iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndex
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	9.40e-06	26.8	69	142

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    Dvilvvg.geeffahkivLaasSsvFyalflmeleesksklmveik..d......vqpevfrallkFlYtgklde 67
           D  lv++ g+e++ h+++L+a+ +vF++ + +  +e+ks+ +v+++  +      v  +++ a+l ++Y+g+++ 
   Q: 69   DAKLVLAgGREVSFHRCILSARIPVFKSALAT-VKEQKSSTTVKLQlkEiardyeVGFDSVVAVLAYVYSGRVRS 142
           88999998**********************65.555556777776665355458899999************976 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex (CUL3-RBX1-BTB) which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Protein Sequence
(Fasta)

MMATTTTTTT ARFSDSYEFS NTSGNSFFAA ESSLDYPTEF LTPPEVSALK LLSNCLESVF 60
DSPETFYSDA KLVLAGGREV SFHRCILSAR IPVFKSALAT VKEQKSSTTV KLQLKEIARD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATTTGACG TAATATATTC CGTTTTAAGA AACCTATCTA GTTTCCAAGA AATTTACTAA 60
TAAAGGTGCT TGAGAAAGAC CGTTGTTGAT GATACGTTTT TTTATTTGCT AATGAAACGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0702--S-nitrosylation
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR000210--BTB/POZ_dom
IPR021094--NPR1/NIM1-like_C
IPR024228--NPR_central_dom
IPR011333--SKP1/BTB/POZ

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50097--BTB

Pfam

PF00023--Ank
PF00651--BTB
PF11900--DUF3420
PF12313--NPR1_like_C

SMART

SM00248--ANK
SM00225--BTB

Gene Ontology

GO:0016567--P:protein ubiquitination
GO:0010200--P:response to chitin

KEGG

ath:AT4G26120

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005991	Arabidopsis lyrata	90.37	0.00e+00	1048.00
IUUC-Bol-016455	Brassica oleracea	72.57	0.00e+00	827.00
IUUC-Bra-016815	Brassica rapa	71.72	0.00e+00	811.00
IUUC-Eca-033590	Equus caballus	33.33	1.00e-03	38.50
IUUC-Mla-058986	Melampsora laricipopulina	29.21	5.70e-02	31.60

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence