iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Yli-134433

Ensembl Protein ID

CAG79011

UniProt Accession

Q6C7D0; TFB3_YARLI

Genbank Protein ID

CAG79011.1

Protein Name

RNA polymerase II transcription factor B subunit 3; RNA polymerase II transcription factor B 38 kDa subunit; RNA polymerase II transcription factor B p38 subunit

Genbank Nucleotide ID

CR382131

Gene Name

TFB3; YALI0E01826g

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YALI0_E01826g	CAG79011	CAG79011

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	42.90	2.00e-64	241.00	IUUC-Sce-106405

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Yarrowia lipolytica

Functional Description
(View)

Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA. TFIIH as CTD kinase activity and DNA-dependent ATPase activity, and is essential for polymerase II transcription (By similarity).

Protein Sequence
(Fasta)

MSEDGDICPI CKSSRYLNPD MKFLVNPQCY HKMCESCVDR LFAYGPVTCP HNGCEKILRK 60
NKFKTQIFED VAVEKEVDVR QRVMSVMNKR EDEFDTLNDY NAYLEKIEDS IFTLLNGTAD 120

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Nucleotide Sequence
(Fasta)

ATGAGTGAAG ATGGGGATAT ATGCCCGATC TGCAAATCCT CGCGGTACCT CAACCCGGAT 60
ATGAAATTTC TAGTCAATCC TCAATGTTAC CACAAAATGT GCGAATCGTG TGTGGATCGA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015877--Cdk-activating_kinase_MAT1_cen
IPR004575--MAT1/Tfb3
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF06391--MAT1
PF17121--zf-C3HC4_5

Gene Ontology

GO:0005829--C:cytosol
GO:0005675--C:holo TFIIH complex
GO:0070985--C:TFIIK complex
GO:0061575--F:cyclin-dependent protein serine/threonine kinase activator activity
GO:0008270--F:zinc ion binding
GO:0007049--P:cell cycle
GO:0006281--P:DNA repair
GO:0006289--P:nucleotide-excision repair
GO:0070816--P:phosphorylation of RNA polymerase II C-terminal domain
GO:1901409--P:positive regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:0000079--P:regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006366--P:transcription from RNA polymerase II promoter

KEGG

yli:YALI0E01826g

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002414	Ailuropoda melanoleuca	29.81	1.00e-32	131.00
IUUC-Atr-002627	Amborella trichopoda	38.81	3.00e-10	56.20
IUUC-Apl-003312	Anas platyrhynchos	44.74	3.00e-23	99.80
IUUC-Aca-004731	Anolis carolinensis	33.33	9.00e-32	128.00
IUUC-Aly-006244	Arabidopsis lyrata	38.16	5.00e-11	58.50
IUUC-Ath-007136	Arabidopsis thaliana	40.79	7.00e-12	61.20
IUUC-Ago-007788	Ashbya gossypii	44.34	1.00e-63	234.00
IUUC-Acl-008179	Aspergillus clavatus	35.49	1.00e-60	224.00
IUUC-Afl-008465	Aspergillus flavus	36.57	4.00e-59	219.00
IUUC-Afu-009056	Aspergillus fumigatus	36.01	1.00e-57	214.00
IUUC-Ani-009235	Aspergillus nidulans	24.91	1.00e-13	68.20
IUUC-Ang-009677	Aspergillus niger	34.83	3.00e-57	213.00
IUUC-Aor-010017	Aspergillus oryzae	36.69	3.00e-59	220.00
IUUC-Ate-010259	Aspergillus terreus	35.21	1.00e-53	201.00
IUUC-Ame-010934	Astyanax mexicanus	29.03	6.00e-26	109.00
IUUC-Bgr-012074	Blumeria graminis	35.92	1.00e-56	211.00
IUUC-Bta-013329	Bos taurus	29.81	4.00e-33	132.00
IUUC-Bci-013704	Botrytis cinerea	36.91	7.00e-58	215.00
IUUC-Bdi-014606	Brachypodium distachyon	36.71	4.00e-10	55.80
IUUC-Bol-015807	Brassica oleracea	35.48	3.00e-04	36.60
IUUC-Bra-016949	Brassica rapa	41.56	1.00e-10	57.40
IUUC-Cel-018428	Caenorhabditis elegans	31.68	1.00e-24	105.00
IUUC-Cja-019720	Callithrix jacchus	44.44	4.00e-32	129.00
IUUC-Cfa-020319	Canis familiaris	29.50	6.00e-33	132.00
IUUC-Cpo-021652	Cavia porcellus	30.43	7.00e-33	132.00
IUUC-Cre-022749	Chlamydomonas reinhardtii	37.74	3.00e-07	45.80
IUUC-Csa-023560	Chlorocebus sabaeus	29.63	4.00e-32	129.00
IUUC-Cin-025502	Ciona intestinalis	31.19	2.00e-30	123.00
IUUC-Csv-026302	Ciona savignyi	29.38	7.00e-29	119.00
IUUC-Cgl-026541	Colletotrichum gloeosporioides	30.77	2.00e-16	76.60
IUUC-Cne-027055	Cryptococcus neoformans	46.41	1.00e-34	138.00
IUUC-Cme-027128	Cyanidioschyzon merolae	37.70	1.00e-04	38.50
IUUC-Dre-027714	Danio rerio	44.60	1.00e-30	124.00
IUUC-Dno-029232	Dasypus novemcinctus	44.22	1.00e-31	127.00
IUUC-Dor-030996	Dipodomys ordii	46.05	8.00e-15	72.00
IUUC-Dse-031359	Dothistroma septosporum	37.22	8.00e-53	198.00
IUUC-Dme-031992	Drosophila melanogaster	32.92	7.00e-37	145.00
IUUC-Ete-032973	Echinops telfairi	41.67	2.00e-07	47.40
IUUC-Eca-034116	Equus caballus	29.81	6.00e-33	132.00
IUUC-Eeu-035143	Erinaceus europaeus	36.81	2.00e-20	90.50
IUUC-Fca-035960	Felis catus	29.81	1.00e-32	131.00
IUUC-Fal-037039	Ficedula albicollis	45.61	2.00e-23	100.00
IUUC-Fox-037882	Fusarium oxysporum	32.58	7.00e-44	169.00
IUUC-Fso-038318	Fusarium solani	33.02	1.00e-46	178.00
IUUC-Gmo-038905	Gadus morhua	31.53	6.00e-29	119.00
IUUC-Ggr-039857	Gaeumannomyces graminis	41.91	1.00e-24	105.00
IUUC-Gga-041216	Gallus gallus	43.54	5.00e-31	125.00
IUUC-Gac-041987	Gasterosteus aculeatus	31.17	3.00e-31	126.00
IUUC-Gma-044312	Glycine max	42.03	2.00e-11	59.70
IUUC-Ggo-044930	Gorilla gorilla	25.93	3.00e-20	90.10
IUUC-Hsa-045876	Homo sapiens	29.63	4.00e-32	129.00
IUUC-Hvu-047088	Hordeum vulgare	36.71	8.00e-10	54.70
IUUC-Itr-048476	Ictidomys tridecemlineatus	45.38	2.00e-25	106.00
IUUC-Kpa-049202	Komagataella pastoris	36.94	1.00e-53	201.00
IUUC-Lch-049886	Latimeria chalumnae	42.14	6.00e-29	119.00
IUUC-Lpe-051199	Leersia perrieri	36.71	1.00e-10	57.40
IUUC-Loc-052556	Lepisosteus oculatus	41.67	2.00e-29	120.00
IUUC-Lma-053002	Leptosphaeria maculans	36.81	5.00e-52	196.00
IUUC-Laf-054516	Loxodonta africana	31.06	2.00e-33	134.00
IUUC-Mcc-054761	Macaca mulatta	44.44	6.00e-32	129.00
IUUC-Mor-057048	Magnaporthe oryzae	47.76	3.00e-38	150.00
IUUC-Mpo-057598	Magnaporthe poae	46.36	3.00e-20	89.40
IUUC-Mtr-058131	Medicago truncatula	40.58	2.00e-11	60.10
IUUC-Mla-059009	Melampsora laricipopulina	55.86	7.00e-36	140.00
IUUC-Mga-060199	Meleagris gallopavo	42.98	3.00e-22	95.90
IUUC-Mvi-060382	Microbotryum violaceum	34.84	2.00e-35	140.00
IUUC-Mmr-061671	Microcebus murinus	31.33	7.00e-32	128.00
IUUC-Mdo-062228	Monodelphis domestica	29.50	9.00e-33	131.00
IUUC-Mmu-064416	Mus musculus	31.06	3.00e-32	130.00
IUUC-Mac-064807	Musa acuminata	38.81	1.00e-09	53.90
IUUC-Mpu-066455	Mustela putorius furo	30.43	1.00e-32	131.00
IUUC-Mlu-067325	Myotis lucifugus	44.54	2.00e-25	107.00
IUUC-Nfi-068566	Neosartorya fischeri	35.31	2.00e-58	217.00
IUUC-Ncr-068687	Neurospora crassa	33.73	2.00e-49	187.00
IUUC-Nle-069937	Nomascus leucogenys	29.63	4.00e-32	129.00
IUUC-Opr-070321	Ochotona princeps	43.14	1.00e-21	94.70
IUUC-Ont-072636	Oreochromis niloticus	30.58	1.00e-29	121.00
IUUC-Oan-072915	Ornithorhynchus anatinus	42.98	2.00e-22	96.70
IUUC-Ocu-074547	Oryctolagus cuniculus	28.09	5.00e-29	119.00
IUUC-Oba-075318	Oryza barthii	36.71	2.00e-09	53.90
IUUC-Obr-076081	Oryza brachyantha	36.71	7.00e-10	55.10
IUUC-Ogl-077072	Oryza glaberrima	36.71	2.00e-09	53.90
IUUC-Ogu-078667	Oryza glumaepatula	34.18	1.00e-09	53.90
IUUC-Oin-079796	Oryza indica	36.71	1.00e-09	54.30
IUUC-Olo-080344	Oryza longistaminata	27.55	3.00e-06	42.70
IUUC-Ome-081805	Oryza meridionalis	36.71	9.00e-10	55.10
IUUC-Oni-082783	Oryza nivara	36.71	1.00e-09	53.90
IUUC-Opu-083247	Oryza punctata	32.91	3.00e-09	53.10
IUUC-Oru-084336	Oryza rufipogon	36.71	2.00e-09	53.90
IUUC-Osa-086047	Oryza sativa	36.71	1.00e-09	54.30
IUUC-Ola-086780	Oryzias latipes	32.31	1.00e-33	134.00
IUUC-Olu-087653	Ostreococcus lucimarinus	33.87	5.00e-07	45.10
IUUC-Oga-088012	Otolemur garnettii	30.94	3.00e-32	130.00
IUUC-Oar-090274	Ovis aries	26.71	1.00e-23	101.00
IUUC-Ptr-090780	Pan troglodytes	29.63	4.00e-32	129.00
IUUC-Pan-091815	Papio anubis	43.75	9.00e-21	91.30
IUUC-Psi-093883	Pelodiscus sinensis	33.44	6.00e-32	129.00
IUUC-Pma-094717	Petromyzon marinus	33.33	4.00e-09	52.80
IUUC-Pno-094958	Phaeosphaeria nodorum	38.41	7.00e-58	215.00
IUUC-Ppa-095445	Physcomitrella patens	47.83	2.00e-09	53.50
IUUC-Pfo-096051	Poecilia formosa	43.66	5.00e-30	122.00
IUUC-Pab-097609	Pongo abelii	45.14	3.00e-32	129.00
IUUC-Pop-099460	Populus trichocarpa	42.11	4.00e-12	62.40
IUUC-Pca-101094	Procavia capensis	29.11	6.00e-25	105.00
IUUC-Ppe-101481	Prunus persica	40.58	5.00e-11	58.90
IUUC-Pva-103219	Pteropus vampyrus	44.44	5.00e-32	129.00
IUUC-Pgr-103557	Puccinia graminis	50.00	1.00e-37	148.00
IUUC-Ptt-103719	Puccinia triticina	50.00	1.00e-37	148.00
IUUC-Pte-104301	Pyrenophora teres	48.92	1.00e-39	154.00
IUUC-Pyt-104486	Pyrenophora triticirepentis	54.05	1.00e-36	144.00
IUUC-Rno-105846	Rattus norvegicus	29.19	1.00e-32	131.00
IUUC-Sce-106405	Saccharomyces cerevisiae	43.57	3.00e-64	236.00
IUUC-Sha-107594	Sarcophilus harrisii	43.86	2.00e-22	96.70
IUUC-Sja-107951	Schizosaccharomyces japonicus	34.53	2.00e-42	163.00
IUUC-Spo-108137	Schizosaccharomyces pombe	35.55	5.00e-45	172.00
IUUC-Ssl-108503	Sclerotinia sclerotiorum	36.41	5.00e-64	235.00
IUUC-Smo-109621	Selaginella moellendorffii	40.62	9.00e-13	64.30
IUUC-Sit-110672	Setaria italica	37.97	2.00e-11	60.10
IUUC-Sly-111744	Solanum lycopersicum	38.57	8.00e-11	58.20
IUUC-Stu-112343	Solanum tuberosum	38.57	8.00e-11	57.80
IUUC-Sar-113298	Sorex araneus	45.71	2.00e-32	130.00
IUUC-Sbi-113918	Sorghum bicolor	36.71	2.00e-10	57.00
IUUC-Sre-114991	Sporisorium reilianum	42.76	2.00e-28	117.00
IUUC-Ssc-116152	Sus scrofa	44.74	1.00e-23	100.00
IUUC-Tgu-116452	Taeniopygia guttata	45.71	1.00e-31	127.00
IUUC-Tru-118621	Takifugu rubripes	28.14	4.00e-28	116.00
IUUC-Tsy-119500	Tarsius syrichta	43.75	2.00e-31	127.00
IUUC-Tni-120454	Tetraodon nigroviridis	35.96	2.00e-15	74.30
IUUC-Tca-121192	Theobroma cacao	42.86	3.00e-12	62.80
IUUC-Tre-122011	Trichoderma reesei	31.63	2.00e-43	167.00
IUUC-Tvi-122317	Trichoderma virens	32.46	7.00e-45	172.00
IUUC-Tae-123854	Triticum aestivum	35.44	1.00e-09	53.90
IUUC-Tur-126556	Triticum urartu	35.44	2.00e-09	53.50
IUUC-Tme-127135	Tuber melanosporum	41.04	3.00e-44	169.00
IUUC-Tbe-127287	Tupaia belangeri	42.98	1.00e-19	88.20
IUUC-Ttr-128864	Tursiops truncatus	30.12	3.00e-33	133.00
IUUC-Uma-129539	Ustilago maydis	49.14	4.00e-31	126.00
IUUC-Vda-129713	Verticillium dahliae	35.85	2.00e-42	164.00
IUUC-Vpa-130462	Vicugna pacos	27.33	5.00e-24	102.00
IUUC-Vvi-130988	Vitis vinifera	39.13	2.00e-10	57.00
IUUC-Xtr-131830	Xenopus tropicalis	37.25	8.00e-31	124.00
IUUC-Xma-133952	Xiphophorus maculatus	43.66	4.00e-30	122.00
IUUC-Zma-134867	Zea mays	36.71	1.00e-09	53.90

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence