iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cfa-020856

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03012082

Gene Name

RAD18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005548.3	ENSCAFT00000008937.3	ENSCAFP00000008290.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/UBZ	5.50e-07	30.0	202	224

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/UBZ

   S: 2    lvCPvCqkmvdqtdfeeHlDeCl 24
           + CPvC+  ++++++++HlD+Cl
   Q: 202  VDCPVCGVNIPENHINKHLDSCL 224
           57********************8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MDSLVESRWP PGLAVMKTID DLLRCGICFD YFNIAMMIPQ CSHNYCSLCI RKFLSYKTQC 60
PTCCVTVTEP DLKNNRILDE LVKSLNFARN HLLQFALESP PISPASSSSK NLAAKVNTPV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGAAGCTC GATGTGTGCT TTTTAACCGC TTAAAGGCTC GGAGAGGCCA AGGGAAGCTC 60
CGCGCGTGCG CAGTGAGAGC GTCTTTGGCT GCGCTCCGCC CACGTACTAC AACTTCCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR006642--Znf_Rad18_put
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50800--SAP
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF02037--SAP

SMART

SM00184--RING
SM00513--SAP
SM00734--ZnF_Rad18

Gene Ontology

GO:0005813--C:centrosome
GO:0016604--C:nuclear body
GO:0042405--C:nuclear inclusion body
GO:0005634--C:nucleus
GO:0097505--C:Rad6-Rad18 complex
GO:0005657--C:replication fork
GO:0035861--C:site of double-strand break
GO:0043142--F:single-stranded DNA-dependent ATPase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0000403--F:Y-form DNA binding
GO:0008270--F:zinc ion binding
GO:0060548--P:negative regulation of cell death
GO:0051984--P:positive regulation of chromosome segregation
GO:0006301--P:postreplication repair
GO:0051865--P:protein autoubiquitination
GO:0006513--P:protein monoubiquitination
GO:0009411--P:response to UV

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002086	Ailuropoda melanoleuca	80.74	0.00e+00	807.00
IUUC-Apl-003657	Anas platyrhynchos	55.47	4.00e-105	374.00
IUUC-Aca-005369	Anolis carolinensis	74.65	5.00e-60	222.00
IUUC-Ago-007876	Ashbya gossypii	24.42	8.00e-13	68.20
IUUC-Acl-008246	Aspergillus clavatus	27.27	1.00e-28	120.00
IUUC-Afl-008666	Aspergillus flavus	27.56	6.00e-26	111.00
IUUC-Afu-009052	Aspergillus fumigatus	25.59	4.00e-28	119.00
IUUC-Ani-009488	Aspergillus nidulans	27.15	2.00e-31	130.00
IUUC-Ang-009681	Aspergillus niger	25.40	1.00e-26	114.00
IUUC-Aor-010037	Aspergillus oryzae	28.18	2.00e-27	117.00
IUUC-Ate-010516	Aspergillus terreus	38.10	5.00e-13	67.80
IUUC-Ame-010630	Astyanax mexicanus	42.79	4.00e-77	281.00
IUUC-Bgr-012178	Blumeria graminis	27.93	8.00e-30	124.00
IUUC-Bta-012976	Bos taurus	75.79	0.00e+00	627.00
IUUC-Bci-013680	Botrytis cinerea	28.65	1.00e-15	78.20
IUUC-Cja-019453	Callithrix jacchus	80.94	0.00e+00	719.00
IUUC-Cpo-021950	Cavia porcellus	73.91	0.00e+00	640.00
IUUC-Csa-023997	Chlorocebus sabaeus	82.28	0.00e+00	714.00
IUUC-Cho-024771	Choloepus hoffmanni	79.90	1.00e-91	330.00
IUUC-Cgl-026668	Colletotrichum gloeosporioides	26.86	2.00e-16	80.10
IUUC-Cme-027202	Cyanidioschyzon merolae	31.76	3.00e-12	66.20
IUUC-Dre-028479	Danio rerio	45.83	4.00e-72	265.00
IUUC-Dno-028943	Dasypus novemcinctus	80.52	0.00e+00	704.00
IUUC-Dor-031046	Dipodomys ordii	68.71	3.00e-136	478.00
IUUC-Dse-031235	Dothistroma septosporum	30.77	2.00e-15	77.00
IUUC-Ete-032503	Echinops telfairi	65.37	5.00e-137	480.00
IUUC-Eca-033725	Equus caballus	87.08	0.00e+00	760.00
IUUC-Eeu-034573	Erinaceus europaeus	71.74	3.00e-119	422.00
IUUC-Fca-036495	Felis catus	82.84	0.00e+00	729.00
IUUC-Fal-036791	Ficedula albicollis	53.11	3.00e-92	332.00
IUUC-Fox-037868	Fusarium oxysporum	36.90	6.00e-13	68.60
IUUC-Fso-038144	Fusarium solani	30.95	6.00e-16	78.20
IUUC-Gmo-039152	Gadus morhua	46.39	7.00e-67	247.00
IUUC-Ggr-039737	Gaeumannomyces graminis	26.47	2.00e-15	77.40
IUUC-Gga-040788	Gallus gallus	54.45	4.00e-103	368.00
IUUC-Gac-041993	Gasterosteus aculeatus	43.68	5.00e-79	288.00
IUUC-Ggo-044889	Gorilla gorilla	82.05	0.00e+00	703.00
IUUC-Hsa-045957	Homo sapiens	82.54	0.00e+00	712.00
IUUC-Itr-048998	Ictidomys tridecemlineatus	79.41	0.00e+00	704.00
IUUC-Kpa-049300	Komagataella pastoris	34.67	8.00e-08	51.20
IUUC-Lch-050172	Latimeria chalumnae	53.27	7.00e-70	257.00
IUUC-Loc-052609	Lepisosteus oculatus	50.98	2.00e-85	309.00
IUUC-Laf-053889	Loxodonta africana	72.79	9.00e-163	566.00
IUUC-Mcc-055853	Macaca mulatta	82.54	0.00e+00	708.00
IUUC-Meu-056866	Macropus eugenii	54.36	5.00e-88	318.00
IUUC-Mor-057071	Magnaporthe oryzae	26.68	5.00e-30	125.00
IUUC-Mpo-057628	Magnaporthe poae	27.13	2.00e-14	73.60
IUUC-Mla-058953	Melampsora laricipopulina	24.22	5.00e-19	89.40
IUUC-Mga-059687	Meleagris gallopavo	50.24	3.00e-99	355.00
IUUC-Mvi-060412	Microbotryum violaceum	22.36	3.00e-11	63.50
IUUC-Mmr-061563	Microcebus murinus	81.35	0.00e+00	714.00
IUUC-Mdo-062655	Monodelphis domestica	61.63	8.00e-130	457.00
IUUC-Mmu-063647	Mus musculus	63.38	5.00e-157	547.00
IUUC-Mpu-065778	Mustela putorius furo	92.84	0.00e+00	852.00
IUUC-Mlu-068205	Myotis lucifugus	81.25	0.00e+00	669.00
IUUC-Nfi-068501	Neosartorya fischeri	28.87	7.00e-17	81.60
IUUC-Ncr-068917	Neurospora crassa	26.56	7.00e-31	128.00
IUUC-Nle-068990	Nomascus leucogenys	82.90	0.00e+00	719.00
IUUC-Opr-071146	Ochotona princeps	70.24	4.00e-168	584.00
IUUC-Ont-071835	Oreochromis niloticus	43.19	2.00e-73	269.00
IUUC-Oan-072827	Ornithorhynchus anatinus	40.51	1.00e-44	172.00
IUUC-Ocu-073986	Oryctolagus cuniculus	74.75	0.00e+00	642.00
IUUC-Ola-086997	Oryzias latipes	43.99	4.00e-66	244.00
IUUC-Olu-087771	Ostreococcus lucimarinus	32.00	1.00e-10	60.80
IUUC-Oga-088092	Otolemur garnettii	81.26	0.00e+00	740.00
IUUC-Oar-089651	Ovis aries	82.48	0.00e+00	691.00
IUUC-Ptr-091103	Pan troglodytes	82.74	0.00e+00	712.00
IUUC-Pan-092478	Papio anubis	81.89	0.00e+00	709.00
IUUC-Psi-093356	Pelodiscus sinensis	59.73	2.00e-114	405.00
IUUC-Pfo-096663	Poecilia formosa	41.69	6.00e-59	221.00
IUUC-Pab-098515	Pongo abelii	82.94	0.00e+00	714.00
IUUC-Pca-100588	Procavia capensis	62.93	7.00e-130	457.00
IUUC-Pva-102377	Pteropus vampyrus	83.50	0.00e+00	730.00
IUUC-Pgr-103556	Puccinia graminis	24.11	4.00e-15	76.30
IUUC-Pte-104362	Pyrenophora teres	26.54	1.00e-10	60.80
IUUC-Pyt-104823	Pyrenophora triticirepentis	27.37	1.00e-10	61.20
IUUC-Rno-105866	Rattus norvegicus	74.75	6.00e-176	610.00
IUUC-Sce-106454	Saccharomyces cerevisiae	37.33	2.00e-11	63.90
IUUC-Sha-107515	Sarcophilus harrisii	60.36	2.00e-127	449.00
IUUC-Sja-107689	Schizosaccharomyces japonicus	27.71	8.00e-14	71.60
IUUC-Spo-108248	Schizosaccharomyces pombe	26.02	4.00e-19	89.00
IUUC-Ssl-108430	Sclerotinia sclerotiorum	28.09	6.00e-15	75.50
IUUC-Sre-115123	Sporisorium reilianum	23.61	1.00e-12	67.80
IUUC-Ssc-115992	Sus scrofa	82.44	2.00e-165	575.00
IUUC-Tgu-117286	Taeniopygia guttata	53.83	6.00e-97	347.00
IUUC-Tru-117959	Takifugu rubripes	43.07	2.00e-69	256.00
IUUC-Tsy-119286	Tarsius syrichta	61.71	2.00e-138	485.00
IUUC-Tni-120570	Tetraodon nigroviridis	48.34	8.00e-73	266.00
IUUC-Tre-121893	Trichoderma reesei	25.82	1.00e-15	77.80
IUUC-Tvi-122405	Trichoderma virens	25.82	2.00e-26	113.00
IUUC-Tbe-127758	Tupaia belangeri	78.70	4.00e-85	308.00
IUUC-Ttr-128841	Tursiops truncatus	82.31	0.00e+00	701.00
IUUC-Vda-130021	Verticillium dahliae	32.48	5.00e-16	77.80
IUUC-Vpa-130169	Vicugna pacos	78.37	3.00e-163	568.00
IUUC-Xtr-132308	Xenopus tropicalis	52.96	2.00e-101	362.00
IUUC-Xma-133868	Xiphophorus maculatus	43.96	3.00e-66	245.00
IUUC-Yli-134474	Yarrowia lipolytica	30.67	3.00e-14	72.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence