iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/RING	RING	23482858

Classification

Family	E-value	Score	Start	End
E3 activity/RING/RING	1.50e-06	29.5	512	556

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf......kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC++ +      +d  +v+pC H+fh  Clq+w         +  CP+Cr
   Q: 512  CVICMTAIdlrqhtSD-CMVTPCEHFFHSGCLQRW------MDIKMECPTCR 556
           ****998877888766.889***************......**********8 PP

Organism

Arabidopsis thaliana

Protein Sequence
(Fasta)

MKKREHLGLG FFEWQIILWL SIWLAISQQA LGLRPIREKP RSWSDEWLFG RKQEAEVGPF 60
SAWNITGTYR GTWKFLNSLN SSSKFQDFQK ENGNSVVELV AVPTKITGVH YVQGVVVFHD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TATGAAACCT CAACTAACTA ATTTATCAAT TGAACCTTCC TTCGTTTATA ACAGAAAAAG 60
CTAATAAATA AAAATAAAAA TAAAAATCAG AGAGACCAAA AAGAAGTTTC GACTTGTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0012505--C:endomembrane system
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0080001--P:mucilage extrusion from seed coat
GO:0048363--P:mucilage pectin metabolic process
GO:0009827--P:plant-type cell wall modification
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-006241	Arabidopsis lyrata	97.51	0.00e+00	1086.00
IUUC-Acl-008354	Aspergillus clavatus	23.18	8.00e-26	111.00
IUUC-Afl-008715	Aspergillus flavus	28.29	5.00e-24	105.00
IUUC-Afu-008993	Aspergillus fumigatus	22.74	8.00e-26	111.00
IUUC-Ani-009159	Aspergillus nidulans	25.66	1.00e-24	108.00
IUUC-Ang-009736	Aspergillus niger	22.15	2.00e-23	103.00
IUUC-Aor-010205	Aspergillus oryzae	28.29	5.00e-24	105.00
IUUC-Ate-010380	Aspergillus terreus	26.55	1.00e-24	107.00
IUUC-Bgr-012261	Blumeria graminis	26.83	4.00e-15	76.30
IUUC-Bci-013822	Botrytis cinerea	29.17	1.00e-16	81.60
IUUC-Bol-016426	Brassica oleracea	90.44	0.00e+00	1039.00
IUUC-Bra-017704	Brassica rapa	90.09	0.00e+00	1034.00
IUUC-Cre-022642	Chlamydomonas reinhardtii	42.23	3.00e-37	147.00
IUUC-Cgl-026705	Colletotrichum gloeosporioides	26.85	4.00e-22	99.80
IUUC-Cne-027078	Cryptococcus neoformans	33.96	4.00e-15	76.60
IUUC-Cme-027308	Cyanidioschyzon merolae	43.36	6.00e-74	271.00
IUUC-Dse-031227	Dothistroma septosporum	30.04	1.00e-22	101.00
IUUC-Fox-037716	Fusarium oxysporum	26.92	4.00e-18	86.30
IUUC-Fso-038434	Fusarium solani	29.41	2.00e-11	63.50
IUUC-Ggr-039796	Gaeumannomyces graminis	25.91	4.00e-17	82.80
IUUC-Gma-042652	Glycine max	74.51	0.00e+00	847.00
IUUC-Hvu-047407	Hordeum vulgare	71.37	0.00e+00	723.00
IUUC-Kpa-049246	Komagataella pastoris	31.31	7.00e-26	112.00
IUUC-Lpe-050804	Leersia perrieri	69.04	0.00e+00	704.00
IUUC-Lma-052994	Leptosphaeria maculans	27.00	4.00e-20	92.80
IUUC-Mor-057007	Magnaporthe oryzae	26.79	4.00e-20	92.80
IUUC-Mpo-057296	Magnaporthe poae	27.06	2.00e-17	84.00
IUUC-Mvi-060396	Microbotryum violaceum	31.16	4.00e-21	96.30
IUUC-Mac-065030	Musa acuminata	71.27	0.00e+00	748.00
IUUC-Ome-081704	Oryza meridionalis	66.13	0.00e+00	635.00
IUUC-Opu-083443	Oryza punctata	59.75	9.00e-157	545.00
IUUC-Olu-087584	Ostreococcus lucimarinus	44.28	1.00e-62	231.00
IUUC-Pno-095138	Phaeosphaeria nodorum	26.21	2.00e-19	91.70
IUUC-Pgr-103658	Puccinia graminis	28.17	2.00e-16	80.90
IUUC-Ptt-103835	Puccinia triticina	30.13	1.00e-17	84.70
IUUC-Pte-104066	Pyrenophora teres	29.71	3.00e-07	51.20
IUUC-Pyt-104574	Pyrenophora triticirepentis	26.69	2.00e-17	84.00
IUUC-Sja-107916	Schizosaccharomyces japonicus	33.53	2.00e-14	73.20
IUUC-Spo-108066	Schizosaccharomyces pombe	25.71	2.00e-29	123.00
IUUC-Ssl-108517	Sclerotinia sclerotiorum	28.72	2.00e-06	47.00
IUUC-Sit-109719	Setaria italica	73.36	0.00e+00	741.00
IUUC-Sly-111742	Solanum lycopersicum	77.01	0.00e+00	853.00
IUUC-Stu-112706	Solanum tuberosum	77.23	0.00e+00	851.00
IUUC-Sre-114925	Sporisorium reilianum	38.46	6.00e-20	92.40
IUUC-Tca-121160	Theobroma cacao	82.11	0.00e+00	882.00
IUUC-Tre-121878	Trichoderma reesei	26.92	8.00e-20	92.00
IUUC-Tvi-122299	Trichoderma virens	27.70	3.00e-21	96.70
IUUC-Tae-125137	Triticum aestivum	72.97	0.00e+00	759.00
IUUC-Tur-126740	Triticum urartu	75.00	4.00e-85	308.00
IUUC-Tme-126915	Tuber melanosporum	25.20	4.00e-41	162.00
IUUC-Uma-129430	Ustilago maydis	26.54	8.00e-24	105.00
IUUC-Vda-129918	Verticillium dahliae	28.71	2.00e-23	103.00
IUUC-Yli-134449	Yarrowia lipolytica	27.60	6.00e-33	135.00
IUUC-Zma-135016	Zea mays	68.11	4.00e-177	613.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence