iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-053422

Ensembl Protein ID

ENSLAFP00000007038.3

UniProt Accession

G3T1Q4; G3T1Q4_LOXAF

Protein Name

Uncharacterized protein

Gene Name

AURKA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000008392.3	ENSLAFT00000008390.3	ENSLAFP00000007038.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	86.39	0.00e+00	708.00	IUUC-Hsa-046968

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MDKSKENCIS GPIKTTLPLG DGPKRVPVTQ PFPSQNPLSA SGGQAQRVLC PSNSSQSIPS 60
QAQKLVSSRK PVQSQKQKPL QITTVPRPVS RPPNNTPKGE QAQPPASGNN SGKELASKQK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAAGT CTAAGGAAAA CTGCATTTCA GGACCCATTA AGGTGATTGA ATAATATAAT 60
TGCAATCATG TCTCAAATGG AGATTGGTCC CCTATCTGGA ATTTATACCT TTATTTATTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR030616--Aur
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0043203--C:axon hillock
GO:0005829--C:cytosol
GO:0042585--C:germinal vesicle
GO:0072687--C:meiotic spindle
GO:0072686--C:mitotic spindle
GO:0048471--C:perinuclear region of cytoplasm
GO:0045120--C:pronucleus
GO:0005876--C:spindle microtubule
GO:0031616--C:spindle pole centrosome
GO:0005524--F:ATP binding
GO:0035174--F:histone serine kinase activity
GO:0009948--P:anterior/posterior axis specification
GO:0051642--P:centrosome localization
GO:0097421--P:liver regeneration
GO:0007100--P:mitotic centrosome separation
GO:0007052--P:mitotic spindle organization
GO:0043066--P:negative regulation of apoptotic process
GO:0032091--P:negative regulation of protein binding
GO:1990138--P:neuron projection extension
GO:1900195--P:positive regulation of oocyte maturation
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0071539--P:protein localization to centrosome
GO:0031647--P:regulation of protein stability
GO:0009611--P:response to wounding
GO:0007057--P:spindle assembly involved in female meiosis I

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000930	Aegilops tauschii	62.32	3.00e-102	364.00
IUUC-Aml-001426	Ailuropoda melanoleuca	89.15	0.00e+00	709.00
IUUC-Atr-002453	Amborella trichopoda	65.59	3.00e-106	377.00
IUUC-Apl-003626	Anas platyrhynchos	70.72	7.00e-154	536.00
IUUC-Aca-004602	Anolis carolinensis	67.88	4.00e-145	507.00
IUUC-Aly-005878	Arabidopsis lyrata	64.18	2.00e-103	368.00
IUUC-Ath-007117	Arabidopsis thaliana	64.93	4.00e-104	370.00
IUUC-Acl-008199	Aspergillus clavatus	55.76	1.00e-85	309.00
IUUC-Afl-008419	Aspergillus flavus	58.43	2.00e-84	306.00
IUUC-Afu-008751	Aspergillus fumigatus	58.82	6.00e-85	307.00
IUUC-Ani-009181	Aspergillus nidulans	54.83	2.00e-89	322.00
IUUC-Ang-009787	Aspergillus niger	55.64	1.00e-85	309.00
IUUC-Aor-009980	Aspergillus oryzae	58.43	2.00e-84	306.00
IUUC-Ate-010286	Aspergillus terreus	58.43	8.00e-85	306.00
IUUC-Ame-010849	Astyanax mexicanus	59.08	5.00e-129	454.00
IUUC-Bgr-012110	Blumeria graminis	57.71	4.00e-87	315.00
IUUC-Bta-013474	Bos taurus	86.14	0.00e+00	707.00
IUUC-Bci-013756	Botrytis cinerea	57.50	3.00e-92	332.00
IUUC-Bdi-014257	Brachypodium distachyon	63.16	3.00e-103	367.00
IUUC-Bol-016310	Brassica oleracea	63.00	3.00e-101	361.00
IUUC-Bra-017438	Brassica rapa	63.00	1.00e-102	365.00
IUUC-Cel-018157	Caenorhabditis elegans	59.29	5.00e-100	357.00
IUUC-Cja-019282	Callithrix jacchus	84.65	0.00e+00	674.00
IUUC-Cfa-020162	Canis familiaris	87.08	0.00e+00	695.00
IUUC-Cpo-021764	Cavia porcellus	81.82	0.00e+00	647.00
IUUC-Cre-022827	Chlamydomonas reinhardtii	66.04	1.00e-104	372.00
IUUC-Csa-023694	Chlorocebus sabaeus	85.64	0.00e+00	636.00
IUUC-Cho-024350	Choloepus hoffmanni	94.90	5.00e-109	386.00
IUUC-Cin-025542	Ciona intestinalis	72.41	9.00e-116	409.00
IUUC-Csv-025873	Ciona savignyi	66.21	3.00e-116	410.00
IUUC-Cgl-026632	Colletotrichum gloeosporioides	45.60	2.00e-80	292.00
IUUC-Cne-026928	Cryptococcus neoformans	60.59	4.00e-95	341.00
IUUC-Cme-027336	Cyanidioschyzon merolae	71.64	1.00e-117	416.00
IUUC-Dre-028198	Danio rerio	62.01	1.00e-130	459.00
IUUC-Dno-029928	Dasypus novemcinctus	88.89	0.00e+00	660.00
IUUC-Dor-030238	Dipodomys ordii	76.54	1.00e-176	612.00
IUUC-Dse-031266	Dothistroma septosporum	60.46	4.00e-91	328.00
IUUC-Dme-032007	Drosophila melanogaster	61.22	1.00e-99	356.00
IUUC-Ete-032911	Echinops telfairi	72.97	7.00e-142	496.00
IUUC-Eca-033749	Equus caballus	88.11	0.00e+00	697.00
IUUC-Eeu-035170	Erinaceus europaeus	86.17	0.00e+00	703.00
IUUC-Fca-035498	Felis catus	88.24	0.00e+00	700.00
IUUC-Fal-037397	Ficedula albicollis	67.87	7.00e-149	520.00
IUUC-Fox-037747	Fusarium oxysporum	57.25	2.00e-89	322.00
IUUC-Fso-038429	Fusarium solani	56.43	5.00e-89	320.00
IUUC-Gmo-039378	Gadus morhua	59.32	8.00e-127	446.00
IUUC-Ggr-039939	Gaeumannomyces graminis	57.59	5.00e-94	337.00
IUUC-Gga-040187	Gallus gallus	70.39	3.00e-152	531.00
IUUC-Gac-042223	Gasterosteus aculeatus	61.22	1.00e-131	462.00
IUUC-Gma-042870	Glycine max	65.30	1.00e-97	349.00
IUUC-Ggo-045617	Gorilla gorilla	85.64	0.00e+00	705.00
IUUC-Hsa-046968	Homo sapiens	86.39	0.00e+00	708.00
IUUC-Hvu-047072	Hordeum vulgare	52.73	4.00e-79	287.00
IUUC-Itr-048233	Ictidomys tridecemlineatus	72.95	7.00e-166	576.00
IUUC-Kpa-049093	Komagataella pastoris	55.17	8.00e-76	276.00
IUUC-Lch-050346	Latimeria chalumnae	66.42	4.00e-147	514.00
IUUC-Lpe-051466	Leersia perrieri	66.17	2.00e-103	368.00
IUUC-Lma-053006	Leptosphaeria maculans	58.05	7.00e-88	317.00
IUUC-Mcc-055245	Macaca mulatta	85.39	1.00e-180	625.00
IUUC-Mor-056952	Magnaporthe oryzae	55.33	1.00e-90	326.00
IUUC-Mpo-057605	Magnaporthe poae	57.19	2.00e-95	342.00
IUUC-Mtr-057726	Medicago truncatula	65.41	9.00e-104	369.00
IUUC-Mla-059174	Melampsora laricipopulina	62.55	3.00e-97	348.00
IUUC-Mga-059562	Meleagris gallopavo	59.85	9.00e-118	416.00
IUUC-Mvi-060305	Microbotryum violaceum	59.49	2.00e-91	329.00
IUUC-Mmr-061588	Microcebus murinus	84.58	0.00e+00	701.00
IUUC-Mdo-061914	Monodelphis domestica	79.12	1.00e-178	619.00
IUUC-Mmu-063288	Mus musculus	80.74	0.00e+00	645.00
IUUC-Mac-064969	Musa acuminata	65.56	2.00e-104	371.00
IUUC-Mpu-066855	Mustela putorius furo	88.11	0.00e+00	698.00
IUUC-Mlu-068046	Myotis lucifugus	87.60	0.00e+00	692.00
IUUC-Nfi-068527	Neosartorya fischeri	59.22	7.00e-85	307.00
IUUC-Ncr-068678	Neurospora crassa	58.84	3.00e-92	332.00
IUUC-Nle-069848	Nomascus leucogenys	86.39	0.00e+00	709.00
IUUC-Opr-070589	Ochotona princeps	79.95	2.00e-180	624.00
IUUC-Ont-071733	Oreochromis niloticus	61.83	1.00e-124	439.00
IUUC-Oan-073399	Ornithorhynchus anatinus	87.46	6.00e-150	523.00
IUUC-Ocu-074063	Oryctolagus cuniculus	83.91	0.00e+00	695.00
IUUC-Oba-075264	Oryza barthii	62.90	3.00e-102	364.00
IUUC-Obr-076048	Oryza brachyantha	65.53	6.00e-102	363.00
IUUC-Ogl-077637	Oryza glaberrima	65.91	5.00e-102	363.00
IUUC-Ogu-078830	Oryza glumaepatula	62.90	2.00e-102	365.00
IUUC-Oin-079150	Oryza indica	62.90	2.00e-102	365.00
IUUC-Olo-080398	Oryza longistaminata	56.72	2.00e-80	291.00
IUUC-Ome-081544	Oryza meridionalis	54.75	5.00e-88	317.00
IUUC-Oni-082250	Oryza nivara	62.90	2.00e-102	365.00
IUUC-Opu-083638	Oryza punctata	63.16	8.00e-103	366.00
IUUC-Oru-084981	Oryza rufipogon	62.90	1.00e-102	365.00
IUUC-Osa-085961	Oryza sativa	62.90	1.00e-102	365.00
IUUC-Olu-087880	Ostreococcus lucimarinus	68.32	4.00e-108	384.00
IUUC-Oga-088891	Otolemur garnettii	85.75	0.00e+00	680.00
IUUC-Oar-090021	Ovis aries	85.89	0.00e+00	681.00
IUUC-Ptr-091458	Pan troglodytes	86.14	0.00e+00	707.00
IUUC-Pan-092546	Papio anubis	85.40	0.00e+00	634.00
IUUC-Psi-093280	Pelodiscus sinensis	71.95	1.00e-159	555.00
IUUC-Pma-094298	Petromyzon marinus	77.04	1.00e-120	425.00
IUUC-Pno-094847	Phaeosphaeria nodorum	58.80	1.00e-87	316.00
IUUC-Ppa-095855	Physcomitrella patens	61.99	3.00e-106	377.00
IUUC-Pfo-096428	Poecilia formosa	60.92	2.00e-128	452.00
IUUC-Pab-098696	Pongo abelii	85.43	0.00e+00	688.00
IUUC-Pop-099405	Populus trichocarpa	63.67	1.00e-103	369.00
IUUC-Pca-100740	Procavia capensis	87.87	0.00e+00	728.00
IUUC-Ppe-101854	Prunus persica	63.16	5.00e-105	374.00
IUUC-Pva-103212	Pteropus vampyrus	86.05	0.00e+00	682.00
IUUC-Pgr-103474	Puccinia graminis	62.50	2.00e-97	348.00
IUUC-Ptt-103933	Puccinia triticina	49.05	1.00e-62	233.00
IUUC-Pte-104089	Pyrenophora teres	58.43	9.00e-88	317.00
IUUC-Pyt-104555	Pyrenophora triticirepentis	48.20	6.00e-88	317.00
IUUC-Rno-105057	Rattus norvegicus	80.99	0.00e+00	649.00
IUUC-Sha-107137	Sarcophilus harrisii	81.40	0.00e+00	631.00
IUUC-Sja-107767	Schizosaccharomyces japonicus	61.39	1.00e-97	349.00
IUUC-Spo-108078	Schizosaccharomyces pombe	63.08	7.00e-100	357.00
IUUC-Smo-109288	Selaginella moellendorffii	67.42	5.00e-107	380.00
IUUC-Sit-110246	Setaria italica	62.46	3.00e-102	364.00
IUUC-Sly-111379	Solanum lycopersicum	64.60	2.00e-105	374.00
IUUC-Stu-112777	Solanum tuberosum	61.72	1.00e-103	369.00
IUUC-Sbi-114325	Sorghum bicolor	62.86	5.00e-102	363.00
IUUC-Sre-115203	Sporisorium reilianum	58.65	1.00e-79	290.00
IUUC-Ssc-115361	Sus scrofa	85.61	0.00e+00	691.00
IUUC-Tgu-116967	Taeniopygia guttata	71.05	3.00e-146	511.00
IUUC-Tru-117570	Takifugu rubripes	61.77	5.00e-135	473.00
IUUC-Tsy-119280	Tarsius syrichta	64.02	1.00e-134	472.00
IUUC-Tni-120721	Tetraodon nigroviridis	63.04	4.00e-133	467.00
IUUC-Tca-121494	Theobroma cacao	64.79	5.00e-103	367.00
IUUC-Tre-121869	Trichoderma reesei	54.77	7.00e-92	330.00
IUUC-Tvi-122510	Trichoderma virens	56.04	4.00e-92	331.00
IUUC-Tae-123071	Triticum aestivum	62.32	3.00e-102	364.00
IUUC-Tur-126240	Triticum urartu	62.32	1.00e-101	362.00
IUUC-Tme-126921	Tuber melanosporum	60.22	9.00e-95	340.00
IUUC-Tbe-127872	Tupaia belangeri	80.10	7.00e-178	616.00
IUUC-Ttr-129134	Tursiops truncatus	87.86	0.00e+00	667.00
IUUC-Uma-129412	Ustilago maydis	57.93	8.00e-78	284.00
IUUC-Vda-130003	Verticillium dahliae	47.96	2.00e-92	332.00
IUUC-Vvi-131272	Vitis vinifera	65.41	1.00e-103	369.00
IUUC-Xtr-132019	Xenopus tropicalis	64.75	3.00e-150	524.00
IUUC-Xma-134203	Xiphophorus maculatus	60.95	5.00e-134	470.00
IUUC-Yli-134503	Yarrowia lipolytica	54.23	4.00e-85	308.00
IUUC-Zma-135232	Zea mays	64.79	4.00e-102	364.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence