iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049950

Ensembl Protein ID

ENSLACP00000020988.1

UniProt Accession

H3BGG7; H3BGG7_LATCH

Genbank Protein ID

ENSLACP00000020988

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01016486

Gene Name

KDM2B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000018441.1	ENSLACT00000021128.1	ENSLACP00000020988.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	9.40e-15	54.8	623	688
E3 adaptor/Cullin RING/SCF/F-box	9.60e-06	25.9	941	1030

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggede......k....slveCekCrewfHpaClkls.....veeelpnsekwiCpkCrsk 54
           +vClvCge+g+++      +    +l+eC++C+e++Hp+Clk++     v++elpn+  w+CpkC+++
   Q: 623  AVCLVCGEAGKEDtleeedDkfnvMLMECSICNEIIHPGCLKIKesdgvVNDELPNC--WECPKCNHA 688
           79*********9977766516789*********************************..*******85 PP

E3 adaptor/Cullin RING/SCF/F-box

   S: 55   srrtprqpprgpsaaakpkaglrseaaa.apap.apaptptpeegpdaglldrlpeeilveilklldkeellraarvcrrwqelasq 139
            r tp+   r ps +  p   ++ e     p p +p p   p    d g  + +  e+++ ++++l++++l+ + rvc++w++ + +
   Q: 941  LRSTPKVSTR-PSPSLSPPKCIQMERHViRPPPiSPPPDSLPL---DDGEAHVMRREVWMAVFSYLSHKDLCICMRVCKTWNRWCCD 1023
           3667777766.44444444455555444034331333444443...5666777888**************************55555 PP
   S: 140  kalwktv 146
           k+lw ++
   Q: 1024 KRLWTKI 1030
           99*9986 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MEAQKESGRR LRAICRRRYD ENEDLSDVEE IASIRSFNVE AKLESVSYNG NYVHFMEGKD 60
FTYEYVQREA LKYPLIFRNK DGLGIKMPDP DFGVKDVKLL VGSRRVVDVM DVNTQKGIEM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGCAC AGAAAGAATC TGGACGGAGA TTGGTGTGTA GTTTTTGTGT ATAATTCCTA 60
TGCTTTTTAT TTAGAAAATA GTCTGTGCAA TACTGAAGAC AATATAGATA TTTTAGGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001358	Ailuropoda melanoleuca	78.17	0.00e+00	1906.00
IUUC-Apl-003787	Anas platyrhynchos	85.39	0.00e+00	1948.00
IUUC-Aca-004247	Anolis carolinensis	74.12	0.00e+00	1724.00
IUUC-Ago-007912	Ashbya gossypii	39.66	1.00e-50	194.00
IUUC-Afu-008903	Aspergillus fumigatus	44.06	7.00e-64	239.00
IUUC-Ani-009279	Aspergillus nidulans	47.39	8.00e-64	239.00
IUUC-Ang-009645	Aspergillus niger	45.08	1.00e-60	228.00
IUUC-Ate-010345	Aspergillus terreus	46.59	2.00e-65	244.00
IUUC-Ame-011463	Astyanax mexicanus	75.00	5.00e-169	588.00
IUUC-Bta-013531	Bos taurus	78.67	0.00e+00	1899.00
IUUC-Cja-018876	Callithrix jacchus	75.82	0.00e+00	1798.00
IUUC-Cfa-020857	Canis familiaris	78.54	0.00e+00	1901.00
IUUC-Cpo-021967	Cavia porcellus	76.18	0.00e+00	1798.00
IUUC-Csa-023210	Chlorocebus sabaeus	77.98	0.00e+00	1867.00
IUUC-Cho-024541	Choloepus hoffmanni	45.23	5.00e-137	482.00
IUUC-Cin-025140	Ciona intestinalis	60.73	1.00e-105	377.00
IUUC-Csv-025861	Ciona savignyi	57.10	1.00e-115	410.00
IUUC-Cne-026797	Cryptococcus neoformans	37.88	9.00e-56	211.00
IUUC-Dre-028272	Danio rerio	65.23	0.00e+00	1588.00
IUUC-Dno-030034	Dasypus novemcinctus	77.77	0.00e+00	1870.00
IUUC-Dor-030736	Dipodomys ordii	69.40	0.00e+00	781.00
IUUC-Dse-031402	Dothistroma septosporum	44.87	1.00e-59	225.00
IUUC-Dme-032039	Drosophila melanogaster	58.28	2.00e-118	421.00
IUUC-Eca-034255	Equus caballus	79.30	0.00e+00	1843.00
IUUC-Eeu-035038	Erinaceus europaeus	78.89	0.00e+00	964.00
IUUC-Fca-035786	Felis catus	79.01	0.00e+00	1842.00
IUUC-Fal-037589	Ficedula albicollis	84.02	0.00e+00	2034.00
IUUC-Gmo-038932	Gadus morhua	53.56	0.00e+00	716.00
IUUC-Gga-041103	Gallus gallus	84.59	0.00e+00	1112.00
IUUC-Gac-041304	Gasterosteus aculeatus	61.31	0.00e+00	1529.00
IUUC-Ggo-044522	Gorilla gorilla	70.59	0.00e+00	1571.00
IUUC-Hsa-045877	Homo sapiens	78.93	0.00e+00	1894.00
IUUC-Itr-049003	Ictidomys tridecemlineatus	79.95	0.00e+00	1096.00
IUUC-Loc-051972	Lepisosteus oculatus	72.39	0.00e+00	1131.00
IUUC-Laf-053623	Loxodonta africana	77.62	0.00e+00	1849.00
IUUC-Mcc-054943	Macaca mulatta	78.23	0.00e+00	1877.00
IUUC-Meu-056259	Macropus eugenii	78.80	0.00e+00	1884.00
IUUC-Mga-059671	Meleagris gallopavo	82.97	0.00e+00	1969.00
IUUC-Mmr-061003	Microcebus murinus	78.11	0.00e+00	1885.00
IUUC-Mmu-063584	Mus musculus	77.57	0.00e+00	1905.00
IUUC-Mpu-066056	Mustela putorius furo	78.54	0.00e+00	1893.00
IUUC-Mlu-067850	Myotis lucifugus	78.70	0.00e+00	1896.00
IUUC-Nfi-068537	Neosartorya fischeri	45.45	1.00e-63	238.00
IUUC-Nle-069837	Nomascus leucogenys	81.41	0.00e+00	1742.00
IUUC-Opr-070943	Ochotona princeps	75.68	0.00e+00	1751.00
IUUC-Ont-071663	Oreochromis niloticus	66.54	0.00e+00	1608.00
IUUC-Oan-072934	Ornithorhynchus anatinus	72.08	0.00e+00	1163.00
IUUC-Ocu-074706	Oryctolagus cuniculus	78.64	0.00e+00	1892.00
IUUC-Ola-086543	Oryzias latipes	63.82	0.00e+00	1566.00
IUUC-Oga-088671	Otolemur garnettii	71.94	0.00e+00	881.00
IUUC-Oar-089560	Ovis aries	74.81	0.00e+00	1825.00
IUUC-Ptr-090875	Pan troglodytes	79.09	0.00e+00	1905.00
IUUC-Pan-091788	Papio anubis	76.91	0.00e+00	1837.00
IUUC-Psi-093382	Pelodiscus sinensis	84.87	0.00e+00	2053.00
IUUC-Pma-094687	Petromyzon marinus	51.46	1.00e-98	353.00
IUUC-Ppa-095609	Physcomitrella patens	42.06	6.00e-57	214.00
IUUC-Pfo-096272	Poecilia formosa	66.51	0.00e+00	1561.00
IUUC-Pab-097907	Pongo abelii	74.67	0.00e+00	1747.00
IUUC-Pca-100628	Procavia capensis	71.23	0.00e+00	1543.00
IUUC-Pva-102956	Pteropus vampyrus	71.60	0.00e+00	865.00
IUUC-Pgr-103554	Puccinia graminis	44.33	1.00e-72	267.00
IUUC-Rno-105722	Rattus norvegicus	77.63	0.00e+00	1503.00
IUUC-Sce-106445	Saccharomyces cerevisiae	44.10	5.00e-47	181.00
IUUC-Sha-106626	Sarcophilus harrisii	74.79	0.00e+00	1702.00
IUUC-Smo-109024	Selaginella moellendorffii	40.23	1.00e-57	217.00
IUUC-Sre-115112	Sporisorium reilianum	38.78	9.00e-57	214.00
IUUC-Ssc-115918	Sus scrofa	77.18	0.00e+00	1446.00
IUUC-Tgu-117229	Taeniopygia guttata	72.23	0.00e+00	1728.00
IUUC-Tru-118638	Takifugu rubripes	63.74	0.00e+00	987.00
IUUC-Tni-120020	Tetraodon nigroviridis	51.39	0.00e+00	655.00
IUUC-Tme-127054	Tuber melanosporum	41.20	2.00e-53	204.00
IUUC-Tbe-127654	Tupaia belangeri	72.42	0.00e+00	1016.00
IUUC-Ttr-128821	Tursiops truncatus	71.84	0.00e+00	1674.00
IUUC-Uma-129458	Ustilago maydis	38.76	4.00e-57	216.00
IUUC-Vpa-130655	Vicugna pacos	56.15	0.00e+00	707.00
IUUC-Xtr-131823	Xenopus tropicalis	72.78	0.00e+00	1755.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence