iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049349

Ensembl Protein ID

CAY70048

UniProt Accession

C4R3L1; C4R3L1_KOMPG

Genbank Protein ID

CAY70048.1

Protein Name

Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C ter

Genbank Nucleotide ID

FN392321

Gene Name

PAS_chr3_0117

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr3_0117	CAY70048	CAY70048

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.20e-41	139.3	919	1249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 82   eefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk.......sqik.clecdnvssreepfldl 172
           + ++  +qqD+ E+++ +l qle++ k                     + +++++++++l+++lF g++k       +++k   +  +v ++ e f++l
   Q: 919  NALELGRQQDVTECIENVLFQLESASKP-------------------TSLDSDDQEQNDLVKELFYGRTKqilqpvdKETKeNITDSSVRTKVERFVSL 998
           4567899*****************9922...................2345677888999999999999966555553333133344445899****** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.... 267
            +++ ++ +    +l d+L+ +++e+ ++           ++ +++++l++++lP++L ++ +R++f++e++ + k  + + f ++L +++++++    
   Q: 999  LVNIGDHPK----DLYDALDTYFTEDLIDL----------DDGQVKRSLTITELPKFLQIQVQRVQFDRERGIPFKALDPLPFHEKLYMDRYLETdnee 1083
           *****9996....8**************94..........3345799**********************************************995555 PP
   S: 268  .................peekqke........................................................................... 274
                                  +                                                                           
   Q: 1084 lilkrkeifqwkneiskL-----Nrrkdeilvpsshsmtprnaliatkefleaqkelpgdiqatestlitlqkeidilnselqtinsrlseleekcqhq 1177
           555555555555555550.....0555555555555555666666666666666666666666666666677777777777777777777777777778 PP
   S: 275  .....kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg...staYvlfYkr 337
                ++ Y+++a+ +H G++s GHY++y+++ +++ + +++D+++tev+ +ev ++++   +t+Y l++ r
   Q: 1178 fdqfkNTGYSIFAIFIHRGEASYGHYWVYIRDPTRNiYRKYNDETITEVPISEVFNFSEsntATPYFLVFVR 1249
           88898***************************99999*******************9999999****99865 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MPDQVPSAST NVNNPFAQLE AYDFSKSKIF KTSNRLIDDI KNSVLFLEQF SILNLPAVDY 60
ATQLSLQYQN RQINESFKLV LLNNQLDFAP TVSTEQLPNG TRTVFRGLIV QDTVHGIPIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAGATC AGGTTCCCAG TGCTAGCACA AATGTGAACA ATCCTTTTGC ACAATTGGAG 60
GCGTATGATT TTTCGAAATC CAAAATTTTC AAGACTTCCA ATCGATTAAT TGATGATATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR025305--UCH_repeat_domain
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS50235--USP_3

Pfam

PF13446--RPT
PF00443--UCH

Gene Ontology

GO:0005623--C:cell
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0010992--P:ubiquitin homeostasis
GO:0043162--P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

KEGG

ppa:PAS_chr3_0117

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	27.75	1.00e-10	60.50
IUUC-Apl-004010	Anas platyrhynchos	34.38	5.00e-11	61.60
IUUC-Ago-007865	Ashbya gossypii	53.00	2.00e-100	358.00
IUUC-Acl-008164	Aspergillus clavatus	30.53	2.00e-93	335.00
IUUC-Afl-008717	Aspergillus flavus	30.01	3.00e-81	295.00
IUUC-Afu-008871	Aspergillus fumigatus	29.56	2.00e-89	322.00
IUUC-Ani-009503	Aspergillus nidulans	28.48	7.00e-79	286.00
IUUC-Ang-009577	Aspergillus niger	29.33	5.00e-88	317.00
IUUC-Aor-009928	Aspergillus oryzae	29.13	8.00e-59	220.00
IUUC-Ate-010275	Aspergillus terreus	29.90	5.00e-92	330.00
IUUC-Ame-010624	Astyanax mexicanus	35.38	6.00e-10	57.40
IUUC-Bgr-011993	Blumeria graminis	28.56	4.00e-75	274.00
IUUC-Bta-013166	Bos taurus	28.27	8.00e-11	60.80
IUUC-Bci-013999	Botrytis cinerea	28.23	1.00e-79	289.00
IUUC-Cel-018346	Caenorhabditis elegans	20.40	5.00e-08	52.00
IUUC-Cja-019150	Callithrix jacchus	28.27	3.00e-11	62.00
IUUC-Cfa-020649	Canis familiaris	27.75	1.00e-10	60.10
IUUC-Cpo-021807	Cavia porcellus	28.27	3.00e-11	62.40
IUUC-Csa-023388	Chlorocebus sabaeus	27.75	1.00e-10	60.10
IUUC-Cho-024343	Choloepus hoffmanni	35.38	3.00e-09	55.50
IUUC-Cin-025302	Ciona intestinalis	30.36	6.00e-09	53.50
IUUC-Csv-025911	Ciona savignyi	29.37	3.00e-10	58.50
IUUC-Cgl-026575	Colletotrichum gloeosporioides	24.53	6.00e-17	81.30
IUUC-Cne-026803	Cryptococcus neoformans	27.49	1.00e-21	97.10
IUUC-Cme-027167	Cyanidioschyzon merolae	25.10	7.00e-14	70.90
IUUC-Dre-028016	Danio rerio	26.00	6.00e-09	54.70
IUUC-Dno-029495	Dasypus novemcinctus	28.27	6.00e-11	61.20
IUUC-Dor-030948	Dipodomys ordii	29.10	2.00e-11	62.80
IUUC-Dse-031290	Dothistroma septosporum	27.01	4.00e-29	121.00
IUUC-Ete-032828	Echinops telfairi	31.51	2.00e-09	56.20
IUUC-Eca-033214	Equus caballus	35.38	3.00e-09	54.30
IUUC-Eeu-034458	Erinaceus europaeus	30.67	2.00e-09	56.20
IUUC-Fca-035876	Felis catus	27.75	2.00e-10	59.70
IUUC-Fal-037062	Ficedula albicollis	33.33	1.00e-08	53.90
IUUC-Fox-037752	Fusarium oxysporum	26.72	4.00e-36	144.00
IUUC-Fso-038114	Fusarium solani	23.36	5.00e-20	91.70
IUUC-Gmo-039593	Gadus morhua	27.86	1.00e-11	63.90
IUUC-Ggr-039843	Gaeumannomyces graminis	31.17	6.00e-17	81.30
IUUC-Gga-040817	Gallus gallus	27.75	2.00e-09	55.80
IUUC-Gac-041867	Gasterosteus aculeatus	34.78	2.00e-10	59.70
IUUC-Ggo-044939	Gorilla gorilla	28.27	3.00e-11	62.00
IUUC-Hsa-046204	Homo sapiens	28.27	4.00e-11	62.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	31.08	3.00e-09	54.70
IUUC-Lch-049692	Latimeria chalumnae	36.23	4.00e-10	58.20
IUUC-Loc-052070	Lepisosteus oculatus	33.85	4.00e-09	55.50
IUUC-Lma-053078	Leptosphaeria maculans	25.67	5.00e-56	211.00
IUUC-Laf-054426	Loxodonta africana	28.27	3.00e-11	62.00
IUUC-Mcc-055858	Macaca mulatta	28.27	4.00e-11	62.00
IUUC-Meu-056416	Macropus eugenii	34.78	1.00e-09	57.00
IUUC-Mor-057281	Magnaporthe oryzae	24.93	2.00e-14	72.80
IUUC-Mpo-057451	Magnaporthe poae	34.97	5.00e-16	78.60
IUUC-Mla-058944	Melampsora laricipopulina	34.99	2.00e-54	206.00
IUUC-Mga-059808	Meleagris gallopavo	27.75	2.00e-09	56.20
IUUC-Mmr-060987	Microcebus murinus	28.27	4.00e-11	61.60
IUUC-Mdo-061955	Monodelphis domestica	34.78	2.00e-09	57.40
IUUC-Mmu-064245	Mus musculus	28.27	7.00e-11	61.20
IUUC-Mpu-066304	Mustela putorius furo	27.75	1.00e-10	60.50
IUUC-Mlu-067139	Myotis lucifugus	28.27	4.00e-11	62.00
IUUC-Nfi-068458	Neosartorya fischeri	30.20	2.00e-95	342.00
IUUC-Ncr-068739	Neurospora crassa	23.37	3.00e-29	122.00
IUUC-Nle-069075	Nomascus leucogenys	28.27	4.00e-11	62.00
IUUC-Opr-070214	Ochotona princeps	33.85	3.00e-08	52.40
IUUC-Ont-072386	Oreochromis niloticus	29.34	6.00e-11	61.60
IUUC-Oan-073054	Ornithorhynchus anatinus	29.47	6.00e-10	57.80
IUUC-Ocu-074102	Oryctolagus cuniculus	28.27	6.00e-11	61.20
IUUC-Ola-086393	Oryzias latipes	33.33	2.00e-10	59.30
IUUC-Oga-088939	Otolemur garnettii	28.27	4.00e-11	62.00
IUUC-Oar-090266	Ovis aries	27.75	2.00e-10	59.70
IUUC-Ptr-090546	Pan troglodytes	28.27	4.00e-11	61.60
IUUC-Pan-092311	Papio anubis	28.27	4.00e-11	62.00
IUUC-Psi-093459	Pelodiscus sinensis	28.27	2.00e-10	58.90
IUUC-Pno-095093	Phaeosphaeria nodorum	27.07	4.00e-26	111.00
IUUC-Pfo-096466	Poecilia formosa	34.04	8.00e-11	60.80
IUUC-Pab-097608	Pongo abelii	28.27	3.00e-11	62.00
IUUC-Pca-100901	Procavia capensis	32.43	1.00e-09	56.60
IUUC-Pva-103150	Pteropus vampyrus	28.04	4.00e-10	58.50
IUUC-Pgr-103515	Puccinia graminis	39.06	4.00e-31	128.00
IUUC-Ptt-103803	Puccinia triticina	29.32	7.00e-11	60.10
IUUC-Pte-104300	Pyrenophora teres	26.35	5.00e-57	214.00
IUUC-Pyt-104434	Pyrenophora triticirepentis	25.06	2.00e-47	182.00
IUUC-Rno-105727	Rattus norvegicus	28.27	6.00e-11	61.20
IUUC-Sce-106441	Saccharomyces cerevisiae	36.59	1.00e-172	598.00
IUUC-Sha-107051	Sarcophilus harrisii	27.37	3.00e-10	58.90
IUUC-Sja-107936	Schizosaccharomyces japonicus	29.20	3.00e-83	301.00
IUUC-Spo-108381	Schizosaccharomyces pombe	30.44	1.00e-87	316.00
IUUC-Ssl-108532	Sclerotinia sclerotiorum	28.43	1.00e-82	299.00
IUUC-Sar-113097	Sorex araneus	35.38	6.00e-09	54.70
IUUC-Sre-115145	Sporisorium reilianum	29.56	2.00e-39	156.00
IUUC-Ssc-115877	Sus scrofa	28.12	4.00e-11	62.00
IUUC-Tgu-116609	Taeniopygia guttata	34.38	4.00e-11	61.60
IUUC-Tru-118135	Takifugu rubripes	36.92	9.00e-11	60.50
IUUC-Tsy-118971	Tarsius syrichta	41.30	2.00e-08	52.40
IUUC-Tni-120139	Tetraodon nigroviridis	29.57	1.00e-11	63.20
IUUC-Tre-122145	Trichoderma reesei	26.23	2.00e-22	99.40
IUUC-Tvi-122548	Trichoderma virens	25.31	1.00e-22	100.00
IUUC-Tme-126928	Tuber melanosporum	43.64	3.00e-71	261.00
IUUC-Tbe-127549	Tupaia belangeri	27.37	2.00e-08	53.10
IUUC-Ttr-128896	Tursiops truncatus	35.38	6.00e-09	54.70
IUUC-Uma-129338	Ustilago maydis	26.97	2.00e-52	199.00
IUUC-Vda-129742	Verticillium dahliae	28.40	2.00e-16	80.10
IUUC-Vpa-130500	Vicugna pacos	35.38	6.00e-09	54.70
IUUC-Xtr-132896	Xenopus tropicalis	29.32	5.00e-11	61.20
IUUC-Xma-133995	Xiphophorus maculatus	34.04	1.00e-10	60.80
IUUC-Yli-134560	Yarrowia lipolytica	34.28	3.00e-131	461.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence