iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Atr-003015

Ensembl Protein ID

ERN11851

UniProt Accession

W1PVV9; W1PVV9_AMBTC

Genbank Protein ID

ERN11851.1

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

KI392664

Gene Name

AMTR_s00020p00108940

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AMTR_s00020p00108940	ERN11851	ERN11851

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.50e-78	262.5	258	1045

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeel...............wkskkkavsprellkalkkeaeef 84
           +Gl+NlgNtC++NSvLQ L+++ +lr+ +l+     +n+ n     g+l+++l+klf e                w ++++  +p++l+  ++++a++f
   Q: 258  KGLQNLGNTCFFNSVLQNLLALGSLRDHFLN-----MNHFN----GGPLSSALKKLFCETcfdpsekggpkesknWGQTHGILNPKSLFGNICSKAPQF 347
           5******************************.....44443....589*********999889999889988888899999****************** PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetk 183
           +gy+qqD++E+l++lld+l++e          ++++++ks++ +++e+ + +   s+++ +F+g+l+s++ c ec+++s+ +epfldlslpvp k+ tk
   Q: 348  RGYQQQDSHELLRCLLDALSTED-------LVSKKSAAKSNSGEDEENGPLNVDVSFVDGIFGGRLSSTLCCSECGRSSTVYEPFLDLSLPVPAKKPTK 439
           *******************9766.......344555556666777889999*********************************************888 PP
   S: 184  ke................................................................................................. 185
           k                                                                                                  
   Q: 440  KApiarpkklalgrpgkaslkesrkgrrdqekgnsfigpiwnpsagiglssecsegssvpsnpvvkeeetvapeesvrwldyiedpkedsscvnapees 538
           87************************************************************************************************* PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 539  fcwldyikdpkdgsscldaseskpkcsfshcdgdttkrnpetglvvdnrdtssysaepkhedpkdssleksetnsclpngepkigcdssgddnefiddg 637
           *************************************************************************************************** PP
   S: 186  ................................................................................................... 185
                                                                                                              
   Q: 638  eplvigdsevlllpykemdsteegilsdpqepdtllngyglngdsssvvlgcekgadefdglgdlfnepeivsdpkkepgsggnnmqfidefvtqdlse 736
           *************************************************************************************************** PP
   S: 186  ...............slqdcLesftkeeelegenkyycekck......................................................... 212
                          s++ cL++ftk+e l+g + ++ce c                                                          
   Q: 737  tefnqeevdntdapvSVEICLADFTKPELLTGVHGFNCEGCSkalnhnnnretkvledqvngangsesmeseasldaletqksrlingskgslpfepee 835
           *************************************************************************************************** PP
   S: 213  .................................................................................kkqeaekklklkklPevL 230
                                                                                             k++ +k++ ++k P+vL
   Q: 836  ssinrrlpadvsdcssnldkrgcnesfcaqncddlcssgcdsassrgsdgcnlaekskrekymlsgrtknaekrkdgqmecFKRDGTKRFLISKAPPVL 934
           ******************************************************9999999999999988888877777776666************** PP
   S: 231  ilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.........WllfdDskVtevkee 320
           ++hLkRfs + + ++ +k+n +v+f ++L+l+p++ +++ ++ ++  Y+L++vv HsGs+++GHYvayv+  + +         W++ +D +V+ v+ +
   Q: 935  TIHLKRFSQDAR-GRLSKLNGHVNFREMLELRPYMDRRCPDK-DSSLYSLVGVVEHSGSMRGGHYVAYVRGPHSRdpqglgeysWFYASDVNVSRVSLT 1031
           *******77665.8899********************99876.59**************************4444444555666*************** PP
   S: 321  evleetgstaYvlfYkr 337
           evl+   s+aY+lfY++
   Q: 1032 EVLK---SEAYILFYEK 1045
           ****...********98 PP

Organism

Amborella trichopoda

Protein Sequence
(Fasta)

MGKKLKKRTR HGSGHKDNRP SAVSPLMENH VNQKSKLVEE NTHVSSSKLV EENTQVSSGN 60
LCRHANKAVN FSALSSKNRR LGVIRCEDCS KDSERKERKG KGKQGRNKGL YGENSDSNSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAAA AGCTCAAAAA GAGGACTAGA CATGGGTCTG GGCATAAGGA TAATAGGCCC 60
TCAGCTGTTT CACCTCTAAT GGAGAATCAT GTGAACCAGA AATCCAAATT GGTTGAAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	33.23	9.00e-61	227.00
IUUC-Aml-001931	Ailuropoda melanoleuca	30.86	3.00e-36	145.00
IUUC-Apl-004145	Anas platyrhynchos	29.50	9.00e-38	150.00
IUUC-Aca-004314	Anolis carolinensis	28.75	3.00e-30	125.00
IUUC-Aly-005494	Arabidopsis lyrata	34.54	5.00e-119	421.00
IUUC-Ath-007211	Arabidopsis thaliana	32.40	4.00e-119	421.00
IUUC-Ame-011659	Astyanax mexicanus	42.96	7.00e-27	114.00
IUUC-Bta-013362	Bos taurus	31.38	2.00e-34	139.00
IUUC-Bdi-014465	Brachypodium distachyon	31.54	5.00e-62	231.00
IUUC-Bol-015853	Brassica oleracea	35.59	3.00e-58	219.00
IUUC-Bra-017226	Brassica rapa	32.68	3.00e-79	288.00
IUUC-Cja-019177	Callithrix jacchus	30.71	9.00e-37	147.00
IUUC-Cfa-020051	Canis familiaris	31.82	9.00e-38	150.00
IUUC-Cpo-021886	Cavia porcellus	31.10	5.00e-39	155.00
IUUC-Csa-024103	Chlorocebus sabaeus	30.48	4.00e-36	145.00
IUUC-Cho-024315	Choloepus hoffmanni	49.11	1.00e-19	90.90
IUUC-Cin-025775	Ciona intestinalis	39.01	5.00e-19	85.50
IUUC-Cme-027348	Cyanidioschyzon merolae	36.15	2.00e-17	83.60
IUUC-Dre-028388	Danio rerio	31.74	1.00e-32	134.00
IUUC-Dno-029409	Dasypus novemcinctus	30.58	3.00e-37	149.00
IUUC-Dor-030443	Dipodomys ordii	43.54	2.00e-27	116.00
IUUC-Ete-032807	Echinops telfairi	44.22	5.00e-28	118.00
IUUC-Eca-033479	Equus caballus	39.91	2.00e-30	126.00
IUUC-Eeu-034835	Erinaceus europaeus	41.94	3.00e-27	116.00
IUUC-Fca-036320	Felis catus	30.94	4.00e-37	149.00
IUUC-Fal-037029	Ficedula albicollis	29.43	2.00e-34	140.00
IUUC-Gmo-039228	Gadus morhua	29.85	1.00e-34	140.00
IUUC-Gga-040527	Gallus gallus	30.49	3.00e-36	145.00
IUUC-Gac-042343	Gasterosteus aculeatus	30.39	1.00e-37	150.00
IUUC-Gma-044402	Glycine max	36.50	2.00e-152	531.00
IUUC-Ggo-045598	Gorilla gorilla	29.76	1.00e-34	140.00
IUUC-Hsa-046598	Homo sapiens	29.76	7.00e-35	141.00
IUUC-Hvu-047146	Hordeum vulgare	31.54	2.00e-61	229.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	32.02	3.00e-37	149.00
IUUC-Lch-050536	Latimeria chalumnae	29.00	1.00e-35	144.00
IUUC-Lpe-050703	Leersia perrieri	35.19	1.00e-54	207.00
IUUC-Loc-051814	Lepisosteus oculatus	32.59	1.00e-38	153.00
IUUC-Laf-053732	Loxodonta africana	31.43	8.00e-39	154.00
IUUC-Mcc-054661	Macaca mulatta	30.48	3.00e-36	145.00
IUUC-Meu-055967	Macropus eugenii	41.38	3.00e-19	89.40
IUUC-Mtr-057945	Medicago truncatula	42.14	1.00e-77	283.00
IUUC-Mla-059026	Melampsora laricipopulina	36.57	2.00e-19	89.70
IUUC-Mga-059551	Meleagris gallopavo	30.10	3.00e-41	162.00
IUUC-Mmr-061747	Microcebus murinus	30.73	2.00e-36	146.00
IUUC-Mdo-062220	Monodelphis domestica	30.05	5.00e-38	151.00
IUUC-Mmu-063582	Mus musculus	30.12	4.00e-35	142.00
IUUC-Mac-064941	Musa acuminata	55.14	5.00e-51	194.00
IUUC-Mpu-066339	Mustela putorius furo	32.32	4.00e-37	149.00
IUUC-Mlu-067511	Myotis lucifugus	30.77	9.00e-36	144.00
IUUC-Nle-069252	Nomascus leucogenys	30.24	4.00e-36	145.00
IUUC-Opr-070969	Ochotona princeps	30.57	9.00e-35	140.00
IUUC-Ont-071786	Oreochromis niloticus	28.44	5.00e-36	145.00
IUUC-Oan-073656	Ornithorhynchus anatinus	28.44	1.00e-36	147.00
IUUC-Ocu-074704	Oryctolagus cuniculus	32.31	3.00e-37	149.00
IUUC-Oba-075094	Oryza barthii	34.92	2.00e-55	209.00
IUUC-Obr-076743	Oryza brachyantha	35.82	5.00e-58	218.00
IUUC-Ogl-077739	Oryza glaberrima	34.74	2.00e-55	209.00
IUUC-Ogu-078851	Oryza glumaepatula	34.74	1.00e-54	207.00
IUUC-Oin-079402	Oryza indica	34.74	4.00e-55	208.00
IUUC-Olo-080431	Oryza longistaminata	35.37	4.00e-54	205.00
IUUC-Ome-081580	Oryza meridionalis	34.97	6.00e-54	205.00
IUUC-Oni-082644	Oryza nivara	34.74	4.00e-55	208.00
IUUC-Opu-083452	Oryza punctata	33.38	2.00e-63	236.00
IUUC-Oru-084546	Oryza rufipogon	34.74	6.00e-55	208.00
IUUC-Osa-085858	Oryza sativa	34.74	7.00e-55	208.00
IUUC-Ola-087238	Oryzias latipes	30.04	2.00e-35	142.00
IUUC-Oga-088713	Otolemur garnettii	31.78	7.00e-38	151.00
IUUC-Oar-089887	Ovis aries	31.85	2.00e-35	143.00
IUUC-Ptr-091670	Pan troglodytes	29.76	2.00e-34	140.00
IUUC-Pan-092293	Papio anubis	30.48	3.00e-36	145.00
IUUC-Psi-093101	Pelodiscus sinensis	29.18	7.00e-34	137.00
IUUC-Ppa-095622	Physcomitrella patens	33.95	1.00e-49	191.00
IUUC-Pfo-097202	Poecilia formosa	29.06	6.00e-36	144.00
IUUC-Pab-098539	Pongo abelii	26.84	1.00e-34	140.00
IUUC-Pop-099136	Populus trichocarpa	36.13	4.00e-143	501.00
IUUC-Pca-101069	Procavia capensis	41.29	1.00e-27	117.00
IUUC-Ppe-101794	Prunus persica	38.94	2.00e-83	303.00
IUUC-Pva-103092	Pteropus vampyrus	42.57	1.00e-27	117.00
IUUC-Rno-105237	Rattus norvegicus	29.55	9.00e-35	140.00
IUUC-Sha-106889	Sarcophilus harrisii	31.49	4.00e-36	145.00
IUUC-Spo-108149	Schizosaccharomyces pombe	37.24	2.00e-18	86.70
IUUC-Smo-108942	Selaginella moellendorffii	50.85	1.00e-41	162.00
IUUC-Sit-110283	Setaria italica	32.58	2.00e-64	240.00
IUUC-Sly-111487	Solanum lycopersicum	35.41	5.00e-140	491.00
IUUC-Stu-112820	Solanum tuberosum	41.10	9.00e-84	304.00
IUUC-Sar-113530	Sorex araneus	31.54	6.00e-37	148.00
IUUC-Sbi-113785	Sorghum bicolor	34.04	2.00e-52	200.00
IUUC-Ssc-116091	Sus scrofa	39.91	5.00e-30	125.00
IUUC-Tgu-117478	Taeniopygia guttata	30.70	2.00e-35	142.00
IUUC-Tru-118640	Takifugu rubripes	30.61	4.00e-37	149.00
IUUC-Tsy-118869	Tarsius syrichta	35.22	4.00e-28	118.00
IUUC-Tni-120015	Tetraodon nigroviridis	29.67	3.00e-36	145.00
IUUC-Tca-121701	Theobroma cacao	35.36	1.00e-103	369.00
IUUC-Tae-125305	Triticum aestivum	32.80	2.00e-53	203.00
IUUC-Tur-126788	Triticum urartu	39.22	8.00e-37	147.00
IUUC-Tbe-128041	Tupaia belangeri	39.11	4.00e-29	122.00
IUUC-Ttr-128271	Tursiops truncatus	32.24	3.00e-37	149.00
IUUC-Vpa-130674	Vicugna pacos	31.78	1.00e-35	143.00
IUUC-Vvi-131230	Vitis vinifera	71.43	2.00e-21	92.00
IUUC-Xtr-131869	Xenopus tropicalis	30.07	4.00e-37	148.00
IUUC-Xma-134195	Xiphophorus maculatus	28.57	2.00e-37	149.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence