iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004521

UUCD1 version

UUC-AnC-00809

Ensembl Protein ID

ENSACAP00000014864.3

UniProt Accession

G1KQQ3; G1KQQ3_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HECTD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000015118.3	ENSACAT00000015164.3	ENSACAP00000014864.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.50e-123	409.9	2112	2570

Active Site

Position(s)	Description	Evidence
2539	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysen..dketlqpnpdsglknp..................... 65
           ++d+k++levef+gEeg++l G+t+ef+al+++e+q+++lg++l++++  d+e++q++   glk+p                     
   Q: 2112 HADRKSVLEVEFLGEEGTGL-GPTLEFYALVAAEFQRTELGAWLCDDDfpDDESRQVDIGGGLKPPgyyvqrscglftapfpqdsde 2197
           6899****************.******************************************988********************* PP
   S: 66   ..ehlklFeflGrllgkalqdgrlldlplsksfykll.................................................. 100
             + +klF+flG++l+k++qd+rl+dlp+sk+f+kl+                                                  
   Q: 2198 leRITKLFHFLGIFLAKCIQDNRLVDLPISKPFFKLMcmgdiksnmskliyesrgdrdlhctesqseasteeghdslsvgsfeedsk 2284
           *************************************99999999999999999999999999999999999999988888888887 PP
   S: 101  ...............lgkklsledleevdpelykslkeikenaes..................................dieelgld 138
                          ++  l++ed+e v+p+++++lkeik++a +                                  +ie+lgl+
   Q: 2285 sefildppkpkppawFNGILTWEDFELVNPHRARFLKEIKDLAIKrrqilsnkglsedekntklqelmmknrsgsgpalSIEDLGLN 2371
           7777777777766666668***********************9334445555666667778888889999999999999******** PP
   S: 139  ltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeid 225
           ++f++s++++g t+++ LkpgGe++ Vt++N+eeYv+l++++++++gi++q++afr+Gfn+v+p+e+ls+F++ee+++++cG+   +
   Q: 2372 FQFCPSSRVYGFTAVD-LKPGGEDELVTMDNAEEYVDLMFDFCMHTGIQKQMDAFRDGFNRVFPMEKLSSFSHEEVQMILCGN---Q 2454
           *************999.******************************************************************...6 PP
   S: 226  vedlkket..ky...kggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfn 306
           ++++++e+  +y   k gyt+dsp++ +F++vl+++ss+erkafLqF+Tg+s+lP+gG+a+l+prl+v+rk da+d+++Ps+nTC++
   Q: 2455 SPSWAAEDiiNYtepKLGYTRDSPGFLRFVRVLCGMSSDERKAFLQFTTGCSTLPPGGLANLHPRLTVVRKvDATDASYPSVNTCVH 2541
           666666665555555************************************************************************ PP
   S: 307  yLkLPeYsskeilkekLlyAieetkgFels 336
           yLkLPeYss+ei++e+Ll+A++e kgF+l+
   Q: 2542 YLKLPEYSSEEIMRERLLAATME-KGFHLN 2570
           ***********************.****86 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MADVDPDTLL EWLQMGQGDE RDMQLIALEQ LCMLLLMSDN VDRCFETCPP RTFLPALCKI 60
FLDESAPDNV LEVTARAITY YLDVSAERTR RIVGVDGAIK ALCNRLVVVE LNNRTSRDLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCAACCTAG AGGCATGGAT GAGGGGTTGT GCTGTCAATT TTCGAGGTTG TGGGGTGTTT 60
ACTTTTGTTG TTTTGTCCGC TGCCGTGATG CCATCACTCT TTTATATATA TAGATAGATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR008979--Galactose-bd-like
IPR000569--HECT_dom
IPR010606--Mib_Herc2
IPR012919--SUN_dom

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50237--HECT
PS51416--MIB_HERC2

Pfam

PF12796--Ank_2
PF00632--HECT
PF06701--MIB_HERC2
PF07738--Sad1_UNC

SMART

SM00248--ANK
SM00119--HECTc

Gene Ontology

GO:0046872--F:metal ion binding
GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000538	Aegilops tauschii	39.48	1.00e-41	165.00
IUUC-Aml-001987	Ailuropoda melanoleuca	96.77	0.00e+00	2838.00
IUUC-Atr-002821	Amborella trichopoda	41.06	1.00e-49	192.00
IUUC-Apl-003493	Anas platyrhynchos	97.74	0.00e+00	2874.00
IUUC-Aly-006493	Arabidopsis lyrata	36.43	7.00e-44	172.00
IUUC-Ath-006679	Arabidopsis thaliana	36.08	1.00e-42	169.00
IUUC-Ago-007875	Ashbya gossypii	40.11	1.00e-31	132.00
IUUC-Acl-008242	Aspergillus clavatus	36.95	2.00e-37	151.00
IUUC-Afl-008736	Aspergillus flavus	34.16	2.00e-35	145.00
IUUC-Afu-008812	Aspergillus fumigatus	35.92	3.00e-37	151.00
IUUC-Ani-009407	Aspergillus nidulans	35.10	4.00e-36	147.00
IUUC-Ang-009763	Aspergillus niger	35.51	2.00e-35	145.00
IUUC-Aor-009941	Aspergillus oryzae	34.16	2.00e-35	144.00
IUUC-Ate-010459	Aspergillus terreus	33.45	3.00e-35	144.00
IUUC-Ame-011258	Astyanax mexicanus	91.61	0.00e+00	2386.00
IUUC-Bgr-012265	Blumeria graminis	35.47	1.00e-38	156.00
IUUC-Bta-012835	Bos taurus	96.41	0.00e+00	2835.00
IUUC-Bci-013890	Botrytis cinerea	33.98	4.00e-37	150.00
IUUC-Bdi-014961	Brachypodium distachyon	33.33	4.00e-78	286.00
IUUC-Bol-015440	Brassica oleracea	29.41	9.00e-51	196.00
IUUC-Bra-016648	Brassica rapa	29.46	5.00e-50	193.00
IUUC-Cel-018153	Caenorhabditis elegans	52.55	1.00e-171	598.00
IUUC-Cja-019174	Callithrix jacchus	94.94	0.00e+00	2751.00
IUUC-Cfa-021115	Canis familiaris	96.17	0.00e+00	2782.00
IUUC-Cpo-022382	Cavia porcellus	90.25	0.00e+00	2584.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	39.84	3.00e-41	162.00
IUUC-Csa-023230	Chlorocebus sabaeus	96.59	0.00e+00	2833.00
IUUC-Cho-024711	Choloepus hoffmanni	93.36	0.00e+00	1608.00
IUUC-Cin-025342	Ciona intestinalis	52.96	0.00e+00	1378.00
IUUC-Csv-026031	Ciona savignyi	52.24	0.00e+00	1412.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	34.05	7.00e-39	156.00
IUUC-Cne-026857	Cryptococcus neoformans	33.79	3.00e-34	141.00
IUUC-Cme-027226	Cyanidioschyzon merolae	36.24	3.00e-32	134.00
IUUC-Dre-027435	Danio rerio	90.29	0.00e+00	2629.00
IUUC-Dno-029954	Dasypus novemcinctus	96.65	0.00e+00	2806.00
IUUC-Dor-030734	Dipodomys ordii	92.89	0.00e+00	1411.00
IUUC-Dse-031444	Dothistroma septosporum	32.34	2.00e-37	152.00
IUUC-Dme-031739	Drosophila melanogaster	59.93	0.00e+00	1631.00
IUUC-Ete-033192	Echinops telfairi	89.52	0.00e+00	1173.00
IUUC-Eca-033434	Equus caballus	95.41	0.00e+00	2789.00
IUUC-Eeu-035031	Erinaceus europaeus	81.65	0.00e+00	1066.00
IUUC-Fca-035998	Felis catus	94.02	0.00e+00	2720.00
IUUC-Fal-037468	Ficedula albicollis	96.63	0.00e+00	4477.00
IUUC-Fox-038035	Fusarium oxysporum	35.23	8.00e-40	158.00
IUUC-Fso-038320	Fusarium solani	34.29	2.00e-38	155.00
IUUC-Gmo-038495	Gadus morhua	91.20	0.00e+00	1370.00
IUUC-Ggr-040057	Gaeumannomyces graminis	33.77	4.00e-39	157.00
IUUC-Gga-040736	Gallus gallus	97.63	0.00e+00	4479.00
IUUC-Gac-041777	Gasterosteus aculeatus	91.65	0.00e+00	2399.00
IUUC-Gma-044152	Glycine max	41.73	4.00e-49	190.00
IUUC-Ggo-044677	Gorilla gorilla	92.30	0.00e+00	2651.00
IUUC-Hsa-045879	Homo sapiens	96.59	0.00e+00	2833.00
IUUC-Hvu-047700	Hordeum vulgare	38.83	5.00e-43	169.00
IUUC-Itr-048664	Ictidomys tridecemlineatus	96.53	0.00e+00	2833.00
IUUC-Kpa-049098	Komagataella pastoris	37.97	2.00e-34	142.00
IUUC-Lch-050444	Latimeria chalumnae	94.69	0.00e+00	2694.00
IUUC-Lpe-051372	Leersia perrieri	37.46	3.00e-42	167.00
IUUC-Loc-051986	Lepisosteus oculatus	90.32	0.00e+00	2625.00
IUUC-Lma-052990	Leptosphaeria maculans	34.62	2.00e-39	158.00
IUUC-Laf-054230	Loxodonta africana	96.12	0.00e+00	2766.00
IUUC-Mcc-054787	Macaca mulatta	96.59	0.00e+00	2833.00
IUUC-Meu-056502	Macropus eugenii	88.37	0.00e+00	1321.00
IUUC-Mor-057054	Magnaporthe oryzae	33.22	1.00e-38	156.00
IUUC-Mpo-057417	Magnaporthe poae	33.91	7.00e-39	156.00
IUUC-Mtr-058626	Medicago truncatula	38.43	3.00e-44	174.00
IUUC-Mla-058870	Melampsora laricipopulina	37.56	1.00e-38	155.00
IUUC-Mga-059409	Meleagris gallopavo	98.43	0.00e+00	1939.00
IUUC-Mvi-060507	Microbotryum violaceum	37.50	4.00e-40	161.00
IUUC-Mmr-061667	Microcebus murinus	95.72	0.00e+00	2800.00
IUUC-Mdo-061960	Monodelphis domestica	96.72	0.00e+00	2827.00
IUUC-Mmu-063941	Mus musculus	95.53	0.00e+00	2775.00
IUUC-Mac-065046	Musa acuminata	36.64	6.00e-42	166.00
IUUC-Mpu-065939	Mustela putorius furo	96.53	0.00e+00	2830.00
IUUC-Mlu-068112	Myotis lucifugus	96.41	0.00e+00	2829.00
IUUC-Nfi-068482	Neosartorya fischeri	35.92	3.00e-37	151.00
IUUC-Ncr-068906	Neurospora crassa	36.19	2.00e-38	155.00
IUUC-Nle-069001	Nomascus leucogenys	96.59	0.00e+00	2833.00
IUUC-Opr-071222	Ochotona princeps	92.96	0.00e+00	2080.00
IUUC-Ont-072101	Oreochromis niloticus	86.66	0.00e+00	2627.00
IUUC-Oan-072814	Ornithorhynchus anatinus	96.77	0.00e+00	2819.00
IUUC-Ocu-074011	Oryctolagus cuniculus	96.65	0.00e+00	2835.00
IUUC-Oba-075424	Oryza barthii	31.03	7.00e-65	242.00
IUUC-Obr-076915	Oryza brachyantha	32.67	4.00e-77	283.00
IUUC-Ogl-077055	Oryza glaberrima	32.39	7.00e-77	283.00
IUUC-Ogu-078341	Oryza glumaepatula	31.03	8.00e-65	242.00
IUUC-Oin-079256	Oryza indica	32.07	6.00e-75	276.00
IUUC-Olo-080343	Oryza longistaminata	32.07	7.00e-75	276.00
IUUC-Ome-081422	Oryza meridionalis	31.90	6.00e-74	273.00
IUUC-Oni-082977	Oryza nivara	31.03	4.00e-65	243.00
IUUC-Opu-083574	Oryza punctata	37.46	1.00e-42	169.00
IUUC-Oru-084742	Oryza rufipogon	31.03	4.00e-65	243.00
IUUC-Osa-085972	Oryza sativa	32.39	1.00e-76	280.00
IUUC-Ola-086412	Oryzias latipes	91.58	0.00e+00	2409.00
IUUC-Olu-087871	Ostreococcus lucimarinus	33.33	1.00e-33	137.00
IUUC-Oga-087908	Otolemur garnettii	37.36	2.00e-47	185.00
IUUC-Oar-089668	Ovis aries	96.41	0.00e+00	2828.00
IUUC-Ptr-090517	Pan troglodytes	95.82	0.00e+00	2785.00
IUUC-Pan-091849	Papio anubis	93.31	0.00e+00	2701.00
IUUC-Psi-093390	Pelodiscus sinensis	95.56	0.00e+00	4388.00
IUUC-Pma-094628	Petromyzon marinus	83.30	0.00e+00	1598.00
IUUC-Pno-094891	Phaeosphaeria nodorum	36.40	4.00e-38	154.00
IUUC-Ppa-095264	Physcomitrella patens	32.71	2.00e-82	301.00
IUUC-Pfo-097075	Poecilia formosa	85.03	0.00e+00	2872.00
IUUC-Pab-098176	Pongo abelii	96.59	0.00e+00	2833.00
IUUC-Pop-099725	Populus trichocarpa	37.25	3.00e-37	151.00
IUUC-Pca-101123	Procavia capensis	90.35	0.00e+00	1555.00
IUUC-Ppe-101229	Prunus persica	35.23	1.00e-41	165.00
IUUC-Pva-103008	Pteropus vampyrus	98.18	0.00e+00	1578.00
IUUC-Pgr-103694	Puccinia graminis	30.29	4.00e-60	227.00
IUUC-Ptt-103916	Puccinia triticina	27.91	6.00e-49	190.00
IUUC-Pte-104346	Pyrenophora teres	35.63	2.00e-38	155.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	36.40	3.00e-39	158.00
IUUC-Rno-105885	Rattus norvegicus	96.17	0.00e+00	2825.00
IUUC-Sce-106273	Saccharomyces cerevisiae	34.02	1.00e-29	125.00
IUUC-Sha-107048	Sarcophilus harrisii	96.02	0.00e+00	2806.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	37.34	2.00e-35	145.00
IUUC-Spo-108081	Schizosaccharomyces pombe	36.77	5.00e-36	147.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	33.98	1.00e-37	152.00
IUUC-Smo-109590	Selaginella moellendorffii	41.15	4.00e-43	171.00
IUUC-Sit-110717	Setaria italica	31.27	1.00e-78	288.00
IUUC-Sly-111552	Solanum lycopersicum	40.19	2.00e-39	158.00
IUUC-Stu-112896	Solanum tuberosum	41.50	1.00e-47	184.00
IUUC-Sar-113071	Sorex araneus	92.40	0.00e+00	1264.00
IUUC-Sbi-113884	Sorghum bicolor	33.00	1.00e-77	285.00
IUUC-Sre-114993	Sporisorium reilianum	40.09	3.00e-40	161.00
IUUC-Ssc-115963	Sus scrofa	96.05	0.00e+00	2817.00
IUUC-Tgu-117167	Taeniopygia guttata	96.86	0.00e+00	1673.00
IUUC-Tru-118626	Takifugu rubripes	86.29	0.00e+00	2627.00
IUUC-Tsy-119504	Tarsius syrichta	93.36	0.00e+00	2248.00
IUUC-Tni-119877	Tetraodon nigroviridis	91.96	0.00e+00	2413.00
IUUC-Tca-121574	Theobroma cacao	30.61	2.00e-37	152.00
IUUC-Tre-122195	Trichoderma reesei	30.23	1.00e-70	262.00
IUUC-Tvi-122650	Trichoderma virens	29.46	3.00e-68	254.00
IUUC-Tae-123099	Triticum aestivum	39.77	3.00e-47	184.00
IUUC-Tur-126730	Triticum urartu	39.52	8.00e-45	176.00
IUUC-Tme-126964	Tuber melanosporum	35.00	2.00e-40	162.00
IUUC-Tbe-127602	Tupaia belangeri	95.75	0.00e+00	989.00
IUUC-Ttr-128394	Tursiops truncatus	96.04	0.00e+00	1666.00
IUUC-Uma-129365	Ustilago maydis	40.09	3.00e-40	161.00
IUUC-Vda-129725	Verticillium dahliae	37.50	8.00e-41	163.00
IUUC-Vpa-130280	Vicugna pacos	95.76	0.00e+00	2802.00
IUUC-Vvi-130904	Vitis vinifera	39.11	6.00e-47	183.00
IUUC-Xtr-131787	Xenopus tropicalis	83.33	0.00e+00	3958.00
IUUC-Xma-133497	Xiphophorus maculatus	82.78	0.00e+00	1507.00
IUUC-Yli-134481	Yarrowia lipolytica	37.35	1.00e-36	149.00
IUUC-Zma-135769	Zea mays	36.90	4.00e-40	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence