iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000000185.1	ENSONIT00000000238.1	ENSONIP00000000239.1
ENSONIG00000000185.1	ENSONIT00000000239.1	ENSONIP00000000240.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-108	363.4	748	1078

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n+p l+e++++  + e++n+ n  ++kge+++++  ++++lw +  k +spr+++ +++k++e+f g
   Q: 748  TGLRNLGNTCYMNSILQCLCNTPALAEYFNNnCYLEDINRHNILGHKGEVAEEFGVIMKALWAGLYKCISPRDFKITIGKINEQFAG 834
           7******************************99****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           y+qqD+qE+l fl+d+l+e+l+k +n ++ +eee+d  +l+d+     a++k+k  n+s+i+ lFqgq+ks+++cl+c+++s ++e+
   Q: 835  YDQQDSQELLLFLMDGLHEDLNKADNRKRYKEEEND--HLDDQtgadlAWSKHKLLNESIIVALFQGQFKSTVQCLTCHRKSRTFET 919
           *********************885555555555554..4444455666*************************************** PP
   S: 169  fldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvef 255
           f++lslp+ + +++   slqdcL+ f+kee+l+++nk++c++ck++++++kkl+++k+P++L +hLkRfs++ +   ++k++++v+f
   Q: 920  FMYLSLPLASTSKC---SLQDCLRLFSKEEKLTDNNKVFCRHCKAHRDSTKKLEIWKVPPILLVHLKRFSYEGR--WKQKLQTSVDF 1001
           *************9...****************************************************99765..556******** PP
   S: 256  ple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           pl  Ldl+++++ p+++    k+Y+L++v +H+G+l++GHY+ay+kn  ++ W++fdD++V+ ++ ++v++   s aY+lfY 
   Q: 1002 PLDnLDLAQYVIGPKQS---LKRYNLYGVSNHYGGLDGGHYTAYCKNAAKQrWYKFDDHEVSDISTSSVKS---SAAYILFYS 1078
           *************9988...69*************************87778*******************...********7 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MPAVSTGVKE LYLSTSLGDL NKKAEIKPDK TSTRNYVQSA CKIFKAAEEC RLDRDEEKAY 60
VLYMKYLTVY DIIKKRPEFK QQPEYYITML GTNSFKKAIE EAEKLSESLK LRYEEVEVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGGATAGG ATAGGATCAA ACTTTATTGT CATTAAACAT GTATAAATAC AGGGTAACAA 60
AATATAGTTT GCATCTAATC AGAAGTGCAA GGTGCATTAA GTGCATTAAG AGCAGATTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00581--Rhodanese
PF00443--UCH
PF08969--USP8_dimer

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	77.24	0.00e+00	768.00
IUUC-Apl-003226	Anas platyrhynchos	57.88	0.00e+00	1142.00
IUUC-Aca-004936	Anolis carolinensis	55.24	0.00e+00	1032.00
IUUC-Ago-007959	Ashbya gossypii	36.34	1.00e-55	211.00
IUUC-Acl-008102	Aspergillus clavatus	32.42	1.00e-54	208.00
IUUC-Afl-008604	Aspergillus flavus	31.87	3.00e-53	204.00
IUUC-Afu-009001	Aspergillus fumigatus	32.50	1.00e-53	205.00
IUUC-Ani-009291	Aspergillus nidulans	31.59	5.00e-53	203.00
IUUC-Ang-009844	Aspergillus niger	31.33	3.00e-53	203.00
IUUC-Aor-010098	Aspergillus oryzae	31.87	1.00e-52	201.00
IUUC-Ate-010585	Aspergillus terreus	32.04	4.00e-53	203.00
IUUC-Ame-011029	Astyanax mexicanus	73.61	6.00e-95	340.00
IUUC-Bta-013008	Bos taurus	71.58	0.00e+00	773.00
IUUC-Bol-015281	Brassica oleracea	40.60	7.00e-53	201.00
IUUC-Bra-017228	Brassica rapa	40.60	2.00e-52	200.00
IUUC-Cel-018482	Caenorhabditis elegans	32.23	4.00e-54	206.00
IUUC-Cja-019173	Callithrix jacchus	77.28	0.00e+00	770.00
IUUC-Cfa-021243	Canis familiaris	77.24	0.00e+00	769.00
IUUC-Cpo-021522	Cavia porcellus	59.36	0.00e+00	1143.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	44.64	8.00e-87	313.00
IUUC-Csa-023616	Chlorocebus sabaeus	77.28	0.00e+00	766.00
IUUC-Cho-024381	Choloepus hoffmanni	67.90	0.00e+00	637.00
IUUC-Cin-025287	Ciona intestinalis	47.56	5.00e-95	342.00
IUUC-Csv-026253	Ciona savignyi	46.83	1.00e-84	308.00
IUUC-Cne-026821	Cryptococcus neoformans	39.44	6.00e-75	276.00
IUUC-Dre-028440	Danio rerio	64.71	0.00e+00	810.00
IUUC-Dno-029039	Dasypus novemcinctus	76.67	0.00e+00	769.00
IUUC-Dor-031043	Dipodomys ordii	83.41	3.00e-118	419.00
IUUC-Dse-031463	Dothistroma septosporum	29.81	3.00e-45	177.00
IUUC-Dme-032089	Drosophila melanogaster	43.99	3.00e-87	316.00
IUUC-Ete-033040	Echinops telfairi	74.75	2.00e-174	606.00
IUUC-Eca-033449	Equus caballus	77.24	0.00e+00	792.00
IUUC-Eeu-034693	Erinaceus europaeus	84.30	9.00e-112	398.00
IUUC-Fca-035794	Felis catus	76.51	0.00e+00	734.00
IUUC-Fal-037322	Ficedula albicollis	77.03	0.00e+00	757.00
IUUC-Gmo-038584	Gadus morhua	76.08	0.00e+00	811.00
IUUC-Gga-041188	Gallus gallus	77.03	0.00e+00	758.00
IUUC-Gac-041850	Gasterosteus aculeatus	91.55	0.00e+00	904.00
IUUC-Ggo-045565	Gorilla gorilla	77.48	0.00e+00	773.00
IUUC-Hsa-046438	Homo sapiens	77.48	0.00e+00	772.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	58.04	0.00e+00	1146.00
IUUC-Kpa-049321	Komagataella pastoris	32.69	5.00e-48	186.00
IUUC-Lch-050485	Latimeria chalumnae	77.10	0.00e+00	785.00
IUUC-Loc-052769	Lepisosteus oculatus	79.28	0.00e+00	804.00
IUUC-Lma-053021	Leptosphaeria maculans	33.06	2.00e-56	214.00
IUUC-Laf-053432	Loxodonta africana	75.90	0.00e+00	766.00
IUUC-Mcc-055823	Macaca mulatta	77.28	0.00e+00	770.00
IUUC-Meu-056099	Macropus eugenii	84.33	1.00e-143	504.00
IUUC-Mla-059089	Melampsora laricipopulina	41.67	2.00e-73	271.00
IUUC-Mga-059739	Meleagris gallopavo	76.63	0.00e+00	754.00
IUUC-Mvi-060559	Microbotryum violaceum	40.78	2.00e-80	295.00
IUUC-Mmr-061158	Microcebus murinus	77.69	0.00e+00	771.00
IUUC-Mdo-061801	Monodelphis domestica	76.47	0.00e+00	760.00
IUUC-Mmu-063665	Mus musculus	50.91	2.00e-110	394.00
IUUC-Mpu-066738	Mustela putorius furo	77.03	0.00e+00	766.00
IUUC-Mlu-067307	Myotis lucifugus	77.64	0.00e+00	782.00
IUUC-Nfi-068410	Neosartorya fischeri	32.50	1.00e-53	205.00
IUUC-Nle-069314	Nomascus leucogenys	77.28	0.00e+00	770.00
IUUC-Opr-070378	Ochotona princeps	71.48	5.00e-105	376.00
IUUC-Oan-073537	Ornithorhynchus anatinus	74.24	0.00e+00	756.00
IUUC-Ocu-074193	Oryctolagus cuniculus	58.62	0.00e+00	1159.00
IUUC-Ola-086622	Oryzias latipes	77.48	0.00e+00	1470.00
IUUC-Oga-088271	Otolemur garnettii	76.88	0.00e+00	772.00
IUUC-Oar-090431	Ovis aries	71.64	0.00e+00	773.00
IUUC-Ptr-091339	Pan troglodytes	57.26	0.00e+00	1147.00
IUUC-Pan-092266	Papio anubis	80.12	3.00e-157	547.00
IUUC-Psi-093187	Pelodiscus sinensis	53.19	1.00e-112	401.00
IUUC-Pma-094626	Petromyzon marinus	55.64	2.00e-141	495.00
IUUC-Pfo-096463	Poecilia formosa	90.96	0.00e+00	939.00
IUUC-Pab-097645	Pongo abelii	77.28	0.00e+00	769.00
IUUC-Pva-103222	Pteropus vampyrus	80.89	0.00e+00	634.00
IUUC-Pgr-103408	Puccinia graminis	37.30	1.00e-56	215.00
IUUC-Ptt-103699	Puccinia triticina	47.20	5.00e-68	253.00
IUUC-Pte-104348	Pyrenophora teres	29.13	7.00e-41	162.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	30.49	7.00e-53	202.00
IUUC-Rno-105510	Rattus norvegicus	58.50	0.00e+00	1138.00
IUUC-Sce-106435	Saccharomyces cerevisiae	34.59	2.00e-56	214.00
IUUC-Sha-106879	Sarcophilus harrisii	76.21	0.00e+00	758.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	35.31	7.00e-50	192.00
IUUC-Smo-108711	Selaginella moellendorffii	35.88	5.00e-53	201.00
IUUC-Sar-113019	Sorex araneus	53.88	0.00e+00	1059.00
IUUC-Sre-115031	Sporisorium reilianum	37.99	6.00e-72	266.00
IUUC-Ssc-116334	Sus scrofa	58.17	0.00e+00	1172.00
IUUC-Tgu-117062	Taeniopygia guttata	76.63	0.00e+00	753.00
IUUC-Tru-117908	Takifugu rubripes	81.39	0.00e+00	1615.00
IUUC-Tsy-118867	Tarsius syrichta	69.17	0.00e+00	664.00
IUUC-Tni-120206	Tetraodon nigroviridis	72.33	0.00e+00	1424.00
IUUC-Tme-127144	Tuber melanosporum	41.37	8.00e-82	299.00
IUUC-Tbe-127877	Tupaia belangeri	84.03	1.00e-69	258.00
IUUC-Ttr-128580	Tursiops truncatus	77.44	0.00e+00	769.00
IUUC-Uma-129340	Ustilago maydis	39.78	2.00e-74	274.00
IUUC-Vpa-130541	Vicugna pacos	75.41	0.00e+00	742.00
IUUC-Xtr-132161	Xenopus tropicalis	71.31	0.00e+00	736.00
IUUC-Xma-134271	Xiphophorus maculatus	90.77	0.00e+00	943.00
IUUC-Yli-134561	Yarrowia lipolytica	36.97	1.00e-58	221.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence