iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lma-053096

Ensembl Protein ID

CBX91647

UniProt Accession

E4ZK52; E4ZK52_LEPMJ

Genbank Protein ID

CBX91647.1

Protein Name

Similar to IQ and HECT domain-containing protein

Genbank Nucleotide ID

FP929072

Gene Name

LEMA_P071550.1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
LEMA_P071550.1	CBX91647	CBX91647

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.90e-84	281.0	955	1335

Active Site

Position(s)	Description	Evidence
1303	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp....................ehlklFeflGrll 78
           lk+ + ++f +     E+g+d gGvt+efl+ ++++ + p++ + ++ end++ l+pnp++  +++                    e l+ +eflGr++
   Q: 955  LKEPISITFMDqfgepEAGIDGGGVTKEFLTSVTDRAFMPTNFIDMFVENDQHLLYPNPAAVDEHKealrqaglrenspesrlqisELLQKYEFLGRII 1053
           6777889999999999*************************65556689999999****998655599******************************* PP
   S: 79   gkalqdgrlldlplsksfyklllgk............klsledleevdpelykslkeikenaesdieelgldltfsvseei.........lgetkeeeL 156
           gk+l++g l+d++++++f+++   +            + +l+dl ++d+ely+ l ++k +   d+e+ +l++t++  ++i           ++ ++eL
   Q: 1054 GKCLYEGILVDVNFAPFFLRKWALTggagsapnetgyRPTLNDLRDLDEELYQGLHKLKTY-PGDVEDFSLNFTVT--DNItidhtsnpkKTKAVTKEL 1149
           ********************9844434555555555589**********************.57999988888877..33333566677666777788* PP
   S: 157  kpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketky.....kggytedspaiqwF 249
           kp+G+n+pVtn+N+  Y++ ++ +rl+++   q++af +G+ ++i++++ls+F+++el++li+G+ ++idvedl+++t y      g+   ++p+iq +
   Q: 1150 KPDGANTPVTNQNRLVYISYMARHRLQNQPYLQTTAFLRGLGTMIQPSWLSMFNHSELQTLISGTrTSIDVEDLRRNTVYgglylIGNQGLEHPTIQIL 1248
           ******************************************************************************997777744456789****** PP
   S: 250  wevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirkdasd.drlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           w+v++e+s++er+a L+FvT+++r+Pl Gf +l+pr f ir+++sd +rlPs +TC+n+LkLP Y  +++lkekLly i +++gF+ls
   Q: 1249 WKVMKEMSDDERRAVLKFVTSTPRAPLLGFGTLNPR-FSIRDAGSDqERLPSTSTCVNLLKLPMYRDEKTLKEKLLYSIFSGAGFDLS 1335
           **********************************99.9999988887**************************************985 PP

Organism

Leptosphaeria maculans

Protein Sequence
(Fasta)

MREDRNQIEA CFRLVLKEDL RGDVVSMDVH ERARELEHEH EHEHEHVKKV TASSTDPICG 60
ACGMLIADYS FGWLIHHACL ESLGRQSKLI ASCPGVSDTV VSDTNYRPQR HRPPTVINHA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGAGAAG ATAGGAATCA AATCGAGGCG TGCTTTAGAT TGGTACTAAA GGAAGACCTA 60
AGGGGTGATG TTGTATCGAT GGATGTCCAT GAACGTGCAC GTGAACTCGA ACACGAACAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	34.90	9.00e-83	300.00
IUUC-Aml-001355	Ailuropoda melanoleuca	35.19	7.00e-83	300.00
IUUC-Atr-003017	Amborella trichopoda	34.72	1.00e-82	300.00
IUUC-Apl-003731	Anas platyrhynchos	35.21	9.00e-85	306.00
IUUC-Aca-005248	Anolis carolinensis	35.56	7.00e-86	310.00
IUUC-Aly-005768	Arabidopsis lyrata	38.92	3.00e-79	288.00
IUUC-Ath-007269	Arabidopsis thaliana	39.57	8.00e-84	303.00
IUUC-Ago-007748	Ashbya gossypii	40.60	3.00e-87	315.00
IUUC-Acl-008158	Aspergillus clavatus	49.10	0.00e+00	993.00
IUUC-Afl-008398	Aspergillus flavus	51.10	0.00e+00	1030.00
IUUC-Afu-008937	Aspergillus fumigatus	50.00	0.00e+00	1005.00
IUUC-Ani-009252	Aspergillus nidulans	51.14	0.00e+00	1048.00
IUUC-Ang-009773	Aspergillus niger	49.57	0.00e+00	1006.00
IUUC-Aor-009940	Aspergillus oryzae	51.10	0.00e+00	1029.00
IUUC-Ate-010395	Aspergillus terreus	50.12	0.00e+00	999.00
IUUC-Ame-010769	Astyanax mexicanus	35.77	1.00e-59	223.00
IUUC-Bgr-012269	Blumeria graminis	60.13	2.00e-157	547.00
IUUC-Bta-012841	Bos taurus	35.39	1.00e-84	306.00
IUUC-Bci-013743	Botrytis cinerea	42.53	0.00e+00	857.00
IUUC-Bdi-014502	Brachypodium distachyon	38.17	6.00e-82	297.00
IUUC-Bol-015093	Brassica oleracea	39.15	8.00e-83	300.00
IUUC-Bra-016722	Brassica rapa	39.15	3.00e-83	301.00
IUUC-Cel-018447	Caenorhabditis elegans	33.20	1.00e-57	216.00
IUUC-Cja-019743	Callithrix jacchus	35.09	3.00e-82	298.00
IUUC-Cfa-021031	Canis familiaris	35.19	3.00e-83	301.00
IUUC-Cpo-022401	Cavia porcellus	35.37	2.00e-83	302.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	34.91	3.00e-64	237.00
IUUC-Csa-024107	Chlorocebus sabaeus	34.84	3.00e-82	298.00
IUUC-Cho-024750	Choloepus hoffmanni	41.47	6.00e-75	274.00
IUUC-Cin-025750	Ciona intestinalis	33.20	2.00e-62	232.00
IUUC-Csv-026016	Ciona savignyi	36.99	2.00e-69	256.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	42.57	0.00e+00	823.00
IUUC-Cne-026841	Cryptococcus neoformans	32.60	8.00e-84	303.00
IUUC-Cme-027265	Cyanidioschyzon merolae	41.20	6.00e-84	303.00
IUUC-Dre-028196	Danio rerio	35.78	2.00e-85	309.00
IUUC-Dno-029024	Dasypus novemcinctus	35.54	3.00e-84	305.00
IUUC-Dor-030938	Dipodomys ordii	37.47	2.00e-67	249.00
IUUC-Dse-031416	Dothistroma septosporum	44.86	0.00e+00	866.00
IUUC-Dme-031946	Drosophila melanogaster	37.88	1.00e-76	280.00
IUUC-Ete-033041	Echinops telfairi	34.20	2.00e-45	176.00
IUUC-Eca-033828	Equus caballus	35.39	1.00e-83	303.00
IUUC-Eeu-035201	Erinaceus europaeus	34.77	5.00e-47	181.00
IUUC-Fca-035907	Felis catus	35.25	4.00e-83	301.00
IUUC-Fal-037389	Ficedula albicollis	35.04	4.00e-84	305.00
IUUC-Fox-037788	Fusarium oxysporum	45.96	0.00e+00	669.00
IUUC-Fso-038088	Fusarium solani	42.84	0.00e+00	626.00
IUUC-Gmo-039412	Gadus morhua	34.09	3.00e-66	245.00
IUUC-Ggr-039941	Gaeumannomyces graminis	41.04	0.00e+00	738.00
IUUC-Gga-040310	Gallus gallus	35.04	2.00e-84	305.00
IUUC-Gac-042088	Gasterosteus aculeatus	34.70	3.00e-68	252.00
IUUC-Gma-042819	Glycine max	38.84	5.00e-71	261.00
IUUC-Ggo-045031	Gorilla gorilla	35.02	1.00e-82	300.00
IUUC-Hsa-045880	Homo sapiens	35.02	9.00e-83	300.00
IUUC-Hvu-047102	Hordeum vulgare	34.55	3.00e-82	298.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	37.24	1.00e-66	245.00
IUUC-Kpa-049307	Komagataella pastoris	31.94	6.00e-81	294.00
IUUC-Lch-050664	Latimeria chalumnae	35.46	8.00e-70	257.00
IUUC-Lpe-050755	Leersia perrieri	38.11	3.00e-80	291.00
IUUC-Loc-052218	Lepisosteus oculatus	35.84	1.00e-83	302.00
IUUC-Laf-053902	Loxodonta africana	33.05	2.00e-70	259.00
IUUC-Mcc-055127	Macaca mulatta	35.02	1.00e-82	299.00
IUUC-Meu-056527	Macropus eugenii	39.21	1.00e-55	209.00
IUUC-Mor-057021	Magnaporthe oryzae	40.71	0.00e+00	754.00
IUUC-Mpo-057570	Magnaporthe poae	45.18	0.00e+00	685.00
IUUC-Mtr-058154	Medicago truncatula	39.70	2.00e-74	272.00
IUUC-Mla-059124	Melampsora laricipopulina	41.94	2.00e-95	341.00
IUUC-Mga-059581	Meleagris gallopavo	35.04	2.00e-84	305.00
IUUC-Mvi-060445	Microbotryum violaceum	37.97	3.00e-111	395.00
IUUC-Mmr-061360	Microcebus murinus	35.43	2.00e-83	301.00
IUUC-Mdo-062194	Monodelphis domestica	35.56	2.00e-84	305.00
IUUC-Mmu-064189	Mus musculus	35.08	7.00e-83	300.00
IUUC-Mac-065275	Musa acuminata	38.12	5.00e-81	293.00
IUUC-Mpu-066439	Mustela putorius furo	34.96	2.00e-83	302.00
IUUC-Mlu-068228	Myotis lucifugus	35.39	9.00e-84	303.00
IUUC-Nfi-068280	Neosartorya fischeri	50.08	0.00e+00	1008.00
IUUC-Ncr-068869	Neurospora crassa	40.94	0.00e+00	739.00
IUUC-Nle-069687	Nomascus leucogenys	34.55	3.00e-82	298.00
IUUC-Opr-070554	Ochotona princeps	33.05	2.00e-69	256.00
IUUC-Ont-071836	Oreochromis niloticus	35.60	6.00e-85	307.00
IUUC-Oan-072800	Ornithorhynchus anatinus	35.21	2.00e-84	306.00
IUUC-Ocu-074587	Oryctolagus cuniculus	35.37	8.00e-84	303.00
IUUC-Oba-075213	Oryza barthii	37.60	1.00e-82	300.00
IUUC-Obr-076320	Oryza brachyantha	38.14	4.00e-84	305.00
IUUC-Ogl-077093	Oryza glaberrima	38.02	8.00e-84	303.00
IUUC-Ogu-078947	Oryza glumaepatula	38.97	3.00e-81	295.00
IUUC-Oin-080058	Oryza indica	38.17	9.00e-84	303.00
IUUC-Olo-080742	Oryza longistaminata	38.02	2.00e-83	302.00
IUUC-Ome-081741	Oryza meridionalis	37.83	1.00e-77	283.00
IUUC-Oni-082385	Oryza nivara	38.97	3.00e-81	295.00
IUUC-Opu-083529	Oryza punctata	38.22	5.00e-84	304.00
IUUC-Oru-085128	Oryza rufipogon	36.70	6.00e-74	271.00
IUUC-Osa-085557	Oryza sativa	38.17	2.00e-83	301.00
IUUC-Ola-087209	Oryzias latipes	35.78	2.00e-85	309.00
IUUC-Olu-087699	Ostreococcus lucimarinus	38.89	2.00e-69	254.00
IUUC-Oga-088776	Otolemur garnettii	35.37	3.00e-83	301.00
IUUC-Oar-089441	Ovis aries	35.45	1.00e-84	306.00
IUUC-Ptr-091273	Pan troglodytes	35.02	9.00e-83	300.00
IUUC-Pan-091981	Papio anubis	35.02	9.00e-83	300.00
IUUC-Psi-093251	Pelodiscus sinensis	35.53	3.00e-59	222.00
IUUC-Pma-094738	Petromyzon marinus	32.41	6.00e-84	304.00
IUUC-Pno-095132	Phaeosphaeria nodorum	78.58	0.00e+00	1335.00
IUUC-Ppa-095544	Physcomitrella patens	38.66	5.00e-82	298.00
IUUC-Pfo-097511	Poecilia formosa	36.13	1.00e-86	313.00
IUUC-Pab-098570	Pongo abelii	33.73	9.00e-73	267.00
IUUC-Pop-098928	Populus trichocarpa	38.63	3.00e-72	265.00
IUUC-Pca-100987	Procavia capensis	41.04	3.00e-77	281.00
IUUC-Ppe-101281	Prunus persica	39.36	2.00e-83	302.00
IUUC-Pva-102887	Pteropus vampyrus	36.49	4.00e-71	261.00
IUUC-Pgr-103513	Puccinia graminis	35.68	5.00e-106	377.00
IUUC-Ptt-103967	Puccinia triticina	34.43	1.00e-93	336.00
IUUC-Pte-104105	Pyrenophora teres	77.97	0.00e+00	1783.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	78.08	0.00e+00	1769.00
IUUC-Rno-106028	Rattus norvegicus	32.58	9.00e-53	200.00
IUUC-Sce-106446	Saccharomyces cerevisiae	41.34	4.00e-84	304.00
IUUC-Sha-107108	Sarcophilus harrisii	33.39	6.00e-73	267.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	33.57	8.00e-94	337.00
IUUC-Spo-108097	Schizosaccharomyces pombe	32.43	2.00e-97	348.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	42.29	0.00e+00	844.00
IUUC-Smo-109537	Selaginella moellendorffii	38.53	2.00e-80	292.00
IUUC-Sit-110457	Setaria italica	39.83	1.00e-74	273.00
IUUC-Sly-111362	Solanum lycopersicum	39.48	1.00e-74	273.00
IUUC-Sar-113687	Sorex araneus	32.05	7.00e-39	154.00
IUUC-Sbi-114433	Sorghum bicolor	38.59	1.00e-82	299.00
IUUC-Sre-115038	Sporisorium reilianum	46.71	9.00e-102	363.00
IUUC-Ssc-116103	Sus scrofa	36.29	6.00e-70	257.00
IUUC-Tgu-116729	Taeniopygia guttata	35.04	7.00e-84	304.00
IUUC-Tru-118068	Takifugu rubripes	35.39	4.00e-83	301.00
IUUC-Tsy-118942	Tarsius syrichta	44.09	6.00e-59	221.00
IUUC-Tni-120732	Tetraodon nigroviridis	34.68	2.00e-77	282.00
IUUC-Tca-121770	Theobroma cacao	40.21	5.00e-86	311.00
IUUC-Tre-121892	Trichoderma reesei	40.11	0.00e+00	727.00
IUUC-Tvi-122354	Trichoderma virens	40.73	0.00e+00	764.00
IUUC-Tae-125466	Triticum aestivum	39.27	1.00e-80	293.00
IUUC-Tur-126086	Triticum urartu	34.90	7.00e-83	300.00
IUUC-Tme-127102	Tuber melanosporum	47.71	0.00e+00	694.00
IUUC-Tbe-127351	Tupaia belangeri	35.47	6.00e-61	227.00
IUUC-Ttr-129061	Tursiops truncatus	40.45	8.00e-77	280.00
IUUC-Uma-129343	Ustilago maydis	37.76	3.00e-113	401.00
IUUC-Vda-129748	Verticillium dahliae	45.11	0.00e+00	663.00
IUUC-Vvi-131234	Vitis vinifera	40.22	5.00e-74	271.00
IUUC-Xtr-132094	Xenopus tropicalis	35.21	1.00e-82	300.00
IUUC-Xma-133923	Xiphophorus maculatus	36.13	1.00e-86	313.00
IUUC-Yli-134496	Yarrowia lipolytica	39.89	3.00e-96	344.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence