iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-023785

Ensembl Protein ID

ENSCSAP00000000642.1

UniProt Accession

A0A0D9QWA3; A0A0D9QWA3_CHLSB

Genbank Protein ID

ENSCSAP00000000642

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01134247

Gene Name

TRIM22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000004294.1	ENSCSAT00000002322.1	ENSCSAP00000000642.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.70e-09	36.3	15	60
E3 activity/RING/U-box	9.20e-07	28.8	9	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl..qkwpglknssskefrCPlCr 46
           C+iCle + + pl+l+CgH f++ C+  +    ++  + +e +CP+C+
   Q: 15   CPICLELLTE-PLSLDCGHSFCQACItpNS-RESMIGQEGERSCPVCQ 60
           ********99.***************8633.478899**********7 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwl......asggktcPvtrqplteedlvPnltlrrliq 66
           + +e  CpI lel ++P  l +G+++ +++I          ++g+++cPv++++ ++ +l Pn  l ++++
   Q: 9    IEKEVTCPICLELLTEPLSLDCGHSFCQACITPNSresmigQEGERSCPVCQTSYQPGNLRPNRHLANIVE 79
           567899*************************986633334555555******************9988776 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MDSSVKVDIE KEVTCPICLE LLTEPLSLDC GHSFCQACIT PNSRESMIGQ EGERSCPVCQ 60
TSYQPGNLRP NRHLANIVER VKEVKMSPQE GQKRDICEHH GKKLQIFCKE DGKVICWVCE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAAGACTCCT CTACTTTGGA CTGAAGGTGA GTGGGGCAAT TTGTGGGAGC ATAGAATGGG 60
AGGCTTTGAG AAGAATAGGT TGATTGTGTC TGGGTGAGTT TAATTTGTGG TTCTGAAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR003877--SPRY_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00622--SPRY
PF00643--zf-B_box
PF13445--zf-RING_UBOX

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0008270--F:zinc ion binding
GO:0010508--P:positive regulation of autophagy
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0070206--P:protein trimerization
GO:0032880--P:regulation of protein localization

KEGG

csab:103247880

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002371	Ailuropoda melanoleuca	66.47	0.00e+00	685.00
IUUC-Acl-008013	Aspergillus clavatus	58.82	2.00e-06	48.10
IUUC-Ani-009293	Aspergillus nidulans	60.61	4.00e-06	47.00
IUUC-Cel-018370	Caenorhabditis elegans	31.65	7.00e-09	54.70
IUUC-Cfa-021080	Canis familiaris	66.06	0.00e+00	675.00
IUUC-Eeu-034968	Erinaceus europaeus	49.57	3.00e-115	408.00
IUUC-Fca-035533	Felis catus	58.84	2.00e-157	548.00
IUUC-Ggo-044550	Gorilla gorilla	89.36	0.00e+00	865.00
IUUC-Hsa-046363	Homo sapiens	89.96	0.00e+00	905.00
IUUC-Itr-048069	Ictidomys tridecemlineatus	55.74	1.00e-144	506.00
IUUC-Laf-053647	Loxodonta africana	65.33	0.00e+00	637.00
IUUC-Mcc-054743	Macaca mulatta	94.58	0.00e+00	956.00
IUUC-Mmu-063682	Mus musculus	56.02	1.00e-149	522.00
IUUC-Mpu-066674	Mustela putorius furo	65.46	0.00e+00	678.00
IUUC-Nle-068980	Nomascus leucogenys	90.76	0.00e+00	908.00
IUUC-Oga-088267	Otolemur garnettii	57.26	3.00e-148	518.00
IUUC-Ptr-091300	Pan troglodytes	89.56	0.00e+00	897.00
IUUC-Pan-092605	Papio anubis	84.94	0.00e+00	820.00
IUUC-Ppa-095948	Physcomitrella patens	43.10	5.00e-09	53.10
IUUC-Pab-098535	Pongo abelii	90.16	0.00e+00	905.00
IUUC-Rno-105401	Rattus norvegicus	56.43	6.00e-151	527.00
IUUC-Ssc-115715	Sus scrofa	55.91	4.00e-149	521.00
IUUC-Tsy-119330	Tarsius syrichta	75.30	0.00e+00	732.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence