iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-042088

UUCD1 version

UUC-GaA-00462

Ensembl Protein ID

ENSGACP00000012130.1

UniProt Accession

G3P3F7; G3P3F7_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000009166.1	ENSGACT00000012154.1	ENSGACP00000012130.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	3.80e-113	378.7	708	1071

Active Site

Position(s)	Description	Evidence
1039	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdg 85
           ++k +++v+fv+     E+g+d++Gv++efl++++k+++np l+lf+++++++  l+p+p+s++++ +hl+lFef+G++lgka+++g
   Q: 708  SIKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKKVFNPALNLFKTTSGNE-RLYPSPTSYIHE-NHLQLFEFVGKMLGKAMYEG 792
           67899*****************************************9888655.569*******76.******************** PP
   S: 86   rlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtn 167
            ++d+p++++f++++lg+       s+++l+++d+e+yk+l++ik++ + di +lgl l+++  e+++g+  ++eL+pgG+++pVtn
   Q: 793  IVVDVPFASFFLSQVLGHhhstfYSSIDELPSLDSEFYKNLTSIKRY-DGDIGDLGLSLSYD--EDVMGQLVCHELIPGGKTMPVTN 876
           ******************777777999********************.78999998888875..889******************** PP
   S: 168  eNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevl 253
           eNk +Y++l++++r++++ikeq++af +Gf+++i+ e+l +F++ e++ li+G+ +eid++dlkk+t y gg+++++++i+w+w++l
   Q: 877  ENKISYIHLMAHFRMHTQIKEQTAAFIRGFRSIINSEWLHMFSTPEVQRLISGDnAEIDLDDLKKHTVYYGGFHSSHRVIIWLWDIL 963
           ******************************************************9******************************** PP
   S: 254  .eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeYss 315
            ++f+s+er++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Ys+
   Q: 964  sSDFTSDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNYSK 1050
           999************************************************************9999******************** PP
   S: 316  keilkekLlyAieetkgFels 336
           k+il++kL+yAi++++gFels
   Q: 1051 KSILRDKLRYAISMNTGFELS 1071
           ******************985 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MFSIPQSSKS EFLDKARQAR EERRGQKDKE KSAILIQALV RRFLCRCRLQ KQIRKEVDDY 60
FQASETGTSK RNALSIFKIT RKLLFVYRLE DKMMAQRFEK LCRAILASME VENEPKVWYV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTAGTA TACCGCAAAG CTCCAAGTCC GAGTTCCTGG ACAAAGCCAG GCAGGCCAGG 60
GAGGAAAGGA GAGGACAGAA GGACAAGGAG AAGTCAGCAA TCCTCATCCA AGCCCTGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.25	2.00e-105	377.00
IUUC-Aml-002107	Ailuropoda melanoleuca	80.97	0.00e+00	1786.00
IUUC-Atr-003017	Amborella trichopoda	39.36	1.00e-112	401.00
IUUC-Apl-003328	Anas platyrhynchos	84.27	0.00e+00	1769.00
IUUC-Aly-005794	Arabidopsis lyrata	39.29	1.00e-107	384.00
IUUC-Ath-007269	Arabidopsis thaliana	39.82	5.00e-111	395.00
IUUC-Ago-007748	Ashbya gossypii	35.17	1.00e-63	238.00
IUUC-Acl-008158	Aspergillus clavatus	32.05	1.00e-59	225.00
IUUC-Afl-008398	Aspergillus flavus	33.20	1.00e-63	238.00
IUUC-Afu-008937	Aspergillus fumigatus	32.11	6.00e-62	233.00
IUUC-Ani-009252	Aspergillus nidulans	32.72	3.00e-67	250.00
IUUC-Ang-009773	Aspergillus niger	30.41	5.00e-66	246.00
IUUC-Aor-009940	Aspergillus oryzae	33.20	1.00e-63	238.00
IUUC-Ate-010395	Aspergillus terreus	32.66	5.00e-65	243.00
IUUC-Bgr-012269	Blumeria graminis	34.50	2.00e-60	226.00
IUUC-Bta-013547	Bos taurus	80.60	0.00e+00	1805.00
IUUC-Bci-013743	Botrytis cinerea	34.76	8.00e-70	259.00
IUUC-Bdi-014502	Brachypodium distachyon	39.15	2.00e-109	390.00
IUUC-Bol-015093	Brassica oleracea	40.00	2.00e-111	397.00
IUUC-Bra-016722	Brassica rapa	40.18	2.00e-112	400.00
IUUC-Cel-018447	Caenorhabditis elegans	38.97	0.00e+00	675.00
IUUC-Cja-019855	Callithrix jacchus	80.50	0.00e+00	1783.00
IUUC-Cfa-020066	Canis familiaris	81.15	0.00e+00	1769.00
IUUC-Cpo-021504	Cavia porcellus	81.08	0.00e+00	1816.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	34.99	5.00e-74	273.00
IUUC-Csa-023579	Chlorocebus sabaeus	80.88	0.00e+00	1786.00
IUUC-Cho-024430	Choloepus hoffmanni	70.21	0.00e+00	1280.00
IUUC-Cin-025750	Ciona intestinalis	45.65	0.00e+00	954.00
IUUC-Csv-026016	Ciona savignyi	47.02	0.00e+00	1007.00
IUUC-Cgl-026559	Colletotrichum gloeosporioides	35.00	1.00e-73	271.00
IUUC-Cne-026841	Cryptococcus neoformans	37.67	2.00e-71	264.00
IUUC-Cme-027265	Cyanidioschyzon merolae	40.13	2.00e-90	327.00
IUUC-Dre-028271	Danio rerio	90.11	0.00e+00	1923.00
IUUC-Dno-029054	Dasypus novemcinctus	81.72	0.00e+00	1806.00
IUUC-Dor-030938	Dipodomys ordii	85.47	0.00e+00	1105.00
IUUC-Dse-031416	Dothistroma septosporum	33.40	4.00e-64	240.00
IUUC-Dme-031602	Drosophila melanogaster	47.89	0.00e+00	969.00
IUUC-Ete-033041	Echinops telfairi	65.21	0.00e+00	1173.00
IUUC-Eca-034411	Equus caballus	81.44	0.00e+00	1775.00
IUUC-Eeu-035201	Erinaceus europaeus	76.72	0.00e+00	744.00
IUUC-Fca-036594	Felis catus	79.94	0.00e+00	1751.00
IUUC-Fal-037317	Ficedula albicollis	80.86	0.00e+00	1796.00
IUUC-Fox-037788	Fusarium oxysporum	33.90	5.00e-76	279.00
IUUC-Fso-038088	Fusarium solani	35.26	6.00e-75	276.00
IUUC-Gmo-039412	Gadus morhua	89.94	0.00e+00	1975.00
IUUC-Ggr-039941	Gaeumannomyces graminis	35.21	7.00e-73	269.00
IUUC-Gga-040149	Gallus gallus	84.62	0.00e+00	1822.00
IUUC-Gma-043839	Glycine max	40.14	3.00e-111	396.00
IUUC-Ggo-045279	Gorilla gorilla	80.69	0.00e+00	1782.00
IUUC-Hsa-045660	Homo sapiens	80.50	0.00e+00	1778.00
IUUC-Hvu-047770	Hordeum vulgare	37.85	1.00e-110	393.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	72.60	0.00e+00	839.00
IUUC-Kpa-049307	Komagataella pastoris	31.70	8.00e-66	245.00
IUUC-Lch-050664	Latimeria chalumnae	85.65	0.00e+00	1889.00
IUUC-Lpe-050755	Leersia perrieri	37.12	3.00e-98	353.00
IUUC-Loc-052791	Lepisosteus oculatus	90.59	0.00e+00	1937.00
IUUC-Lma-053096	Leptosphaeria maculans	34.70	2.00e-67	251.00
IUUC-Laf-053902	Loxodonta africana	81.62	0.00e+00	1803.00
IUUC-Mcc-054730	Macaca mulatta	80.78	0.00e+00	1785.00
IUUC-Meu-056527	Macropus eugenii	76.65	0.00e+00	1628.00
IUUC-Mor-057021	Magnaporthe oryzae	35.17	1.00e-61	232.00
IUUC-Mpo-057570	Magnaporthe poae	35.97	1.00e-69	258.00
IUUC-Mtr-057671	Medicago truncatula	39.79	4.00e-110	392.00
IUUC-Mla-059124	Melampsora laricipopulina	38.75	5.00e-78	285.00
IUUC-Mga-059260	Meleagris gallopavo	84.28	0.00e+00	1817.00
IUUC-Mvi-060445	Microbotryum violaceum	33.33	6.00e-78	286.00
IUUC-Mmr-060804	Microcebus murinus	80.02	0.00e+00	1744.00
IUUC-Mdo-062575	Monodelphis domestica	80.26	0.00e+00	1722.00
IUUC-Mmu-063636	Mus musculus	79.48	0.00e+00	1717.00
IUUC-Mac-065275	Musa acuminata	35.98	1.00e-108	387.00
IUUC-Mpu-066677	Mustela putorius furo	80.08	0.00e+00	1665.00
IUUC-Mlu-067952	Myotis lucifugus	81.42	0.00e+00	1743.00
IUUC-Nfi-068280	Neosartorya fischeri	32.32	2.00e-62	234.00
IUUC-Ncr-068869	Neurospora crassa	32.53	4.00e-70	259.00
IUUC-Nle-069153	Nomascus leucogenys	80.60	0.00e+00	1780.00
IUUC-Opr-070554	Ochotona princeps	81.41	0.00e+00	1643.00
IUUC-Ont-071372	Oreochromis niloticus	95.33	0.00e+00	2038.00
IUUC-Oan-073327	Ornithorhynchus anatinus	69.89	0.00e+00	736.00
IUUC-Ocu-074183	Oryctolagus cuniculus	79.76	0.00e+00	1768.00
IUUC-Oba-075006	Oryza barthii	37.82	4.00e-112	399.00
IUUC-Obr-076133	Oryza brachyantha	37.01	7.00e-112	399.00
IUUC-Ogl-077003	Oryza glaberrima	37.54	3.00e-112	399.00
IUUC-Ogu-078947	Oryza glumaepatula	37.79	5.00e-113	402.00
IUUC-Oin-080058	Oryza indica	39.09	4.00e-108	386.00
IUUC-Olo-080475	Oryza longistaminata	37.95	1.00e-112	401.00
IUUC-Ome-081741	Oryza meridionalis	38.69	6.00e-101	362.00
IUUC-Oni-082385	Oryza nivara	37.79	5.00e-113	402.00
IUUC-Opu-083176	Oryza punctata	38.27	8.00e-112	398.00
IUUC-Oru-084554	Oryza rufipogon	35.86	1.00e-99	358.00
IUUC-Osa-085355	Oryza sativa	37.95	8.00e-113	401.00
IUUC-Ola-087337	Oryzias latipes	94.02	0.00e+00	1962.00
IUUC-Olu-087699	Ostreococcus lucimarinus	40.51	7.00e-78	283.00
IUUC-Oga-088342	Otolemur garnettii	79.68	0.00e+00	1705.00
IUUC-Oar-090234	Ovis aries	80.21	0.00e+00	1779.00
IUUC-Ptr-091661	Pan troglodytes	80.69	0.00e+00	1782.00
IUUC-Pan-092728	Papio anubis	80.62	0.00e+00	1780.00
IUUC-Psi-093251	Pelodiscus sinensis	84.06	0.00e+00	1686.00
IUUC-Pma-094195	Petromyzon marinus	70.05	0.00e+00	1454.00
IUUC-Pno-095132	Phaeosphaeria nodorum	33.33	4.00e-51	196.00
IUUC-Ppa-095544	Physcomitrella patens	37.87	1.00e-110	395.00
IUUC-Pfo-097472	Poecilia formosa	96.36	0.00e+00	2061.00
IUUC-Pab-098570	Pongo abelii	80.88	0.00e+00	1782.00
IUUC-Pop-098928	Populus trichocarpa	34.96	6.00e-97	348.00
IUUC-Pca-100110	Procavia capensis	70.62	0.00e+00	1493.00
IUUC-Ppe-101281	Prunus persica	39.18	3.00e-106	380.00
IUUC-Pva-102887	Pteropus vampyrus	76.51	0.00e+00	1651.00
IUUC-Pgr-103513	Puccinia graminis	38.05	9.00e-76	278.00
IUUC-Ptt-103967	Puccinia triticina	35.73	8.00e-66	245.00
IUUC-Pte-104105	Pyrenophora teres	34.16	3.00e-68	254.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	34.16	3.00e-68	254.00
IUUC-Rno-106028	Rattus norvegicus	77.07	0.00e+00	1633.00
IUUC-Sce-106446	Saccharomyces cerevisiae	34.76	3.00e-54	206.00
IUUC-Sha-107331	Sarcophilus harrisii	81.21	0.00e+00	1755.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	39.44	1.00e-82	301.00
IUUC-Spo-108097	Schizosaccharomyces pombe	34.01	6.00e-82	299.00
IUUC-Ssl-108520	Sclerotinia sclerotiorum	30.22	2.00e-69	257.00
IUUC-Smo-109488	Selaginella moellendorffii	37.61	5.00e-106	379.00
IUUC-Sit-109811	Setaria italica	39.25	5.00e-108	385.00
IUUC-Sly-111362	Solanum lycopersicum	34.78	9.00e-99	355.00
IUUC-Sar-113287	Sorex araneus	67.24	2.00e-160	560.00
IUUC-Sbi-113882	Sorghum bicolor	36.19	1.00e-102	368.00
IUUC-Sre-115038	Sporisorium reilianum	39.07	2.00e-81	297.00
IUUC-Ssc-116103	Sus scrofa	81.33	0.00e+00	1775.00
IUUC-Tgu-117275	Taeniopygia guttata	83.50	0.00e+00	1796.00
IUUC-Tru-118681	Takifugu rubripes	94.40	0.00e+00	2059.00
IUUC-Tsy-118985	Tarsius syrichta	71.01	0.00e+00	828.00
IUUC-Tni-120850	Tetraodon nigroviridis	98.25	0.00e+00	823.00
IUUC-Tca-121770	Theobroma cacao	39.54	1.00e-110	395.00
IUUC-Tre-121892	Trichoderma reesei	35.97	6.00e-77	282.00
IUUC-Tvi-122354	Trichoderma virens	36.40	7.00e-79	289.00
IUUC-Tae-125466	Triticum aestivum	37.13	1.00e-110	394.00
IUUC-Tur-126086	Triticum urartu	39.25	1.00e-104	375.00
IUUC-Tme-127102	Tuber melanosporum	30.92	6.00e-78	286.00
IUUC-Tbe-127461	Tupaia belangeri	76.84	0.00e+00	1628.00
IUUC-Ttr-129269	Tursiops truncatus	80.88	0.00e+00	1750.00
IUUC-Uma-129343	Ustilago maydis	39.30	6.00e-84	306.00
IUUC-Vda-129748	Verticillium dahliae	33.54	4.00e-63	236.00
IUUC-Vpa-130523	Vicugna pacos	72.19	4.00e-112	399.00
IUUC-Vvi-131524	Vitis vinifera	39.15	2.00e-108	387.00
IUUC-Xtr-132146	Xenopus tropicalis	82.23	0.00e+00	1824.00
IUUC-Xma-133526	Xiphophorus maculatus	95.80	0.00e+00	2051.00
IUUC-Yli-134496	Yarrowia lipolytica	34.65	7.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence