iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Ath-007515

UUCD1 version

UUC-ArT-01502

Ensembl Protein ID

AT1G20140.1

UniProt Accession

Q9LNT9; ASK4_ARATH

Genbank Protein ID

AAF79899.1; AEE29943.1; AAL25617.1; AAM19990.1

Protein Name

SKP1-like protein 4

Genbank Nucleotide ID

AC022472; CP002684; AY058205; AY098980

Gene Name

ASK4; At1g20140; T20H2.8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT1G20140	AT1G20140.1	AT1G20140.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 adaptor/Cullin RING/SCF/SKP1	SKP1	12169662; 12795696; 16983093

Classification

Family	E-value	Score	Start	End
E3 adaptor/Cullin RING/SCF/SKP1	4.50e-30	104.5	115	161

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/SKP1

   S: 2    sLLdltcktVadmikgktpeeiRktFnienDftpeEeakvReEnqWA 48
           +LLdltck+Vad+++gktpe++R++Fni+nD+tpeEea+vR+En+WA
   Q: 115  GLLDLTCKAVADQMRGKTPEQMRAHFNIKNDYTPEEEAEVRNENKWA 161
           7*********************************************9 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1 (By similarity).

Protein Sequence
(Fasta)

MAETKKMIIL KSSDGESFEI EEAVAVKSQT IKHMIEDDCA DNGIPLPNVT GAILAKVIEY 60
CKKHVEAAAE AGGDKDFYGS AENDELKNWD SEFVKVDQPT LFDLILAANY LNIGGLLDLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAATTAAGAA ATTGGCTATA AATAAGGCTC CAACTTCCCA AACCTTGACA CCATCACAAC 60
AATCAATCGC AGCGCCGATT CTCCTTCAAA AACTTTTCCT AAGTCGTCAC TTTTTACGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016897--SKP1
IPR001232--SKP1-like
IPR011333--SKP1/BTB/POZ
IPR016072--Skp1_comp_dimer
IPR016073--Skp1_comp_POZ

Pfam

PF01466--Skp1
PF03931--Skp1_POZ

SMART

SM00512--Skp1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ath:AT1G20140

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000311	Aegilops tauschii	66.07	2.00e-61	227.00
IUUC-Aly-006236	Arabidopsis lyrata	92.41	2.00e-84	303.00
IUUC-Ago-007847	Ashbya gossypii	41.11	8.00e-35	139.00
IUUC-Bdi-014547	Brachypodium distachyon	66.67	2.00e-52	197.00
IUUC-Bra-017558	Brassica rapa	81.76	1.00e-74	271.00
IUUC-Cne-027058	Cryptococcus neoformans	48.17	3.00e-41	160.00
IUUC-Mtr-058056	Medicago truncatula	68.12	2.00e-60	224.00
IUUC-Mla-059153	Melampsora laricipopulina	48.08	2.00e-39	154.00
IUUC-Olo-080619	Oryza longistaminata	56.71	7.00e-49	185.00
IUUC-Pop-099815	Populus trichocarpa	69.33	5.00e-58	215.00
IUUC-Pgr-103499	Puccinia graminis	48.08	6.00e-40	155.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence