iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nfi-068464

Ensembl Protein ID

CADNFIAP00006688

UniProt Accession

A1DHW6; SCONB_NEOFI

Genbank Protein ID

EAW18973.1

Protein Name

Probable E3 ubiquitin ligase complex SCF subunit sconB; Sulfur controller B; Sulfur metabolite repression control protein B

Genbank Nucleotide ID

DS027696

Gene Name

NFIA_089300; sconB

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADNFIAG00006855	CADNFIAT00006855	CADNFIAP00006688

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.30e-55	182.0	398	434
UBD/Beta-Prp	1.60e-76	256.5	357	688

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvllk 37
           gH ++++cl+f+dt l+sGs D+t+kvW++rtg ++ 
   Q: 398  GHRSGIRCLQFDDTKLISGSMDHTLKVWNWRTGECIS 434
           8**********66*********************975 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           kg h++ i c++f  ++++latgs+d+tik+wd++tg  lr+l+gh +++++++f+++   l++gs D+t+kvw+ +tg+c++t++gh   v+
   Q: 357  KG-HSNGIMCLQF--EDNILATGSYDATIKIWDTETGEELRTLKGHRSGIRCLQFDDT--KLISGSMDHTLKVWNWRTGECISTYSGHRGGVV 444
           34.5556777***..*******************************************..6******************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls.... 187
            l+f++    l+sGs d+t+++w+ e ++    +l+gh+++vn v+v++ ++ ++s+s+D tv+lWdl t++++rt+ g h ++v+ +     
   Q: 445  GLHFDA--TILASGSVDKTVKIWNFEDKSTC--LLRGHTDWVNAVRVDSASRTVFSASDDCTVKLWDLDTKSCIRTFHG-HVGQVQQVVplpr 532
           ******..*****************999988..59*******************************************9.*********9999 PP
   S: 188  ......fdsng..................................................kelvsgsldgtvklwdlqtgecvrtlnghtdn 224
                                                                        +++v+ +ld+t++lw+ ++g+c+rt+ gh + 
   Q: 533  efefedH---DvecendnvsvtsgdspaaspqaipgfdaqtsdtpssafgpafddgrpsppRYIVTSALDSTIRLWETSSGRCLRTFFGHLEG 622
           9886550...24555555566666667777777777777789999999999999999************************************ PP
   S: 225  vksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
           v+ ++++  + r+vsg++D+ ++iWd r+g++ +t+++h     +v+++++gd+ +++gsed++v++++++
   Q: 623  VWALAAD--TLRIVSGAEDRMVKIWDPRTGKCERTFTGHS---GPVTCIGLGDSRFATGSEDCEVRMYSFQ 688
           **99999..*****************************88...55555666*****************996 PP

Organism

Neosartorya fischeri

Functional Description
(View)

Component of the SCF(sconB) E3 ubiquitin ligase complex involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor.

Protein Sequence
(Fasta)

MDAHELSFRD GHGSSTSTMK DECASEEKAL YLPGDSSFAS VFGPSETVED VETGPESTQD 60
KPHSFNTQKP IREKLAGKNV APFLARHIPE QYAPLGSQTG QPVEISSANS KYCYRHRPDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGCCC ATGAACTGTC GTTTCGCGAT GGTCACGGAT CCTCCACCTC GACTATGAAA 60
GACGAGTGTG CCTCGGAGGA GAAGGCGCTT TACCTCCCAG GAGATTCTTC CTTTGCATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR001810--F-box_dom
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50181--FBOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12937--F-box-like
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00256--FBOX
SM00320--WD40

Gene Ontology

GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:0071276--P:cellular response to cadmium ion
GO:0006270--P:DNA replication initiation
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030174--P:regulation of DNA-dependent DNA replication initiation
GO:0000083--P:regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0046685--P:response to arsenic-containing substance
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0006351--P:transcription, DNA-templated

KEGG

nfi:NFIA_089300

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007794	Ashbya gossypii	42.33	2.00e-134	471.00
IUUC-Acl-008078	Aspergillus clavatus	82.31	0.00e+00	1212.00
IUUC-Afl-008744	Aspergillus flavus	79.79	0.00e+00	1033.00
IUUC-Afu-008939	Aspergillus fumigatus	95.98	0.00e+00	1355.00
IUUC-Ani-009383	Aspergillus nidulans	75.94	0.00e+00	1033.00
IUUC-Ang-009570	Aspergillus niger	80.15	0.00e+00	1070.00
IUUC-Aor-010217	Aspergillus oryzae	81.00	0.00e+00	1017.00
IUUC-Ate-010336	Aspergillus terreus	80.09	0.00e+00	1065.00
IUUC-Bgr-012225	Blumeria graminis	56.84	0.00e+00	731.00
IUUC-Bci-013916	Botrytis cinerea	64.39	0.00e+00	824.00
IUUC-Cgl-026550	Colletotrichum gloeosporioides	52.96	0.00e+00	662.00
IUUC-Cne-026800	Cryptococcus neoformans	34.57	4.00e-116	410.00
IUUC-Dse-031413	Dothistroma septosporum	57.74	0.00e+00	699.00
IUUC-Fox-037683	Fusarium oxysporum	53.39	0.00e+00	668.00
IUUC-Fso-038092	Fusarium solani	57.37	0.00e+00	746.00
IUUC-Ggr-039842	Gaeumannomyces graminis	53.46	0.00e+00	703.00
IUUC-Kpa-049101	Komagataella pastoris	45.83	3.00e-160	556.00
IUUC-Lma-053200	Leptosphaeria maculans	55.87	0.00e+00	761.00
IUUC-Mor-057039	Magnaporthe oryzae	56.16	0.00e+00	696.00
IUUC-Mpo-057381	Magnaporthe poae	53.48	0.00e+00	690.00
IUUC-Mla-059099	Melampsora laricipopulina	40.23	1.00e-119	422.00
IUUC-Mvi-060426	Microbotryum violaceum	35.45	8.00e-86	310.00
IUUC-Ncr-068962	Neurospora crassa	51.50	0.00e+00	684.00
IUUC-Pno-095133	Phaeosphaeria nodorum	52.28	2.00e-162	563.00
IUUC-Pgr-103527	Puccinia graminis	40.66	8.00e-67	246.00
IUUC-Ptt-103819	Puccinia triticina	32.01	3.00e-54	204.00
IUUC-Pte-104035	Pyrenophora teres	55.83	0.00e+00	694.00
IUUC-Pyt-104799	Pyrenophora triticirepentis	56.04	0.00e+00	702.00
IUUC-Sce-106343	Saccharomyces cerevisiae	42.20	2.00e-139	487.00
IUUC-Sja-107945	Schizosaccharomyces japonicus	39.23	6.00e-119	419.00
IUUC-Spo-108115	Schizosaccharomyces pombe	40.04	9.00e-109	385.00
IUUC-Sre-115173	Sporisorium reilianum	40.00	1.00e-100	359.00
IUUC-Tre-122126	Trichoderma reesei	56.96	0.00e+00	736.00
IUUC-Tvi-122482	Trichoderma virens	57.50	0.00e+00	744.00
IUUC-Tme-127212	Tuber melanosporum	56.25	0.00e+00	727.00
IUUC-Uma-129406	Ustilago maydis	39.73	4.00e-99	354.00
IUUC-Vda-129799	Verticillium dahliae	55.24	0.00e+00	702.00
IUUC-Yli-134408	Yarrowia lipolytica	46.69	1.00e-167	581.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence