iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-013531

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02045269

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000002328.5	ENSBTAT00000003003.5	ENSBTAP00000003003.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.20e-14	54.4	633	698

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede.....k.....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++     +     +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 633  AVCLVCGEAGKEDtveeeEgkfnlMLMECSICNEIIHPGCLKIKesegvVNDELPNC--WECPKCNHA 698
           79*********9977765156789*********************************..*******85 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MEAEKDSGRR LRPIDRQRYD ENEDLSDVEE IVSARGFSLE EKLRSQLYQG DFVHAMEGKD 60
FNYEYVQREA LRVPLVFREK DGLGIKMPDP DFTVRDVKLL VGSRRLVDVM DVNTQKGTEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCAG AGAAAGACTC TGGAAGAAGA TTGGTGTGTA GCTTTTTTTT TTTTTTCCAA 60
ATCTGTATCT GGTTTATGAT AGATCTATTT TTTTTTGGTC GTTGTTTCTT GCTGCCTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0031519--C:PcG protein complex
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0008270--F:zinc ion binding
GO:0048596--P:embryonic camera-type eye morphogenesis
GO:0021592--P:fourth ventricle development
GO:0035518--P:histone H2A monoubiquitination
GO:0070544--P:histone H3-K36 demethylation
GO:0021993--P:initiation of neural tube closure
GO:0021670--P:lateral ventricle development
GO:0030901--P:midbrain development
GO:0021555--P:midbrain-hindbrain boundary morphogenesis
GO:2000178--P:negative regulation of neural precursor cell proliferation
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030307--P:positive regulation of cell growth
GO:1902459--P:positive regulation of stem cell population maintenance
GO:0007283--P:spermatogenesis
GO:0021678--P:third ventricle development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	97.26	0.00e+00	2308.00
IUUC-Apl-003787	Anas platyrhynchos	84.13	0.00e+00	1926.00
IUUC-Aca-004247	Anolis carolinensis	78.61	0.00e+00	1825.00
IUUC-Acl-008303	Aspergillus clavatus	45.25	1.00e-63	238.00
IUUC-Afl-008579	Aspergillus flavus	42.55	2.00e-23	104.00
IUUC-Afu-008903	Aspergillus fumigatus	45.25	1.00e-63	238.00
IUUC-Ani-009279	Aspergillus nidulans	46.83	2.00e-63	238.00
IUUC-Ang-009645	Aspergillus niger	45.08	2.00e-60	228.00
IUUC-Aor-010233	Aspergillus oryzae	46.01	2.00e-63	237.00
IUUC-Ate-010345	Aspergillus terreus	46.01	5.00e-65	243.00
IUUC-Ame-011463	Astyanax mexicanus	75.21	2.00e-172	600.00
IUUC-Cel-018303	Caenorhabditis elegans	44.86	6.00e-83	302.00
IUUC-Cja-018876	Callithrix jacchus	92.46	0.00e+00	2147.00
IUUC-Cfa-020857	Canis familiaris	97.25	0.00e+00	2350.00
IUUC-Cpo-021967	Cavia porcellus	93.89	0.00e+00	2162.00
IUUC-Csa-023210	Chlorocebus sabaeus	96.37	0.00e+00	2264.00
IUUC-Cin-025140	Ciona intestinalis	60.43	5.00e-106	379.00
IUUC-Csv-025861	Ciona savignyi	56.79	1.00e-115	410.00
IUUC-Cne-026797	Cryptococcus neoformans	38.25	4.00e-57	216.00
IUUC-Cme-027118	Cyanidioschyzon merolae	36.36	6.00e-49	189.00
IUUC-Dre-028272	Danio rerio	64.52	0.00e+00	1540.00
IUUC-Dno-030034	Dasypus novemcinctus	94.67	0.00e+00	2237.00
IUUC-Dor-030736	Dipodomys ordii	86.97	0.00e+00	1003.00
IUUC-Dse-031402	Dothistroma septosporum	39.88	4.00e-60	227.00
IUUC-Dme-032039	Drosophila melanogaster	59.20	1.00e-119	424.00
IUUC-Eca-034255	Equus caballus	97.84	0.00e+00	2247.00
IUUC-Eeu-035038	Erinaceus europaeus	98.83	0.00e+00	1196.00
IUUC-Fca-035786	Felis catus	97.61	0.00e+00	2304.00
IUUC-Fal-037589	Ficedula albicollis	83.51	0.00e+00	2041.00
IUUC-Gmo-038781	Gadus morhua	63.55	0.00e+00	685.00
IUUC-Gga-041103	Gallus gallus	85.59	0.00e+00	1136.00
IUUC-Gac-041304	Gasterosteus aculeatus	61.69	0.00e+00	1499.00
IUUC-Ggo-044522	Gorilla gorilla	95.63	0.00e+00	1714.00
IUUC-Hsa-045877	Homo sapiens	96.22	0.00e+00	2267.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	97.47	0.00e+00	1328.00
IUUC-Kpa-049384	Komagataella pastoris	39.67	9.00e-54	204.00
IUUC-Lch-049950	Latimeria chalumnae	77.68	0.00e+00	1903.00
IUUC-Loc-051972	Lepisosteus oculatus	76.53	0.00e+00	1095.00
IUUC-Lma-053190	Leptosphaeria maculans	43.35	3.00e-59	224.00
IUUC-Laf-053623	Loxodonta africana	96.18	0.00e+00	2210.00
IUUC-Mcc-054943	Macaca mulatta	96.46	0.00e+00	2259.00
IUUC-Meu-056259	Macropus eugenii	85.82	0.00e+00	2060.00
IUUC-Mla-058890	Melampsora laricipopulina	49.22	1.00e-70	259.00
IUUC-Mga-059671	Meleagris gallopavo	84.68	0.00e+00	1988.00
IUUC-Mvi-060481	Microbotryum violaceum	43.33	7.00e-65	242.00
IUUC-Mmr-061003	Microcebus murinus	96.79	0.00e+00	2318.00
IUUC-Mmu-063584	Mus musculus	95.34	0.00e+00	2260.00
IUUC-Mpu-066056	Mustela putorius furo	97.25	0.00e+00	2309.00
IUUC-Mlu-067850	Myotis lucifugus	96.04	0.00e+00	2306.00
IUUC-Nfi-068537	Neosartorya fischeri	43.71	1.00e-63	239.00
IUUC-Nle-069837	Nomascus leucogenys	93.02	0.00e+00	2024.00
IUUC-Opr-070943	Ochotona princeps	92.55	0.00e+00	2140.00
IUUC-Ont-071663	Oreochromis niloticus	65.90	0.00e+00	1582.00
IUUC-Oan-072934	Ornithorhynchus anatinus	75.78	0.00e+00	1255.00
IUUC-Ocu-074706	Oryctolagus cuniculus	96.92	0.00e+00	2316.00
IUUC-Ola-086543	Oryzias latipes	63.88	0.00e+00	1563.00
IUUC-Oga-088671	Otolemur garnettii	83.99	0.00e+00	1011.00
IUUC-Oar-089560	Ovis aries	94.92	0.00e+00	2292.00
IUUC-Ptr-090875	Pan troglodytes	96.22	0.00e+00	2289.00
IUUC-Pan-091788	Papio anubis	93.62	0.00e+00	2206.00
IUUC-Psi-093382	Pelodiscus sinensis	84.27	0.00e+00	2037.00
IUUC-Pma-094687	Petromyzon marinus	57.10	4.00e-92	332.00
IUUC-Pno-094984	Phaeosphaeria nodorum	44.87	8.00e-61	229.00
IUUC-Pfo-096272	Poecilia formosa	63.38	0.00e+00	1509.00
IUUC-Pab-097907	Pongo abelii	91.76	0.00e+00	2116.00
IUUC-Pca-100628	Procavia capensis	86.74	0.00e+00	1858.00
IUUC-Pva-102956	Pteropus vampyrus	94.97	0.00e+00	1191.00
IUUC-Pgr-103554	Puccinia graminis	47.65	2.00e-72	266.00
IUUC-Ptt-103859	Puccinia triticina	45.85	1.00e-72	268.00
IUUC-Pte-104241	Pyrenophora teres	41.84	3.00e-59	224.00
IUUC-Pyt-104741	Pyrenophora triticirepentis	41.84	1.00e-58	222.00
IUUC-Rno-105722	Rattus norvegicus	95.10	0.00e+00	1825.00
IUUC-Sce-106445	Saccharomyces cerevisiae	44.07	7.00e-49	188.00
IUUC-Sha-106626	Sarcophilus harrisii	81.47	0.00e+00	1835.00
IUUC-Spo-108120	Schizosaccharomyces pombe	30.50	1.00e-47	185.00
IUUC-Sre-115112	Sporisorium reilianum	40.16	2.00e-57	217.00
IUUC-Ssc-115918	Sus scrofa	97.34	0.00e+00	1776.00
IUUC-Tgu-117229	Taeniopygia guttata	74.19	0.00e+00	1110.00
IUUC-Tru-118638	Takifugu rubripes	69.55	0.00e+00	994.00
IUUC-Tsy-118820	Tarsius syrichta	92.74	0.00e+00	771.00
IUUC-Tme-127054	Tuber melanosporum	40.15	1.00e-52	202.00
IUUC-Tbe-127654	Tupaia belangeri	80.70	0.00e+00	1705.00
IUUC-Ttr-128821	Tursiops truncatus	90.40	0.00e+00	2092.00
IUUC-Uma-129458	Ustilago maydis	39.15	2.00e-57	216.00
IUUC-Xtr-131823	Xenopus tropicalis	74.85	0.00e+00	1753.00
IUUC-Xma-133305	Xiphophorus maculatus	64.72	0.00e+00	1538.00
IUUC-Yli-134626	Yarrowia lipolytica	42.36	2.00e-55	209.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence