iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074875

Ensembl Protein ID

ENSOCUP00000003371.2

UniProt Accession

G1SKM5; G1SKM5_RABIT

Protein Name

Uncharacterized protein

Gene Name

NPLOC4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000003888.3	ENSOCUT00000003886.3	ENSOCUP00000003371.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	5.70e-12	45.0	581	607

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 2    eaqWaCsaCTflNePeavkCemCsrpR 28
           +a+WaC++CTf+N P +++CemCs pR
   Q: 581  AAMWACQHCTFMNPPGTGHCEMCSLPR 607
           689***********************9 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

FHLQQIIRVQ SPDGVKRITA TKRETAATFL KKVAKEFGFQ NNGFSVYINR NKTGEITASS 60
NKSLSLLRIK HGDLLFLFPS SLAGPSSEME TSTTLGLKAL GSAHVVEDEI DQYLSRQDGK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCATCTGC AACAGATAAT CCGCGTCCAG TCCCCGGATG GCGTGAAGCG GATCACCGCG 60
ACCAAGAGAG AAACAGCTGC GACGTTTCTG AAAAAGGTAC CGCGGCGCGG CCTTCCCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR016563--Npl4
IPR007717--NPL4_C
IPR024682--Npl4_Ub-like_dom
IPR007716--NPL4_Zn-bd_put
IPR029071--Ubiquitin-rel_dom
IPR001876--Znf_RanBP2

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2

Pfam

PF05021--NPL4
PF11543--UN_NPL4
PF05020--zf-NPL4

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0005634--C:nucleus
GO:0036501--C:UFD1-NPL4 complex
GO:0034098--C:VCP-NPL4-UFD1 AAA ATPase complex
GO:0008270--F:zinc ion binding
GO:0039536--P:negative regulation of RIG-I signaling pathway
GO:0032480--P:negative regulation of type I interferon production
GO:0030970--P:retrograde protein transport, ER to cytosol
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000460	Aegilops tauschii	27.31	1.00e-14	73.90
IUUC-Aml-002268	Ailuropoda melanoleuca	92.05	0.00e+00	1117.00
IUUC-Atr-002939	Amborella trichopoda	28.04	1.00e-18	87.00
IUUC-Apl-003496	Anas platyrhynchos	83.93	0.00e+00	1004.00
IUUC-Aca-005230	Anolis carolinensis	85.48	0.00e+00	1074.00
IUUC-Aly-006056	Arabidopsis lyrata	29.53	7.00e-22	98.20
IUUC-Ath-006993	Arabidopsis thaliana	27.27	3.00e-20	92.40
IUUC-Ago-007954	Ashbya gossypii	35.06	2.00e-71	263.00
IUUC-Acl-008208	Aspergillus clavatus	32.01	2.00e-77	283.00
IUUC-Afl-008574	Aspergillus flavus	34.30	2.00e-75	276.00
IUUC-Afu-008825	Aspergillus fumigatus	33.06	1.00e-83	303.00
IUUC-Ani-009495	Aspergillus nidulans	38.30	8.00e-84	304.00
IUUC-Ang-009762	Aspergillus niger	31.44	2.00e-74	273.00
IUUC-Aor-010199	Aspergillus oryzae	39.29	7.00e-74	271.00
IUUC-Ate-010592	Aspergillus terreus	34.94	3.00e-79	288.00
IUUC-Ame-011587	Astyanax mexicanus	62.80	9.00e-80	291.00
IUUC-Bgr-012124	Blumeria graminis	31.49	1.00e-77	284.00
IUUC-Bta-013312	Bos taurus	92.05	0.00e+00	1147.00
IUUC-Bci-013648	Botrytis cinerea	33.22	8.00e-85	308.00
IUUC-Bdi-014326	Brachypodium distachyon	28.00	2.00e-15	76.30
IUUC-Bol-016294	Brassica oleracea	27.86	6.00e-20	91.70
IUUC-Bra-017023	Brassica rapa	28.62	5.00e-20	92.00
IUUC-Cel-018713	Caenorhabditis elegans	41.81	9.00e-121	427.00
IUUC-Cja-018869	Callithrix jacchus	91.23	0.00e+00	1118.00
IUUC-Cfa-020757	Canis familiaris	92.38	0.00e+00	1131.00
IUUC-Cpo-022390	Cavia porcellus	92.28	0.00e+00	1129.00
IUUC-Csa-023366	Chlorocebus sabaeus	91.72	0.00e+00	1148.00
IUUC-Cho-024455	Choloepus hoffmanni	95.25	0.00e+00	747.00
IUUC-Cin-025638	Ciona intestinalis	46.85	2.00e-137	482.00
IUUC-Csv-026310	Ciona savignyi	42.31	8.00e-125	440.00
IUUC-Cgl-026685	Colletotrichum gloeosporioides	32.03	1.00e-79	290.00
IUUC-Cne-026794	Cryptococcus neoformans	28.74	9.00e-64	238.00
IUUC-Cme-027248	Cyanidioschyzon merolae	26.58	3.00e-15	76.60
IUUC-Dre-027689	Danio rerio	76.44	0.00e+00	961.00
IUUC-Dno-030004	Dasypus novemcinctus	91.23	0.00e+00	1126.00
IUUC-Dor-030585	Dipodomys ordii	90.59	0.00e+00	900.00
IUUC-Dse-031202	Dothistroma septosporum	31.88	2.00e-79	290.00
IUUC-Dme-032092	Drosophila melanogaster	46.57	3.00e-164	572.00
IUUC-Ete-033009	Echinops telfairi	96.53	1.00e-99	356.00
IUUC-Eca-034001	Equus caballus	92.38	0.00e+00	1152.00
IUUC-Eeu-034485	Erinaceus europaeus	76.47	0.00e+00	761.00
IUUC-Fca-036128	Felis catus	91.89	0.00e+00	1090.00
IUUC-Fal-037523	Ficedula albicollis	85.81	0.00e+00	1077.00
IUUC-Fox-037802	Fusarium oxysporum	32.44	7.00e-85	308.00
IUUC-Fso-038152	Fusarium solani	31.99	2.00e-84	306.00
IUUC-Gmo-038486	Gadus morhua	70.96	0.00e+00	876.00
IUUC-Ggr-039916	Gaeumannomyces graminis	36.48	3.00e-76	279.00
IUUC-Gga-041208	Gallus gallus	87.27	0.00e+00	1096.00
IUUC-Gac-042304	Gasterosteus aculeatus	74.19	0.00e+00	903.00
IUUC-Gma-044178	Glycine max	26.62	2.00e-15	76.60
IUUC-Ggo-045236	Gorilla gorilla	88.18	0.00e+00	1097.00
IUUC-Hsa-046334	Homo sapiens	91.56	0.00e+00	1144.00
IUUC-Hvu-047323	Hordeum vulgare	26.24	3.00e-08	51.60
IUUC-Itr-047878	Ictidomys tridecemlineatus	89.22	0.00e+00	648.00
IUUC-Lch-050302	Latimeria chalumnae	79.77	0.00e+00	1008.00
IUUC-Lpe-051362	Leersia perrieri	28.21	2.00e-17	83.20
IUUC-Loc-052548	Lepisosteus oculatus	78.37	0.00e+00	941.00
IUUC-Lma-053092	Leptosphaeria maculans	32.67	3.00e-85	309.00
IUUC-Laf-053911	Loxodonta africana	91.74	0.00e+00	1143.00
IUUC-Mcc-055830	Macaca mulatta	91.10	0.00e+00	1135.00
IUUC-Meu-056460	Macropus eugenii	57.91	7.00e-147	513.00
IUUC-Mor-057189	Magnaporthe oryzae	35.77	4.00e-79	288.00
IUUC-Mpo-057366	Magnaporthe poae	36.58	2.00e-75	276.00
IUUC-Mtr-057834	Medicago truncatula	26.47	6.00e-17	81.60
IUUC-Mla-059190	Melampsora laricipopulina	30.95	1.00e-74	274.00
IUUC-Mga-060036	Meleagris gallopavo	86.96	0.00e+00	1093.00
IUUC-Mvi-060275	Microbotryum violaceum	33.65	5.00e-71	262.00
IUUC-Mmr-061300	Microcebus murinus	91.95	0.00e+00	1154.00
IUUC-Mdo-062911	Monodelphis domestica	90.37	0.00e+00	966.00
IUUC-Mmu-063916	Mus musculus	92.22	0.00e+00	1128.00
IUUC-Mac-065601	Musa acuminata	32.35	2.00e-11	63.50
IUUC-Mpu-065912	Mustela putorius furo	91.56	0.00e+00	1120.00
IUUC-Mlu-067965	Myotis lucifugus	91.23	0.00e+00	1112.00
IUUC-Nfi-068465	Neosartorya fischeri	33.22	2.00e-84	306.00
IUUC-Ncr-068936	Neurospora crassa	32.89	2.00e-81	296.00
IUUC-Nle-069570	Nomascus leucogenys	91.23	0.00e+00	1138.00
IUUC-Opr-071097	Ochotona princeps	86.09	0.00e+00	843.00
IUUC-Ont-071430	Oreochromis niloticus	76.40	0.00e+00	951.00
IUUC-Oan-073709	Ornithorhynchus anatinus	76.80	0.00e+00	711.00
IUUC-Oba-075214	Oryza barthii	27.47	2.00e-17	83.20
IUUC-Obr-076758	Oryza brachyantha	28.04	3.00e-17	82.00
IUUC-Ogl-077665	Oryza glaberrima	27.47	2.00e-17	83.20
IUUC-Ogu-078899	Oryza glumaepatula	27.47	2.00e-17	83.20
IUUC-Oin-079167	Oryza indica	27.47	2.00e-17	83.20
IUUC-Olo-080451	Oryza longistaminata	27.47	2.00e-17	82.80
IUUC-Ome-081836	Oryza meridionalis	27.84	2.00e-17	83.20
IUUC-Oni-083019	Oryza nivara	27.47	2.00e-17	83.20
IUUC-Opu-083122	Oryza punctata	28.04	1.00e-17	84.30
IUUC-Oru-084900	Oryza rufipogon	27.47	2.00e-17	83.20
IUUC-Osa-086054	Oryza sativa	27.47	2.00e-17	83.20
IUUC-Ola-087077	Oryzias latipes	64.96	0.00e+00	773.00
IUUC-Olu-087601	Ostreococcus lucimarinus	26.43	1.00e-05	44.30
IUUC-Oga-088049	Otolemur garnettii	78.88	0.00e+00	967.00
IUUC-Oar-089678	Ovis aries	92.05	0.00e+00	1147.00
IUUC-Ptr-091380	Pan troglodytes	88.77	0.00e+00	1044.00
IUUC-Pan-092821	Papio anubis	90.12	0.00e+00	1132.00
IUUC-Psi-093074	Pelodiscus sinensis	87.13	0.00e+00	1083.00
IUUC-Pma-094102	Petromyzon marinus	65.67	0.00e+00	832.00
IUUC-Pno-094987	Phaeosphaeria nodorum	32.89	7.00e-85	308.00
IUUC-Ppa-095368	Physcomitrella patens	27.68	9.00e-18	84.30
IUUC-Pfo-097245	Poecilia formosa	76.48	0.00e+00	917.00
IUUC-Pab-098763	Pongo abelii	91.79	0.00e+00	1155.00
IUUC-Pop-099355	Populus trichocarpa	30.26	2.00e-14	73.20
IUUC-Ppe-101990	Prunus persica	27.85	1.00e-17	84.00
IUUC-Pva-102308	Pteropus vampyrus	83.30	0.00e+00	882.00
IUUC-Pgr-103553	Puccinia graminis	31.42	4.00e-73	269.00
IUUC-Pte-104100	Pyrenophora teres	31.67	2.00e-80	293.00
IUUC-Pyt-104482	Pyrenophora triticirepentis	35.85	5.00e-82	298.00
IUUC-Rno-105582	Rattus norvegicus	92.22	0.00e+00	1129.00
IUUC-Sce-106145	Saccharomyces cerevisiae	32.31	2.00e-83	303.00
IUUC-Sha-106647	Sarcophilus harrisii	89.88	0.00e+00	1105.00
IUUC-Sja-107972	Schizosaccharomyces japonicus	33.58	5.00e-78	285.00
IUUC-Spo-108281	Schizosaccharomyces pombe	32.29	5.00e-80	291.00
IUUC-Ssl-108617	Sclerotinia sclerotiorum	37.64	2.00e-80	293.00
IUUC-Smo-108933	Selaginella moellendorffii	29.79	8.00e-19	88.20
IUUC-Sit-110083	Setaria italica	28.47	4.00e-16	79.00
IUUC-Sly-111645	Solanum lycopersicum	25.67	2.00e-16	79.70
IUUC-Stu-112422	Solanum tuberosum	25.67	2.00e-16	80.10
IUUC-Sbi-113987	Sorghum bicolor	29.71	1.00e-16	80.90
IUUC-Sre-115095	Sporisorium reilianum	35.91	2.00e-69	257.00
IUUC-Ssc-116141	Sus scrofa	90.37	0.00e+00	1012.00
IUUC-Tgu-117492	Taeniopygia guttata	84.04	0.00e+00	780.00
IUUC-Tru-118463	Takifugu rubripes	74.32	0.00e+00	900.00
IUUC-Tsy-118993	Tarsius syrichta	82.89	0.00e+00	920.00
IUUC-Tni-119896	Tetraodon nigroviridis	76.07	0.00e+00	908.00
IUUC-Tca-121169	Theobroma cacao	27.80	1.00e-19	90.50
IUUC-Tre-122046	Trichoderma reesei	31.67	1.00e-79	290.00
IUUC-Tvi-122415	Trichoderma virens	32.39	3.00e-81	296.00
IUUC-Tae-123514	Triticum aestivum	27.31	8.00e-15	74.70
IUUC-Tme-127123	Tuber melanosporum	35.13	6.00e-91	328.00
IUUC-Tbe-127629	Tupaia belangeri	86.23	1.00e-141	496.00
IUUC-Ttr-128476	Tursiops truncatus	84.09	0.00e+00	931.00
IUUC-Uma-129492	Ustilago maydis	33.90	4.00e-72	265.00
IUUC-Vda-129702	Verticillium dahliae	32.45	1.00e-78	287.00
IUUC-Vvi-131090	Vitis vinifera	27.13	4.00e-14	72.40
IUUC-Xtr-131786	Xenopus tropicalis	81.15	0.00e+00	991.00
IUUC-Xma-133997	Xiphophorus maculatus	73.93	0.00e+00	909.00
IUUC-Yli-134537	Yarrowia lipolytica	34.57	4.00e-84	305.00
IUUC-Zma-134847	Zea mays	29.02	7.00e-18	85.10

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence