novemcinctus	51.52	3.00e-162	565.00
IUUC-Dse-031351	Dothistroma septosporum	33.33	4.00e-07	48.10
IUUC-Gga-041027	Gallus gallus	68.74	0.00e+00	795.00
IUUC-Ggo-045055	Gorilla gorilla	52.15	4.00e-158	551.00
IUUC-Hsa-046044	Homo sapiens	57.27	2.00e-145	508.00
IUUC-Itr-048569	Ictidomys tridecemlineatus	52.99	4.00e-174	604.00
IUUC-Lch-050580	Latimeria chalumnae	61.09	0.00e+00	718.00
IUUC-Loc-052921	Lepisosteus oculatus	54.48	2.00e-166	578.00
IUUC-Laf-053674	Loxodonta africana	49.73	9.00e-152	530.00
IUUC-Mga-059938	Meleagris gallopavo	68.92	0.00e+00	794.00
IUUC-Mdo-062790	Monodelphis domestica	54.40	1.00e-167	583.00
IUUC-Mmu-064185	Mus musculus	53.26	2.00e-161	562.00
IUUC-Mpu-065712	Mustela putorius furo	51.61	3.00e-169	588.00
IUUC-Ncr-068938	Neurospora crassa	34.33	3.00e-08	53.50
IUUC-Ocu-074956	Oryctolagus cuniculus	51.44	1.00e-175	609.00
IUUC-Oga-088752	Otolemur garnettii	51.32	2.00e-155	541.00
IUUC-Ptr-091651	Pan troglodytes	57.05	2.00e-145	508.00
IUUC-Psi-093093	Pelodiscus sinensis	70.31	0.00e+00	817.00
IUUC-Rno-105037	Rattus norvegicus	53.26	2.00e-161	562.00
IUUC-Sha-106719	Sarcophilus harrisii	54.44	2.00e-169	588.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence