iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011260

Ensembl Protein ID

ENSAMXP00000006604.1

UniProt Accession

W5KG92; W5KG92_ASTMX

Genbank Protein ID

ENSAMXP00000006604

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

APWO01024090

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000006436.1	ENSAMXT00000006604.1	ENSAMXP00000006604.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.90e-09	36.5	183	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C + + +e  ++ C++  C  ewfH+aC+ l+   ++p+ e w+Cp+C 
   Q: 183  TYC-LCSQVSYGE--MIGCDNadCPiEWFHFACVDLT---TKPKGE-WFCPRCV 229
           69*.*******99..******99*99***********...999998.******6 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MATAMYLEHY LDSIEGLPFE LQRNFSLMTD LDNRTELKKV EIDNLAAEYT AKVKNLSSEE 60
RMEHLKRIEN AYDQCREFSD DKVLLAMQIY EMVDKHIRRL DADLARFESE LKDKLDSSGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGACCAGAG CTTGTGAAGG TAGGAGTCGG TCAATGTGAT ATGTGTATCA GGTAAACATC 60
ACTGAGCTCG CCTGTATGAA CTCAGAGCGG GTAAAGTTAA CGCGGGCAGA GCAGAAATGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028638--ING5
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Bra-017027	Brassica rapa	33.76	8.00e-30	123.00
IUUC-Dme-032200	Drosophila melanogaster	44.91	9.00e-62	229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence