iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Kpa-049268

Ensembl Protein ID

CAY69715

UniProt Accession

C4R2J1; C4R2J1_KOMPG

Genbank Protein ID

CAY69715.1

Protein Name

Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins

Genbank Nucleotide ID

FN392320

Gene Name

PAS_chr2-2_0203

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
PAS_chr2-2_0203	CAY69715	CAY69715

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.80e-58	196.3	35	477

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkk...avsprellkalkkeaee..fsgyeqqDaqEfla 97
           Gl N gNtC+mNSv+QcL++ +el ++l       + +    +++ +++k+l++l+ +l +++ k    +++++llk+l +  ++  f gy+q+DaqEf +
   Q: 35   GLFNDGNTCFMNSVIQCLASSNELCDFLDL-----ITK----SEDRSFSKELKRLIDNLNSRHGKkvvTYKTNRLLKSLTNGPNKrlFLGYDQEDAQEFYQ 126
           999**********************99998.....332....35679************844444233567778999998765555699************ PP
   S: 98   flldqleeelkkeknkpkeeeeeedkselsde..............................aeekkkkknkslisdlFqgqlksqikclecdnvs.sree 167
            +++qle+++k  ++k+++e +  d                                     a + ++k ++  + +  +g   ++i cl+c++    r++
   Q: 127  LIMQQLEKDIKPDQEKKQKEVNPRDL-----FvprtndmvygletlgalgkcyvpalqvdpsAVDAEEKVYPLELLTPVDGLSCERIGCLTCGEMGgIRYS 222
           **********6655555555555543.....14445689*********************9988999999999999999****************99**** PP
   S: 168  pfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck......................................................kk 214
           +   + l++p++++    sl+++L+ + ++e +e+   ++c +c                                                       kk
   Q: 223  TISGIGLNLPSSKQP-SISLTSLLDTWIAPEVIED---VECVRCGlrqikqfvqgsldaasneklravfqsrideidselskpvineevykklhtknmiKK 319
           ***********9977.6799*************97...889999988999999999999999999999999999999999999999999999999999999 PP
   S: 215  qeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke.......................................kk 276
           ++ +k++ +++ P+ L++h++R  f+ ++++ +k+n kv f ++Ldls++++ p++ + +                                       + 
   Q: 320  SKKVKQIFFSRPPPLLCVHINRSVFDPNTYMIRKNNAKVVFSERLDLSNYVAVPDDVNMDarlsfrkqdqgkekswtqefseeehgiqdqdeddvtdvgPL 420
           99*************************************************996654444666666666667777888888888888889999999999** PP
   S: 277  kYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYk 336
           +Y+L ++++H+G+++ GHY+a+ k  +g W++++D++Vt+++ +evl++  s  +++fY+
   Q: 421  TYSLKSIICHYGTHNYGHYIAFRKY-RGVWWRISDETVTVSDLQEVLNT--SGTFMMFYE 477
           *************************.999*******************4..899*****8 PP

Organism

Komagataella pastoris

Protein Sequence
(Fasta)

MDRFNPLRNR RLYNNNPEQQ RSLSLALANG GCIGGLFNDG NTCFMNSVIQ CLASSNELCD 60
FLDLITKSED RSFSKELKRL IDNLNSRHGK KVVTYKTNRL LKSLTNGPNK RLFLGYDQED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAGAT TTAATCCTCT TAGAAATAGA AGGCTGTACA ACAACAATCC CGAGCAGCAG 60
CGTAGCCTTT CTTTAGCACT TGCAAATGGT GGCTGTATTG GAGGACTATT CAATGATGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ppa:PAS_chr2-2_0203

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005754	Arabidopsis lyrata	22.47	1.00e-17	82.00
IUUC-Ago-007761	Ashbya gossypii	41.87	7.00e-86	309.00
IUUC-Acl-008136	Aspergillus clavatus	27.59	2.00e-37	148.00
IUUC-Afl-008729	Aspergillus flavus	27.87	5.00e-34	137.00
IUUC-Afu-009119	Aspergillus fumigatus	25.91	2.00e-34	138.00
IUUC-Ani-009286	Aspergillus nidulans	24.62	5.00e-35	140.00
IUUC-Ang-009521	Aspergillus niger	27.22	9.00e-35	139.00
IUUC-Aor-009965	Aspergillus oryzae	28.16	1.00e-36	145.00
IUUC-Ate-010591	Aspergillus terreus	27.92	6.00e-41	160.00
IUUC-Ame-010896	Astyanax mexicanus	21.49	2.00e-18	85.10
IUUC-Bgr-012133	Blumeria graminis	26.21	5.00e-34	137.00
IUUC-Bci-013590	Botrytis cinerea	25.41	5.00e-30	124.00
IUUC-Cel-018389	Caenorhabditis elegans	42.31	8.00e-10	57.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	27.11	1.00e-32	132.00
IUUC-Cne-027061	Cryptococcus neoformans	24.40	3.00e-13	68.20
IUUC-Dre-027563	Danio rerio	21.72	2.00e-20	91.70
IUUC-Dse-031252	Dothistroma septosporum	26.85	2.00e-28	118.00
IUUC-Fox-037820	Fusarium oxysporum	30.14	3.00e-20	90.90
IUUC-Fso-038309	Fusarium solani	25.87	6.00e-34	136.00
IUUC-Gmo-038726	Gadus morhua	21.70	6.00e-17	79.70
IUUC-Ggr-040099	Gaeumannomyces graminis	27.37	1.00e-17	83.20
IUUC-Lch-050662	Latimeria chalumnae	22.68	2.00e-19	88.60
IUUC-Lpe-051078	Leersia perrieri	19.92	1.00e-11	62.80
IUUC-Lma-053048	Leptosphaeria maculans	27.56	2.00e-30	125.00
IUUC-Mor-057143	Magnaporthe oryzae	25.22	1.00e-26	112.00
IUUC-Mpo-057548	Magnaporthe poae	25.72	3.00e-19	88.60
IUUC-Mla-058970	Melampsora laricipopulina	25.10	2.00e-30	125.00
IUUC-Mga-059543	Meleagris gallopavo	21.53	2.00e-14	71.60
IUUC-Mvi-060332	Microbotryum violaceum	22.79	2.00e-18	85.50
IUUC-Nfi-068306	Neosartorya fischeri	26.09	5.00e-39	153.00
IUUC-Ncr-068741	Neurospora crassa	23.62	1.00e-22	99.80
IUUC-Oba-075765	Oryza barthii	20.66	3.00e-12	64.30
IUUC-Ogu-078263	Oryza glumaepatula	20.27	2.00e-11	62.00
IUUC-Oni-082424	Oryza nivara	20.27	3.00e-10	57.80
IUUC-Opu-083371	Oryza punctata	20.93	2.00e-13	69.30
IUUC-Oru-085117	Oryza rufipogon	20.27	3.00e-10	57.80
IUUC-Psi-093451	Pelodiscus sinensis	22.00	3.00e-14	70.90
IUUC-Pno-094855	Phaeosphaeria nodorum	29.51	6.00e-17	79.30
IUUC-Pgr-103423	Puccinia graminis	25.71	4.00e-23	101.00
IUUC-Ptt-103779	Puccinia triticina	25.62	2.00e-23	102.00
IUUC-Pte-104330	Pyrenophora teres	26.81	2.00e-29	121.00
IUUC-Pyt-104518	Pyrenophora triticirepentis	27.33	6.00e-33	134.00
IUUC-Sce-106422	Saccharomyces cerevisiae	44.51	2.00e-80	291.00
IUUC-Spo-108133	Schizosaccharomyces pombe	39.66	9.00e-10	55.50
IUUC-Ssl-108648	Sclerotinia sclerotiorum	26.13	4.00e-31	127.00
IUUC-Sre-114910	Sporisorium reilianum	24.36	8.00e-33	133.00
IUUC-Tgu-117446	Taeniopygia guttata	23.27	9.00e-20	89.40
IUUC-Tru-118268	Takifugu rubripes	21.38	2.00e-14	71.60
IUUC-Tre-122225	Trichoderma reesei	27.95	4.00e-28	117.00
IUUC-Tvi-122277	Trichoderma virens	27.48	1.00e-37	149.00
IUUC-Tme-126935	Tuber melanosporum	29.32	4.00e-32	131.00
IUUC-Uma-129375	Ustilago maydis	24.54	8.00e-31	126.00
IUUC-Vda-129789	Verticillium dahliae	25.34	6.00e-26	110.00
IUUC-Xtr-132374	Xenopus tropicalis	23.01	6.00e-19	86.70
IUUC-Yli-134571	Yarrowia lipolytica	32.93	3.00e-52	197.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence