iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092605

Ensembl Protein ID

ENSPANP00000009643.1

UniProt Accession

A0A096NAD5; A0A096NAD5_PAPAN

Genbank Protein ID

ENSPANP00000009643

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01061917

Gene Name

TRIM22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000002935.1	ENSPANT00000008922.1	ENSPANP00000009643.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.50e-09	38.3	15	60
E3 activity/RING/U-box	1.60e-07	31.4	9	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iCle + + pl+l+CgH f++ C+  k++ +   s++e +CP+C+
   Q: 15   CPICLELLTE-PLSLDCGHSFCQACItAKIKESVTISRGESSCPVCQ 60
           ********99.***************7555888899**********7 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggk......tcPvtrqplteedlvPnltlrrliq 66
           + +e  CpI lel ++P  l +G+++ +++I   ++++ +      +cPv+++++++ +l Pn  l ++++
   Q: 9    IEKEVTCPICLELLTEPLSLDCGHSFCQACITAKIKESVTisrgesSCPVCQSRFQPGKLRPNRHLANIVE 79
           567899***************************9966666666666******************9988776 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MDFSVKVDIE KEVTCPICLE LLTEPLSLDC GHSFCQACIT AKIKESVTIS RGESSCPVCQ 60
SRFQPGKLRP NRHLANIVER VKEVKMSPQE GQKRDICEHH GKLQIFCKED GKTGFHRVSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATTTCT CAGTAAAGGT AGACATAGAG AAGGAGGTGA CCTGCCCCAT CTGCCTGGAG 60
CTCCTAACAG AACCTCTGAG CCTAGATTGT GGCCACAGCT TCTGCCAAGC CTGCATCACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0070206--P:protein trimerization
GO:0032880--P:regulation of protein localization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002371	Ailuropoda melanoleuca	62.28	2.00e-178	618.00
IUUC-Acl-008013	Aspergillus clavatus	58.82	2.00e-06	48.10
IUUC-Ani-009293	Aspergillus nidulans	60.61	5.00e-06	47.00
IUUC-Cfa-021080	Canis familiaris	61.65	3.00e-176	611.00
IUUC-Cre-022597	Chlamydomonas reinhardtii	33.75	1.00e-09	57.40
IUUC-Csa-023785	Chlorocebus sabaeus	84.94	0.00e+00	822.00
IUUC-Eca-034336	Equus caballus	61.88	2.00e-169	589.00
IUUC-Ggo-044550	Gorilla gorilla	81.33	0.00e+00	753.00
IUUC-Hsa-046363	Homo sapiens	81.93	0.00e+00	793.00
IUUC-Laf-053647	Loxodonta africana	59.76	2.00e-159	555.00
IUUC-Mcc-054743	Macaca mulatta	88.96	0.00e+00	864.00
IUUC-Mpu-066674	Mustela putorius furo	61.04	3.00e-177	614.00
IUUC-Nle-068980	Nomascus leucogenys	82.33	0.00e+00	793.00
IUUC-Ptr-091300	Pan troglodytes	81.33	0.00e+00	782.00
IUUC-Pab-098535	Pongo abelii	82.13	0.00e+00	793.00
IUUC-Tsy-119330	Tarsius syrichta	70.82	0.00e+00	666.00
IUUC-Tur-126362	Triticum urartu	37.88	3.00e-07	49.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence