iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052769

Ensembl Protein ID

ENSLOCP00000016049.1

UniProt Accession

W5N5Z0; W5N5Z0_LEPOC

Genbank Protein ID

ENSLOCP00000016049

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01026084

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000013028.1	ENSLOCT00000016079.1	ENSLOCP00000016049.1
ENSLOCG00000013028.1	ENSLOCT00000016085.1	ENSLOCP00000016055.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.70e-107	358.6	743	1073

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtCYmNS+LQcL n+p +++++++  + e++n++n  ++kge++++++ ++++lw++  k +spr+++ +++k++ +f++
   Q: 743  TGLRNLGNTCYMNSILQCLCNTPGMTDYFNKnYYLEDINRSNILGHKGEVAEEFAVIMKALWSGLYKCISPRDFKITIGKINDRFTS 829
           7*****************************977889*************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
            ++qD+qE+l fl+d+l+e+l+k +n ++ +ee +d  +l+d      a++k+k  n+s+i+ lFqgq+ks+++cl+c+++s ++e+
   Q: 830  CDHQDSQELLLFLMDGLHEDLNKADNRKRYKEETND--HLDDFkaaelAWSKHKLLNESIIVALFQGQFKSTVQCLTCHKKSRTFET 914
           *********************884444444433333..3444444555*************************************** PP
   S: 169  fldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvef 255
           f++lsl++ +++++   +lqdcL++f+kee+l+++nk++c++ck +++a+kkl+++klP++L +hLkRfs++ +   r+k++++v+f
   Q: 915  FMYLSLQLTSSNKC---TLQDCLKAFSKEEKLTDSNKVECNNCKTRRDATKKLEIWKLPPILLVHLKRFSYEGR--WRQKLQTYVDF 996
           *************9...****************************************************99665..556******** PP
   S: 256  ple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           ple Ldls++++ p+ +    k+Y+L++v +H+G++++GHY+ay+kn  ++ W++fdD+ ++e++ ++v++   s aY+lfY 
   Q: 997  PLEnLDLSQYVIGPKHN---LKRYNLYGVSNHYGGMDGGHYTAYCKNGLKQrWYKFDDHDISELSASSVKS---SAAYILFYS 1073
           *************9987...69*************************66656*******************...********7 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MPTVSAGAKE LYLSTSLGEL NKKAEVKPDK CSTRSYVQSA CKIFKAAEEC RLDRDEERAY 60
VLYMKYLTVY DLIKKRPDFK QQQEFFLSIL GPSNFKKAIE EAEKLSDSLK LRYEEAEVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTAATTCT TGAATGTTGA ATTATAAAAG CGGTCTTTTT TTCCTAGTTT TATTATCAAT 60
TAATACAAAG AAGATACAGC ATCCAAAACA GAAATGTGAA CAGAAAAGAC TCTTAATTAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR001763--Rhodanese-like_dom
IPR015063--USP8_dimer
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50206--RHODANESE_3
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF08969--USP8_dimer

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001661	Ailuropoda melanoleuca	74.51	0.00e+00	762.00
IUUC-Apl-003226	Anas platyrhynchos	75.34	0.00e+00	760.00
IUUC-Aca-004936	Anolis carolinensis	76.81	0.00e+00	726.00
IUUC-Ago-007959	Ashbya gossypii	34.16	2.00e-52	201.00
IUUC-Acl-008102	Aspergillus clavatus	31.88	2.00e-50	194.00
IUUC-Afl-008604	Aspergillus flavus	33.24	1.00e-50	194.00
IUUC-Afu-009001	Aspergillus fumigatus	31.11	3.00e-49	191.00
IUUC-Ani-009291	Aspergillus nidulans	31.32	6.00e-50	192.00
IUUC-Ang-009844	Aspergillus niger	32.51	4.00e-49	189.00
IUUC-Aor-010098	Aspergillus oryzae	33.24	4.00e-50	193.00
IUUC-Ate-010585	Aspergillus terreus	32.05	1.00e-49	191.00
IUUC-Ame-011029	Astyanax mexicanus	88.42	8.00e-47	180.00
IUUC-Bta-013008	Bos taurus	77.50	0.00e+00	754.00
IUUC-Cel-018482	Caenorhabditis elegans	30.90	2.00e-51	197.00
IUUC-Cja-019173	Callithrix jacchus	74.75	0.00e+00	753.00
IUUC-Cfa-021243	Canis familiaris	74.95	0.00e+00	761.00
IUUC-Cpo-021522	Cavia porcellus	75.98	0.00e+00	745.00
IUUC-Cre-022582	Chlamydomonas reinhardtii	43.60	7.00e-77	280.00
IUUC-Csa-023616	Chlorocebus sabaeus	74.75	0.00e+00	750.00
IUUC-Cho-024381	Choloepus hoffmanni	69.06	0.00e+00	637.00
IUUC-Cin-025287	Ciona intestinalis	47.43	8.00e-91	328.00
IUUC-Csv-026253	Ciona savignyi	46.36	1.00e-80	295.00
IUUC-Cne-026821	Cryptococcus neoformans	39.23	9.00e-72	265.00
IUUC-Dre-028440	Danio rerio	73.78	0.00e+00	753.00
IUUC-Dno-029039	Dasypus novemcinctus	73.97	0.00e+00	760.00
IUUC-Dor-031043	Dipodomys ordii	79.37	2.00e-108	387.00
IUUC-Dse-031463	Dothistroma septosporum	29.53	2.00e-42	167.00
IUUC-Dme-032089	Drosophila melanogaster	47.65	2.00e-85	310.00
IUUC-Ete-033040	Echinops telfairi	70.94	4.00e-170	592.00
IUUC-Eca-033449	Equus caballus	73.92	0.00e+00	767.00
IUUC-Eeu-034693	Erinaceus europaeus	78.92	2.00e-104	373.00
IUUC-Fca-035794	Felis catus	77.19	0.00e+00	717.00
IUUC-Fal-037322	Ficedula albicollis	74.13	0.00e+00	755.00
IUUC-Gmo-038584	Gadus morhua	68.49	0.00e+00	686.00
IUUC-Gga-041188	Gallus gallus	74.66	0.00e+00	762.00
IUUC-Gac-041850	Gasterosteus aculeatus	77.71	0.00e+00	776.00
IUUC-Ggo-045565	Gorilla gorilla	74.95	0.00e+00	756.00
IUUC-Hsa-046438	Homo sapiens	74.95	0.00e+00	755.00
IUUC-Itr-048883	Ictidomys tridecemlineatus	76.81	0.00e+00	751.00
IUUC-Kpa-049321	Komagataella pastoris	33.52	4.00e-48	186.00
IUUC-Lch-050485	Latimeria chalumnae	77.91	0.00e+00	784.00
IUUC-Lma-053021	Leptosphaeria maculans	31.45	6.00e-52	199.00
IUUC-Laf-053432	Loxodonta africana	76.40	0.00e+00	748.00
IUUC-Mcc-055823	Macaca mulatta	74.75	0.00e+00	754.00
IUUC-Meu-056099	Macropus eugenii	81.41	2.00e-138	486.00
IUUC-Mla-059089	Melampsora laricipopulina	39.78	8.00e-71	262.00
IUUC-Mga-059739	Meleagris gallopavo	73.90	0.00e+00	759.00
IUUC-Mvi-060559	Microbotryum violaceum	40.47	3.00e-76	280.00
IUUC-Mmr-061158	Microcebus murinus	74.03	0.00e+00	756.00
IUUC-Mdo-061801	Monodelphis domestica	76.39	0.00e+00	765.00
IUUC-Mpu-066738	Mustela putorius furo	74.04	0.00e+00	763.00
IUUC-Mlu-067307	Myotis lucifugus	73.54	0.00e+00	762.00
IUUC-Nfi-068410	Neosartorya fischeri	31.39	2.00e-49	191.00
IUUC-Nle-069314	Nomascus leucogenys	74.75	0.00e+00	754.00
IUUC-Opr-070378	Ochotona princeps	72.87	2.00e-104	373.00
IUUC-Ont-071545	Oreochromis niloticus	78.87	0.00e+00	781.00
IUUC-Oan-073537	Ornithorhynchus anatinus	72.34	0.00e+00	749.00
IUUC-Ocu-074193	Oryctolagus cuniculus	76.60	0.00e+00	749.00
IUUC-Ola-086622	Oryzias latipes	79.67	0.00e+00	767.00
IUUC-Oga-088271	Otolemur garnettii	76.65	0.00e+00	754.00
IUUC-Oar-090431	Ovis aries	77.50	0.00e+00	753.00
IUUC-Ptr-091339	Pan troglodytes	75.15	0.00e+00	759.00
IUUC-Pan-092266	Papio anubis	75.00	3.00e-144	504.00
IUUC-Psi-093187	Pelodiscus sinensis	56.08	6.00e-116	411.00
IUUC-Pma-094626	Petromyzon marinus	53.11	1.00e-132	466.00
IUUC-Pfo-096463	Poecilia formosa	78.07	0.00e+00	771.00
IUUC-Pab-097645	Pongo abelii	75.15	0.00e+00	757.00
IUUC-Pva-103222	Pteropus vampyrus	76.71	7.00e-171	594.00
IUUC-Pgr-103408	Puccinia graminis	37.76	2.00e-52	201.00
IUUC-Ptt-103699	Puccinia triticina	46.50	2.00e-65	244.00
IUUC-Pyt-104711	Pyrenophora triticirepentis	29.97	6.00e-50	192.00
IUUC-Rno-105510	Rattus norvegicus	52.80	5.00e-111	395.00
IUUC-Sce-106166	Saccharomyces cerevisiae	36.09	1.00e-51	198.00
IUUC-Sha-106879	Sarcophilus harrisii	74.76	0.00e+00	761.00
IUUC-Sja-107836	Schizosaccharomyces japonicus	34.57	1.00e-47	184.00
IUUC-Smo-108711	Selaginella moellendorffii	32.50	1.00e-46	180.00
IUUC-Sar-113019	Sorex araneus	68.98	0.00e+00	697.00
IUUC-Sre-115031	Sporisorium reilianum	37.22	2.00e-67	251.00
IUUC-Ssc-116334	Sus scrofa	70.21	0.00e+00	707.00
IUUC-Tgu-117062	Taeniopygia guttata	75.95	0.00e+00	755.00
IUUC-Tru-117908	Takifugu rubripes	59.46	0.00e+00	1122.00
IUUC-Tsy-118867	Tarsius syrichta	65.95	0.00e+00	646.00
IUUC-Tni-120206	Tetraodon nigroviridis	76.86	0.00e+00	753.00
IUUC-Tme-127144	Tuber melanosporum	42.37	5.00e-79	289.00
IUUC-Tbe-127877	Tupaia belangeri	77.78	8.00e-64	239.00
IUUC-Ttr-128580	Tursiops truncatus	74.85	0.00e+00	755.00
IUUC-Uma-129340	Ustilago maydis	35.96	3.00e-67	250.00
IUUC-Vpa-130541	Vicugna pacos	70.15	0.00e+00	739.00
IUUC-Xtr-132161	Xenopus tropicalis	67.38	0.00e+00	734.00
IUUC-Xma-134271	Xiphophorus maculatus	78.07	0.00e+00	774.00
IUUC-Yli-134561	Yarrowia lipolytica	35.93	1.00e-57	218.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence