iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020845

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03004190

Gene Name

RABGEF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000010773.3	ENSCAFT00000017144.3	ENSCAFP00000015865.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/MIU	5.40e-08	32.9	255	278

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/MIU

   S: 1    rqkQprtDlELAqqLQqEeyqqfa 24
           rqkQ+++D+ELA++LQ+Ee+++fa
   Q: 255  RQKQIQEDWELAERLQREEEEAFA 278
           8********************986 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MVVVTGREPD SRRPDGAMSS SDAEDDFLEP ATPTATQAGH ALPLLPQEFP EVVPLNIGGA 60
HFTTRLSTLR RYEDTMLAAM FSGRHYIPTD AEGRYFIDRD GTHFGDVLNF LRSGDLPPRE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNGTGCCC GGGCCGCCGC CGCCGCCGCC 60
GCCGCCCGCC GTCGCCGCCG CCCGCAGCCG CGCCCACTGC CCGGAGCCAG AGGGATGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR003131--T1-type_BTB
IPR003123--VPS9

PROSITE

PS51205--VPS9

Pfam

PF02214--BTB_2
PF02204--VPS9

SMART

SM00225--BTB
SM00167--VPS9

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0005730--C:nucleolus
GO:0017112--F:Rab guanyl-nucleotide exchange factor activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0050728--P:negative regulation of inflammatory response
GO:1900165--P:negative regulation of interleukin-6 secretion
GO:1900235--P:negative regulation of Kit signaling pathway
GO:0002686--P:negative regulation of leukocyte migration
GO:0043305--P:negative regulation of mast cell degranulation
GO:0001933--P:negative regulation of protein phosphorylation
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0048261--P:negative regulation of receptor-mediated endocytosis
GO:0051260--P:protein homooligomerization
GO:0006612--P:protein targeting to membrane
GO:0060368--P:regulation of Fc receptor mediated stimulatory signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000198	Aegilops tauschii	32.26	2.00e-20	93.60
IUUC-Aml-001771	Ailuropoda melanoleuca	89.86	0.00e+00	769.00
IUUC-Atr-003154	Amborella trichopoda	36.52	7.00e-23	101.00
IUUC-Apl-004018	Anas platyrhynchos	91.11	0.00e+00	771.00
IUUC-Aca-005041	Anolis carolinensis	39.22	1.00e-25	109.00
IUUC-Aly-006138	Arabidopsis lyrata	35.45	7.00e-25	108.00
IUUC-Ath-006747	Arabidopsis thaliana	34.92	1.00e-24	107.00
IUUC-Ago-007776	Ashbya gossypii	29.34	5.00e-23	102.00
IUUC-Acl-008235	Aspergillus clavatus	30.74	6.00e-29	122.00
IUUC-Afl-008570	Aspergillus flavus	31.88	2.00e-31	131.00
IUUC-Afu-008815	Aspergillus fumigatus	30.88	2.00e-29	124.00
IUUC-Ani-009381	Aspergillus nidulans	30.39	1.00e-29	125.00
IUUC-Ang-009615	Aspergillus niger	28.74	1.00e-31	131.00
IUUC-Aor-010195	Aspergillus oryzae	32.21	5.00e-32	132.00
IUUC-Ate-010514	Aspergillus terreus	31.10	7.00e-30	125.00
IUUC-Ame-011365	Astyanax mexicanus	64.64	1.00e-173	602.00
IUUC-Bgr-012102	Blumeria graminis	28.53	6.00e-30	125.00
IUUC-Bta-013124	Bos taurus	98.04	0.00e+00	817.00
IUUC-Bci-013943	Botrytis cinerea	30.50	2.00e-30	127.00
IUUC-Bdi-014539	Brachypodium distachyon	34.70	3.00e-26	112.00
IUUC-Bol-016580	Brassica oleracea	35.14	4.00e-30	125.00
IUUC-Bra-017843	Brassica rapa	34.68	7.00e-30	125.00
IUUC-Cel-018199	Caenorhabditis elegans	33.70	1.00e-49	191.00
IUUC-Cja-019941	Callithrix jacchus	96.52	0.00e+00	803.00
IUUC-Cpo-022037	Cavia porcellus	95.87	0.00e+00	796.00
IUUC-Cre-022696	Chlamydomonas reinhardtii	31.98	2.00e-20	93.60
IUUC-Csa-023495	Chlorocebus sabaeus	96.30	0.00e+00	806.00
IUUC-Cho-025076	Choloepus hoffmanni	85.00	0.00e+00	670.00
IUUC-Cin-025400	Ciona intestinalis	43.31	1.00e-99	356.00
IUUC-Csv-025941	Ciona savignyi	38.29	8.00e-88	317.00
IUUC-Cgl-026725	Colletotrichum gloeosporioides	29.08	1.00e-27	118.00
IUUC-Cne-027057	Cryptococcus neoformans	33.46	2.00e-34	140.00
IUUC-Dre-028484	Danio rerio	69.46	5.00e-174	603.00
IUUC-Dno-028906	Dasypus novemcinctus	97.61	0.00e+00	808.00
IUUC-Dor-030124	Dipodomys ordii	85.22	0.00e+00	678.00
IUUC-Dse-031437	Dothistroma septosporum	28.32	2.00e-26	114.00
IUUC-Dme-031696	Drosophila melanogaster	33.26	6.00e-61	228.00
IUUC-Ete-032573	Echinops telfairi	92.80	0.00e+00	718.00
IUUC-Eca-033711	Equus caballus	98.48	0.00e+00	822.00
IUUC-Eeu-034459	Erinaceus europaeus	73.43	2.00e-78	286.00
IUUC-Fca-035447	Felis catus	97.61	0.00e+00	835.00
IUUC-Fal-036605	Ficedula albicollis	87.69	0.00e+00	712.00
IUUC-Fox-037967	Fusarium oxysporum	26.35	8.00e-18	85.90
IUUC-Fso-038110	Fusarium solani	29.68	1.00e-29	125.00
IUUC-Gmo-038785	Gadus morhua	64.51	3.00e-174	604.00
IUUC-Ggr-039760	Gaeumannomyces graminis	30.32	6.00e-27	116.00
IUUC-Gga-040584	Gallus gallus	91.96	0.00e+00	783.00
IUUC-Gac-042469	Gasterosteus aculeatus	63.81	3.00e-151	528.00
IUUC-Gma-044237	Glycine max	37.43	4.00e-26	112.00
IUUC-Ggo-044498	Gorilla gorilla	82.61	0.00e+00	664.00
IUUC-Hsa-046625	Homo sapiens	96.74	0.00e+00	806.00
IUUC-Hvu-047155	Hordeum vulgare	38.20	2.00e-26	113.00
IUUC-Itr-048753	Ictidomys tridecemlineatus	96.09	0.00e+00	799.00
IUUC-Kpa-049160	Komagataella pastoris	29.05	1.00e-24	108.00
IUUC-Lch-050529	Latimeria chalumnae	77.34	0.00e+00	780.00
IUUC-Lpe-051024	Leersia perrieri	35.16	9.00e-29	121.00
IUUC-Loc-052644	Lepisosteus oculatus	68.51	4.00e-172	597.00
IUUC-Lma-053102	Leptosphaeria maculans	31.75	8.00e-28	119.00
IUUC-Laf-054337	Loxodonta africana	94.78	0.00e+00	793.00
IUUC-Mcc-055659	Macaca mulatta	96.08	3.00e-155	541.00
IUUC-Meu-056084	Macropus eugenii	76.47	7.00e-94	337.00
IUUC-Mor-057255	Magnaporthe oryzae	29.60	2.00e-27	117.00
IUUC-Mpo-057454	Magnaporthe poae	30.32	1.00e-28	121.00
IUUC-Mtr-058098	Medicago truncatula	32.20	1.00e-30	127.00
IUUC-Mla-059068	Melampsora laricipopulina	31.20	3.00e-31	129.00
IUUC-Mga-059624	Meleagris gallopavo	77.29	0.00e+00	764.00
IUUC-Mvi-060282	Microbotryum violaceum	48.25	6.00e-21	96.70
IUUC-Mmr-061142	Microcebus murinus	97.17	0.00e+00	815.00
IUUC-Mdo-062289	Monodelphis domestica	92.83	0.00e+00	826.00
IUUC-Mmu-063961	Mus musculus	96.30	0.00e+00	801.00
IUUC-Mac-065188	Musa acuminata	33.73	3.00e-23	102.00
IUUC-Mpu-066291	Mustela putorius furo	98.04	0.00e+00	824.00
IUUC-Mlu-067431	Myotis lucifugus	93.26	0.00e+00	779.00
IUUC-Nfi-068422	Neosartorya fischeri	30.77	2.00e-30	127.00
IUUC-Ncr-068843	Neurospora crassa	28.85	1.00e-29	125.00
IUUC-Nle-069079	Nomascus leucogenys	96.52	0.00e+00	803.00
IUUC-Opr-070790	Ochotona princeps	94.44	9.00e-57	214.00
IUUC-Ont-071789	Oreochromis niloticus	66.89	3.00e-157	548.00
IUUC-Oan-072946	Ornithorhynchus anatinus	89.59	0.00e+00	746.00
IUUC-Ocu-073816	Oryctolagus cuniculus	97.61	0.00e+00	814.00
IUUC-Oba-075738	Oryza barthii	33.71	5.00e-18	85.50
IUUC-Obr-076355	Oryza brachyantha	38.33	2.00e-27	116.00
IUUC-Ogl-077592	Oryza glaberrima	28.74	1.00e-27	116.00
IUUC-Ogu-078197	Oryza glumaepatula	28.74	3.00e-27	115.00
IUUC-Oin-080047	Oryza indica	38.20	3.00e-26	112.00
IUUC-Olo-080317	Oryza longistaminata	28.74	3.00e-27	115.00
IUUC-Ome-081589	Oryza meridionalis	36.72	4.00e-26	113.00
IUUC-Oni-082700	Oryza nivara	33.71	4.00e-18	85.90
IUUC-Opu-083923	Oryza punctata	34.36	2.00e-21	96.30
IUUC-Oru-084318	Oryza rufipogon	33.71	4.00e-18	85.90
IUUC-Ola-086730	Oryzias latipes	54.80	9.00e-133	466.00
IUUC-Olu-087719	Ostreococcus lucimarinus	34.46	6.00e-24	105.00
IUUC-Oga-088992	Otolemur garnettii	84.14	0.00e+00	818.00
IUUC-Oar-089789	Ovis aries	97.83	0.00e+00	818.00
IUUC-Ptr-091636	Pan troglodytes	96.74	0.00e+00	804.00
IUUC-Pan-092911	Papio anubis	96.09	0.00e+00	800.00
IUUC-Psi-093194	Pelodiscus sinensis	78.64	0.00e+00	776.00
IUUC-Pma-094212	Petromyzon marinus	45.92	5.00e-94	338.00
IUUC-Pno-094831	Phaeosphaeria nodorum	29.89	6.00e-28	119.00
IUUC-Ppa-095705	Physcomitrella patens	31.50	3.00e-29	123.00
IUUC-Pfo-096694	Poecilia formosa	63.47	4.00e-160	557.00
IUUC-Pab-097706	Pongo abelii	96.52	0.00e+00	803.00
IUUC-Pop-099891	Populus trichocarpa	33.21	3.00e-26	113.00
IUUC-Pca-100879	Procavia capensis	92.99	5.00e-90	324.00
IUUC-Ppe-101334	Prunus persica	31.60	1.00e-26	114.00
IUUC-Pva-103225	Pteropus vampyrus	81.47	0.00e+00	648.00
IUUC-Pgr-103564	Puccinia graminis	30.38	3.00e-31	130.00
IUUC-Ptt-103802	Puccinia triticina	29.53	8.00e-26	111.00
IUUC-Pte-104345	Pyrenophora teres	30.43	4.00e-28	120.00
IUUC-Pyt-104716	Pyrenophora triticirepentis	30.60	8.00e-29	122.00
IUUC-Rno-106101	Rattus norvegicus	96.09	0.00e+00	801.00
IUUC-Sce-106460	Saccharomyces cerevisiae	29.68	3.00e-25	109.00
IUUC-Sha-106919	Sarcophilus harrisii	79.59	0.00e+00	778.00
IUUC-Sja-107880	Schizosaccharomyces japonicus	32.75	3.00e-31	129.00
IUUC-Spo-108087	Schizosaccharomyces pombe	30.23	2.00e-27	117.00
IUUC-Ssl-108614	Sclerotinia sclerotiorum	25.78	1.00e-07	52.40
IUUC-Smo-109411	Selaginella moellendorffii	36.67	7.00e-29	121.00
IUUC-Sit-110678	Setaria italica	37.64	2.00e-26	113.00
IUUC-Sly-111526	Solanum lycopersicum	37.50	1.00e-25	110.00
IUUC-Stu-112494	Solanum tuberosum	36.93	3.00e-26	112.00
IUUC-Sar-112929	Sorex araneus	98.55	2.00e-163	569.00
IUUC-Sbi-114242	Sorghum bicolor	33.86	2.00e-28	120.00
IUUC-Sre-115224	Sporisorium reilianum	30.96	8.00e-30	126.00
IUUC-Ssc-115239	Sus scrofa	98.48	0.00e+00	825.00
IUUC-Tgu-117499	Taeniopygia guttata	89.35	0.00e+00	751.00
IUUC-Tru-118450	Takifugu rubripes	58.80	1.00e-153	536.00
IUUC-Tsy-119462	Tarsius syrichta	96.96	0.00e+00	815.00
IUUC-Tni-120855	Tetraodon nigroviridis	59.03	3.00e-156	545.00
IUUC-Tca-121213	Theobroma cacao	33.03	3.00e-25	109.00
IUUC-Tre-122186	Trichoderma reesei	28.85	1.00e-28	121.00
IUUC-Tvi-122541	Trichoderma virens	27.68	6.00e-29	122.00
IUUC-Tae-123631	Triticum aestivum	35.18	1.00e-27	117.00
IUUC-Tur-126572	Triticum urartu	39.33	2.00e-26	114.00
IUUC-Tme-127023	Tuber melanosporum	32.93	7.00e-32	132.00
IUUC-Tbe-127453	Tupaia belangeri	97.93	0.00e+00	777.00
IUUC-Ttr-128526	Tursiops truncatus	97.61	0.00e+00	814.00
IUUC-Uma-129660	Ustilago maydis	31.91	3.00e-30	127.00
IUUC-Vda-129737	Verticillium dahliae	28.91	8.00e-25	108.00
IUUC-Vpa-130505	Vicugna pacos	91.45	0.00e+00	716.00
IUUC-Vvi-131088	Vitis vinifera	37.08	4.00e-24	105.00
IUUC-Xtr-132799	Xenopus tropicalis	74.13	0.00e+00	669.00
IUUC-Xma-133345	Xiphophorus maculatus	64.11	8.00e-156	543.00
IUUC-Yli-134416	Yarrowia lipolytica	32.48	3.00e-32	132.00
IUUC-Zma-134750	Zea mays	38.20	4.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence