iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008943

Ensembl Protein ID

CADAFUAP00005203

UniProt Accession

Q4WY40; Q4WY40_ASPFU

Genbank Protein ID

EAL92413.1

Protein Name

Ubiquitin C-terminal hydrolase, putative

Genbank Nucleotide ID

AAHF01000002

Gene Name

AFUA_3G11700

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00005203	CADAFUAT00005203	CADAFUAP00005203

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.40e-50	169.0	47	641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..........kkkeklneenp....................kepkgellkslqklfeelw.. 61
           +Gl+N  N C++NSvLQ+L+ + +lr +l +                                         + ++g+++++l++++  l   
   Q: 47   VGLSNPANDCFINSVLQALAGLGDLRVYLIRelhrreldgpD---------VynslpeanetprgmtperirELQQGTITRALKEMLDRLNer 130
           6******************************75555554441.........24455555556666666666666778*************977 PP
   S: 62   kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkk................eknkpkeeeeeedkselsde......... 129
              kk ++ r++++al+ + +   + +qqDaqEfl+++ ++l +e +                                    +         
   Q: 131  PIYKKTITNRAFIQALEYAFRTRISRNQQDAQEFLQIVAERLCDEYHAglkarqraqglpatlpG------------------Sggeesvqss 205
           7778999**********99999889******************9995555555544444333330..................1444444455 PP
   S: 130  .......................aeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesftkee 198
                                    ++k k+ ++     F+gq++sqi c+ c+ ++   + +f+ l+l+vp+k++t   +l++c++   k+e
   Q: 206  avekgsaeievriddgtemglpaIIDNKLKEIDNAYGFPFEGQMESQIECQFCHYQYkPNKTSFVNLTLQVPQKSST---TLSSCFDGLLKTE 295
           66666777778888999999999889999999************************989999*************99...************* PP
   S: 199  elegenkyycekck......................................................kkqeaekklklkklPevLilhLkRf 237
            +++   + c++c+                                                       k++  + ++++ +P+++ +hL+R 
   Q: 296  YIDD---FRCDRCRlqhaldakmvelsrshstrdrerleqeiqltrhaiatdpenppegvslppsdlaPKRKIARHMRITIFPKIIAIHLSRS 385
           **97...*******9*********999999999999999999999999999999999999999999998888********************* PP
   S: 238  sfseeqksrekinkkvefpleLdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn............................. 301
            f++  +s++k+  kv+fp++L l   +++        k ++L+a+v+H+Gs++sGHY ++ +n                             
   Q: 386  IFDR--SSSTKNAAKVSFPERLPLGGILSQ--------KWFKLLAIVCHKGSHNSGHYESFRRNnlyppfstpdtfssyaqsratsvnpstap 468
           9988..5889***************88888........78***************************************************** PP
   S: 302  ............................................................................................. 301
                                                                                                        
   Q: 469  sprlaargvaepepspislssstslpslsgsslpsparsqtvsvrdssqpasqlnappspsarpttsssrvsfqsirtkssgskqnlsppgse 561
           ********************************************************************************************* PP
   S: 302  ..............................................ekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
                                                         ++++W++++D+k++e+k ++vl ++ ++ Y+lfY+
   Q: 562  tpspasdsgawsksgsrpsfmserttsktppeapalsssrlrrrkkTNDRWWRISDEKIKECKTSDVLGMQ-KEVYLLFYE 641
           ***************************99999999999999987655666*******************65.9*******8 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MQEKSTTIAA YAAGASLAAV ALFYVFGPNY TIDGDDSNDS NRKKSIVGLS NPANDCFINS 60
VLQALAGLGD LRVYLIRELH RRELDGPDVY NSLPEANETP RGMTPERIRE LQQGTITRAL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGGAAA AGTCGACAAC CATCGCCGCA TACGCAGCCG GAGCATCCCT GGCGGCCGTG 60
GCCCTCTTCT ACGTCTTCGG GCCAAATTAC ACAATCGACG GCGATGACTC GAACGACAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

afm:AFUA_3G11700

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007955	Ashbya gossypii	26.39	5.00e-22	97.80
IUUC-Acl-008228	Aspergillus clavatus	82.59	0.00e+00	927.00
IUUC-Afl-008530	Aspergillus flavus	80.75	0.00e+00	772.00
IUUC-Ang-009829	Aspergillus niger	79.00	0.00e+00	763.00
IUUC-Aor-009934	Aspergillus oryzae	81.64	0.00e+00	739.00
IUUC-Ate-010439	Aspergillus terreus	79.87	0.00e+00	773.00
IUUC-Bgr-012072	Blumeria graminis	47.47	3.00e-96	343.00
IUUC-Bci-013641	Botrytis cinerea	52.21	3.00e-129	453.00
IUUC-Cgl-026463	Colletotrichum gloeosporioides	51.69	3.00e-120	423.00
IUUC-Dse-031517	Dothistroma septosporum	49.37	1.00e-115	409.00
IUUC-Fox-037837	Fusarium oxysporum	45.78	7.00e-143	499.00
IUUC-Ggr-039945	Gaeumannomyces graminis	59.70	8.00e-72	263.00
IUUC-Lma-053197	Leptosphaeria maculans	53.01	8.00e-105	372.00
IUUC-Mor-057061	Magnaporthe oryzae	51.01	7.00e-125	439.00
IUUC-Mpo-057549	Magnaporthe poae	57.43	2.00e-69	255.00
IUUC-Nfi-068557	Neosartorya fischeri	96.45	0.00e+00	1133.00
IUUC-Ncr-068961	Neurospora crassa	51.15	1.00e-112	399.00
IUUC-Oin-080096	Oryza indica	27.57	3.00e-09	54.70
IUUC-Pno-094802	Phaeosphaeria nodorum	58.08	2.00e-139	486.00
IUUC-Pte-104416	Pyrenophora teres	56.96	5.00e-137	479.00
IUUC-Pyt-104503	Pyrenophora triticirepentis	57.14	4.00e-139	486.00
IUUC-Tre-121937	Trichoderma reesei	49.02	1.00e-115	408.00
IUUC-Tvi-122428	Trichoderma virens	49.33	5.00e-116	409.00
IUUC-Tme-126993	Tuber melanosporum	47.89	7.00e-100	356.00
IUUC-Vda-129757	Verticillium dahliae	48.12	2.00e-117	414.00
IUUC-Yli-134426	Yarrowia lipolytica	31.36	8.00e-39	153.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence