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Tag Content
UUCD2 ID IUUC-Ocu-074102
UUCD1 version UUC-OrC-01059
Ensembl Protein ID ENSOCUP00000004100.3
UniProt Accession G1SMF4; G1SMF4_RABIT
Genbank Protein ID ENSOCUP00000004100
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAGW02017006
Gene Name USP25
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOCUG00000004742.3 ENSOCUT00000004744.3 ENSOCUP00000004100.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 4.40e-64 216.8 197 683
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+r+l+l+    ++ ++l+++++++++ +++++l+ lf+ l+ +k+k+v+p++ +++lk++ ++ +
   Q: 197  VGLKNVGNTCWFSAVIQSLFNLLEFRRLVLNykppSNAQDLPRNQKEHRNLPFMRELRYLFALLVGTKRKYVDPSRAVEILKDAFKS-N 284
           6******************************99988889999999999999*******************************99997.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
            ++qqD++Ef++ lld le+++++                  + +ee +++k k+++++lF g++    + +  +++ + +e f +++l
   Q: 285  DSQQQDVSEFTHKLLDWLEDAFQM------------------KAEEETDEEKPKNPMVELFYGRFLAVGVLE--GKKFENTEMFGQYPL 353
           **********************33..................123456788999************777664..444556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ + e e+e+   +++e+  k+    +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp+ L l++
   Q: 354  QVNGFK-----DLHECLEAAMIEGEIES---LHSENSGKS---GQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPQVLYLDR 431
           ******.....9**************96...999998865...589******************************************* PP
   S: 264  fcts..................................................................................... 267
           ++++                                                                                     
   Q: 432  YMHRnreitrikrdeikrlkdyltvlqqrlerylsygsgpkrfplvdvlqyalefasskpvctspvddidatsppsgsvpaqtlpstae 520
           ****8888888888888888888887777777777777777777777777777777777777777777777777777777766666666 PP
   S: 268  ..............peekqke.................................................................... 274
                               +                                                                    
   Q: 521  pqgapsselpstspA-----Svaaissrsvihkpftqsrippdlpmhpaprhiteeelsvlesclhrwrteiendtrdlqesisrihrt 604
           666665555555550.....055555555555555555555555555566666666666666666666666666777777788888888 PP
   S: 275  ...........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                      ++ Y+L+av+vH+G+++ GHY+ay+ +++++ W++++D  Vt++++ee ++++      ++aY+l+Y 
   Q: 605  ielmysdksmiQVPYRLHAVLVHEGQANAGHYWAYIFDHRENrWMKYNDIAVTKSSWEELVRDSFggyrnASAYCLMYI 683
           88888888888**************************965556***************99997779************6 PP
   
Organism Oryctolagus cuniculus
Protein Sequence
(Fasta)
MTVEQNVLQQ SAAQKHQQTF LNQLREITGI NDTQILQQAL KDSNGNLELA VAFLTSKNAK 60
TPQQEETTYY QTALPGNDRY ISVGSQADTR KKQYMHTRTR CTTIEQSKFG SKDKRDLDVI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ocu-074102|DUB,USP|Oryctolagus cuniculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCAGCAGCAG GCGGAAGTCG GGGAGGGGAG GAGGACAGCG CCCATTCCGG CCCGGCCGCC 60
TCCCCTCCGT CCCCTCGCGC CAGTCCCCGC AGTGCCCCGC GAGCCGGCGG TGAAGGAGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ocu-074102|DUB,USP|Oryctolagus cuniculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
PF02809--UIM
SMART

SM00726--UIM
Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:1904293--P:negative regulation of ERAD pathway
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001340 Ailuropoda melanoleuca 91.92 0.00e+00 2056.00
IUUC-Apl-004030 Anas platyrhynchos 81.14 0.00e+00 1885.00
IUUC-Aca-004753 Anolis carolinensis 65.57 0.00e+00 1063.00
IUUC-Afu-008871 Aspergillus fumigatus 23.94 1.00e-13 72.40
IUUC-Ani-009503 Aspergillus nidulans 33.96 1.00e-11 65.90
IUUC-Ame-010624 Astyanax mexicanus 71.10 0.00e+00 1149.00
IUUC-Bta-013166 Bos taurus 93.28 0.00e+00 1425.00
IUUC-Cel-018346 Caenorhabditis elegans 28.10 7.00e-29 123.00
IUUC-Cja-019150 Callithrix jacchus 94.88 0.00e+00 2127.00
IUUC-Cfa-020649 Canis familiaris 94.97 0.00e+00 2145.00
IUUC-Cpo-021807 Cavia porcellus 90.71 0.00e+00 2129.00
IUUC-Csa-023388 Chlorocebus sabaeus 94.64 0.00e+00 2127.00
IUUC-Cin-025302 Ciona intestinalis 37.33 6.00e-96 344.00
IUUC-Csv-025911 Ciona savignyi 34.33 3.00e-128 452.00
IUUC-Cgl-026575 Colletotrichum gloeosporioides 55.32 1.00e-10 62.80
IUUC-Dre-028016 Danio rerio 73.37 0.00e+00 1694.00
IUUC-Dno-029495 Dasypus novemcinctus 96.18 0.00e+00 2207.00
IUUC-Dor-030948 Dipodomys ordii 81.90 0.00e+00 1501.00
IUUC-Fca-035876 Felis catus 93.81 0.00e+00 1464.00
IUUC-Fal-036762 Ficedula albicollis 84.70 0.00e+00 1134.00
IUUC-Gmo-039490 Gadus morhua 70.34 0.00e+00 1578.00
IUUC-Gga-040817 Gallus gallus 82.78 0.00e+00 1954.00
IUUC-Gac-042473 Gasterosteus aculeatus 70.05 0.00e+00 1609.00
IUUC-Ggo-044939 Gorilla gorilla 90.20 0.00e+00 1989.00
IUUC-Hsa-046204 Homo sapiens 94.30 0.00e+00 1454.00
IUUC-Kpa-049349 Komagataella pastoris 28.27 3.00e-10 61.20
IUUC-Lch-049572 Latimeria chalumnae 77.25 0.00e+00 1755.00
IUUC-Loc-052070 Lepisosteus oculatus 76.17 0.00e+00 1726.00
IUUC-Lma-053078 Leptosphaeria maculans 30.56 4.00e-12 67.40
IUUC-Laf-054426 Loxodonta africana 97.53 0.00e+00 1334.00
IUUC-Mcc-055858 Macaca mulatta 94.80 0.00e+00 2159.00
IUUC-Mga-059808 Meleagris gallopavo 82.62 0.00e+00 1352.00
IUUC-Mmr-060987 Microcebus murinus 95.05 0.00e+00 2113.00
IUUC-Mmu-064245 Mus musculus 89.71 0.00e+00 1442.00
IUUC-Mpu-066304 Mustela putorius furo 94.13 0.00e+00 2102.00
IUUC-Mlu-067139 Myotis lucifugus 92.67 0.00e+00 1479.00
IUUC-Nfi-068458 Neosartorya fischeri 22.72 2.00e-16 81.60
IUUC-Nle-069075 Nomascus leucogenys 94.55 0.00e+00 1455.00
IUUC-Ont-072150 Oreochromis niloticus 71.69 0.00e+00 1688.00
IUUC-Oan-073054 Ornithorhynchus anatinus 77.39 0.00e+00 1736.00
IUUC-Ola-086529 Oryzias latipes 68.02 0.00e+00 1541.00
IUUC-Oga-088939 Otolemur garnettii 91.97 0.00e+00 1442.00
IUUC-Oar-090266 Ovis aries 93.94 0.00e+00 2089.00
IUUC-Ptr-090546 Pan troglodytes 94.18 0.00e+00 1450.00
IUUC-Pan-092311 Papio anubis 94.71 0.00e+00 2159.00
IUUC-Psi-093459 Pelodiscus sinensis 86.96 0.00e+00 1172.00
IUUC-Pfo-096726 Poecilia formosa 71.49 0.00e+00 1684.00
IUUC-Pab-097608 Pongo abelii 91.74 0.00e+00 2009.00
IUUC-Pca-100718 Procavia capensis 82.79 0.00e+00 1460.00
IUUC-Pva-103150 Pteropus vampyrus 90.97 0.00e+00 1530.00
IUUC-Rno-105727 Rattus norvegicus 90.71 0.00e+00 1407.00
IUUC-Sha-107051 Sarcophilus harrisii 86.33 0.00e+00 1368.00
IUUC-Ssl-108532 Sclerotinia sclerotiorum 28.85 4.00e-09 57.40
IUUC-Sar-113097 Sorex araneus 83.47 0.00e+00 1867.00
IUUC-Sre-115145 Sporisorium reilianum 27.78 6.00e-11 63.90
IUUC-Ssc-115877 Sus scrofa 90.67 0.00e+00 1413.00
IUUC-Tgu-117473 Taeniopygia guttata 74.52 0.00e+00 1704.00
IUUC-Tru-118135 Takifugu rubripes 64.06 0.00e+00 1401.00
IUUC-Tsy-119471 Tarsius syrichta 89.29 0.00e+00 1872.00
IUUC-Tni-120139 Tetraodon nigroviridis 67.56 0.00e+00 995.00
IUUC-Tbe-127549 Tupaia belangeri 85.40 0.00e+00 1873.00
IUUC-Ttr-128896 Tursiops truncatus 87.76 0.00e+00 1951.00
IUUC-Vda-129742 Verticillium dahliae 22.74 3.00e-12 68.20
IUUC-Vpa-130500 Vicugna pacos 89.92 0.00e+00 1319.00
IUUC-Xtr-132896 Xenopus tropicalis 78.89 0.00e+00 1269.00
Created Date 25-Jun-2017

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